Standout Papers

A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular... 1998 2026 2007 2016 1.7k
  1. A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain (1999)
    Bart De Strooper, Wim Annaert et al. Nature
  2. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein (1998)
    Bart De Strooper, Paul Säftig et al. Nature
  3. Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function (2009)
    Paul Säftig, Judith Klumperman Nature Reviews Molecular Cell Biology
  4. Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands (2004)
    Umut Şahin, Gisela Weskamp et al. The Journal of Cell Biology
  5. Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice (2000)
    Yoshitaka Tanaka, Eeva‐Liisa Eskelinen et al. Nature
  6. Role for Rab7 in maturation of late autophagic vacuoles (2004)
    Stefanie Jäger, Cecilia Bucci et al. Journal of Cell Science
  7. The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis (2011)
    Guillaume van Niel, Stéphanie Charrin et al. Developmental Cell
  8. Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice (1998)
    Paul Säftig, Ernst B. Hunziker et al. Proceedings of the National Academy of Sciences
  9. The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion (2003)
    Christian Hundhausen, Theo A. Berkhout et al. Blood
  10. Autophagy: A lysosomal degradation pathway with a central role in health and disease (2008)
    Eeva‐Liisa Eskelinen, Paul Säftig Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  11. ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and β-catenin translocation (2005)
    Thorsten Maretzky, Karina Reiß et al. Proceedings of the National Academy of Sciences
  12. Control of Peripheral Nerve Myelination by the ß-Secretase BACE1 (2006)
    Michael Willem, Alistair N. Garratt et al. Science
  13. At the acidic edge: emerging functions for lysosomal membrane proteins (2003)
    Eeva‐Liisa Eskelinen, Yoshitaka Tanaka et al. Trends in Cell Biology
  14. LAMP proteins are required for fusion of lysosomes with phagosomes (2007)
    Kassidy K. Huynh, Eeva‐Liisa Eskelinen et al. The EMBO Journal

Immediate Impact

11 by Nobel laureates 66 from Science/Nature 130 standout
Sub-graph 1 of 17

Citing Papers

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13 intermediate papers

Works of Paul Säftig being referenced

Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy
2017
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice
1998 Standout
and 6 more

Author Peers

Author Last Decade Papers Cites
Paul Säftig 18628 11394 7785 327 38.5k
Lelio Orci 28531 7058 16045 576 51.9k
Dario R. Alessi 50134 6712 10045 308 64.7k
Robert E. Hammer 26926 7141 6512 287 52.2k
Shuh Narumiya 28576 8438 11905 550 59.8k
Guy S. Salvesen 36881 5593 5446 293 54.0k
Hediye Erdjument‐Bromage 52815 6603 7633 283 67.2k
Chu‐Xia Deng 30697 5201 4299 411 46.4k
Paul Tempst 61550 7665 8629 320 79.9k
Nancy A. Jenkins 35003 6482 7054 508 59.9k
John Blenis 38903 4630 6295 221 51.3k

All Works

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