Standout Papers

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia 2008 2026 2014 2020 1.4k
  1. Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia (2011)
    Christian M. Metallo, Paulo A. Gameiro et al. Nature
  2. Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles (2008)
    Ayush Verma, Oktay Uzun et al. Nature Materials
  3. Bio-inspired, bioengineered and biomimetic drug delivery carriers (2011)
    Jin‐Wook Yoo, Darrell J. Irvine et al. Nature Reviews Drug Discovery
  4. Structure-based programming of lymph-node targeting in molecular vaccines (2014)
    Haipeng Liu, Kelly D. Moynihan et al. Nature
  5. Enhancing cancer immunotherapy with nanomedicine (2020)
    Darrell J. Irvine, Eric L. Dane Nature reviews. Immunology
  6. Synthetic Nanoparticles for Vaccines and Immunotherapy (2015)
    Darrell J. Irvine, Melissa C. Hanson et al. Chemical Reviews
  7. Therapeutic cell engineering with surface-conjugated synthetic nanoparticles (2010)
    Matthias T. Stephan, James J. Moon et al. Nature Medicine
  8. Direct observation of ligand recognition by T cells (2002)
    Darrell J. Irvine, Marco A. Purbhoo et al. Nature
  9. Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery (2018)
    Li Tang, Yiran Zheng et al. Nature Biotechnology
  10. T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity (2017)
    Daniela Schmid, Chun Gwon Park et al. Nature Communications
  11. Enhanced CAR–T cell activity against solid tumors by vaccine boosting through the chimeric receptor (2019)
    Leyuan Ma, Tanmay Dichwalkar et al. Science
  12. Role of nanoscale antigen organization on B-cell activation probed using DNA origami (2020)
    Rémi Veneziano, Tyson J. Moyer et al. Nature Nanotechnology
  13. STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity (2022)
    Eric L. Dane, Alexis Belessiotis‐Richards et al. Nature Materials
  14. Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity (2023)
    Leyuan Ma, Duncan M. Morgan et al. Cell
  15. Human STING is a proton channel (2023)
    Bingxu Liu, Rebecca J. Carlson et al. Science
  16. LNP-RNA-engineered adipose stem cells for accelerated diabetic wound healing (2024)
    Yonger Xue, Yuebao Zhang et al. Nature Communications
  17. Linking vaccine adjuvant mechanisms of action to function (2025)
    Elana Ben‐Akiva, Tianyang Mao et al. Science Immunology

Immediate Impact

4 by Nobel laureates 31 from Science/Nature 104 standout
Sub-graph 1 of 17

Citing Papers

Principles and therapeutic applications of adaptive immunity
2024 Standout
SOX17 enables immune evasion of early colorectal adenomas and cancers
2024 StandoutNature
37 intermediate papers

Works of Darrell J. Irvine being referenced

Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer
2021
T cell killing does not require the formation of a stable mature immunological synapse
2004
and 20 more

Author Peers

Author Last Decade Papers Cites
Darrell J. Irvine 10666 9996 4645 7017 275 25.0k
Melody A. Swartz 6697 7772 9516 6641 185 23.3k
Leaf Huang 8911 30026 5645 9703 541 46.4k
Gert Storm 4153 12910 2718 9698 437 30.0k
Daniel G. Anderson 4591 26979 2382 10317 315 42.4k
Michael J. Mitchell 3217 7621 2545 5264 156 15.5k
Hideyoshi Harashima 3303 18244 1604 4479 562 25.0k
Carl G. Figdor 27159 13995 10373 3960 526 46.2k
Ronnie H. Fang 3823 9542 1187 12610 161 21.2k
Liangfang Zhang 4779 16537 1996 22961 309 41.8k
Zhen Gu 5649 13415 3689 17236 379 37.8k

All Works

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Rankless by CCL
2026