Carl G. Figdor

57.8k citations

528 papers · 46.9k indexed · 11 hit papers · h-index 112

Co-authors: Gosse J. Adema Yvette van Kooyk I. Jolanda M. de Vries J E de Vries Ruurd Torensma René de Waal Malefyt J S Abrams Alessandra Cambi
Topics: Immunotherapy and Immune Responses (298 papers)T-cell and B-cell Immunology (139 papers)Immune Cell Function and Interaction (104 papers)
Cited by: Immunology Immunology and Allergy Virology
Journals: Nature Cell Proceedings of the National Academy of Sciences
Partner nations: Netherlands United States Germany

In The Last Decade

Carl G. Figdor

528 papers receiving 46.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

1991 3.2k citations Carl G. Figdor et al. profile →
DC-SIGN, a Dendritic Cell–Specific HIV-1-Binding Protein that Enhances trans-Infection of T Cells

2000 1.9k citations Ruurd Torensma, Carl G. Figdor et al. profile →
Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

1991 1.7k citations John B.A.G. Haanen, Carl G. Figdor et al. profile →
Identification of DC-SIGN, a Novel Dendritic Cell–Specific ICAM-3 Receptor that Supports Primary Immune Responses

2000 1.4k citations Ruurd Torensma, Gosse J. Adema et al. profile →
Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

2013 1.0k citations Carl G. Figdor, Peter Friedl et al. The Journal of Cell Biology profile →
Dendritic cell immunotherapy: mapping the way

2004 778 citations Carl G. Figdor, I. Jolanda M. de Vries et al. profile →
C-type lectin receptors on dendritic cells and langerhans cells

2002 667 citations Carl G. Figdor, Yvette van Kooyk et al. profile →
Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy

2005 666 citations I. Jolanda M. de Vries, W. Joost Lesterhuis et al. profile →
Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting

2007 615 citations Paul J. Tacken, I. Jolanda M. de Vries et al. profile →
Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10.

1993 553 citations Carl G. Figdor et al. The Journal of Immunology profile →
The Dendritic Cell-Specific Adhesion Receptor DC-SIGN Internalizes Antigen for Presentation to T Cells

2002 514 citations Carl G. Figdor, Yvette van Kooyk et al. The Journal of Immunology profile →

Peers

Countries citing papers authored by Carl G. Figdor

Since Specialization

Citations

This map shows the geographic impact of Carl G. Figdor's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Carl G. Figdor with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Carl G. Figdor more than expected).

Fields of papers citing papers by Carl G. Figdor

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Carl G. Figdor. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Carl G. Figdor. The network helps show where Carl G. Figdor may publish in the future.

Co-authorship network of co-authors of Carl G. Figdor

This figure shows the co-authorship network connecting the top 25 collaborators of Carl G. Figdor. A scholar is included among the top collaborators of Carl G. Figdor based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Carl G. Figdor. Carl G. Figdor is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Paired primary and metastatic lesions of patients with ipilimumab-treated melanoma: high variation in lymphocyte infiltration and HLA-ABC expression whereas tumor mutational load is similar and correlates with clinical outcome 2022 ·Journal for ImmunoTherapy of Cancer ·Mark A.J. Gorris,Lieke L. van der Woude,Leonie I. Kroeze,Kalijn F. Bol,Kiek Verrijp,Avital L. Amir,(unknown),Johannes Textor,Carl G. Figdor,I. Jolanda M. de Vries	17
2	Industrial Scale Manufacturing and Downstream Processing of PLGA-Based Nanomedicines Suitable for Fully Continuous Operation 2022 ·Pharmaceutics ·(unknown),Alexander Bernhardt,(unknown),Eliézer Jäger,Silko Grimm,Andrea Engel,Martin Hrubý,Carl G. Figdor,Oya Tagit	28
3	Metabolic Screening of Cytotoxic T-cell Effector Function Reveals the Role of CRAC Channels in Regulating Lethal Hit Delivery 2021 ·Cancer Immunology Research ·Jeroen Slaats,Cindy E. Dieteren,Esther Wagena,Louis Wolf,Tonke K. Raaijmakers,Jeroen van der Laak,Carl G. Figdor,Bettina Weigelin,Peter Friedl	6
4	Cytotoxic T cells are able to efficiently eliminate cancer cells by additive cytotoxicity 2021 ·Nature Communications ·Bettina Weigelin,Annemieke Th. den Boer,Esther Wagena,Kelly Broen,Harry Dolstra,Rob J. de Boer,Carl G. Figdor,Johannes Textor,Peter Friedl	146
5	Collective invasion induced by an autocrine purinergic loop through connexin-43 hemichannels 2020 ·The Journal of Cell Biology ·Antoine Khalil,Olga Ilina,Angela Vasaturo,(unknown),Manon Vullings,(unknown),(unknown),Carl G. Figdor,Paul N. Span,Peter Friedl	28
6	Eight-Color Multiplex Immunohistochemistry for Simultaneous Detection of Multiple Immune Checkpoint Molecules within the Tumor Microenvironment 2017 ·The Journal of Immunology ·Mark A.J. Gorris,Altuna Halilović,Katrin Rabold,Anne van Duffelen,(unknown),(unknown),Inge M. N. Wortel,Johannes Textor,I. Jolanda M. de Vries,Carl G. Figdor	169
7	T-cell Landscape in a Primary Melanoma Predicts the Survival of Patients with Metastatic Disease after Their Treatment with Dendritic Cell Vaccines 2016 ·Cancer Research ·Angela Vasaturo,Altuna Halilović,Kalijn F. Bol,(unknown),Willeke A.M. Blokx,Cornelis J.A. Punt,Patricia J.T.A. Groenen,J. Han van Krieken,Johannes Textor,I. Jolanda M. de Vries,Carl G. Figdor	28
8	Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines 2016 ·Cancer Research ·Ghaith Bakdash,Sonja I. Buschow,Mark A.J. Gorris,Altuna Halilović,Stanleyson V. Hato,Annette E. Sköld,Gerty Schreibelt,Simone P. Sittig,Ruurd Torensma,Tjitske Duiveman‐de Boer,Christoph Schröder,Evelien Smits,Carl G. Figdor,I. Jolanda M. de Vries	90
9	Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients 2013 ·Cancer Research ·Jurjen Tel,Erik H.J.G. Aarntzen,Tetsuro Baba,Gerty Schreibelt,Barbara M. Schulte,Daniel Benítez‐Ribas,Otto C. Boerman,Sandra Croockewit,Wim J.G. Oyen,Michelle van Rossum,Gregor Winkels,Pierre G. Coulie,Cornelis J.A. Punt,Carl G. Figdor,I. Jolanda M. de Vries	289
10	Targeting of 111In-Labeled Dendritic Cell Human Vaccines Improved by Reducing Number of Cells 2013 ·Clinical Cancer Research ·Erik H.J.G. Aarntzen,Mangala Srinivas,F. Bonetto,Luis J. Cruz,Pauline Verdijk,Gerty Schreibelt,(unknown),W. Joost Lesterhuis,(unknown),(unknown),Gosse J. Adema,Arend Heerschap,Carl G. Figdor,Wim J.G. Oyen,I. Jolanda M. de Vries	49
11	Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell–Based Vaccination 2012 ·Cancer Research ·Erik H.J.G. Aarntzen,I. Jolanda M. de Vries,W. Joost Lesterhuis,Danita H. Schuurhuis,Joannes F.M. Jacobs,Kalijn F. Bol,Gerty Schreibelt,Roel Mus,Johannes H.W. de Wilt,John B.A.G. Haanen,Dirk Schadendorf,Alexandra Croockewit,Willeke A.M. Blokx,Michelle M. van Rossum,William W. Kwok,Gosse J. Adema,Cornelis J.A. Punt,Carl G. Figdor	131
12	Skin-Test Infiltrating Lymphocytes Early Predict Clinical Outcome of Dendritic Cell–Based Vaccination in Metastatic Melanoma 2012 ·Cancer Research ·Erik H.J.G. Aarntzen,Kalijn F. Bol,Gerty Schreibelt,Joannes F.M. Jacobs,W. Joost Lesterhuis,Michelle M. van Rossum,Gosse J. Adema,Carl G. Figdor,Cornelis J.A. Punt,I. Jolanda M. de Vries	42
13	Vaccination with mRNA-Electroporated Dendritic Cells Induces Robust Tumor Antigen-Specific CD4+ and CD8+ T Cells Responses in Stage III and IV Melanoma Patients 2012 ·Clinical Cancer Research ·Erik H.J.G. Aarntzen,Gerty Schreibelt,Kalijn F. Bol,W. Joost Lesterhuis,Alexandra Croockewit,Johannes H.W. de Wilt,Michelle M. van Rossum,Willeke A.M. Blokx,Joannes F.M. Jacobs,Tjitske Duiveman‐de Boer,Danita H. Schuurhuis,Roel Mus,Kris Thielemans,I. Jolanda M. de Vries,Carl G. Figdor,Cornelis J.A. Punt,Gosse J. Adema	80
14	Targeting Nanoparticles to Dendritic Cells for Immunotherapy 2012 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Luis J. Cruz,Paul J. Tacken,Félix Rueda,Joan Carles Domingo,Fernando Alberício,Carl G. Figdor	107
15	Route of Administration Modulates the Induction of Dendritic Cell Vaccine–Induced Antigen-Specific T Cells in Advanced Melanoma Patients 2011 ·Clinical Cancer Research ·W. Joost Lesterhuis,I. Jolanda M. de Vries,Gerty Schreibelt,Annechien J.A. Lambeck,Erik H.J.G. Aarntzen,Joannes F.M. Jacobs,Nicole M. Scharenborg,Mandy W.M.M. van de Rakt,Annemiek J. de Boer,Sandra Croockewit,Michelle M. van Rossum,Roel Mus,Wim J.G. Oyen,Otto C. Boerman,Sophie Lucas,Gosse J. Adema,Cornelis J.A. Punt,Carl G. Figdor	138
16	In vivo Colocalization of Antigen and CpG within Dendritic Cells Is Associated with the Efficacy of Cancer Immunotherapy 2008 ·Cancer Research ·Stefan Nierkens,Martijn H. den Brok,Roger P.M. Sutmuller,Oliver Grauer,Erik Bennink,Mary E. Morgan,Carl G. Figdor,Theo J. M. Ruers,Gosse J. Adema	47
17	PGE2-mediated podosome loss in dendritic cells is dependent on actomyosin contraction downstream of the RhoA–Rho-kinase axis 2008 ·Journal of Cell Science ·Suzanne F. G. van Helden,Machteld M. Oud,Ben Joosten,(unknown),Carl G. Figdor,Frank N. van Leeuwen	73
18	Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti–DC-SIGN antibody 2005 ·Blood ·Paul J. Tacken,I. Jolanda M. de Vries,Karlijn Gijzen,Ben Joosten,Dayang Wu,Russell P. Rother,Susan J. Faas,Cornelis J.A. Punt,Ruurd Torensma,Gosse J. Adema,Carl G. Figdor	219
19	Murine Hematopoietic Progenitor Cells With Colony-Forming or Radioprotective Capacity Lack Expression of the β2-Integrin LFA-1 1999 ·Blood ·Hans Pruijt,Yvette van Kooyk,Carl G. Figdor,Roel Willemze,Willem E. Fibbe	27
20	Constitutive up-regulation of integrin-mediated adhesion of tumor-infiltrating lymphocytes to osteoblasts and bone marrow-derived stromal cells. 1998 ·PubMed ·Yoshiya Tanaka,Shinichiro Mine,Takeshi Hanagiri,Toru Hiraga,I Morimoto,Carl G. Figdor,Yvette van Kooyk,Hiroki Ozawa,Tetsuya Nakamura,Kosei Yasumoto,S Eto	34

About Carl G. Figdor

Carl G. Figdor is a scholar working on Immunology, Immunology and Allergy and Oncology, having authored 528 papers that have together received 46.9k indexed citations. Recurring topics across this work include Immunotherapy and Immune Responses (298 papers), T-cell and B-cell Immunology (139 papers) and Immune Cell Function and Interaction (104 papers). The work is most often cited by research in Immunology (27.4k citations), Immunology and Allergy (5.2k citations) and Virology (2.2k citations). Carl G. Figdor has collaborated with scholars based in Netherlands, United States and Germany. Frequent co-authors include Gosse J. Adema, Yvette van Kooyk, I. Jolanda M. de Vries, J E de Vries, Ruurd Torensma, René de Waal Malefyt, J S Abrams, Alessandra Cambi, Sandra J. van Vliet and Paul J. Tacken. Their work appears in journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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