Michael J. Mitchell

23.1k total citations · 22 hit papers
164 papers, 16.8k citations indexed

About

Michael J. Mitchell is a scholar working on Molecular Biology, Oncology and Immunology. According to data from OpenAlex, Michael J. Mitchell has authored 164 papers receiving a total of 16.8k indexed citations (citations by other indexed papers that have themselves been cited), including 100 papers in Molecular Biology, 34 papers in Oncology and 34 papers in Immunology. Recurrent topics in Michael J. Mitchell's work include RNA Interference and Gene Delivery (74 papers), Advanced biosensing and bioanalysis techniques (35 papers) and Nanoparticle-Based Drug Delivery (19 papers). Michael J. Mitchell is often cited by papers focused on RNA Interference and Gene Delivery (74 papers), Advanced biosensing and bioanalysis techniques (35 papers) and Nanoparticle-Based Drug Delivery (19 papers). Michael J. Mitchell collaborates with scholars based in United States, China and Brazil. Michael J. Mitchell's co-authors include Róbert Langer, Margaret M. Billingsley, Rebecca M. Haley, Marissa E. Wechsler, Nicholas A. Peppas, Carl H. June, Rachel Riley, Michael R. King, Xuexiang Han and Drew Weissman and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Michael J. Mitchell

157 papers receiving 16.6k citations

Hit Papers

Engineering precision nanoparticles for drug delivery 2016 2026 2019 2022 2020 2019 2018 2016 2020 1000 2.0k 3.0k 4.0k 5.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Engineering precision nanoparticles for drug delivery
    2020 5.3k citations Michael J. Mitchell, Margaret M. Billingsley et al. profile →
  2. Delivery technologies for cancer immunotherapy
    2019 2.0k citations Rachel Riley, Carl H. June et al. profile →
  3. Advances in Biomaterials for Drug Delivery
    2018 657 citations Michael J. Mitchell et al. profile →
  4. Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy
    2016 582 citations Michael J. Mitchell et al. profile →
  5. Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering
    2020 453 citations Margaret M. Billingsley, Carl H. June et al. profile →
  6. An ionizable lipid toolbox for RNA delivery
    2021 415 citations Xuexiang Han, Kelsey L. Swingle et al. Nature Communications profile →
  7. Microfluidic formulation of nanoparticles for biomedical applications
    2021 274 citations Sarah J. Shepherd, David Issadore et al. profile →
  8. Nanomaterials for T-cell cancer immunotherapy
    2021 250 citations Ningqiang Gong, Neil C. Sheppard et al. profile →
  9. Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device
    2021 222 citations Sarah J. Shepherd, Claude C. Warzecha et al. profile →
  10. Ionizable lipid nanoparticles for in utero mRNA delivery
    2021 160 citations Rachel Riley, Meghana V. Kashyap et al. Science Advances profile →
  11. Nanoparticle protein corona: from structure and function to therapeutic targeting
    2023 147 citations Marshall S. Padilla, Kelsey L. Swingle et al. Lab on a Chip profile →
  12. Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines
    2023 147 citations Xuexiang Han, Mohamad‐Gabriel Alameh et al. profile →
  13. Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
    2022 124 citations Lulu Xue, Ningqiang Gong et al. Journal of the American Chemical Society profile →
  14. One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
    2021 123 citations Margaret M. Billingsley, Michael J. Mitchell et al. Journal of the American Chemical Society profile →
  15. Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
    2023 123 citations Xuexiang Han, Ningqiang Gong et al. Nature Communications profile →
  16. In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism
    2023 108 citations Margaret M. Billingsley, Ningqiang Gong et al. profile →
  17. Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
    2023 101 citations Kelsey L. Swingle, Hannah C. Safford et al. Journal of the American Chemical Society profile →
  18. Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells
    2022 90 citations Margaret M. Billingsley, Xuexiang Han et al. Journal of Controlled Release profile →
  19. High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models
    2024 83 citations Lulu Xue, Alex G. Hamilton et al. Nature Communications profile →
  20. Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
    2023 68 citations Sarah J. Shepherd, Xuexiang Han et al. Proceedings of the National Academy of Sciences profile →
  21. Ionizable Lipid Nanoparticles with Integrated Immune Checkpoint Inhibition for mRNA CAR T Cell Engineering
    2023 66 citations Alex G. Hamilton, Kelsey L. Swingle et al. profile →
  22. Enhancing in situ cancer vaccines using delivery technologies
    2024 64 citations Ningqiang Gong, Mohamad‐Gabriel Alameh et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Michael J. Mitchell United States 52 8.2k 5.5k 3.8k 3.4k 2.7k 164 16.8k
Dan Peer Israel 57 9.7k 1.2× 6.7k 1.2× 7.5k 2.0× 2.0k 0.6× 1.5k 0.6× 155 18.6k
James J. Moon United States 54 4.8k 0.6× 5.8k 1.0× 3.0k 0.8× 4.7k 1.4× 2.0k 0.7× 139 12.7k
Darrell J. Irvine United States 86 10.2k 1.2× 7.2k 1.3× 3.9k 1.0× 10.9k 3.2× 4.8k 1.8× 280 25.7k
Haifa Shen United States 46 5.6k 0.7× 4.4k 0.8× 4.4k 1.1× 1.4k 0.4× 1.2k 0.5× 125 11.6k
Robert J. Lee United States 66 8.7k 1.1× 3.7k 0.7× 5.0k 1.3× 1.0k 0.3× 1.5k 0.5× 319 16.0k
Na Zhang China 57 4.9k 0.6× 3.0k 0.5× 3.0k 0.8× 1.8k 0.5× 1.6k 0.6× 460 12.2k
James R. Baker United States 72 10.6k 1.3× 3.3k 0.6× 3.8k 1.0× 2.0k 0.6× 1.2k 0.5× 387 22.0k
Qiang Zhang China 76 9.4k 1.1× 6.1k 1.1× 7.5k 2.0× 1.6k 0.5× 1.9k 0.7× 402 19.2k
Kit S. Lam United States 68 10.8k 1.3× 3.7k 0.7× 3.1k 0.8× 1.2k 0.4× 2.1k 0.8× 404 18.9k
Weiwei Gao United States 75 8.2k 1.0× 11.4k 2.1× 5.7k 1.5× 3.2k 0.9× 1.0k 0.4× 215 20.4k

Countries citing papers authored by Michael J. Mitchell

Since Specialization
Citations

This map shows the geographic impact of Michael J. Mitchell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael J. Mitchell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael J. Mitchell more than expected).

Fields of papers citing papers by Michael J. Mitchell

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael J. Mitchell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael J. Mitchell. The network helps show where Michael J. Mitchell may publish in the future.

Co-authorship network of co-authors of Michael J. Mitchell

This figure shows the co-authorship network connecting the top 25 collaborators of Michael J. Mitchell. A scholar is included among the top collaborators of Michael J. Mitchell based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael J. Mitchell. Michael J. Mitchell is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Xue, Lulu, Xinhong Xiong, Gan Zhao, et al.. (2025). Multiarm-Assisted Design of Dendron-like Degradable Ionizable Lipids Facilitates Systemic mRNA Delivery to the Spleen. Journal of the American Chemical Society. 147(2). 1542–1552. 10 indexed citations
2.
Padilla, Marshall S., Sarah J. Shepherd, Martin Kurnik, et al.. (2025). Elucidating lipid nanoparticle properties and structure through biophysical analyses. Nature Biotechnology. 1 indexed citations
3.
Haley, Rebecca M., Marshall S. Padilla, Rakan El‐Mayta, et al.. (2025). Lipid Nanoparticles for In Vivo Lung Delivery of CRISPR-Cas9 Ribonucleoproteins Allow Gene Editing of Clinical Targets. ACS Nano. 19(14). 13790–13804. 6 indexed citations
4.
Wang, Jinjin, et al.. (2025). Drug-loaded bispecific T cell nanoengager overcomes T cell exhaustion for potent cancer immunotherapy. Proceedings of the National Academy of Sciences. 122(45). e2409564122–e2409564122.
5.
Haley, Rebecca M., Margaret M. Billingsley, Alexander Chan, et al.. (2024). Ionizable lipid nanoparticles for RAS protease delivery to inhibit cancer cell proliferation. Journal of Controlled Release. 370. 614–625. 6 indexed citations
6.
Hamilton, Alex G., Kelsey L. Swingle, Ajay S. Thatte, et al.. (2024). High-Throughput In Vivo Screening Identifies Differential Influences on mRNA Lipid Nanoparticle Immune Cell Delivery by Administration Route. ACS Nano. 18(25). 16151–16165. 25 indexed citations
7.
Hwang, Yoon‐Ho, Sarah J. Shepherd, Alvin J. Mukalel, et al.. (2024). Robust, Scalable Microfluidic Manufacturing of RNA–Lipid Nanoparticles Using Immobilized Antifouling Lubricant Coating. ACS Nano. 19(1). 1090–1102. 12 indexed citations
8.
Gong, Ningqiang, Xuexiang Han, Lulu Xue, et al.. (2024). Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager. Nature Biomedical Engineering. 8(5). 513–528. 14 indexed citations
9.
Palanki, Rohan, Emily L. Han, Kelsey L. Swingle, et al.. (2024). Optimized microfluidic formulation and organic excipients for improved lipid nanoparticle mediated genome editing. Lab on a Chip. 24(16). 3790–3801. 13 indexed citations
10.
Xue, Lulu, Alex G. Hamilton, Gan Zhao, et al.. (2024). High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models. Nature Communications. 15(1). 1884–1884. 83 indexed citations breakdown →
11.
Han, Xuexiang, Mohamad‐Gabriel Alameh, Ningqiang Gong, et al.. (2024). Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo. Nature Chemistry. 16(10). 1687–1697. 44 indexed citations
12.
Mrksich, Kaitlin, Marshall S. Padilla, & Michael J. Mitchell. (2024). Breaking the final barrier: Evolution of cationic and ionizable lipid structure in lipid nanoparticles to escape the endosome. Advanced Drug Delivery Reviews. 214. 115446–115446. 38 indexed citations
13.
Zhao, Gan, Lulu Xue, Christopher V. Cosgriff, et al.. (2024). Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation. Nature Communications. 15(1). 4235–4235. 18 indexed citations
14.
Yang, Fan, Duo Zhang, Rakan El‐Mayta, et al.. (2024). An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Science Advances. 10(9). eadj4678–eadj4678. 17 indexed citations
15.
Prazeres, Pedro Henrique Dias Moura, Pedro Augusto Carvalho Costa, Marshall S. Padilla, et al.. (2023). Delivery of Plasmid DNA by Ionizable Lipid Nanoparticles to Induce CAR Expression in T Cells. International Journal of Nanomedicine. Volume 18. 5891–5904. 23 indexed citations
16.
Swingle, Kelsey L., Adele S. Ricciardi, William H. Peranteau, & Michael J. Mitchell. (2023). Delivery technologies for women’s health applications. Nature Reviews Bioengineering. 1(6). 408–425. 32 indexed citations
17.
Riley, Rachel, Meghana V. Kashyap, Margaret M. Billingsley, et al.. (2021). Ionizable lipid nanoparticles for in utero mRNA delivery. Science Advances. 7(3). 160 indexed citations breakdown →
18.
Choueiri, Toni K., Michael B. Atkins, Ziad Bakouny, et al.. (2020). Summary From the First Kidney Cancer Research Summit, September 12–13, 2019: A Focus on Translational Research. JNCI Journal of the National Cancer Institute. 113(3). 234–243. 15 indexed citations
19.
Kohn, Julie C., Dennis W. Zhou, François Bordeleau, et al.. (2015). Cooperative Effects of Matrix Stiffness and Fluid Shear Stress on Endothelial Cell Behavior. Biophysical Journal. 108(3). 471–478. 131 indexed citations
20.
Haller, J O, Michael P. André, D Resnick, et al.. (1990). Detection of Thoracolumbar Vertebral Body Destruction with Lateral Spine Radiography Part I. Investigative Radiology. 25(5). 517–522. 9 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Dan Peer Breakdown of academic impact, for papers by James J. Moon Breakdown of academic impact, for papers by Darrell J. Irvine Breakdown of academic impact, for papers by Haifa Shen Breakdown of academic impact, for papers by Robert J. Lee Breakdown of academic impact, for papers by Na Zhang Breakdown of academic impact, for papers by James R. Baker Breakdown of academic impact, for papers by Qiang Zhang Breakdown of academic impact, for papers by Kit S. Lam Breakdown of academic impact, for papers by Weiwei Gao
Rankless by CCL
2026