Zhen Gu

48.0k total citations · 35 hit papers
386 papers, 39.4k citations indexed

About

Zhen Gu is a scholar working on Molecular Biology, Biomedical Engineering and Biomaterials. According to data from OpenAlex, Zhen Gu has authored 386 papers receiving a total of 39.4k indexed citations (citations by other indexed papers that have themselves been cited), including 154 papers in Molecular Biology, 150 papers in Biomedical Engineering and 83 papers in Biomaterials. Recurrent topics in Zhen Gu's work include Nanoplatforms for cancer theranostics (81 papers), Nanoparticle-Based Drug Delivery (71 papers) and RNA Interference and Gene Delivery (61 papers). Zhen Gu is often cited by papers focused on Nanoplatforms for cancer theranostics (81 papers), Nanoparticle-Based Drug Delivery (71 papers) and RNA Interference and Gene Delivery (61 papers). Zhen Gu collaborates with scholars based in United States, China and Singapore. Zhen Gu's co-authors include Quanyin Hu, Wujin Sun, Chao Wang, Jicheng Yu, Jinqiang Wang, Yanqi Ye, Yue Lü, Ran Mo, Guojun Chen and Tianyue Jiang and has published in prestigious journals such as Cell, Chemical Reviews and Proceedings of the National Academy of Sciences.

In The Last Decade

Zhen Gu

372 papers receiving 39.1k citations

Hit Papers

Bioresponsive materials 2013 2026 2017 2021 2016 2018 2019 2015 2016 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Bioresponsive materials
    2016 1.2k citations Yue Lü, Zhen Gu et al. profile →
  2. In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment
    2018 863 citations Guojun Chen, Quanyin Hu et al. profile →
  3. Enzyme-activatable polymer–drug conjugate augments tumour penetration and treatment efficacy
    2019 707 citations Jinqiang Wang, Zhen Gu et al. profile →
  4. Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery
    2015 688 citations Jicheng Yu, Yanqi Ye et al. Proceedings of the National Academy of Sciences profile →
  5. Enhanced Cancer Immunotherapy by Microneedle Patch-Assisted Delivery of Anti-PD1 Antibody
    2016 665 citations Yanqi Ye, Zhen Gu et al. profile →
  6. ATP-triggered anticancer drug delivery
    2014 616 citations Tianyue Jiang, Zhen Gu et al. profile →
  7. Enhanced Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic Reactive Oxygen Species
    2017 603 citations Jinqiang Wang, Zhen Gu et al. profile →
  8. Anticancer Platelet‐Mimicking Nanovehicles
    2015 559 citations Quanyin Hu, Wujin Sun et al. Advanced Materials profile →
  9. Self‐Assembled DNA Nanoclews for the Efficient Delivery of CRISPR–Cas9 for Genome Editing
    2015 543 citations Wujin Sun, Quanyin Hu et al. profile →
  10. Recent advances of cocktail chemotherapy by combination drug delivery systems
    2015 519 citations Quanyin Hu, Wujin Sun et al. profile →
  11. In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy
    2018 511 citations Jinqiang Wang, Di Wen et al. profile →
  12. Transformable liquid-metal nanomedicine
    2015 507 citations Yue Lü, Quanyin Hu et al. profile →
  13. Enzyme-responsive nanomaterials for controlled drug delivery
    2014 493 citations Quanyin Hu, Zhen Gu et al. profile →
  14. Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs
    2020 491 citations Jicheng Yu, Jinqiang Wang et al. Nature Biomedical Engineering profile →
  15. In situ activation of platelets with checkpoint inhibitors for post-surgical cancer immunotherapy
    2017 454 citations Wujin Sun, Yanqi Ye et al. Nature Biomedical Engineering profile →
  16. Light‐Activated Hypoxia‐Responsive Nanocarriers for Enhanced Anticancer Therapy
    2016 428 citations Jicheng Yu, Quanyin Hu et al. Advanced Materials profile →
  17. Advances in liquid metals for biomedical applications
    2018 418 citations Yue Lü, Guojun Chen et al. profile →
  18. Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells
    2019 400 citations Quanyin Hu, Guojun Chen et al. Advanced Materials profile →
  19. Injectable Nano-Network for Glucose-Mediated Insulin Delivery
    2013 388 citations Zhen Gu et al. ACS Nano profile →
  20. Advances in Antimicrobial Microneedle Patches for Combating Infections
    2020 366 citations Guojun Chen, Zhen Gu et al. Advanced Materials profile →
  21. Local generation of hydrogen for enhanced photothermal therapy
    2018 323 citations Zhen Gu et al. profile →
  22. Bacteria-Driven Hypoxia Targeting for Combined Biotherapy and Photothermal Therapy
    2018 321 citations Zhen Gu et al. ACS Nano profile →
  23. Tailoring Materials for Modulation of Macrophage Fate
    2021 298 citations Hongjun Li, Zhen Gu et al. Advanced Materials profile →
  24. Inhibition of post-surgery tumour recurrence via a hydrogel releasing CAR-T cells and anti-PDL1-conjugated platelets
    2021 292 citations Quanyin Hu, Hongjun Li et al. Nature Biomedical Engineering profile →
  25. Stretchable graphene–hydrogel interfaces for wearable and implantable bioelectronics
    2023 283 citations Yuqi Zhang, Jicheng Yu et al. profile →
  26. A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth
    2019 252 citations Di Wen, Jinqiang Wang et al. ACS Nano profile →
  27. Stimuli-responsive transdermal microneedle patches
    2021 219 citations Guojun Chen, Zhen Gu et al. profile →
  28. Scarless wound healing programmed by core-shell microneedles
    2023 218 citations Jiahuan You, Jicheng Yu et al. profile →
  29. Bioorthogonal catalytic patch
    2021 212 citations Hongjun Li, Zejun Wang et al. profile →
  30. ZnS@BSA Nanoclusters Potentiate Efficacy of Cancer Immunotherapy
    2021 184 citations Zhen Gu et al. Advanced Materials profile →
  31. Reformulating lipid nanoparticles for organ-targeted mRNA accumulation and translation
    2024 125 citations Tao Sheng, Zhen Gu et al. profile →
  32. Microneedle biomedical devices
    2023 118 citations Mengjia Zheng, Tao Sheng et al. Nature Reviews Bioengineering profile →
  33. Blue-ringed octopus-inspired microneedle patch for robust tissue surface adhesion and active injection drug delivery
    2023 115 citations Xinwei Wei, Zhen Gu et al. Science Advances profile →
  34. Inflammation‐Responsive Hydrogel Accelerates Diabetic Wound Healing through Immunoregulation and Enhanced Angiogenesis
    2024 48 citations Jiahuan You, Yuqi Zhang et al. profile →
  35. Coacervate vesicles assembled by liquid–liquid phase separation improve delivery of biopharmaceuticals
    2025 31 citations Ping Wen, Hanwei Huang et al. Nature Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Zhen Gu United States 108 17.7k 13.8k 10.3k 6.8k 5.8k 386 39.4k
Liangfang Zhang United States 113 23.6k 1.3× 16.9k 1.2× 14.2k 1.4× 2.7k 0.4× 4.9k 0.9× 315 43.2k
Kam W. Leong United States 118 17.5k 1.0× 15.8k 1.1× 14.9k 1.4× 3.1k 0.5× 3.0k 0.5× 659 48.5k
Véronique Préat Belgium 78 6.7k 0.4× 8.3k 0.6× 8.7k 0.8× 7.3k 1.1× 2.9k 0.5× 312 25.2k
Wim E. Hennink Netherlands 113 17.3k 1.0× 16.8k 1.2× 21.7k 2.1× 6.5k 1.0× 2.5k 0.4× 627 52.4k
Chao Wang China 92 23.5k 1.3× 10.0k 0.7× 8.6k 0.8× 1.5k 0.2× 6.3k 1.1× 373 37.2k
Xiangliang Yang China 85 11.4k 0.6× 7.2k 0.5× 6.4k 0.6× 3.4k 0.5× 1.9k 0.3× 510 25.5k
Gert Storm Netherlands 95 9.9k 0.6× 13.2k 1.0× 12.6k 1.2× 2.5k 0.4× 4.2k 0.7× 441 30.9k
Qian Chen China 97 16.9k 1.0× 13.0k 0.9× 6.5k 0.6× 810 0.1× 7.9k 1.4× 901 41.4k
Jun Wang China 106 16.6k 0.9× 18.1k 1.3× 13.6k 1.3× 1.3k 0.2× 6.1k 1.1× 1.1k 50.1k
Omid C. Farokhzad United States 114 28.7k 1.6× 24.9k 1.8× 29.4k 2.9× 5.0k 0.7× 4.6k 0.8× 224 62.8k

Countries citing papers authored by Zhen Gu

Since Specialization
Citations

This map shows the geographic impact of Zhen Gu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Zhen Gu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Zhen Gu more than expected).

Fields of papers citing papers by Zhen Gu

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Zhen Gu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Zhen Gu. The network helps show where Zhen Gu may publish in the future.

Co-authorship network of co-authors of Zhen Gu

This figure shows the co-authorship network connecting the top 25 collaborators of Zhen Gu. A scholar is included among the top collaborators of Zhen Gu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Zhen Gu. Zhen Gu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Yue, Ling, Yongsheng Pan, Wei Li, et al.. (2025). Predicting cognitive decline: Deep-learning reveals subtle brain changes in pre-MCI stage. The Journal of Prevention of Alzheimer s Disease. 12(5). 100079–100079. 2 indexed citations
2.
Wen, Ping, Hanwei Huang, Ruizhe Zhang, et al.. (2025). Coacervate vesicles assembled by liquid–liquid phase separation improve delivery of biopharmaceuticals. Nature Chemistry. 17(2). 279–288. 31 indexed citations breakdown →
3.
Cao, Jian, Jing Guo, Jiahe Wu, et al.. (2025). An engineering-reinforced extracellular vesicle–integrated hydrogel with an ROS-responsive release pattern mitigates spinal cord injury. Science Advances. 11(14). eads3398–eads3398. 14 indexed citations
4.
Zhang, Wentao, Yunlong Jiao, Ziru Zhang, et al.. (2024). Transdermal gene delivery. Journal of Controlled Release. 371. 516–529. 15 indexed citations
5.
Tian, Xue, Mingxing Feng, Xinwei Wei, et al.. (2024). In situ formed depot of elastin-like polypeptide-hirudin fusion protein for long-acting antithrombotic therapy. Proceedings of the National Academy of Sciences. 121(11). e2314349121–e2314349121. 7 indexed citations
6.
Tian, Xinyu, Yan Wang, Bin‐Bin Cui, et al.. (2024). Coin-sized, fully integrated, and minimally invasive continuous glucose monitoring system based on organic electrochemical transistors. Science Advances. 10(16). eadl1856–eadl1856. 56 indexed citations
7.
Luo, Dandan, Jiaqi Xu, Fuyao Liu, & Zhen Gu. (2024). Advances and Challenges in Cerebral Organoids Research. SHILAP Revista de lepidopterología. 4(5). 2 indexed citations
8.
You, Jiahuan, Jinpeng Han, Hao Wang, et al.. (2023). Ultrarapid‐Acting Microneedles for Immediate Delivery of Biotherapeutics. Advanced Materials. 35(45). e2304582–e2304582. 46 indexed citations
9.
Wu, Honghui, Xinchi Jiang, Juanjuan Zheng, et al.. (2023). Hybrid stem cell-derived bioresponsive vesicles for effective inflamed blood-brain barrier targeting delivery. Nano Today. 49. 101800–101800. 30 indexed citations
10.
Liu, Wei, Yanfang Wang, Anna R. Kahkoska, et al.. (2023). Week-long normoglycaemia in diabetic mice and minipigs via a subcutaneous dose of a glucose-responsive insulin complex. Nature Biomedical Engineering. 8(10). 1214–1225. 20 indexed citations
11.
Huang, Hanwei, Mengchi Sun, Ruizhe Zhang, et al.. (2023). Inhibition of Tumor Metastasis by Liquid‐Nitrogen‐Shocked Tumor Cells with Oncolytic Viruses Infection. Advanced Materials. 35(28). e2212210–e2212210. 36 indexed citations
12.
Zheng, Mengjia, et al.. (2023). Microneedle biomedical devices. Nature Reviews Bioengineering. 2(4). 324–342. 118 indexed citations breakdown →
13.
Chen, Guojun, Zhitong Chen, Di Wen, et al.. (2020). Transdermal cold atmospheric plasma-mediated immune checkpoint blockade therapy. Proceedings of the National Academy of Sciences. 117(7). 3687–3692. 205 indexed citations
14.
Wang, Zejun, Jinqiang Wang, Hongjun Li, et al.. (2020). Dual self-regulated delivery of insulin and glucagon by a hybrid patch. Proceedings of the National Academy of Sciences. 117(47). 29512–29517. 95 indexed citations
15.
Xu, Jianpei, Xiao-Qi Wang, Haoyuan Yin, et al.. (2019). Sequentially Site-Specific Delivery of Thrombolytics and Neuroprotectant for Enhanced Treatment of Ischemic Stroke. ACS Nano. 13(8). 8577–8588. 157 indexed citations
16.
Paul, Rajesh, Amanda C. Saville, Yanqi Ye, et al.. (2019). Extraction of Plant DNA by Microneedle Patch for Rapid Detection of Plant Diseases. ACS Nano. 13(6). 6540–6549. 138 indexed citations
17.
Khademhosseini, Ali, André E. Nel, Christopher J. DeSantis, et al.. (2019). Nanoscience and Nanotechnology at UCLA. ACS Nano. 13(6). 6127–6129. 1 indexed citations
18.
Lü, Yue, Wujin Sun, & Zhen Gu. (2014). Stimuli-responsive nanomaterials for therapeutic protein delivery. Journal of Controlled Release. 194. 1–19. 350 indexed citations
19.
Wang, Qun, Zhen Gu, Syed Asad Jamal, Michael S. Detamore, & Cory Berkland. (2013). Hybrid Hydroxyapatite Nanoparticle Colloidal Gels are Injectable Fillers for Bone Tissue Engineering. Tissue Engineering Part A. 19(23-24). 2586–2593. 67 indexed citations
20.
Zhao, Muxun, Anuradha Biswas, Biliang Hu, et al.. (2011). Redox-responsive nanocapsules for intracellular protein delivery. Biomaterials. 32(22). 5223–5230. 149 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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