Standout Papers

N6-methyladenosine-dependent regulation of messenger RNA stability 2011 2026 2016 2021 3.2k
  1. N6-methyladenosine-dependent regulation of messenger RNA stability (2013)
    Xiao Wang, Zhike Lu et al. Nature
  2. N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO (2011)
    Guifang Jia, Ye Fu et al. Nature Chemical Biology
  3. Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine (2011)
    Shinsuke Ito, Li Shen et al. Science
  4. N6-methyladenosine Modulates Messenger RNA Translation Efficiency (2015)
    Xiao Wang, Boxuan Zhao et al. Cell
  5. A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation (2013)
    Jianzhao Liu, Yanan Yue et al. Nature Chemical Biology
  6. Dynamic RNA Modifications in Gene Expression Regulation (2017)
    Ian A. Roundtree, Molly Evans et al. Cell
  7. Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA (2011)
    Yufei He, Zheng Li et al. Science
  8. Post-transcriptional gene regulation by mRNA modifications (2016)
    Boxuan Zhao, Ian A. Roundtree et al. Nature Reviews Molecular Cell Biology
  9. N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions (2015)
    Nian Liu, Qing Dai et al. Nature
  10. Gene expression regulation mediated through reversible m6A RNA methylation (2014)
    Ye Fu, Dan Dominissini et al. Nature Reviews Genetics
  11. YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA (2017)
    Hailing Shi, Xiao Wang et al. Cell Research
  12. Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers (2019)
    Hailing Shi, Jiangbo Wei et al. Molecular Cell
  13. m 6 A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program (2017)
    Sicong Zhang, Boxuan Zhao et al. Cancer Cell
  14. YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs (2017)
    Ian A. Roundtree, Guan‐Zheng Luo et al. eLife
  15. m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells (2017)
    Qi Cui, Hailing Shi et al. Cell Reports
  16. RNA modifications modulate gene expression during development (2018)
    Michaela Frye, Bryan T. Harada et al. Science
  17. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine (2010)
    Chun‐Xiao Song, Keith E. Szulwach et al. Nature Biotechnology
  18. Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome (2012)
    Miao Yu, Gary C. Hon et al. Cell
  19. Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis (2017)
    Phillip J. Hsu, Yunfei Zhu et al. Cell Research
  20. The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA (2016)
    Dan Dominissini, Sigrid Nachtergaele et al. Nature
  21. VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation (2018)
    Yanan Yue, Jun Liu et al. Cell Discovery
  22. Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells (2019)
    Dali Han, Jun Liu et al. Nature
  23. RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation (2015)
    Yanan Yue, Jianzhao Liu et al. Genes & Development
  24. Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal (2018)
    Jing Wen, Ruitu Lv et al. Molecular Cell
  25. RNA m6A methylation regulates the ultraviolet-induced DNA damage response (2017)
    Yang Xiang, Benoît Laurent et al. Nature
  26. 5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging (2011)
    Keith E. Szulwach, Xuekun Li et al. Nature Neuroscience
  27. m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer (2018)
    Jun Liu, Mark A. Eckert et al. Nature Cell Biology
  28. Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm (2018)
    Jiangbo Wei, Fange Liu et al. Molecular Cell
  29. Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain (2014)
    Chao Xu, Xiao Wang et al. Nature Chemical Biology
  30. m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade (2019)
    Seungwon Yang, Jiangbo Wei et al. Nature Communications
  31. Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation (2017)
    Ki‐Jun Yoon, Francisca Rojas et al. Cell
  32. DNA Methylation on N6-Adenine in C. elegans (2015)
    Eric Lieberman Greer, Andrés Blanco et al. Cell
  33. N 6 -methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription (2020)
    Jun Liu, Xiaoyang Dou et al. Science
  34. m 6 A RNA methylation: from mechanisms to therapeutic potential (2021)
    P. Cody He, Chuan He The EMBO Journal
  35. Selective fluorescent probes for live-cell monitoring of sulphide (2011)
    Yong Qian, Jason Karpus et al. Nature Communications
  36. N6-Methyladenine DNA Modification in Drosophila (2015)
    Guoqiang Zhang, Hua Huang et al. Cell
  37. ALKBH1-Mediated tRNA Demethylation Regulates Translation (2016)
    Fange Liu, Wesley C. Clark et al. Cell
  38. m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition (2017)
    Boxuan Zhao, Xiao Wang et al. Nature
  39. N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis (2017)
    Raghu Ram Edupuganti, Simon Geiger et al. Nature Structural & Molecular Biology
  40. Programming and Inheritance of Parental DNA Methylomes in Mammals (2014)
    Lu Wang, Jun Zhang et al. Cell
  41. Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA (2019)
    Lisheng Zhang, Chang Liu et al. Molecular Cell
  42. YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis (2020)
    Guoqiang Chang, Lei Shi et al. Cancer Cell
  43. EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma (2021)
    Runping Fang, Xin Chen et al. Nature Communications
  44. m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome (2022)
    Lulu Hu, Shun Liu et al. Nature Biotechnology
  45. Quantitative sequencing using BID-seq uncovers abundant pseudouridines in mammalian mRNA at base resolution (2022)
    Qing Dai, Lisheng Zhang et al. Nature Biotechnology
  46. Exon architecture controls mRNA m 6 A suppression and gene expression (2023)
    P. Cody He, Jiangbo Wei et al. Science
  47. YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8+ T cells (2023)
    Shoubao Ma, Baofa Sun et al. Nature Immunology
  48. Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination (2023)
    Yu‐Lan Xiao, Shun Liu et al. Nature Biotechnology
  49. Ultrafast bisulfite sequencing detection of 5-methylcytosine in DNA and RNA (2024)
    Qing Dai, Chang Ye et al. Nature Biotechnology

Immediate Impact

10 by Nobel laureates 70 from Science/Nature 134 standout
Sub-graph 1 of 14

Citing Papers

Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
The role of retrotransposable elements in ageing and age-associated diseases
2021 StandoutNature

Works of Chuan He being referenced

Dynamics of Human and Viral RNA Methylation during Zika Virus Infection
2016
N6-Methyladenine DNA Modification in Drosophila
2015 Standout
and 1 more

Author Peers

Author Last Decade Papers Cites
Chuan He 68343 25021 4514 7326 533 75.1k
Tomas Lindahl 31911 8063 5089 852 360 42.1k
Stuart L. Schreiber 65808 9195 4637 850 589 90.4k
Robert Huber 46461 6236 4993 1081 596 66.0k
Peter G. Schultz 50248 2107 5890 2734 690 72.2k
Stephen P. Jackson 55777 9693 7204 621 346 65.3k
Robert H. Crabtree 23640 2859 2668 4088 725 79.1k
Navdeep S. Chandel 32954 15615 2847 434 294 55.6k
J. Silvio Gutkind 33353 5723 2879 843 575 51.5k
Qing Dai 27261 9411 1980 2411 157 29.3k
Christopher J. Schofield 27552 15065 4365 323 791 44.6k

All Works

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