Paul J. Spiess

10.4k total citations · 5 hit papers
40 papers, 8.4k citations indexed

About

Paul J. Spiess is a scholar working on Immunology, Oncology and Molecular Biology. According to data from OpenAlex, Paul J. Spiess has authored 40 papers receiving a total of 8.4k indexed citations (citations by other indexed papers that have themselves been cited), including 35 papers in Immunology, 20 papers in Oncology and 9 papers in Molecular Biology. Recurrent topics in Paul J. Spiess's work include Immunotherapy and Immune Responses (31 papers), CAR-T cell therapy research (17 papers) and Immune Cell Function and Interaction (16 papers). Paul J. Spiess is often cited by papers focused on Immunotherapy and Immune Responses (31 papers), CAR-T cell therapy research (17 papers) and Immune Cell Function and Interaction (16 papers). Paul J. Spiess collaborates with scholars based in United States, Malaysia and Australia. Paul J. Spiess's co-authors include Steven A. Rosenberg, René Lafrenière, Nicholas P. Restifo, S A Rosenberg, James J. Mulé, Susan Schwarz, S. Schwarz, Paul A. Antony, Christopher A. Klebanoff and Douglas C. Palmer and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Nature Medicine.

In The Last Decade

Paul J. Spiess

40 papers receiving 8.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

1998 1.5k citations Steven A. Rosenberg, James Chih‐Hsin Yang et al. Nature Medicine profile →
A New Approach to the Adoptive Immunotherapy of Cancer with Tumor-Infiltrating Lymphocytes

1986 1.4k citations Steven A. Rosenberg, Paul J. Spiess et al. profile →
Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8 + T cells

2005 812 citations Luca Gattinoni, Steven E. Finkelstein et al. The Journal of Experimental Medicine profile →
Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells

2003 751 citations Marc R. Theoret, Steven E. Finkelstein et al. The Journal of Experimental Medicine profile →
Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2.

1985 593 citations S A Rosenberg, James J. Mulé et al. The Journal of Experimental Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Paul J. Spiess United States	32	6.8k	4.8k	2.1k	1.2k	618	40	8.4k
John R. Yannelli United States	34	5.5k 0.8×	3.6k 0.8×	2.2k 1.0×	793 0.6×	597 1.0×	74	7.3k
Michael J. Mastrangelo United States	46	3.1k 0.4×	3.2k 0.7×	1.9k 0.9×	739 0.6×	592 1.0×	190	6.3k
Kathleen E. Morton United States	17	6.2k 0.9×	6.0k 1.3×	1.9k 0.9×	1.4k 1.1×	300 0.5×	19	8.8k
Willem W. Overwijk United States	49	7.1k 1.0×	4.9k 1.0×	2.7k 1.3×	931 0.8×	390 0.6×	112	9.6k
Paul Aebersold United States	17	2.7k 0.4×	2.8k 0.6×	1.6k 0.7×	1.3k 1.1×	316 0.5×	29	4.9k
Hideaki Tahara Japan	51	5.1k 0.7×	3.5k 0.7×	3.6k 1.7×	1.9k 1.5×	280 0.5×	172	9.0k
Emma Di Carlo Italy	45	4.0k 0.6×	2.9k 0.6×	1.8k 0.8×	616 0.5×	715 1.2×	125	6.1k
Sharon Mavroukakis United States	21	7.0k 1.0×	7.6k 1.6×	2.3k 1.1×	1.9k 1.5×	454 0.7×	36	10.5k
Timothy M. Clay United States	41	3.2k 0.5×	2.2k 0.5×	2.6k 1.2×	796 0.6×	491 0.8×	97	5.9k
Michael I. Nishimura United States	44	4.6k 0.7×	3.2k 0.7×	1.8k 0.9×	885 0.7×	369 0.6×	135	6.5k

Countries citing papers authored by Paul J. Spiess

Since Specialization

Citations

This map shows the geographic impact of Paul J. Spiess's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul J. Spiess with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul J. Spiess more than expected).

Fields of papers citing papers by Paul J. Spiess

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul J. Spiess. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul J. Spiess. The network helps show where Paul J. Spiess may publish in the future.

Co-authorship network of co-authors of Paul J. Spiess

This figure shows the co-authorship network connecting the top 25 collaborators of Paul J. Spiess. A scholar is included among the top collaborators of Paul J. Spiess based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul J. Spiess. Paul J. Spiess is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Guo, Zong Sheng, Julie A. Hong, Kari R. Irvine, et al.. (2006). De novoInduction of a Cancer/Testis Antigen by 5-Aza-2′-Deoxycytidine Augments Adoptive Immunotherapy in a Murine Tumor Model. Cancer Research. 66(2). 1105–1113. 120 indexed citations

Gattinoni, Luca, Steven E. Finkelstein, Christopher A. Klebanoff, et al.. (2005). Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8 + T cells. The Journal of Experimental Medicine. 202(7). 907–912. 812 indexed citations breakdown →

Klebanoff, Christopher A., Steven E. Finkelstein, Deborah R. Surman, et al.. (2004). IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8 ⁺ T Cells. Proceedings of the National Academy of Sciences. 101(7). 1969–1974. 481 indexed citations

Weinreich, David M., Dina M. Elaraj, Markus Puhlmann, et al.. (2003). Effect of interleukin 1 receptor antagonist gene transduction on human melanoma xenografts in nude mice.. PubMed. 63(18). 5957–61. 42 indexed citations

Pérez‐Díez, Ainhoa, Paul J. Spiess, Nicholas P. Restifo, Polly Matzinger, & Francesco M. Marincola. (2002). Intensity of the Vaccine-Elicited Immune Response Determines Tumor Clearance. The Journal of Immunology. 168(1). 338–347. 68 indexed citations

Rosenberg, Steven A., Paul J. Spiess, & David E. Kleiner. (2002). Antitumor Effects in Mice of the Intravenous Injection of Attenuated Salmonella Typhimurium. Journal of Immunotherapy. 25(3). 218–225. 66 indexed citations

Rosenberg, Steven A., James Chih‐Hsin Yang, Douglas J. Schwartzentruber, et al.. (1999). Impact of Cytokine Administration on the Generation of Antitumor Reactivity in Patients with Metastatic Melanoma Receiving a Peptide Vaccine. The Journal of Immunology. 163(3). 1690–1695. 141 indexed citations

Rosenberg, Steven A., James Chih‐Hsin Yang, Douglas J. Schwartzentruber, et al.. (1998). Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nature Medicine. 4(3). 321–327. 1480 indexed citations breakdown →

Shilyansky, Joel, James Chih‐Hsin Yang, Mary Custer, et al.. (1997). Identification of a T-Cell Receptor from a Therapeutic Murine T-Cell Clone. Journal of Immunotherapy. 20(4). 247–225. 8 indexed citations

10.

Zhai, Yougang, James Chih‐Hsin Yang, Yasuhiko Kawakami, et al.. (1996). Antigen-specific tumor vaccines. Development and characterization of recombinant adenoviruses encoding MART1 or gp100 for cancer therapy. The Journal of Immunology. 156(2). 700–710. 133 indexed citations

11.

Minev, Boris, et al.. (1994). Insertion signal sequence fused to minimal peptides elicits specific CD8+ T-cell responses and prolongs survival of thymoma-bearing mice.. PubMed. 54(15). 4155–61. 76 indexed citations

12.

Barth, Richard J., James J. Mulé, Paul J. Spiess, & Steven A. Rosenberg. (1991). Interferon gamma and tumor necrosis factor have a role in tumor regressions mediated by murine CD8+ tumor-infiltrating lymphocytes.. The Journal of Experimental Medicine. 173(3). 647–658. 348 indexed citations

13.

Spiess, Paul J., et al.. (1990). Synergistic antitumor activity of tumor-infiltrating lymphocytes, interleukin 2, and local tumor irradiation. Studies on the mechanism of action.. The Journal of Experimental Medicine. 171(1). 249–263. 97 indexed citations

14.

Rosenberg, S A, S. Schwarz, & Paul J. Spiess. (1988). Combination Immunotherapy for Cancer:Synergistic Antitumor Interactions of Interleukin-2, Alfa Interferon, and Tumor-Infiltrating Lymphocytes. JNCI Journal of the National Cancer Institute. 80(17). 1393–1397. 106 indexed citations

15.

Rosenberg, Steven A., Paul J. Spiess, & Susan Schwarz. (1983). IN VIVO ADMINISTRATION OF INTERLEUKIN-2 ENHANCES SPECIFIC ALLOIMMUNE RESPONSES. Transplantation. 35(6). 631–633. 50 indexed citations

16.

Eberlein, Timothy J., Maury Rosenstein, Paul J. Spiess, & Steven A. Rosenberg. (1982). Generation of Long-Term T-Lymphoid Cell Lines With Specific Cytotoxic Reactivity for a Syngeneic Murine Lymphoma<xref ref-type="fn" rid="FN2">2</xref>. JNCI Journal of the National Cancer Institute. 69(1). 109–16. 8 indexed citations

17.

Rosenberg, Steven A., Susan Schwarz, & Paul J. Spiess. (1978). In vitro growth of murine T cells. II. Growth of in vitro sensitized cells cytotoxic for alloantigens.. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 121(5). 1951–5. 42 indexed citations

18.

Rosenberg, Steven A., Susan Schwarz, & Paul J. Spiess. (1978). In Vitro Growth of Murine T Cells. The Journal of Immunology. 121(5). 1951–1955. 22 indexed citations

19.

Rosenberg, Steven A., Paul J. Spiess, & Susan Schwarz. (1978). In Vitro Growth of Murine T Cells. The Journal of Immunology. 121(5). 1946–1950. 33 indexed citations

20.

Spiess, Paul J., et al.. (1973). REDUCTION OF PREEXISTING TRANSPLANTATION IMMUNITY BY SPECIFIC PREGNANCY. Transplantation. 15(4). 413–415. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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