Zhike Lu

38.0k total citations · 17 hit papers
54 papers, 23.7k citations indexed

About

Zhike Lu is a scholar working on Molecular Biology, Cancer Research and Electrical and Electronic Engineering. According to data from OpenAlex, Zhike Lu has authored 54 papers receiving a total of 23.7k indexed citations (citations by other indexed papers that have themselves been cited), including 51 papers in Molecular Biology, 19 papers in Cancer Research and 6 papers in Electrical and Electronic Engineering. Recurrent topics in Zhike Lu's work include RNA modifications and cancer (37 papers), Cancer-related molecular mechanisms research (19 papers) and Cancer-related gene regulation (15 papers). Zhike Lu is often cited by papers focused on RNA modifications and cancer (37 papers), Cancer-related molecular mechanisms research (19 papers) and Cancer-related gene regulation (15 papers). Zhike Lu collaborates with scholars based in United States, China and France. Zhike Lu's co-authors include Chuan He, Xiao Wang, Dali Han, Hailing Shi, Boxuan Zhao, Guifang Jia, Qing Dai, Honghui Ma, Ye Fu and Yanan Yue and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Zhike Lu

53 papers receiving 23.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

N6-methyladenosine-dependent regulation of messenger RNA stability

2013 3.3k citations Xiao Wang, Zhike Lu et al. profile →
N6-methyladenosine Modulates Messenger RNA Translation Efficiency

2015 2.6k citations Xiao Wang, Boxuan Zhao et al. Cell profile →
A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

2013 2.5k citations Jianzhao Liu, Xiao Wang et al. profile →
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA

2017 1.4k citations Hailing Shi, Xiao Wang et al. Cell Research profile →
Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

2011 1.4k citations Minjia Tan, Hao Luo et al. Cell profile →
m 6 A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program

2017 1.1k citations Boxuan Zhao, Zhike Lu et al. profile →
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

2017 967 citations Hailing Shi, Zhike Lu et al. Cell Reports profile →
Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis

2017 804 citations Phillip J. Hsu, Honghui Ma et al. Cell Research profile →
RNA m6A methylation regulates the ultraviolet-induced DNA damage response

2017 683 citations Zhike Lu, Chuan He et al. profile →
Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm

2018 606 citations Jiangbo Wei, Fange Liu et al. Molecular Cell profile →
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer

2018 603 citations Jun Liu, Mark A. Eckert et al. Nature Cell Biology profile →
The First Identification of Lysine Malonylation Substrates and Its Regulatory Enzyme

2011 597 citations Chao Peng, Zhike Lu et al. Molecular & Cellular Proteomics profile →
Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain

2014 568 citations Xiao Wang, Zhike Lu et al. profile →
m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade

2019 565 citations Jiangbo Wei, Zhike Lu et al. Nature Communications profile →
m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition

2017 430 citations Boxuan Zhao, Xiao Wang et al. profile →
N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis

2017 427 citations Raghu Ram Edupuganti, Simon Geiger et al. Nature Structural & Molecular Biology profile →
The m ⁶ A Reader ECT2 Controls Trichome Morphology by Affecting mRNA Stability in Arabidopsis

2018 292 citations Lian-Huan Wei, Peizhe Song et al. The Plant Cell profile →

Peers

Countries citing papers authored by Zhike Lu

Since Specialization

Citations

This map shows the geographic impact of Zhike Lu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Zhike Lu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Zhike Lu more than expected).

Fields of papers citing papers by Zhike Lu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Zhike Lu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Zhike Lu. The network helps show where Zhike Lu may publish in the future.

Co-authorship network of co-authors of Zhike Lu

This figure shows the co-authorship network connecting the top 25 collaborators of Zhike Lu. A scholar is included among the top collaborators of Zhike Lu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Zhike Lu. Zhike Lu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The Transpeptidase Sortase A Binds Nucleic Acids and Mediates Mammalian Cell Labeling 2024 ·Advanced Science ·Yingzheng Liu, Zhike Lu, Panfeng Wu, (unknown), (unknown), Ke Ni, Lijia Ma	2
2	Machine learning-based prediction models to guide the selection of Cas9 variants for efficient gene editing 2024 ·Cell Reports ·Jianbo Li, Panfeng Wu, (unknown), (unknown), Zhike Lu, Jianfeng Yan, Heng Zhang, Yangfan Zhou, Rong Liu, Hui Chen, Lijia Ma, Mengcheng Luo	6
3	The RNA m6A demethylase ALKBH5 drives emergency granulopoiesis and neutrophil mobilization by upregulating G-CSFR expression 2023 ·Cellular and Molecular Immunology ·Yang Liu, Renjie Song, Zhike Lu, Lu Zhao, (unknown), Yini Li, Xuetao Cao	26
4	Deep sampling of gRNA in the human genome and deep-learning-informed prediction of gRNA activities 2023 ·Cell Discovery ·(unknown), Jianfeng Yan, Zhike Lu, Yangfan Zhou, (unknown), Tingting Cui, Yini Li, Hui Chen, Lijia Ma	16
5	m6A demethylase ALKBH5 is required for antibacterial innate defense by intrinsic motivation of neutrophil migration 2022 ·Signal Transduction and Targeted Therapy ·Yang Liu, Renjie Song, Lu Zhao, Zhike Lu, Yini Li, (unknown), (unknown), Yang Jiang, Yamei Niu, Xuetao Cao	58
6	New Chromatin Run-On Reaction Enables Global Mapping of Active RNA Polymerase Locations in an Enrichment-free Manner 2022 ·ACS Chemical Biology ·Minsong Gao, Yini Li, Xiao Ou Shu, Pengfei Dai, Jie Cao, (unknown), (unknown), (unknown), Fengqin Wang, Zhike Lu, Fei‐Long Meng, Xin‐Hua Feng, Lijia Ma, Jianzhao Liu	2
7	Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus 2019 ·Nature Communications ·Miaoge Xue, Boxuan Zhao, Zijie Zhang, Mijia Lu, Olivia Harder, Phylip Chen, Zhike Lu, Anzhong Li, Yuanmei Ma, Yunsheng Xu, Xueya Liang, Jiyong Zhou, Stefan Niewiesk, Mark E. Peeples, Chuan He, Jiànróng Lǐ	77
8	YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma 2019 ·Molecular Cancer ·Jiajie Hou, He Zhang, Jun Liu, Zhenjun Zhao, Jianye Wang, Zhike Lu, Bian Hu, Jiankui Zhou, Zhicong Zhao, Mingxuan Feng, Haiyan Zhang, Bin Shen, Xingxu Huang, Beicheng Sun, Chuan He, Qiang Xia	268
9	N ⁶ -methyladenosine RNA modification–mediated cellular metabolism rewiring inhibits viral replication 2019 ·Science ·Yang Liu, (unknown), Zhike Lu, Yang Jiang, Panpan Li, Lun Liu, Henan Xu, Yamei Niu, Xuetao Cao	171
10	The m ⁶ A Reader ECT2 Controls Trichome Morphology by Affecting mRNA Stability in Arabidopsis breakdown → 2018 ·The Plant Cell ·Lian-Huan Wei, Peizhe Song, Ye Wang, Zhike Lu, Qian Tang, Qiong Yu, Yu Xiao, Xiao Zhang, Hong‐Chao Duan, Guifang Jia	292
11	m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer breakdown → 2018 ·Nature Cell Biology ·Jun Liu, Mark A. Eckert, Bryan T. Harada, Song‐Mei Liu, Zhike Lu, Kang‐Kang Yu, Samantha M. Tienda, Agnieszka Chryplewicz, Allen Zhu, Ying Yang, Jingtao Huang, Shaomin Chen, Zhigao Xu, Xiaohua Leng, Xuechen Yu, Jie Cao, (unknown), Jianzhao Liu, Ernst Lengyel, Chuan He	603
12	Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm breakdown → 2018 ·Molecular Cell ·Jiangbo Wei, Fange Liu, Zhike Lu, Qili Fei, Yuxi Ai, P. Cody He, Hailing Shi, Xiaolong Cui, Rui Su, Arne Klungland, Guifang Jia, Jianjun Chen, Chuan He	606
13	Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning 2018 ·Neuron ·Jessica L. Koranda, (unknown), Hailing Shi, Meera Patel, (unknown), (unknown), Kai Chen, Zhike Lu, Yangtian Yi, Wanhao Chi, Chuan He, Xiaoxi Zhuang	109
14	ALKBH10B Is an RNA N ⁶ -Methyladenosine Demethylase Affecting Arabidopsis Floral Transition 2017 ·The Plant Cell ·Hong‐Chao Duan, Lian-Huan Wei, Chi Zhang, Ye Wang, Lin Chen, Zhike Lu, Peng R. Chen, Chuan He, Guifang Jia	307
15	N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis breakdown → 2017 ·Nature Structural & Molecular Biology ·Raghu Ram Edupuganti, Simon Geiger, Rik G.H. Lindeboom, Hailing Shi, Phillip J. Hsu, Zhike Lu, Shuang-Yin Wang, Marijke Baltissen, Pascal W.T.C. Jansen, Martin Rossa, Markus Müller, Hendrik G. Stunnenberg, Chuan He, Thomas Carell, Michiel Vermeulen	427
16	YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA breakdown → 2017 ·Cell Research ·Hailing Shi, Xiao Wang, Zhike Lu, Boxuan Zhao, Honghui Ma, Phillip J. Hsu, Chang Liu, Chuan He	1392
17	Dynamics of Human and Viral RNA Methylation during Zika Virus Infection 2016 ·Cell Host & Microbe ·Gianluigi Lichinchi, Boxuan Zhao, Yinga Wu, Zhike Lu, Yue Qin, Chuan He, Tariq M. Rana	306
18	Quantitative Acetylome Analysis Reveals the Roles of SIRT1 in Regulating Diverse Substrates and Cellular Pathways 2012 ·Molecular & Cellular Proteomics ·Yue Chen, Wenhui Zhao, Jeong Soo Yang, Zhongyi Cheng, Hao Luo, Zhike Lu, Minjia Tan, Wei Gu, Yingming Zhao	178
19	Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification breakdown → 2011 ·Cell ·Minjia Tan, Hao Luo, Sangkyu Lee, Fulai Jin, Jeong Soo Yang, Emilie Montellier, Thierry Buchou, Zhongyi Cheng, Sophie Rousseaux, Nisha Rajagopal, Zhike Lu, Zhen Ye, Qin Zhu, Joanna Wysocka, Yang Ye, Saadi Khochbin, Bing Ren, Yingming Zhao	1385
20	The First Identification of Lysine Malonylation Substrates and Its Regulatory Enzyme breakdown → 2011 ·Molecular & Cellular Proteomics ·Chao Peng, Zhike Lu, Zhongyu Xie, Zhongyi Cheng, Yue Chen, Minjia Tan, Hao Luo, Yi Zhang, Wendy He, Ke Yang, Bernadette Zwaans, Daniel X. Tishkoff, Linh Ho, David B. Lombard, Tong‐Chuan He, Junbiao Dai, Eric Verdin, Yang Ye, Yingming Zhao	597

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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