Zhike Lu

38.0k total citations · 17 hit papers
54 papers, 23.7k citations indexed

About

Zhike Lu is a scholar working on Molecular Biology, Cancer Research and Electrical and Electronic Engineering. According to data from OpenAlex, Zhike Lu has authored 54 papers receiving a total of 23.7k indexed citations (citations by other indexed papers that have themselves been cited), including 51 papers in Molecular Biology, 19 papers in Cancer Research and 6 papers in Electrical and Electronic Engineering. Recurrent topics in Zhike Lu's work include RNA modifications and cancer (37 papers), Cancer-related molecular mechanisms research (19 papers) and Cancer-related gene regulation (15 papers). Zhike Lu is often cited by papers focused on RNA modifications and cancer (37 papers), Cancer-related molecular mechanisms research (19 papers) and Cancer-related gene regulation (15 papers). Zhike Lu collaborates with scholars based in United States, China and France. Zhike Lu's co-authors include Chuan He, Xiao Wang, Dali Han, Hailing Shi, Boxuan Zhao, Guifang Jia, Qing Dai, Honghui Ma, Ye Fu and Yanan Yue and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Zhike Lu

53 papers receiving 23.6k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

N6-methyladenosine-dependent regulation of messenger RNA stability

2013 3.3k citations Xiao Wang, Zhike Lu et al. profile →
N6-methyladenosine Modulates Messenger RNA Translation Efficiency

2015 2.6k citations Xiao Wang, Boxuan Zhao et al. Cell profile →
A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

2013 2.5k citations Jianzhao Liu, Yanan Yue et al. Nature Chemical Biology profile →
YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA

2017 1.4k citations Hailing Shi, Xiao Wang et al. Cell Research profile →
Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

2011 1.4k citations Minjia Tan, Hao Luo et al. Cell profile →
m 6 A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program

2017 1.1k citations Boxuan Zhao, Zhike Lu et al. profile →
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

2017 967 citations Hailing Shi, Zhike Lu et al. Cell Reports profile →
Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis

2017 804 citations Phillip J. Hsu, Honghui Ma et al. Cell Research profile →
RNA m6A methylation regulates the ultraviolet-induced DNA damage response

2017 683 citations Zhike Lu, Chuan He et al. profile →
Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm

2018 606 citations Zhike Lu, Hailing Shi et al. profile →
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer

2018 603 citations Jun Liu, Mark A. Eckert et al. Nature Cell Biology profile →
The First Identification of Lysine Malonylation Substrates and Its Regulatory Enzyme

2011 597 citations Zhike Lu, Zhongyi Cheng et al. profile →
Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain

2014 568 citations Xiao Wang, Zhike Lu et al. Nature Chemical Biology profile →
m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade

2019 565 citations Zhike Lu, Chuan He et al. Nature Communications profile →
m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition

2017 430 citations Boxuan Zhao, Xiao Wang et al. profile →
N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis

2017 427 citations Raghu Ram Edupuganti, Simon Geiger et al. Nature Structural & Molecular Biology profile →
The m ⁶ A Reader ECT2 Controls Trichome Morphology by Affecting mRNA Stability in Arabidopsis

2018 292 citations Lian-Huan Wei, Peizhe Song et al. The Plant Cell profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Zhike Lu	22.6k	9.9k	3.6k	1.7k	765	54	23.7k
Dali Han	13.2k 0.6×	5.8k 0.6×	1.7k 0.5×	973 0.6×	229 0.3×	45	13.8k
Jianjun Chen	10.5k 0.5×	5.4k 0.5×	602 0.2×	1.4k 0.8×	498 0.7×	270	13.5k
Yang Wang	8.1k 0.4×	3.8k 0.4×	369 0.1×	793 0.5×	524 0.7×	225	9.5k
Shu‐Bing Qian	7.2k 0.3×	2.3k 0.2×	574 0.2×	618 0.4×	866 1.1×	68	9.0k
Stephen C. West	23.3k 1.0×	3.5k 0.4×	182 0.1×	4.6k 2.6×	482 0.6×	241	25.4k
Maria Jasin	24.8k 1.1×	4.1k 0.4×	136 0.0×	6.7k 3.9×	658 0.9×	206	27.4k
Ryan A. Flynn	12.9k 0.6×	5.0k 0.5×	207 0.1×	618 0.4×	415 0.5×	69	14.3k
Schraga Schwartz	12.2k 0.5×	5.0k 0.5×	1.1k 0.3×	591 0.3×	227 0.3×	65	12.7k
Anthony K. L. Leung	5.6k 0.2×	1.4k 0.1×	230 0.1×	1.5k 0.9×	305 0.4×	81	7.3k
Gregory J. Goodall	13.3k 0.6×	9.5k 1.0×	64 0.0×	2.8k 1.6×	357 0.5×	149	17.2k

Countries citing papers authored by Zhike Lu

Since Specialization

Citations

This map shows the geographic impact of Zhike Lu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Zhike Lu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Zhike Lu more than expected).

Fields of papers citing papers by Zhike Lu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Zhike Lu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Zhike Lu. The network helps show where Zhike Lu may publish in the future.

Co-authorship network of co-authors of Zhike Lu

This figure shows the co-authorship network connecting the top 25 collaborators of Zhike Lu. A scholar is included among the top collaborators of Zhike Lu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Zhike Lu. Zhike Lu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Wei, Rong, Lihong Ding, Zhike Lu, et al.. (2024). Improved split prime editors enable efficient in vivo genome editing. Cell Reports. 44(1). 115144–115144. 4 indexed citations

Liu, Yingzheng, et al.. (2024). The Transpeptidase Sortase A Binds Nucleic Acids and Mediates Mammalian Cell Labeling. Advanced Science. 11(21). e2305605–e2305605. 2 indexed citations

Liu, Yang, Renjie Song, Zhike Lu, et al.. (2023). The RNA m6A demethylase ALKBH5 drives emergency granulopoiesis and neutrophil mobilization by upregulating G-CSFR expression. Cellular and Molecular Immunology. 21(1). 6–18. 26 indexed citations

Yan, Jianfeng, Zhike Lu, Yangfan Zhou, et al.. (2023). Deep sampling of gRNA in the human genome and deep-learning-informed prediction of gRNA activities. Cell Discovery. 9(1). 48–48. 16 indexed citations

Gao, Minsong, Yini Li, Xiao Ou Shu, et al.. (2022). New Chromatin Run-On Reaction Enables Global Mapping of Active RNA Polymerase Locations in an Enrichment-free Manner. ACS Chemical Biology. 17(4). 768–775. 2 indexed citations

Liu, Yang, Renjie Song, Lu Zhao, et al.. (2022). m6A demethylase ALKBH5 is required for antibacterial innate defense by intrinsic motivation of neutrophil migration. Signal Transduction and Targeted Therapy. 7(1). 194–194. 58 indexed citations

Xue, Miaoge, Boxuan Zhao, Zijie Zhang, et al.. (2019). Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus. Nature Communications. 10(1). 4595–4595. 77 indexed citations

Liu, Yang, Zhike Lu, Yang Jiang, et al.. (2019). N ⁶ -methyladenosine RNA modification–mediated cellular metabolism rewiring inhibits viral replication. Science. 365(6458). 1171–1176. 171 indexed citations

Hou, Jiajie, He Zhang, Jun Liu, et al.. (2019). YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma. Molecular Cancer. 18(1). 268 indexed citations

10.

Hsu, Phillip J., Hailing Shi, Allen Zhu, et al.. (2019). The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine–containing mRNAs. Journal of Biological Chemistry. 294(52). 19889–19895. 93 indexed citations

11.

Wei, Lian-Huan, Peizhe Song, Ye Wang, et al.. (2018). The m ⁶ A Reader ECT2 Controls Trichome Morphology by Affecting mRNA Stability in Arabidopsis. The Plant Cell. 30(5). 968–985. 292 indexed citations breakdown →

12.

Liu, Jun, Mark A. Eckert, Bryan T. Harada, et al.. (2018). m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nature Cell Biology. 20(9). 1074–1083. 603 indexed citations breakdown →

13.

Li, Miaomiao, Xu Zhao, Wei Wang, et al.. (2018). Ythdf2-mediated m6A mRNA clearance modulates neural development in mice. Genome biology. 19(1). 69–69. 257 indexed citations

14.

Koranda, Jessica L., Hailing Shi, Meera Patel, et al.. (2018). Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning. Neuron. 99(2). 283–292.e5. 109 indexed citations

15.

Duan, Hong‐Chao, Lian-Huan Wei, Chi Zhang, et al.. (2017). ALKBH10B Is an RNA N ⁶ -Methyladenosine Demethylase Affecting Arabidopsis Floral Transition. The Plant Cell. 29(12). 2995–3011. 307 indexed citations

16.

Edupuganti, Raghu Ram, Simon Geiger, Rik G.H. Lindeboom, et al.. (2017). N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis. Nature Structural & Molecular Biology. 24(10). 870–878. 427 indexed citations breakdown →

17.

Shi, Hailing, Xiao Wang, Zhike Lu, et al.. (2017). YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA. Cell Research. 27(3). 315–328. 1392 indexed citations breakdown →

18.

Lichinchi, Gianluigi, Boxuan Zhao, Yinga Wu, et al.. (2016). Dynamics of Human and Viral RNA Methylation during Zika Virus Infection. Cell Host & Microbe. 20(5). 666–673. 306 indexed citations

19.

Liu, Jianzhao, Yanan Yue, Dali Han, et al.. (2013). A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation. Nature Chemical Biology. 10(2). 93–95. 2501 indexed citations breakdown →

20.

Tan, Minjia, Hao Luo, Sangkyu Lee, et al.. (2011). Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification. Cell. 146(6). 1016–1028. 1385 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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