Xin Chen

12.6k citations

244 papers · 9.6k indexed · 3 hit papers · h-index 49

Impact in

Immunology top 0.5%
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Immune Response and Inflammation
Toxicology top 0.2%
- Bioactive Compounds and Antitumor Agents

Papers in

Immunology 114
- Immune Cell Function and Interaction 54
- Immunotherapy and Immune Responses 44
- T-cell and B-cell Immunology 39
- Immune Response and Inflammation 25
- Psoriasis: Treatment and Pathogenesis 13
- Immune cells in cancer 13
Toxicology 7

Co-authors: Joost J. Oppenheim O. M. Zack Howard Malcolm Whitman Mengmeng Jiang Lu Yang Luis J. Montaner Daniela N. Männel Jin Wang
Journals: The Journal of Immunology (12 papers)Scientific Reports (7 papers)Frontiers in Immunology (7 papers)International Immunopharmacology (6 papers)Blood (5 papers)
Partner nations: China United States Macao

In The Last Decade

Xin Chen

224 papers receiving 9.4k citations

Hit Papers

align trajectories log scale

Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and therapy concepts 2020 · 517 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2020 Journal of Leukocyte Biology
2002 Nature Biotechnology
1996 Nature

Peers

Countries citing papers authored by Xin Chen

Since Specialization

Citations

This map shows the geographic impact of Xin Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xin Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xin Chen more than expected).

Fields of papers citing papers by Xin Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xin Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xin Chen. The network helps show where Xin Chen may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Xin Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Xin Chen Line = papers co-authored together Xin Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Interaction of major tea polyphenols with bovine milk proteins and its effect on in vitro bioaccessibility of tea polyphenols Food Chemistry ·Zhou Fei, AliA El-Sherbeni, Xin Chen, Zhenbao Jia, Fei Tao, Jiyu Peng	2025	9
2	P0848 Engineering and Development of a Novel Bispecific Antibody Targeting both TL1A and α4β7 for the Treatment of IBD Journal of Crohn s and Colitis ·Hao Ran, Jianmin Huang, Xintong Zhang, Sheng Li, Chuan Su, Chun Chen, Liu D, Ximing Xu, Xin Chen, Charles C. Lanfear, Lü Tian, Jianjun Peng, Zhenping Zhu	2025	1
3	Bispecific Antibody Targeting Both IL33 and TSLP for Asthma and COPD American Journal of Respiratory and Critical Care Medicine ·Haitao Ran, Jianmin Huang, Dolly Delagado, Dong Lin, David Liu, Ying Zhou, Chuan Su, Chao Chen, Ximing Xu, Xin Chen, Lü Tian, Jianjun Peng, Zhe Zhu	2025	2
4	AI-guided Engineering and Generation of Bispecific Antibodies Targeting Both IL13 and TSLP for Chronic Respiratory Diseases American Journal of Respiratory and Critical Care Medicine ·Rebekah Trask, Jianyong Huang, Dolly Delagado, Dong Lin, Di Liu, Chuan Su, Chao Chen, Ximing Xu, Xin Chen, Lü Tian, Jian Peng, Zhe Zhu	2025	1
5	Single-cell RNA sequencing identifies the prolactin receptor as a therapeutic target in adenomyosis Signal Transduction and Targeted Therapy ·KAREL THEIN, Shuai Xu, Qionghua Cui, Xin Chen, Xuelian Wang, Jinghao Liu, Jie Liu, Yuxuan Xin, Hao Shen, Fengxiang Lv, Lan Zhu, Xinli Hu, Rui‐Ping Xiao	2025	1
6	Collaborative augmented reconstruction of 3D neuron morphology in mouse and human brains Nature Methods ·Rita Morena Covizzi, Lei Huang, 金正祺, ناصر محب علیپور, 武建玲, Kaixiang Li, Lijun Wang, 暁冬顧, Xin Chen, S. Rama Mohan, Hiroomi Onda, Massimo Cavallo, Awani Bhushan, 直子仁杉, Jie Chen, J Zelcer, Lijuan Liu, Yimin Wang, (unknown)	2024	1
7	Microbiological and clinical effects of probiotic-related Zeger therapy on gingival health: a randomized controlled clinical trial BMC Oral Health ·Xin Chen, Yi Zhao, Kun Xue, Kaizad P. Sunavala, T.E. Konctantinova	2024	1
8	Ectoine Enhances Mucin Production Via Restoring IL-13/IFN-γ Balance in a Murine Dry Eye Model Investigative Ophthalmology & Visual Science ·Na Lin, Xin Chen, Haixia Liu, Ning Gao, Zhao Liu, Jin Li, Stephen C. Pflugfelder, De‐Quan Li	2024	1
9	Tissue injury and leukocyte changes in post-acute sequelae of SARS-CoV-2: review of 2833 post-acute patient outcomes per immune dysregulation and microbial translocation in long COVID Journal of Leukocyte Biology ·Md Sahidul Islam, Laurids Bruun, Mohamed Abdel‐Mohsen, Xin Chen, Luis J. Montaner	2023	15
10	The effects of unsaturated fatty acids on psoriasis: A two‐sample Mendelian randomization study Food Science & Nutrition ·Kai Li, Xin Chen, 강병렬, 直亮板橋, Adriana Arit, 十念中村, W Docters Van Leeuwex, Qian Wang, Yan Zheng	2023	3
11	Exosome-Modified Liposomes Targeted Delivery of Thalidomide to Regulate Treg Cells for Antitumor Immunotherapy Pharmaceutics ·Чакова Катерина Ігорівна, Qingfu Wang, Huimin Zou, Chon‐Kit Chou, Xin Chen	2023	8
12	Genetically predicted triglycerides mediate the relationship between type 2 diabetes Mellitus and intervertebral disc degeneration Lipids in Health and Disease ·Dingqiang Chen, Wenbin Xu, Xin Chen, 吴莘馨 Wu Xinxin, Zhiqiang Que, Naikun Sun, Rodrigo de Oliveira Grando, Gang Rui	2023	7
13	A deubiquitination module essential for T _reg fitness in the tumor microenvironment Science Advances ·Elena Montauti, Samuel E. Weinberg, Peng Chu, Shuvam Chaudhuri, Nikita Mani, Radhika Iyer, Yuanzhang Zhou, Yusi Zhang, よしえ若槻, Xin Chen, L. A. LAZUKINA, Juncheng Wei, Yana Zhang, Wantao Chen, Zhaolin Sun, Ming Yan, Deyu Fang	2022	35
14	Drug-guided screening for pancreatic lipase inhibitors in functional foods Food & Function ·Lujia Zhang, Jinkai Zheng, Mingzhe Ma, Yue Zhao, Jia Song, Xin Chen, Jeffrey Kuan, Xiao He, Changhu Xue, Qingjuan Tang	2021	15
15	Inhibition of two-pore channels in antigen-presenting cells promotes the expansion of TNFR2-expressing CD4 ⁺ Foxp3 ⁺ regulatory T cells Science Advances ·Danielli Guimaraes Costa, De Yang, Xiaoqing Li, Mengmeng Jiang, Md Sahidul Islam, Shaokui Chen, Yibo Chen, Yang Yang, Chon‐Kit Chou, Anna Trivett, Joost J. Oppenheim, Xin Chen	2020	17
16	Low expression of ZMYND8 correlates with aggressive features and poor prognosis in nasopharyngeal carcinoma SHILAP Revista de lepidopterología ·Jun Chen, Jia Liu, Xin Chen, Yuping Li, Li Z, Changbing Shen, Tian You, X. Zhang	2019	1
17	Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer Science Signaling ·Yingjie Nie, Jae-hyang Jeong, Hidekazu Shirota, Anna Trivett, De Yang, Dennis M. Klinman, Joost J. Oppenheim, Xin Chen	2018	58
18	The Alarmin HMGN1 Contributes to Antitumor Immunity and Is a Potent Immunoadjuvant Cancer Research ·Feng Wei, De Yang, Poonam Tewary, Yana Li, Sandra Li, Xin Chen, O. M. Zack Howard, Michael Bustin, Joost J. Oppenheim	2014	49
19	Development of regulatory T cells requires IL-7Rα stimulation by IL-7 or TSLP Blood ·Renata Mazzucchelli, Julie A. Hixon, Rosanne Spolski, Xin Chen, Wenqing Li, Veronica L. Hall, Jami Willette‐Brown, Arthur A. Hurwitz, Warren J. Leonard, Scott K. Durum	2008	102
20	Yin Zi Huang , an Injectable Multicomponent Chinese Herbal Medicine, Is a Potent Inhibitor of T-Cell Activation The Journal of Alternative and Complementary Medicine ·Xin Chen, Teresa Krakauer, Joost J. Oppenheim, O. M. Zack Howard	2004	21

About Xin Chen

Xin Chen is a scholar working on Immunology, Toxicology, Oncology, Cancer Research and Pharmacology, having authored 244 papers that have together received 9.6k indexed citations. Recurring topics across this work include Immune Cell Function and Interaction (54 papers), Immunotherapy and Immune Responses (44 papers), T-cell and B-cell Immunology (39 papers), Immune Response and Inflammation (25 papers), Psoriasis: Treatment and Pathogenesis (13 papers), Immune cells in cancer (13 papers), Cancer Immunotherapy and Biomarkers (10 papers) and Cytokine Signaling Pathways and Interactions (9 papers). The work is most often cited by research in Immunology (3.9k citations), Toxicology (487 citations), Oncology (1.4k citations), Molecular Biology (3.4k citations) and Complementary and alternative medicine (371 citations). Xin Chen has collaborated with scholars based in China, United States and Macao. Frequent co-authors include Joost J. Oppenheim, O. M. Zack Howard, Malcolm Whitman, Mengmeng Jiang, Lu Yang, Luis J. Montaner, Daniela N. Männel, Jin Wang, Ying Zheng and Ren‐He Xu. Their work appears in journals such as The Journal of Immunology, Scientific Reports, Frontiers in Immunology, International Immunopharmacology and Blood.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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