Xavier Morelli

2.8k citations

66 papers · 2.0k indexed · h-index 28

Computational Theory and Mathematics top 1%
- Computational Drug Discovery Methods 15
Virology top 5%
Molecular Biology top 10%
- Protein Structure and Dynamics 11
- Chemical Synthesis and Analysis 9
- Photosynthetic Processes and Mechanisms 6
Infectious Diseases top 5%
Hematology top 10%
Organic Chemistry
- Click Chemistry and Applications 9
Pharmacology
- Microbial Natural Products and Biosynthesis 6
Materials Chemistry
- Enzyme Structure and Function 6
Cell Biology
- Hippo pathway signaling and YAP/TAZ 6

Co-authors: Philippe Roche S. Betzi Raphaël Bourgeas Françoise Guerlesquin Alan C. Rigby Marianne A. Grant Yves Collette Laurent Hoffer
Cited by: Computational Theory and Mathematics Virology Molecular Biology
Journals: Journal of Biological Chemistry (6 papers)Journal of Medicinal Chemistry (6 papers)FEBS Letters (5 papers)
Partner nations: France China United States

In The Last Decade

Xavier Morelli

64 papers receiving 2.0k citations

Peers

Countries citing papers authored by Xavier Morelli

Since Specialization

Citations

This map shows the geographic impact of Xavier Morelli's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xavier Morelli with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xavier Morelli more than expected).

Fields of papers citing papers by Xavier Morelli

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xavier Morelli. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xavier Morelli. The network helps show where Xavier Morelli may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Xavier Morelli, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Xavier Morelli Line = papers co-authored together Xavier Morelli links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	NanoDSF Screening for Anti-tubulin Agents Uncovers New Structure–Activity Insights Journal of Medicinal Chemistry ·Viktoriia E. Baksheeva,M. Galeazzi,Diane Allegro,Carine Derviaux,Eddy Pasquier,Philippe Roche,Xavier Morelli,François Devred,Andrey V. Golovin,Philipp O. Tsvetkov	2025	0
2	PDZome-wide and structural characterization of the PDZ-binding motif of VANGL2 Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics ·Melody Lee,Gergő Gógl,Gustavo Labarca Garat,S. Betzi,E. Dluzewskka,A. Cousido-Siah,Hyo-Won Song,Rickard Göransson,Kristian Strømgaard,Søren Østergaard,Xavier Morelli,Gilles Travé,Renaud Vincentelli,Éric Bailly,Jean‐Paul Borg	2023	1
3	Fragment-based drug design targeting syntenin PDZ2 domain involved in exosomal release and tumour spread European Journal of Medicinal Chemistry ·Erik Höchel,Laurent Hoffer,Raphaël Leblanc,Tey Tsun Hang,Mikaël Feracci,Carine Derviaux,Antonio Luis Egea-Jiménez,Philippe Roche,Pascale Zimmermann,Xavier Morelli,Karine Barral	2021	9
4	Rational Design of PDZ Domain Inhibitors: Discovery of Small Organic Compounds Targeting PDZ Domains Methods in molecular biology ·Laurent Hoffer,Philippe Roche,Xavier Morelli	2021	4
5	In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor Molecular Oncology ·Bernhard U. Koelle,Gustavo Labarca Garat,Marion Le Grand,Laurent Hoffer,S. Betzi,Mikaël Feracci,Philipp O. Tsvetkov,François Devred,Yves Collette,Xavier Morelli,Pedro J. Ballester,Eddy Pasquier	2020	22
6	CovaDOTS: In Silico Chemistry-Driven Tool to Design Covalent Inhibitors Using a Linking Strategy Journal of Chemical Information and Modeling ·Laurent Hoffer,Magalí Sáez‐Ayala,Dragos Horvath,Alexandre Varnek,Xavier Morelli,Philippe Roche	2019	11
7	Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach Journal of Medicinal Chemistry ·Laurent Hoffer,L.M. Kokolova,李娅娟,Gustavo Labarca Garat,Christophe Müller,Alexey Yu. Fedorov,Carine Derviaux,Agnès Amouric,S. Betzi,Dragos Horvath,Alexandre Varnek,Yves Collette,Sébastien Combes,Philippe Roche,Xavier Morelli	2018	51
8	Optimization of a fragment linking hit toward Dengue and Zika virus NS5 methyltransferases inhibitors European Journal of Medicinal Chemistry ·Jessica Hernández-Rodríguez,Laurent Hoffer,Bruno Coutard,Gilles Quérat,Philippe Roche,Xavier Morelli,Étienne Decroly,Karine Barral	2018	20
9	2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein–protein interactions Database ·肖炜静,S. Betzi,Xavier Morelli,Philippe Roche	2016	56
10	Coronavirus Nsp10, a Critical Co-factor for Activation of Multiple Replicative Enzymes Journal of Biological Chemistry ·Mickaël Bouvet,Adrien Lugari,Clara C. Posthuma,典彦近藤,Stéphanie Bernard,S. Betzi,Isabelle Imbert,Bruno Canard,Jean‐Claude Guillemot,Patrick Lécine,Susanne Pfefferle,Christian Drosten,Eric J. Snijder,Étienne Decroly,Xavier Morelli	2014	155
11	Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG‐2‐interacting protein X (Alix) FEBS Letters ·Xiaoli Shi,S. Betzi,Adrien Lugari,Sandrine Opi,Audrey Restouin,Isabelle Parrot,Jean Martínez,Pascale Zimmermann,Patrick Lécine,Mingdong Huang,Stefan T. Arold,Yves Collette,Xavier Morelli	2012	6
12	Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides Biochimie ·Pierre Stocker,Jean Michel Brunel,Elizabeth F. Kingston,Antônia Tavares do Amaral,Xavier Morelli,Abd. Azis,Nicolas Vidal,Thierry Giardina,Josette Perrier	2012	6
13	Chemical and structural lessons from recent successes in protein–protein interaction inhibition (2P2I) Current Opinion in Chemical Biology ·Xavier Morelli,Raphaël Bourgeas,Philippe Roche	2011	164
14	Molecular Mapping of the RNA Cap 2′-O-Methyltransferase Activation Interface between Severe Acute Respiratory Syndrome Coronavirus nsp10 and nsp16* Journal of Biological Chemistry ·Adrien Lugari,S. Betzi,Étienne Decroly,Ku-Soo Guen,Aurélie Hermant,Jean-Claude Guillemot,Claire Debarnot,Jean‐Paul Borg,Mickaël Bouvet,Bruno Canard,Xavier Morelli,Patrick Lécine	2010	53
15	Protein-Protein Interaction Inhibition (2P2I): Fewer and Fewer Undruggable Targets Combinatorial Chemistry & High Throughput Screening ·S. Betzi,Françoise Guerlesquin,Xavier Morelli	2009	11
16	The Type I / Type II Cytochrome c3 Complex: an Electron Transfer Link in the Hydrogen-Sulfate Reduction Pathway Journal of Molecular Biology ·Lætitia Pieulle,Xavier Morelli,Philippe Gallice,Élisabeth Lojou,Pascale Barbier,Nofri Affandi,Pierre Bianco,Françoise Guerlesquin,E. Claude Hatchikian	2005	32
17	The cytochrome c₃–[Fe]‐hydrogenase electron‐transfer complex: structural model by NMR restrained docking FEBS Letters ·Putri,Xavier Morelli,Olivier Bornet,Claude E. Hatchikian,Mirjam Czjzek,Alain Dolla,Françoise Guerlesquin	2003	32
18	Structural basis of membrane binding by Gla domains of vitamin K–dependent proteins Nature Structural & Molecular Biology ·Mingdong Huang,Alan C. Rigby,Xavier Morelli,Marianne A. Grant,Guiqing Huang,Bruce Furie,Barbara A. Seaton,Barbara C. Furie	2003	185
19	¹⁵N‐labelling and preliminary heteronuclear NMR study ofDesulfovibrio vulgaris Hildenborough cytochrome c₅₅₃ European Journal of Biochemistry ·Xavier Morelli,Alain Dolla,René Toci,Françoise Guerlesquin	1999	5
20	Mapping the cytochrome c₅₅₃ interacting site using ¹H and ¹⁵N NMR FEBS Letters ·Xavier Morelli,Françoise Guerlesquin	1999	8

About Xavier Morelli

Xavier Morelli is a scholar working on Virology, Computational Theory and Mathematics and Molecular Biology, having authored 66 papers that have together received 2.0k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (15 papers), Protein Structure and Dynamics (11 papers), Chemical Synthesis and Analysis (9 papers), Click Chemistry and Applications (9 papers), Microbial Natural Products and Biosynthesis (6 papers), Enzyme Structure and Function (6 papers), Photosynthetic Processes and Mechanisms (6 papers) and Hippo pathway signaling and YAP/TAZ (6 papers). The work is most often cited by research in Computational Theory and Mathematics (525 citations), Virology (95 citations) and Molecular Biology (1.3k citations). Xavier Morelli has collaborated with scholars based in France, China and United States. Frequent co-authors include Philippe Roche, S. Betzi, Raphaël Bourgeas, Françoise Guerlesquin, Alan C. Rigby, Marianne A. Grant, Yves Collette, Laurent Hoffer, Adrien Lugari and Mingdong Huang. Their work appears in journals such as Journal of Biological Chemistry, Journal of Medicinal Chemistry, FEBS Letters, Biochemical Journal and Biochemistry.

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