Clara C. Posthuma

4.5k total citations · 2 hit papers
34 papers, 3.2k citations indexed

About

Clara C. Posthuma is a scholar working on Animal Science and Zoology, Infectious Diseases and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, Clara C. Posthuma has authored 34 papers receiving a total of 3.2k indexed citations (citations by other indexed papers that have themselves been cited), including 21 papers in Animal Science and Zoology, 20 papers in Infectious Diseases and 14 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in Clara C. Posthuma's work include Animal Virus Infections Studies (21 papers), Viral gastroenteritis research and epidemiology (18 papers) and Viral Infections and Immunology Research (14 papers). Clara C. Posthuma is often cited by papers focused on Animal Virus Infections Studies (21 papers), Viral gastroenteritis research and epidemiology (18 papers) and Viral Infections and Immunology Research (14 papers). Clara C. Posthuma collaborates with scholars based in Netherlands, Russia and France. Clara C. Posthuma's co-authors include Eric J. Snijder, Jessika C. Zevenhoven-Dobbe, Adriaan H. de Wilde, Alexander E. Gorbalenya, Bernadette G. van den Hoogen, Theo M. Bestebroer, Stefan van Nieuwkoop, Bruno Canard, Étienne Decroly and Dirk Jochmans and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nucleic Acids Research and Journal of Biological Chemistry.

In The Last Decade

Clara C. Posthuma

34 papers receiving 3.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture

2014 531 citations Adriaan H. de Wilde, Dirk Jochmans et al. profile →
One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

2014 414 citations Clara C. Posthuma, Jessika C. Zevenhoven-Dobbe et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Clara C. Posthuma Netherlands	24	2.3k	954	712	433	429	34	3.2k
Isabelle Imbert France	19	2.1k 0.9×	687 0.7×	869 1.2×	404 0.9×	196 0.5×	32	3.0k
Xiaotao Lu United States	19	2.6k 1.1×	736 0.8×	608 0.9×	256 0.6×	236 0.6×	27	3.3k
Jessika C. Zevenhoven-Dobbe Netherlands	21	3.5k 1.5×	1.4k 1.5×	952 1.3×	612 1.4×	657 1.5×	29	4.6k
Hanspeter Stalder Switzerland	21	2.2k 0.9×	450 0.5×	742 1.0×	564 1.3×	175 0.4×	46	3.6k
Burtram C. Fielding South Africa	26	2.9k 1.2×	763 0.8×	922 1.3×	135 0.3×	198 0.5×	53	4.0k
Jean K. Millet United States	23	3.4k 1.5×	1.2k 1.3×	899 1.3×	130 0.3×	519 1.2×	40	4.3k
Fernando Almazán Spain	34	2.6k 1.1×	1.5k 1.6×	1.0k 1.4×	675 1.6×	511 1.2×	68	4.2k
Sjoerd H. E. van den Worm Netherlands	14	1.5k 0.7×	507 0.5×	570 0.8×	266 0.6×	125 0.3×	16	2.5k
Barbara Selisko France	31	1.7k 0.7×	284 0.3×	1.1k 1.5×	400 0.9×	333 0.8×	59	3.4k
Martijn J. van Hemert Netherlands	27	2.0k 0.8×	358 0.4×	1.4k 1.9×	322 0.7×	215 0.5×	68	4.0k

Countries citing papers authored by Clara C. Posthuma

Since Specialization

Citations

This map shows the geographic impact of Clara C. Posthuma's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Clara C. Posthuma with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Clara C. Posthuma more than expected).

Fields of papers citing papers by Clara C. Posthuma

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Clara C. Posthuma. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Clara C. Posthuma. The network helps show where Clara C. Posthuma may publish in the future.

Co-authorship network of co-authors of Clara C. Posthuma

This figure shows the co-authorship network connecting the top 25 collaborators of Clara C. Posthuma. A scholar is included among the top collaborators of Clara C. Posthuma based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Clara C. Posthuma. Clara C. Posthuma is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ogando, Natacha S., Jessika C. Zevenhoven-Dobbe, Clara C. Posthuma, et al.. (2021). Structure–function analysis of the nsp14 N7–guanine methyltransferase reveals an essential role in Betacoronavirus replication. Proceedings of the National Academy of Sciences. 118(49). 29 indexed citations

Ogando, Natacha S., Jessika C. Zevenhoven-Dobbe, Yvonne van der Meer, et al.. (2020). The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2. Journal of Virology. 94(23). 172 indexed citations

Kim, Gyudong, Dnyandev B. Jarhad, Hong‐Rae Kim, et al.. (2019). Design, Synthesis, and Anti-RNA Virus Activity of 6′-Fluorinated-Aristeromycin Analogues. Journal of Medicinal Chemistry. 62(13). 6346–6362. 41 indexed citations

Ogando, Natacha S., François Ferrón, Étienne Decroly, et al.. (2019). The Curious Case of the Nidovirus Exoribonuclease: Its Role in RNA Synthesis and Replication Fidelity. Frontiers in Microbiology. 10. 1813–1813. 108 indexed citations

Wilde, Adriaan H. de, et al.. (2018). Cyclophilins and cyclophilin inhibitors in nidovirus replication. Virology. 522. 46–55. 55 indexed citations

Tuijtel, Maarten W., Aat A. Mulder, Clara C. Posthuma, et al.. (2017). Inducing fluorescence of uranyl acetate as a dual-purpose contrast agent for correlative light-electron microscopy with nanometre precision. Scientific Reports. 7(1). 10442–10442. 10 indexed citations

Wilde, Adriaan H. de, Jessika C. Zevenhoven-Dobbe, Corrine Beugeling, et al.. (2017). Coronaviruses and arteriviruses display striking differences in their cyclophilin A-dependence during replication in cell culture. Virology. 517. 148–156. 18 indexed citations

Posthuma, Clara C., Aartjan J.W. te Velthuis, & Eric J. Snijder. (2017). Nidovirus RNA polymerases: Complex enzymes handling exceptional RNA genomes. Virus Research. 234. 58–73. 82 indexed citations

Wilde, Adriaan H. de, Darryl Falzarano, Jessika C. Zevenhoven-Dobbe, et al.. (2016). Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model. Virus Research. 228. 7–13. 61 indexed citations

10.

Lehmann, Kathleen, Alexander E. Gorbalenya, Eric J. Snijder, & Clara C. Posthuma. (2015). Arterivirus RNA-dependent RNA polymerase: Vital enzymatic activity remains elusive. Virology. 487. 68–74. 10 indexed citations

11.

Lehmann, Kathleen, Anastasia Gulyaeva, Dmitry V. Samborskiy, et al.. (2015). Arterivirus nsp12 versus the coronavirus nsp16 2′-O-methyltransferase: comparison of the C-terminal cleavage products of two nidovirus pp1ab polyproteins. Journal of General Virology. 96(9). 2643–2655. 16 indexed citations

12.

Jochmans, Dirk, Adriaan H. de Wilde, Clara C. Posthuma, et al.. (2015). Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity. Bioorganic & Medicinal Chemistry Letters. 25(15). 2923–2926. 66 indexed citations

13.

Gooskens, Jairo, Jessika C. Zevenhoven-Dobbe, Eric C. J. Claas, Aloys C.M. Kroes, & Clara C. Posthuma. (2014). Mass Spectrometry-Based Comparative Sequence Analysis for the Genetic Monitoring of Influenza A(H1N1)pdm09 Virus. PLoS ONE. 9(4). e92970–e92970. 2 indexed citations

14.

Bouvet, Mickaël, Adrien Lugari, Clara C. Posthuma, et al.. (2014). Coronavirus Nsp10, a Critical Co-factor for Activation of Multiple Replicative Enzymes. Journal of Biological Chemistry. 289(37). 25783–25796. 155 indexed citations

15.

Lehmann, Kathleen, Eric J. Snijder, Clara C. Posthuma, & Alexander E. Gorbalenya. (2014). What we know but do not understand about nidovirus helicases. Virus Research. 202. 12–32. 49 indexed citations

16.

Deng, Zengqin, Kathleen Lehmann, Xiaorong Li, et al.. (2013). Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase. Nucleic Acids Research. 42(5). 3464–3477. 46 indexed citations

17.

Posthuma, Clara C., Martha T. van der Beek, Caroline S. de Brouwer, et al.. (2011). Mass spectrometry-based comparative sequencing to detect ganciclovir resistance in the UL97 gene of human cytomegalovirus. Journal of Clinical Virology. 51(1). 25–30. 7 indexed citations

18.

Raaben, Matthijs, Clara C. Posthuma, Monique H. Verheije, et al.. (2010). The Ubiquitin-Proteasome System Plays an Important Role during Various Stages of the Coronavirus Infection Cycle. Journal of Virology. 84(15). 7869–7879. 95 indexed citations

19.

Seybert, Anja, Clara C. Posthuma, Leonie C. van Dinten, et al.. (2004). A Complex Zinc Finger Controls the Enzymatic Activities of Nidovirus Helicases. Journal of Virology. 79(2). 696–704. 96 indexed citations

20.

Chaillou, Stéphane, B. Christien Lokman, Rob J. Leer, et al.. (1998). Cloning, Sequence Analysis, and Characterization of the Genes Involved in Isoprimeverose Metabolism inLactobacillus pentosus. Journal of Bacteriology. 180(9). 2312–2320. 45 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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