W.S. Fred Wong

8.3k citations

160 papers · 6.6k indexed · 1 hit paper · h-index 43

Impact in

Complementary and alternative medicine top 0.2%
- Andrographolide Research and Applications
Immunology top 1%
- Mast cells and histamine
- IL-33, ST2, and ILC Pathways

Papers in

Complementary and alternative medicine 23
- Andrographolide Research and Applications 22
Immunology 53
- Mast cells and histamine 17
- Inflammation biomarkers and pathways 10

Co-authors: Hong Yong Peh W.S. Daniel Tan Wupeng Liao Tze Khee Chan Jasmine H.P. Chan Bernard P. Leung Wanxing Eugene Ho Wei Duan
Journals: The Journal of Immunology (10 papers)Pharmacological Research (8 papers)British Journal of Pharmacology (7 papers)American Journal of Respiratory and Critical Care Medicine (5 papers)Biochemical Pharmacology (5 papers)
Partner nations: Singapore United States United Kingdom

In The Last Decade

W.S. Fred Wong

155 papers receiving 6.4k citations

Hit Papers

align trajectories log scale

Artemisinins: Pharmacological actions beyond anti-malarial 2013 · 385 citations

Peers

Countries citing papers authored by W.S. Fred Wong

Since Specialization

Citations

This map shows the geographic impact of W.S. Fred Wong's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by W.S. Fred Wong with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites W.S. Fred Wong more than expected).

Fields of papers citing papers by W.S. Fred Wong

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by W.S. Fred Wong. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by W.S. Fred Wong. The network helps show where W.S. Fred Wong may publish in the future.

Co-authors

The 25 scholars most cited alongside W.S. Fred Wong, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with W.S. Fred Wong Line = papers co-authored together W.S. Fred Wong links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Discovery of an NF-κB1 p105 Degrader for Anti-Inflammatory Therapy via Structural Optimization of the Coumarin Natural Product Minutuminolate Journal of Medicinal Chemistry ·Malcolm Z. Y. Choo, E. Lim, W.S. Fred Wong, Christina L. L. Chai	2025	0
2	Formoterol, the Most Effective Bronchodilator, Has No Anti-Inflammatory nor Metabolic Modulatory Effects in Severe Asthma Induced by Aspergillus fumigatus ACS Pharmacology & Translational Science ·Phyllis X.L. Gan, Kira M. Linke, Wupeng Liao, W.S. Fred Wong	2025	0
3	Calcaratarin D, a labdane diterpenoid, attenuates bleomycin-induced pulmonary fibrosis by blocking Wnt/β-catenin signaling pathway Pharmacological Research ·Wupeng Liao, Yuet Ang, Adrian Kee, Valencia Lim, Albert Yick Hou Lim, Christina L. L. Chai, W.S. Fred Wong	2025	1
4	Privileged natural product compound classes for anti-inflammatory drug development Natural Product Reports ·Malcolm Z. Y. Choo, J. Chua, S. Lee, Yuet Ang, W.S. Fred Wong, Christina L. L. Chai	2025	3
5	Dexamethasone protects against Aspergillus fumigatus-induced severe asthma via modulating pulmonary immunometabolism Pharmacological Research ·Phyllis X.L. Gan, Wupeng Liao, Hui Fang Lim, W.S. Fred Wong	2023	10
6	Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function British Journal of Pharmacology ·Wupeng Liao, Hazel Yu Ci Foo, Quy T.N. Tran, Christina L. L. Chai, W.S. Fred Wong	2022	6
7	Active p38α causes macrovesicular fatty liver in mice Proceedings of the National Academy of Sciences ·Ilona Darlyuk‐Saadon, Chen Bai, Chew Kiat Matthew Heng, Nechama Gilad, Weiping Yu, Pei Yen Lim, Amaury Cazenave‐Gassiot, Yongliang Zhang, W.S. Fred Wong, David Engelberg	2021	17
8	Polypharmacology of andrographolide: beyond one molecule one target Natural Product Reports ·Quy T.N. Tran, W.S. Daniel Tan, W.S. Fred Wong, Christina L. L. Chai	2020	27
9	Activation of angiotensin II type-2 receptor protects against cigarette smoke-induced COPD Pharmacological Research ·Dan Mei, W.S. Daniel Tan, Wupeng Liao, Chew Kiat Matthew Heng, W.S. Fred Wong	2020	15
10	The identification of naturally occurring labdane diterpenoid calcaratarin D as a potential anti-inflammatory agent European Journal of Medicinal Chemistry ·Quy T.N. Tran, W.S. Fred Wong, Christina L. L. Chai	2019	19
11	Dysregulated autophagy in COPD: A pathogenic process to be deciphered Pharmacological Research ·W.S. Daniel Tan, Han‐Ming Shen, W.S. Fred Wong	2019	47
12	Is there a future for andrographolide to be an anti-inflammatory drug? Deciphering its major mechanisms of action Biochemical Pharmacology ·W.S. Daniel Tan, Wupeng Liao, Shuo Zhou, W.S. Fred Wong	2017	135
13	Blomia tropicalis–Specific TCR Transgenic Th2 Cells Induce Inducible BALT and Severe Asthma in Mice by an IL-4/IL-13–Dependent Mechanism The Journal of Immunology ·Yen Leong Chua, Ka Hang Liong, Chiung-Hui Huang, Hok Sum Wong, Qian Zhou, Say Siong Ler, Yafang Tang, Chin Pei Low, Hui Yu Koh, I-Chun Kuo, Yongliang Zhang, W.S. Fred Wong, Hong Yong Peh, Hwee Ying Lim, Moyar Q. Ge, Angela Haczku, Véronique Angeli, Paul A. MacAry, Kaw Yan Chua, David M. Kemeny	2016	10
14	SRS06, a New Semisynthetic Andrographolide Derivative with Improved Anticancer Potency and Selectivity, Inhibits Nuclear Factor-κB Nuclear Binding in the A549 Non-Small Cell Lung Cancer Cell Line Pharmacology ·Jonathan Chee Woei Lim, Ethel Jeyaseela Jeyaraj, Sreenivasa Rao Sagineedu, W.S. Fred Wong, Johnson Stanslas	2015	20
15	Anti-malarial drug artesunate restores metabolic changes in experimental allergic asthma DSpace@MIT (Massachusetts Institute of Technology) ·Yong‐Jiang Xu, Fengguo Xu, Cheng Chang, Shaomin Huang, Hong Yong Peh, Choon Nam Ong, W.S. Fred Wong, Wanxing Eugene Ho, Steven R. Tannenbaum	2014	1
16	Synergistic antileukemia effect of genistein and chemotherapy in mouse xenograft model and potential mechanism through MAPK signaling Experimental Hematology ·Jing Shen, Yan‐Chin Tai, Jianbiao Zhou, Ching-Ho Stephen Wong, Pek Tan S. Cheang, W.S. Fred Wong, Zhigang Xie, Matiullah Khan, Jin-Hua Han, Chien-Shing Chen	2006	31
17	Inhaled p38α Mitogen-activated Protein Kinase Antisense Oligonucleotide Attenuates Asthma in Mice American Journal of Respiratory and Critical Care Medicine ·Wei Duan, Jasmine H.P. Chan, Kelly McKay, Jeffrey R. Crosby, Hui Hwa Choo, Bernard P. Leung, James G. Karras, W.S. Fred Wong	2004	129
18	An anti-inflammatory role for a phosphoinositide 3-kinase inhibitor LY294002 in a mouse asthma model International Immunopharmacology ·Wei Duan, Ana M.K. Aguinaldo Datiles, Bernard P. Leung, Chris J. Vlahos, W.S. Fred Wong	2004	103
19	Inhibitors of Tyrosine Kinase Signaling Cascade Attenuated Antigen Challenge of Guinea-Pig Airways In Vitro American Journal of Respiratory and Critical Care Medicine ·Fai Tsang, W.S. Fred Wong	2000	23
20	Pharmacological and histological examinations of regional differences of guinea‐pig lung: a role of pleural surface smooth muscle in lung strip contraction British Journal of Pharmacology ·W.S. Fred Wong, Shari L. Bloomquist, Alison M. Bendele, Jerome H. Fleisch	1992	11

About W.S. Fred Wong

W.S. Fred Wong is a scholar working on Complementary and alternative medicine, Immunology, Microbiology, Immunology and Allergy and Physiology, having authored 160 papers that have together received 6.6k indexed citations. Recurring topics across this work include Asthma and respiratory diseases (51 papers), Andrographolide Research and Applications (22 papers), Mast cells and histamine (17 papers), Chronic Obstructive Pulmonary Disease (COPD) Research (13 papers), Antimicrobial Peptides and Activities (11 papers), Inflammation biomarkers and pathways (10 papers), Cytokine Signaling Pathways and Interactions (8 papers) and Allergic Rhinitis and Sensitization (8 papers). The work is most often cited by research in Complementary and alternative medicine (917 citations), Immunology (1.6k citations), Immunology and Allergy (361 citations), Physiology (1.3k citations) and Pharmacology (348 citations). W.S. Fred Wong has collaborated with scholars based in Singapore, United States and United Kingdom. Frequent co-authors include Hong Yong Peh, W.S. Daniel Tan, Wupeng Liao, Tze Khee Chan, Jasmine H.P. Chan, Bernard P. Leung, Wanxing Eugene Ho, Wei Duan, Cheng Chang and Han‐Ming Shen. Their work appears in journals such as The Journal of Immunology, Pharmacological Research, British Journal of Pharmacology, American Journal of Respiratory and Critical Care Medicine and Biochemical Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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