Wolfgang Löscher

44.8k total citations · 12 hit papers
606 papers, 34.1k citations indexed

About

Wolfgang Löscher is a scholar working on Cellular and Molecular Neuroscience, Psychiatry and Mental health and Pediatrics, Perinatology and Child Health. According to data from OpenAlex, Wolfgang Löscher has authored 606 papers receiving a total of 34.1k indexed citations (citations by other indexed papers that have themselves been cited), including 348 papers in Cellular and Molecular Neuroscience, 314 papers in Psychiatry and Mental health and 237 papers in Pediatrics, Perinatology and Child Health. Recurrent topics in Wolfgang Löscher's work include Neuroscience and Neuropharmacology Research (325 papers), Epilepsy research and treatment (309 papers) and Pharmacological Effects and Toxicity Studies (221 papers). Wolfgang Löscher is often cited by papers focused on Neuroscience and Neuropharmacology Research (325 papers), Epilepsy research and treatment (309 papers) and Pharmacological Effects and Toxicity Studies (221 papers). Wolfgang Löscher collaborates with scholars based in Germany, United States and Austria. Wolfgang Löscher's co-authors include Heidrun Potschka, Dieter Schmidt, Michael A. Rogawski, Claudia Brandt, Ulrich Ebert, Dagmar Hönack, Maren Fedrowitz, Chris Rundfeldt, Marion Bankstahl and John F. Deeken and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Lancet and Nature Medicine.

In The Last Decade

Wolfgang Löscher

597 papers receiving 33.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The neurobiology of antiepileptic drugs

2004 891 citations Wolfgang Löscher et al. profile →
Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations

1988 698 citations Wolfgang Löscher et al. profile →
Drug resistance in brain diseases and the role of drug efflux transporters

2005 681 citations Wolfgang Löscher, Heidrun Potschka profile →
Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs

2011 664 citations Wolfgang Löscher profile →
Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

2004 642 citations Wolfgang Löscher, Heidrun Potschka PubMed profile →
Drug Resistance in Epilepsy: Clinical Impact, Potential Mechanisms, and New Innovative Treatment Options

2020 535 citations Wolfgang Löscher, Heidrun Potschka et al. profile →
The Blood-Brain Barrier and Cancer: Transporters, Treatment, and Trojan Horses

2007 531 citations Wolfgang Löscher et al. profile →
New avenues for anti-epileptic drug discovery and development

2013 476 citations Wolfgang Löscher, Henrik Klitgaard et al. profile →
Modern antiepileptic drug development has failed to deliver: Ways out of the current dilemma

2011 414 citations Wolfgang Löscher et al. Epilepsia profile →
Infections, inflammation and epilepsy

2015 352 citations Annamaria Vezzani, H. Steve White et al. profile →
The Pharmacology and Clinical Efficacy of Antiseizure Medications: From Bromide Salts to Cenobamate and Beyond

2021 186 citations Wolfgang Löscher, Pavel Klein profile →
New epilepsy therapies in development

2024 51 citations Pavel Klein, Wolfgang Löscher et al. profile →

Peers

Countries citing papers authored by Wolfgang Löscher

Since Specialization

Citations

This map shows the geographic impact of Wolfgang Löscher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wolfgang Löscher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wolfgang Löscher more than expected).

Fields of papers citing papers by Wolfgang Löscher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wolfgang Löscher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wolfgang Löscher. The network helps show where Wolfgang Löscher may publish in the future.

Co-authorship network of co-authors of Wolfgang Löscher

This figure shows the co-authorship network connecting the top 25 collaborators of Wolfgang Löscher. A scholar is included among the top collaborators of Wolfgang Löscher based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Wolfgang Löscher. Wolfgang Löscher is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Temporal development of seizure threshold and spontaneous seizures after neonatal asphyxia and the effect of prophylactic treatment with midazolam in rats 2024 ·Experimental Neurology ·(unknown), (unknown), André Merten, (unknown), Wolfgang Löscher	1
2	A comparison of the antiepileptogenic efficacy of two rationally chosen multitargeted drug combinations in a rat model of posttraumatic epilepsy 2024 ·Experimental Neurology ·Mustafa Q. Hameed, Raimondo D’Ambrosio, (unknown), (unknown), Rui Lin, (unknown), (unknown), (unknown), Pavel Klein, Chris Rundfeldt, Wolfgang Löscher, Alexander Rotenberg	2
3	Epilepsy and epileptiform activity in late-onset Alzheimer disease: clinical and pathophysiological advances, gaps and conundrums 2024 ·Nature Reviews Neurology ·Anita Kamondi, Madeleine Grigg‐Damberger, Wolfgang Löscher, Heikki Tanila, András Horváth	32
4	The ups and downs of alkyl‐carbamates in epilepsy therapy: How does cenobamate differ? 2021 ·Epilepsia ·Wolfgang Löscher, Graeme J. Sills, H. Steve White	48
5	Phenobarbital and midazolam suppress neonatal seizures in a noninvasive rat model of birth asphyxia, whereas bumetanide is ineffective 2020 ·Epilepsia ·(unknown), Kerstin Römermann, (unknown), (unknown), Wiebke Theilmann, (unknown), Kai Kaila, Wolfgang Löscher	32
6	Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy? 2020 ·Epilepsia ·Pavel Klein, Alon Friedman, Mustafa Q. Hameed, Rafał M. Kamiński, Guy Bar‐Klein, Henrik Klitgaard, (unknown), Sergiusz Jóźwiak, David A. Prince, Alexander Rotenberg, Roy E. Twyman, Annamaria Vezzani, Michael Wong, Wolfgang Löscher	75
7	The search for brain-permeant NKCC1 inhibitors for the treatment of seizures: Pharmacokinetic-pharmacodynamic modelling of NKCC1 inhibition by azosemide, torasemide, and bumetanide in mouse brain 2020 ·Epilepsy & Behavior ·(unknown), Kerstin Römermann, (unknown), Wolfgang Löscher	24
8	Lack of antidepressant effects of burst-suppressing isoflurane anesthesia in adult male Wistar outbred rats subjected to chronic mild stress 2020 ·PLoS ONE ·Wiebke Theilmann, (unknown), (unknown), Wolfgang Löscher, Tomi Rantamäki	6
9	4-(Difluoromethyl)-5-(4-((3R,5S)-3,5-dimethylmorpholino)-6-((R)-3-methylmorpholino)-1,3,5-triazin-2-yl)pyridin-2-amine (PQR626), a Potent, Orally Available, and Brain-Penetrant mTOR Inhibitor for the Treatment of Neurological Disorders 2020 ·Journal of Medicinal Chemistry ·Chiara Borsari, Erhan Keleş, Denise Rageot, (unknown), Thomas Bohnacker, (unknown), (unknown), Anna Melone, Rohitha Sriramaratnam, Florent Beaufils, Matthias Hamburger, Paul Hebeisen, Wolfgang Löscher, Doriano Fabbro, Petra Hillmann, Matthias P. Wymann	18
10	The circadian dynamics of the hippocampal transcriptome and proteome is altered in experimental temporal lobe epilepsy 2020 ·Science Advances ·Konrad J. Dębski, Nicholas Ceglia, Antoine Ghestem, Anton Ivanov, Giulio Emilio Brancati, Sonja Bröer, Anna Bot, Johannes Alexander Müller, Susanne Schoch, Albert J. Becker, Wolfgang Löscher, Maxime Guye, (unknown), Katarzyna Łukasiuk, Pierre Baldi, Christophe Bernard	52
11	Blood–Brain Barrier Leakage during Early Epileptogenesis Is Associated with Rapid Remodeling of the Neurovascular Unit 2018 ·eNeuro ·Marion Bankstahl, (unknown), (unknown), (unknown), Pablo Bascuñana, Dominik Michalski, Frank M. Bengel, Wolfgang Löscher, Martin Meier, Jens P. Bankstahl, Wolfgang Härtig	46
12	Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B 2018 ·Scientific Reports ·(unknown), Kerstin Römermann, Nanna MacAulay, Wolfgang Löscher	34
13	P11 promoter methylation predicts the antidepressant effect of electroconvulsive therapy 2018 ·Translational Psychiatry ·Alexandra Neyazi, Wiebke Theilmann, Claudia Brandt, Tomi Rantamäki, Nobuaki Matsui, Mathias Rhein, Johannes Kornhuber, Malek Bajbouj, Wolfgang Sperling, Stefan Bleich, Helge Frieling, Wolfgang Löscher	31
14	Neuroinflammatory targets and treatments for epilepsy validated in experimental models 2017 ·Epilepsia ·Eleonora Aronica, Sebastian Bauer, Yuri Bozzi, Matteo Caleo, Raymond Dingledine, Jan A. Gorter, David C. Henshall, Daniela Kaufer, Sookyong Koh, Wolfgang Löscher, Jean‐Pierre Louboutin, Michele Mishto, Braxton A. Norwood, Eleonora Palma, Michael O. Poulter, Gaetano Terrone, Annamaria Vezzani, Rafał M. Kamiński	151
15	(R)-[11C]verapamil is selectively transported by murine and human P-glycoprotein at the blood–brain barrier, and not by MRP1 and BCRP 2013 ·Nuclear Medicine and Biology ·Kerstin Römermann, Thomas Wanek, Marion Bankstahl, Jens P. Bankstahl, Maren Fedrowitz, Markus Müller, Wolfgang Löscher, Claudia Kuntner, Oliver Langer	64
16	Animal models of seizures and epilepsy 2011 ·The biomedical & life sciences collection. ·Wolfgang Löscher	6
17	Histological Examination in a Blind-deafness Rat Mutant – A Rodent Model for Usher Syndrome Phenotype 1 2003 ·Investigative Ophthalmology & Visual Science ·S. Lindemann, Kenji Kamino, Dirk Wedekind, Hans J. Hedrich, R M Winter, Wolfgang Löscher, (unknown)	1
18	Magnetic field exposure increases cell proliferation but does not affect melatonin levels in the mammary gland of female Sprague Dawley rats. 2002 ·PubMed ·Maren Fedrowitz, Jürgen Westermann, Wolfgang Löscher	35
19	P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain 2001 ·Neuroreport ·Heidrun Potschka, Maren Fedrowitz, Wolfgang Löscher	172
20	Trans-2-en-valproic Acid Limits Action Potential Firing Frequency in Mouse Central Neurons in Cell Culture 1997 ·Journal of Pharmacology and Experimental Therapeutics ·Artur W. Wamil, Wolfgang Löscher, Michael J. McLean	5

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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