William G. Helferich

12.4k total citations · 2 hit papers
117 papers, 6.7k citations indexed

About

William G. Helferich is a scholar working on Pathology and Forensic Medicine, Genetics and Molecular Biology. According to data from OpenAlex, William G. Helferich has authored 117 papers receiving a total of 6.7k indexed citations (citations by other indexed papers that have themselves been cited), including 50 papers in Pathology and Forensic Medicine, 40 papers in Genetics and 30 papers in Molecular Biology. Recurrent topics in William G. Helferich's work include Phytoestrogen effects and research (49 papers), Estrogen and related hormone effects (28 papers) and Cancer Risks and Factors (16 papers). William G. Helferich is often cited by papers focused on Phytoestrogen effects and research (49 papers), Estrogen and related hormone effects (28 papers) and Cancer Risks and Factors (16 papers). William G. Helferich collaborates with scholars based in United States, China and France. William G. Helferich's co-authors include Daniel R. Doerge, Young H. Ju, Kimberly F. Allred, Ross Santell, Clinton D. Allred, Ching‐Yi Hsieh, Sandra Z. Haslam, John A. Katzenellenbogen, Benita S. Katzenellenbogen and Juan E. Andrade and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Angewandte Chemie International Edition and PLoS ONE.

In The Last Decade

William G. Helferich

115 papers receiving 6.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Investigating the optimal size of anticancer nanomedicine

2014 563 citations Xujuan Yang, James A. Hartman et al. Proceedings of the National Academy of Sciences profile →
Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo.

1998 501 citations Ross Santell, William G. Helferich et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
William G. Helferich United States	43	2.6k	2.1k	1.9k	1.1k	694	117	6.7k
Kenneth R. Reuhl United States	45	1.4k 0.5×	2.4k 1.1×	525 0.3×	681 0.6×	291 0.4×	141	7.6k
Kyung‐Chul Choi South Korea	48	659 0.3×	3.0k 1.4×	1.6k 0.8×	1.2k 1.1×	451 0.6×	271	8.4k
Sebastiano Andò Italy	63	672 0.3×	5.5k 2.6×	3.7k 1.9×	2.8k 2.4×	1.8k 2.5×	287	12.8k
Keiichiro Suzuki Japan	55	590 0.2×	5.0k 2.4×	830 0.4×	298 0.3×	453 0.7×	197	8.5k
Frank Arfuso Australia	56	775 0.3×	5.5k 2.6×	480 0.2×	1.8k 1.6×	535 0.8×	131	10.2k
Jacques Magdalou France	43	453 0.2×	3.0k 1.4×	458 0.2×	1.2k 1.0×	504 0.7×	259	7.5k
Imtiaz A. Siddiqui United States	50	1.3k 0.5×	2.6k 1.2×	298 0.2×	611 0.5×	249 0.4×	88	6.2k
Man‐Sau Wong Hong Kong	40	752 0.3×	3.1k 1.4×	547 0.3×	436 0.4×	362 0.5×	188	5.0k
Robert C. Tuckey Australia	52	4.3k 1.6×	1.4k 0.7×	1.7k 0.9×	581 0.5×	1.8k 2.6×	161	8.6k
Dieter Steinhilber Germany	49	573 0.2×	3.9k 1.8×	1.0k 0.5×	984 0.9×	357 0.5×	296	9.6k

Countries citing papers authored by William G. Helferich

Since Specialization

Citations

This map shows the geographic impact of William G. Helferich's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William G. Helferich with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William G. Helferich more than expected).

Fields of papers citing papers by William G. Helferich

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William G. Helferich. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William G. Helferich. The network helps show where William G. Helferich may publish in the future.

Co-authorship network of co-authors of William G. Helferich

This figure shows the co-authorship network connecting the top 25 collaborators of William G. Helferich. A scholar is included among the top collaborators of William G. Helferich based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William G. Helferich. William G. Helferich is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Zhang, Xiyuan, Katherine L. Cook, Anni Wärri, et al.. (2017). Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats. Clinical Cancer Research. 23(3). 814–824. 51 indexed citations

Gao, Liying, et al.. (2016). Equol inhibits growth, induces atresia, and inhibits steroidogenesis of mouse antral follicles in vitro. Toxicology and Applied Pharmacology. 295. 47–55. 13 indexed citations

Doerge, Daniel R., Kellie A. Woodling, Mona I. Churchwell, Stefanie C. Fleck, & William G. Helferich. (2016). Pharmacokinetics of isoflavones from soy infant formula in neonatal and adult rhesus monkeys. Food and Chemical Toxicology. 92. 165–176. 17 indexed citations

Khan, Shabana I., Ikhlas A. Khan, Zulfıqar Ali, et al.. (2015). The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro. Archives of Biochemistry and Biophysics. 591. 98–110. 60 indexed citations

Andruska, Neal, Xiaobin Zheng, Xujuan Yang, et al.. (2015). Estrogen receptor α inhibitor activates the unfolded protein response, blocks protein synthesis, and induces tumor regression. Proceedings of the National Academy of Sciences. 112(15). 4737–4742. 67 indexed citations

Yang, Xujuan, Aashvini Belosay, James A. Hartman, et al.. (2015). Dietary soy isoflavones increase metastasis to lungs in an experimental model of breast cancer with bone micro-tumors. Clinical & Experimental Metastasis. 32(4). 323–333. 38 indexed citations

Strakovsky, Rita S., Stéphane Lezmi, Jodi A. Flaws, et al.. (2013). Genistein Exposure During the Early Postnatal Period Favors the Development of Obesity in Female, But Not Male Rats. Toxicological Sciences. 138(1). 161–174. 35 indexed citations

Dávila, Juanmahel, Gail C. Ekman, Rachel N. Andrews, et al.. (2010). Acute and Chronic Effects of Oral Genistein Administration in Neonatal Mice1. Biology of Reproduction. 83(1). 114–121. 50 indexed citations

Wang, Victor, Helen J.K. Sable, Young H. Ju, et al.. (2008). Effects of chronic estradiol treatment on delayed spatial alternation and differential reinforcement of low rates of responding.. Behavioral Neuroscience. 122(4). 794–804. 35 indexed citations

10.

Helferich, William G., Juan E. Andrade, & Martin S. Hoagland. (2008). Phytoestrogens and breast cancer: a complex story. Inflammopharmacology. 16(5). 219–226. 117 indexed citations

11.

Ju, Young H., Daniel R. Doerge, & William G. Helferich. (2007). A dietary supplement for female sexual dysfunction, Avlimil, stimulates the growth of estrogen-dependent breast tumors (MCF-7) implanted in ovariectomized athymic nude mice. Food and Chemical Toxicology. 46(1). 310–320. 11 indexed citations

12.

Selvaraj, Vimal, Afia Naaz, Motoko Mukai, et al.. (2004). Estrogenicity of the Isoflavone Metabolite Equol on Reproductive and Non-Reproductive Organs in Mice1. Biology of Reproduction. 71(3). 966–972. 52 indexed citations

13.

Ju, Young H., et al.. (2004). β-Sitosterol, β-Sitosterol Glucoside, and a Mixture of β-Sitosterol and β-Sitosterol Glucoside Modulate the Growth of Estrogen-Responsive Breast Cancer Cells In Vitro and in Ovariectomized Athymic Mice. Journal of Nutrition. 134(5). 1145–1151. 149 indexed citations

14.

Denison, Michael S. & William G. Helferich. (1998). Toxicant-receptor interactions : modulation of signal transduction and gene expression. Taylor & Francis eBooks. 10 indexed citations

15.

Santell, Ross, et al.. (1998). The effect of genistein upon estrogen receptor negative human breast cancer cell growth in vitro and in vivo. The FASEB Journal. 12(5). 2 indexed citations

16.

Nair, Muraleedharan G., et al.. (1997). Effects of dihydrogenistein, a metabolite of genistein, on human breast cancer (MCF-7 and MDA-231) cells in vitro. The FASEB Journal. 11(3). 1 indexed citations

17.

Helferich, William G. & Michael S. Denison. (1991). Ultraviolet Photoproducts of Tryptophan Can Act as Dioxin Agonists. Molecular Pharmacology. 40(5). 674–678. 65 indexed citations

18.

Anderson, Peter T., et al.. (1990). Ractopamine Increases Total and Myofibrillar Protein Synthesis in Cultured Rat Myotubes. Journal of Nutrition. 120(12). 1677–1683. 31 indexed citations

19.

Helferich, William G. & D.C. Westhoff. (1980). All about yogurt. Prentice Hall eBooks. 1 indexed citations

20.

Mercer, H. Dwight, et al.. (1979). Use of the Double-Isotope Single-Injection Method for Estimating Renal Function in Normal Cross-Bred Swine. American Journal of Veterinary Research. 40(4). 567–570. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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