William E. O’Brien

7.4k total citations
114 papers, 4.5k citations indexed

About

William E. O’Brien is a scholar working on Molecular Biology, Clinical Biochemistry and Biochemistry. According to data from OpenAlex, William E. O’Brien has authored 114 papers receiving a total of 4.5k indexed citations (citations by other indexed papers that have themselves been cited), including 41 papers in Molecular Biology, 38 papers in Clinical Biochemistry and 28 papers in Biochemistry. Recurrent topics in William E. O’Brien's work include Metabolism and Genetic Disorders (38 papers), Amino Acid Enzymes and Metabolism (23 papers) and Biochemical and Molecular Research (15 papers). William E. O’Brien is often cited by papers focused on Metabolism and Genetic Disorders (38 papers), Amino Acid Enzymes and Metabolism (23 papers) and Biochemical and Molecular Research (15 papers). William E. O’Brien collaborates with scholars based in United States, Canada and Austria. William E. O’Brien's co-authors include Arthur L. Beaudet, Anthony R. Gregg, Sidney M. Morris, Tsung‐Sheng Su, Joseph H. Nadeau, Lars G. Ljungdahl, Fernando Scaglia, Lindsay C. Burrage, Annie E. Hill and Harland G. Wood and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

William E. O’Brien

113 papers receiving 4.4k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
William E. O’Brien United States 40 1.8k 1.0k 984 790 697 114 4.5k
Kirby D. Smith United States 39 4.6k 2.6× 879 0.8× 900 0.9× 1.5k 1.9× 465 0.7× 93 6.3k
Yin‐Hsiu Chien Taiwan 40 2.1k 1.2× 1.4k 1.4× 2.6k 2.6× 976 1.2× 301 0.4× 298 6.1k
W E O'Brien United States 27 1.3k 0.7× 558 0.5× 319 0.3× 675 0.9× 382 0.5× 66 2.6k
Marvin R. Natowicz United States 37 1.8k 1.0× 353 0.3× 1000 1.0× 1.1k 1.4× 123 0.2× 111 4.2k
Brian Lake United Kingdom 38 1.9k 1.1× 601 0.6× 1.8k 1.9× 278 0.4× 178 0.3× 140 4.4k
Gail E. Herman United States 33 3.2k 1.8× 287 0.3× 517 0.5× 2.6k 3.3× 221 0.3× 102 5.7k
João Ramalho‐Santos Portugal 46 3.9k 2.2× 372 0.4× 434 0.4× 1.0k 1.3× 146 0.2× 171 8.3k
Jean Michaud Canada 29 1.5k 0.8× 312 0.3× 348 0.4× 301 0.4× 121 0.2× 176 4.5k
Kari Majamaa Finland 41 4.3k 2.4× 2.0k 1.9× 615 0.6× 1.2k 1.5× 188 0.3× 187 6.7k
Jerome S. Handler United States 41 2.3k 1.3× 222 0.2× 584 0.6× 252 0.3× 400 0.6× 136 5.3k

Countries citing papers authored by William E. O’Brien

Since Specialization
Citations

This map shows the geographic impact of William E. O’Brien's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William E. O’Brien with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William E. O’Brien more than expected).

Fields of papers citing papers by William E. O’Brien

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William E. O’Brien. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William E. O’Brien. The network helps show where William E. O’Brien may publish in the future.

Co-authorship network of co-authors of William E. O’Brien

This figure shows the co-authorship network connecting the top 25 collaborators of William E. O’Brien. A scholar is included among the top collaborators of William E. O’Brien based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William E. O’Brien. William E. O’Brien is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
O’Brien, William E., et al.. (2012). Olympic Legacy: A Comparison of Barcelona 1992 and Athens 2004. Undergraduate Research Journal. 1(1). 19–27. 1 indexed citations
2.
Marini, Juan C., Brendan C. Lanpher, Fernando Scaglia, et al.. (2011). Phenylbutyrate improves nitrogen disposal via an alternative pathway without eliciting an increase in protein breakdown and catabolism in control and ornithine transcarbamylase–deficient patients. American Journal of Clinical Nutrition. 93(6). 1248–1254. 9 indexed citations
3.
Herbert, De’Broski R., Tatyana Orekov, Monica Ilies, et al.. (2010). Arginase I Suppresses IL-12/IL-23p40–Driven Intestinal Inflammation during Acute Schistosomiasis. The Journal of Immunology. 184(11). 6438–6446. 106 indexed citations
4.
Sun, Qin & William E. O’Brien. (2009). Diagnosis of Creatine Metabolism Disorders by Determining Creatine and Guanidinoacetate in Plasma and Urine. Methods in molecular biology. 603. 175–185. 5 indexed citations
5.
Shao, Haifeng, Lindsay C. Burrage, David S. Sinasac, et al.. (2008). Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis. Proceedings of the National Academy of Sciences. 105(50). 19910–19914. 198 indexed citations
6.
Meshaka, Walter E., et al.. (2005). The Geographically Contiguous and Expanding Coastal Range of the Northern Curlytail Lizard (Leiocephalus carinatus armouri) in Florida. Southeastern Naturalist. 4(3). 521–526. 7 indexed citations
7.
Misra, Vinod K., Eduard A. Struys, William E. O’Brien, et al.. (2005). Phenotypic heterogeneity in the presentation of d-2-hydroxyglutaric aciduria in monozygotic twins. Molecular Genetics and Metabolism. 86(1-2). 200–205. 13 indexed citations
8.
Enns, Gregory M., William E. O’Brien, Keiko Kobayashi, Haruhide Shinzawa, & Joan E. Pellegrino. (2005). Postpartum “Psychosis” in Mild Argininosuccinate Synthetase Deficiency. Obstetrics and Gynecology. 105(5). 1244–1246. 41 indexed citations
9.
Singer, Jonathan B., Annie E. Hill, Lindsay C. Burrage, et al.. (2004). Genetic Dissection of Complex Traits with Chromosome Substitution Strains of Mice. Science. 304(5669). 445–448. 260 indexed citations
10.
Scaglia, Fernando, Nicola Brunetti‐Pierri, Soledad Kleppe, et al.. (2004). Clinical Consequences of Urea Cycle Enzyme Deficiencies and Potential Links to Arginine and Nitric Oxide Metabolism. Journal of Nutrition. 134(10). 2775S–2782S. 69 indexed citations
11.
Scaglia, Fernando, Susan Carter, William E. O’Brien, & Brendan Lee. (2004). Effect of alternative pathway therapy on branched chain amino acid metabolism in urea cycle disorder patients. Molecular Genetics and Metabolism. 81. 79–85. 79 indexed citations
12.
Tempfer, Cle mens, et al.. (2000). Genetic contributions of the endothelial nitric oxide synthase gene to ovulation and menopause in a mouse model. Fertility and Sterility. 73(5). 1025–1031. 22 indexed citations
13.
Patejunas, Gerald, et al.. (1995). Exploring the role of histidines in the catalytic activity of duck δ-Crystallins using site-directed mutagenesis. Experimental Eye Research. 61(2). 151–154. 14 indexed citations
14.
Wong, Lee‐Jun C. & William E. O’Brien. (1995). Characterization of the cDNA and the Gene Encoding Murine Adenylosuccinate Lyase. Genomics. 28(2). 341–343. 11 indexed citations
15.
Jackson, Marian J., Linda Surh, William E. O’Brien, & Arthur L. Beaudet. (1990). Assignment of the structural gene for argininosuccinate synthetase to proximal mouse chromosome 2. Genomics. 6(3). 545–547. 10 indexed citations
16.
Northrup, Hope, Arthur L. Beaudet, & William E. O’Brien. (1990). Prenatal diagnosis of citrullinaemia: Review of a 10‐year experience including recent use of DNA analysis. Prenatal Diagnosis. 10(12). 771–779. 15 indexed citations
17.
Spence, J. Edward, et al.. (1989). Prenatal diagnosis and heterozygote detection by DNA analysis in ornithine transcarbamylase deficiency. The Journal of Pediatrics. 114(4). 582–588. 20 indexed citations
18.
Kerem, Batsheva, Johanna M. Rommens, Lap-Chee Tsui, et al.. (1989). DNA amplification for detection of the XV-2c polymorphism linked to cystic fibrosis. Nucleic Acids Research. 17(17). 7117–7117. 43 indexed citations
19.
O’Brien, William E., et al.. (1978). Carrier detection in ornithine transcarbamylase deficiency. The Journal of Pediatrics. 93(1). 75–78. 37 indexed citations
20.
Cook, George A., William E. O’Brien, Harland G. Wood, Michael King, & Richard L. Veech. (1978). A rapid, enzymatic assay for the measurement of inorganic pyrophosphate in animal tissues. Analytical Biochemistry. 91(2). 557–565. 38 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Kirby D. Smith Breakdown of academic impact, for papers by Yin‐Hsiu Chien Breakdown of academic impact, for papers by W E O'Brien Breakdown of academic impact, for papers by Marvin R. Natowicz Breakdown of academic impact, for papers by Brian Lake Breakdown of academic impact, for papers by Gail E. Herman Breakdown of academic impact, for papers by João Ramalho‐Santos Breakdown of academic impact, for papers by Jean Michaud Breakdown of academic impact, for papers by Kari Majamaa Breakdown of academic impact, for papers by Jerome S. Handler
Rankless by CCL
2026