David W. Christianson

24.2k total citations · 4 hit papers
292 papers, 18.7k citations indexed

About

David W. Christianson is a scholar working on Molecular Biology, Pharmacology and Oncology. According to data from OpenAlex, David W. Christianson has authored 292 papers receiving a total of 18.7k indexed citations (citations by other indexed papers that have themselves been cited), including 205 papers in Molecular Biology, 76 papers in Pharmacology and 59 papers in Oncology. Recurrent topics in David W. Christianson's work include Plant biochemistry and biosynthesis (66 papers), Microbial Natural Products and Biosynthesis (59 papers) and Enzyme function and inhibition (52 papers). David W. Christianson is often cited by papers focused on Plant biochemistry and biosynthesis (66 papers), Microbial Natural Products and Biosynthesis (59 papers) and Enzyme function and inhibition (52 papers). David W. Christianson collaborates with scholars based in United States, Germany and United Kingdom. David W. Christianson's co-authors include Carol A. Fierke, William N. Lipscomb, David E. Cane, Richard Alexander, Satish K. Nair, Yang Hai, J. David Cox, Luigi Di Costanzo, Nicholas J. Porter and Charles A. Lesburg and has published in prestigious journals such as Nature, Science and Chemical Reviews.

In The Last Decade

David W. Christianson

287 papers receiving 18.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structural and Chemical Biology of Terpenoid Cyclases

2017 834 citations David W. Christianson profile →
Structural Biology and Chemistry of the Terpenoid Cyclases

2006 638 citations David W. Christianson profile →
Carboxypeptidase A

1989 496 citations David W. Christianson et al. profile →
Histone deacetylase 6 structure and molecular basis of catalysis and inhibition

2016 381 citations David W. Christianson et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David W. Christianson United States	75	13.6k	4.4k	3.4k	2.8k	1.5k	292	18.7k
Israel Silman Israel	76	12.1k 0.9×	11.6k 2.6×	5.2k 1.5×	624 0.2×	934 0.6×	267	24.3k
Ettore Novellino Italy	71	12.9k 0.9×	2.6k 0.6×	7.4k 2.2×	2.2k 0.8×	459 0.3×	820	27.5k
Peter Wipf United States	84	12.4k 0.9×	2.1k 0.5×	13.0k 3.8×	1.7k 0.6×	530 0.3×	616	26.7k
T.L. Poulos United States	75	13.0k 1.0×	1.3k 0.3×	2.2k 0.7×	2.6k 0.9×	1.1k 0.7×	338	25.1k
Wilfred A. van der Donk United States	73	13.6k 1.0×	6.3k 1.4×	4.5k 1.3×	1.7k 0.6×	758 0.5×	345	19.8k
Dale L. Boger United States	92	14.6k 1.1×	8.1k 1.8×	20.4k 6.0×	2.2k 0.8×	999 0.7×	639	34.2k
John A. Katzenellenbogen United States	90	12.0k 0.9×	1.9k 0.4×	7.5k 2.2×	5.8k 2.1×	335 0.2×	629	33.8k
Masaki Otagiri Japan	58	9.7k 0.7×	1.1k 0.3×	1.5k 0.5×	3.9k 1.4×	651 0.4×	601	18.7k
Alan P. Kozikowski United States	76	12.4k 0.9×	2.8k 0.6×	9.1k 2.7×	3.1k 1.1×	388 0.3×	567	23.3k
Andrea Mattevi Italy	69	10.0k 0.7×	1.6k 0.4×	2.3k 0.7×	345 0.1×	2.4k 1.6×	236	15.4k

Countries citing papers authored by David W. Christianson

Since Specialization

Citations

This map shows the geographic impact of David W. Christianson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David W. Christianson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David W. Christianson more than expected).

Fields of papers citing papers by David W. Christianson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David W. Christianson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David W. Christianson. The network helps show where David W. Christianson may publish in the future.

Co-authorship network of co-authors of David W. Christianson

This figure shows the co-authorship network connecting the top 25 collaborators of David W. Christianson. A scholar is included among the top collaborators of David W. Christianson based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David W. Christianson. David W. Christianson is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Christianson, David W., et al.. (2025). Mechanism-Based Inhibition of Histone Deacetylase 6 by a Selenocyanate Is Subject to Redox Modulation. Journal of the American Chemical Society. 147(8). 6373–6377. 1 indexed citations

Watson, P. R., Jingyu Li, Laís Pessanha de Carvalho, et al.. (2025). Exploring Alternative Zinc-Binding Groups in Histone Deacetylase (HDAC) Inhibitors Uncovers DS-103 as a Potent Ethylhydrazide-Based HDAC Inhibitor with Chemosensitizing Properties. Journal of Medicinal Chemistry. 68(4). 4426–4452. 5 indexed citations

Christianson, David W., et al.. (2024). Structure and Function of Sabinene Synthase, a Monoterpene Cyclase That Generates a Highly Strained [3.1.0] Bicyclic Product. Biochemistry. 63(23). 3147–3159.

Watson, P. R., et al.. (2023). Macrocyclic Octapeptide Binding and Inferences on Protein Substrate Binding to Histone Deacetylase 6. ACS Chemical Biology. 18(4). 959–968. 3 indexed citations

Christianson, David W., Scott C. Seaman, Luyuan Li, et al.. (2023). The Adjustable Cranial Plate: A Novel Implant Designed to Eliminate the Need for Cranioplasty Surgery Following a Hemicraniectomy Operation. World Neurosurgery. 173. e306–e320. 1 indexed citations

Herp, Daniel, Johannes Ridinger, Dina Robaa, et al.. (2022). First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement**. ChemBioChem. 23(14). e202200180–e202200180. 18 indexed citations

Watson, P. R., et al.. (2022). Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6. Biochemistry. 61(18). 1945–1954. 5 indexed citations

Reßing, Nina, P. R. Watson, Andrea Schöler, et al.. (2022). Development of Fluorinated Peptoid-Based Histone Deacetylase (HDAC) Inhibitors for Therapy-Resistant Acute Leukemia. Journal of Medicinal Chemistry. 65(22). 15457–15472. 17 indexed citations

Hosseinzadeh, Parisa, P. R. Watson, Timothy W. Craven, et al.. (2021). Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites. Nature Communications. 12(1). 3384–3384. 45 indexed citations

10.

Ronnebaum, Trey A., Kushol Gupta, & David W. Christianson. (2020). Higher-order oligomerization of a chimeric αβγ bifunctional diterpene synthase with prenyltransferase and class II cyclase activities is concentration-dependent. Journal of Structural Biology. 210(1). 107463–107463. 14 indexed citations

11.

He, Haibing, Guangkai Bian, Corey J. Herbst‐Gervasoni, et al.. (2020). Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases. Nature Communications. 11(1). 3958–3958. 37 indexed citations

12.

Porter, Nicholas J. & David W. Christianson. (2019). Preparation of a new construct of human histone deacetylase 8 for the crystallization of enzyme-inhibitor complexes. Methods in enzymology on CD-ROM/Methods in enzymology. 626. 561–585. 2 indexed citations

13.

Senger, Johanna, Daniel Herp, Martin Marek, et al.. (2019). Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors. Journal of Medicinal Chemistry. 62(3). 1138–1166. 77 indexed citations

14.

Bhatia, Sanil, M. Groll, J.D. Osko, et al.. (2018). Discovery of the First-in-Class Dual Histone Deacetylase–Proteasome Inhibitor. Journal of Medicinal Chemistry. 61(22). 10299–10309. 62 indexed citations

15.

Decroos, Christophe, et al.. (2016). General Base–General Acid Catalysis in Human Histone Deacetylase 8. Biochemistry. 55(5). 820–832. 54 indexed citations

16.

Herbert, De’Broski R., Tatyana Orekov, Monica Ilies, et al.. (2010). Arginase I Suppresses IL-12/IL-23p40–Driven Intestinal Inflammation during Acute Schistosomiasis. The Journal of Immunology. 184(11). 6438–6446. 106 indexed citations

17.

Kim, Noel N., David W. Christianson, & Abdulmaged M. Traish. (2004). Role of Arginase in the Male and Female Sexual Arousal Response. Journal of Nutrition. 134(10). 2873S–2879S. 30 indexed citations

18.

Whittington, Douglas A., Mitchell L. Wise, Marek Urbanský, et al.. (2002). Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase. Proceedings of the National Academy of Sciences. 99(24). 15375–15380. 273 indexed citations

19.

Grzybowski, Bartosz A., Alexey Ishchenko, Chu‐Young Kim, et al.. (2002). Combinatorial computational method gives new picomolar ligands for a known enzyme. Proceedings of the National Academy of Sciences. 99(3). 1270–1273. 53 indexed citations

20.

Christianson, David W., J. David Cox, Noel N. Kim, & Abdulmaged M. Traish. (1999). Arginase-boronic acid complex highlights a physiological role in erectile function.. Nature Structural Biology. 6(11). 1043–1047. 138 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact