William C. Sha

9.6k total citations · 4 hit papers
39 papers, 8.2k citations indexed

About

William C. Sha is a scholar working on Immunology, Cancer Research and Molecular Biology. According to data from OpenAlex, William C. Sha has authored 39 papers receiving a total of 8.2k indexed citations (citations by other indexed papers that have themselves been cited), including 35 papers in Immunology, 13 papers in Cancer Research and 10 papers in Molecular Biology. Recurrent topics in William C. Sha's work include T-cell and B-cell Immunology (19 papers), Immunotherapy and Immune Responses (14 papers) and Immune Cell Function and Interaction (13 papers). William C. Sha is often cited by papers focused on T-cell and B-cell Immunology (19 papers), Immunotherapy and Immune Responses (14 papers) and Immune Cell Function and Interaction (13 papers). William C. Sha collaborates with scholars based in United States, Australia and Japan. William C. Sha's co-authors include David Baltimore, Amer A. Beg, Sankar Ghosh, Roderick T. Bronson, Dennis Y. Loh, Elaine Tuomanen, Hsiou-Chi Liou, Rodney D. Newberry, John H. Russell and Christopher A. Nelson and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

William C. Sha

39 papers receiving 8.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1995 1.6k citations Amer A. Beg, William C. Sha et al. Nature profile →
Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses

1995 982 citations William C. Sha, Hsiou-Chi Liou et al. Cell profile →
Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

1998 656 citations Wenjun Ouyang, Sheila Ranganath et al. Immunity profile →
Positive and negative selection of an antigen receptor on T cells in transgenic mice

1988 649 citations William C. Sha, Christopher A. Nelson et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
William C. Sha United States	30	6.0k	3.0k	2.3k	1.7k	486	39	8.2k
Hailing Hsu United States	17	4.2k 0.7×	3.1k 1.0×	4.8k 2.1×	1.7k 1.0×	367 0.8×	23	8.3k
Arda Shahinian Canada	29	6.3k 1.0×	1.5k 0.5×	3.4k 1.5×	1.8k 1.1×	536 1.1×	38	9.4k
Louise Carlson United States	35	2.8k 0.5×	2.0k 0.7×	3.0k 1.3×	1.5k 0.9×	339 0.7×	60	5.9k
Nils Holler Switzerland	20	3.9k 0.6×	1.5k 0.5×	5.0k 2.2×	1.1k 0.7×	325 0.7×	20	8.3k
Jean-Luc Bodmer Switzerland	23	4.3k 0.7×	2.0k 0.7×	6.0k 2.6×	1.5k 0.9×	436 0.9×	31	8.7k
Michael David United States	46	4.2k 0.7×	1.6k 0.5×	4.1k 1.8×	3.3k 2.0×	484 1.0×	83	8.6k
M Shannon Australia	40	2.5k 0.4×	1.9k 0.6×	2.9k 1.3×	1.4k 0.8×	428 0.9×	83	5.8k
Michael Hahne France	41	5.5k 0.9×	1.7k 0.6×	5.9k 2.6×	2.1k 1.3×	621 1.3×	96	10.6k
D Metcalf Australia	35	4.4k 0.7×	990 0.3×	2.0k 0.9×	3.0k 1.8×	848 1.7×	72	8.1k
Ken Schooley United States	15	3.3k 0.6×	913 0.3×	3.3k 1.5×	996 0.6×	391 0.8×	17	6.5k

Countries citing papers authored by William C. Sha

Since Specialization

Citations

This map shows the geographic impact of William C. Sha's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William C. Sha with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William C. Sha more than expected).

Fields of papers citing papers by William C. Sha

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William C. Sha. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William C. Sha. The network helps show where William C. Sha may publish in the future.

Co-authorship network of co-authors of William C. Sha

This figure shows the co-authorship network connecting the top 25 collaborators of William C. Sha. A scholar is included among the top collaborators of William C. Sha based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William C. Sha. William C. Sha is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bakkour, Sonia & William C. Sha. (2008). Mapping of the ICOS binding surface of murine B7h using an unbiased, cellular library of B7h mutants created by cyclical packaging rescue. Journal of Immunological Methods. 332(1-2). 151–161. 1 indexed citations

Bhattacharya, Deepta, Christopher B. Franco, Naoki Hosen, et al.. (2007). Transcriptional Profiling of Antigen-Dependent Murine B Cell Differentiation and Memory Formation. The Journal of Immunology. 179(10). 6808–6819. 134 indexed citations

Logue, Eric C., Sonia Bakkour, Michael Murphy, Hector Nolla, & William C. Sha. (2006). ICOS-Induced B7h Shedding on B Cells Is Inhibited by TLR7/8 and TLR9. The Journal of Immunology. 177(4). 2356–2364. 29 indexed citations

Liang, Linda, et al.. (2002). Constitutive Expression of the B7h Ligand for Inducible Costimulator on Naive B Cells Is Extinguished after Activation by Distinct B Cell Receptor and Interleukin 4 Receptor–mediated Pathways and Can Be Rescued by CD40 Signaling. The Journal of Experimental Medicine. 196(1). 97–108. 72 indexed citations

Liang, Linda & William C. Sha. (2002). The right place at the right time: novel B7 family members regulate effector T cell responses. Current Opinion in Immunology. 14(3). 384–390. 92 indexed citations

Wallin, Jeffrey J., et al.. (2001). Enhancement of CD8+ T Cell Responses by ICOS/B7h Costimulation. The Journal of Immunology. 167(1). 132–139. 132 indexed citations

Ouyang, Wenjun, Sheila Ranganath, Deepta Bhattacharya, et al.. (1998). Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism. Immunity. 9(5). 745–755. 656 indexed citations breakdown →

Ranganath, Sheila, Wenjun Ouyang, William C. Sha, et al.. (1998). Cutting Edge: GATA-3-Dependent Enhancer Activity in IL-4 Gene Regulation. The Journal of Immunology. 161(8). 3822–3826. 155 indexed citations

Weih, Falk, Stephen K. Durham, D S Barton, et al.. (1997). p50–NF-κB Complexes Partially Compensate for the Absence of RelB: Severely Increased Pathology in p50−/−relB−/−Double-knockout Mice. The Journal of Experimental Medicine. 185(7). 1359–1370. 97 indexed citations

10.

Weih, Falk, Stephen K. Durham, D S Barton, et al.. (1996). Both multiorgan inflammation and myeloid hyperplasia in RelB-deficient mice are T cell dependent. The Journal of Immunology. 157(9). 3974–3979. 69 indexed citations

11.

Spellerberg, Barbara, Carsten Rosenow, William C. Sha, & Elaine Tuomanen. (1996). Pneumococcal cell wall activates NF-κB in human monocytes: aspects distinct from endotoxin. Microbial Pathogenesis. 20(5). 309–317. 28 indexed citations

12.

Sha, William C., Hsiou-Chi Liou, Elaine Tuomanen, & David Baltimore. (1995). Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses. Cell. 80(2). 321–330. 982 indexed citations breakdown →

13.

Beg, Amer A., William C. Sha, Roderick T. Bronson, Sankar Ghosh, & David Baltimore. (1995). Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB. Nature. 376(6536). 167–170. 1563 indexed citations breakdown →

14.

Beg, Amer A., William C. Sha, Rod T. Bronson, & David Baltimore. (1995). Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice.. Genes & Development. 9(22). 2736–2746. 397 indexed citations

15.

Fung‐Leung, Wai‐Ping, Valerie A. Wallace, Dawn Gray, et al.. (1993). CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny. European Journal of Immunology. 23(1). 212–216. 61 indexed citations

16.

Robey, Ellen A., Fred Ramsdell, Dimitris Kioussis, et al.. (1992). The level of CD8 expression can determine the outcome of thymic selection. Cell. 69(7). 1089–1096. 123 indexed citations

17.

Loh, Dennis Y., William C. Sha, C A Nelson, et al.. (1989). Positive and Negative Selection of T Lymphocytes. Cold Spring Harbor Symposia on Quantitative Biology. 54(0). 147–151. 7 indexed citations

18.

Sha, William C., Christopher A. Nelson, Rodney D. Newberry, et al.. (1988). Positive and negative selection of an antigen receptor on T cells in transgenic mice. Nature. 336(6194). 73–76. 649 indexed citations breakdown →

19.

Sha, William C., et al.. (1988). Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice. Nature. 335(6187). 271–274. 442 indexed citations

20.

Behlke, Mark A., Dominic G. Spinella, Hubert S. Chou, et al.. (1985). T-Cell Receptor β-Chain Expression: Dependence on Relatively Few Variable Region Genes. Science. 229(4713). 566–570. 176 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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