William C. Hines

2.7k total citations · 1 hit paper
29 papers, 2.0k citations indexed

About

William C. Hines is a scholar working on Molecular Biology, Oncology and Physiology. According to data from OpenAlex, William C. Hines has authored 29 papers receiving a total of 2.0k indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 15 papers in Oncology and 9 papers in Physiology. Recurrent topics in William C. Hines's work include Cancer Cells and Metastasis (11 papers), Telomeres, Telomerase, and Senescence (8 papers) and Epigenetics and DNA Methylation (5 papers). William C. Hines is often cited by papers focused on Cancer Cells and Metastasis (11 papers), Telomeres, Telomerase, and Senescence (8 papers) and Epigenetics and DNA Methylation (5 papers). William C. Hines collaborates with scholars based in United States, Switzerland and Argentina. William C. Hines's co-authors include Mina J. Bissell, Paul Yaswen, Audrey Brenot, Zena Werb, Andrew J. Ewald, Kevin J. Cheung, Ryan S. Gray, Eliah R. Shamir, Jeffrey K. Griffith and Marco Bisoffi and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Medicine.

In The Last Decade

William C. Hines

29 papers receiving 2.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

2011 1.1k citations Mina J. Bissell, William C. Hines Nature Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
William C. Hines United States	17	927	920	495	442	319	29	2.0k
Evanthia T. Roussos Torres United States	18	1.1k 1.2×	1.1k 1.1×	413 0.8×	513 1.2×	379 1.2×	62	2.4k
René Villadsen Denmark	23	1.6k 1.7×	1.3k 1.4×	605 1.2×	347 0.8×	267 0.8×	40	2.5k
Ana Cerezo Spain	13	841 0.9×	1.1k 1.2×	358 0.7×	677 1.5×	138 0.4×	16	2.0k
Fernando Calvo Spain	22	1.0k 1.1×	1.8k 1.9×	467 0.9×	1.1k 2.5×	217 0.7×	42	2.9k
Roya Navab Canada	25	694 0.7×	1.1k 1.2×	638 1.3×	237 0.5×	173 0.5×	46	2.0k
Sebastian Hoersch United States	16	672 0.7×	1.6k 1.7×	503 1.0×	350 0.8×	144 0.5×	23	2.6k
Daniela Tosoni Italy	16	1.2k 1.3×	1.8k 1.9×	531 1.1×	585 1.3×	99 0.3×	24	2.7k
Olav Engebraaten Norway	29	925 1.0×	1.3k 1.4×	700 1.4×	277 0.6×	230 0.7×	87	2.7k
Anthony R. Howlett United States	21	1.0k 1.1×	1.3k 1.4×	369 0.7×	521 1.2×	419 1.3×	34	2.5k
Maria‐Carla Parrini France	6	1.1k 1.2×	1.2k 1.3×	459 0.9×	442 1.0×	141 0.4×	7	2.2k

Countries citing papers authored by William C. Hines

Since Specialization

Citations

This map shows the geographic impact of William C. Hines's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William C. Hines with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William C. Hines more than expected).

Fields of papers citing papers by William C. Hines

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William C. Hines. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William C. Hines. The network helps show where William C. Hines may publish in the future.

Co-authorship network of co-authors of William C. Hines

This figure shows the co-authorship network connecting the top 25 collaborators of William C. Hines. A scholar is included among the top collaborators of William C. Hines based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William C. Hines. William C. Hines is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Sayaman, Rosalyn W., et al.. (2024). Transcriptomic analysis of the 12 major human breast cell types reveals mechanisms of cell and tissue function. PLoS Biology. 22(11). e3002820–e3002820. 2 indexed citations

Crabtree, William, et al.. (2024). Breast pericytes: a newly identified driver of tumor cell proliferation. Frontiers in Oncology. 14. 1455484–1455484. 1 indexed citations

Hines, William C.. (2023). Lost in transduction: Critical considerations when using viral vectors. Frontiers in Cell and Developmental Biology. 10. 1080265–1080265. 1 indexed citations

Wang, Chunqing, Xing Zhang, Liping Luo, et al.. (2022). COX-2 Deficiency Promotes White Adipogenesis via PGE2-Mediated Paracrine Mechanism and Exacerbates Diet-Induced Obesity. Cells. 11(11). 1819–1819. 16 indexed citations

Foulke‐Abel, Jennifer, et al.. (2022). Ulcerative Colitis: Novel Epithelial Insights Provided by Single Cell RNA Sequencing. Frontiers in Medicine. 9. 868508–868508. 13 indexed citations

Hines, William C., Irene Kuhn, James C. Garbe, et al.. (2015). 184AA3: a xenograft model of ER+ breast adenocarcinoma. Breast Cancer Research and Treatment. 155(1). 37–52. 7 indexed citations

Hines, William C., Paul Yaswen, & Mina J. Bissell. (2015). Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias. Nature Communications. 6(1). 6927–6927. 24 indexed citations

Hines, William C., et al.. (2014). Sorting Out the FACS: A Devil in the Details. Cell Reports. 6(5). 779–781. 62 indexed citations

Pirone, Jason R., Monica D’Arcy, Delisha A. Stewart, et al.. (2012). Age-Associated Gene Expression in Normal Breast Tissue Mirrors Qualitative Age-at-Incidence Patterns for Breast Cancer. Cancer Epidemiology Biomarkers & Prevention. 21(10). 1735–1744. 35 indexed citations

10.

Bazarov, Alexey V., Won Jae Lee, William C. Hines, et al.. (2012). The specific role of pRb in p16^INK4A-mediated arrest of normal and malignant human breast cells. Cell Cycle. 11(5). 1008–1013. 20 indexed citations

11.

Cheung, Kevin J., Audrey Brenot, Eliah R. Shamir, et al.. (2012). ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium. Proceedings of the National Academy of Sciences. 109(39). E2595–604. 350 indexed citations

12.

Trujillo, Kristina A., et al.. (2011). Breast Field Cancerization: Isolation and Comparison of Telomerase-Expressing Cells in Tumor and Tumor Adjacent, Histologically Normal Breast Tissue. Molecular Cancer Research. 9(9). 1209–1221. 21 indexed citations

13.

Bissell, Mina J. & William C. Hines. (2011). Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression. Nature Medicine. 17(3). 320–329. 1134 indexed citations breakdown →

14.

Mukhopadhyay, Rituparna, Sylvain V. Costes, Alexey V. Bazarov, et al.. (2010). Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies. Breast Cancer Research. 12(1). R11–R11. 19 indexed citations

15.

Hines, William C., Alexey V. Bazarov, Rituparna Mukhopadhyay, & Paul Yaswen. (2010). BORIS (CTCFL) Is Not Expressed in Most Human Breast Cell Lines and High Grade Breast Carcinomas. PLoS ONE. 5(3). e9738–e9738. 19 indexed citations

16.

Bazarov, Alexey V., Marjolein van Sluis, William C. Hines, et al.. (2010). p16^INK4a‐mediated suppression of telomerase in normal and malignant human breast cells. Aging Cell. 9(5). 736–746. 19 indexed citations

17.

Bazarov, Alexey V., et al.. (2009). Telomerase activation by c-Myc in human mammary epithelial cells requires additional genomic changes. Cell Cycle. 8(20). 3373–3378. 16 indexed citations

18.

Heaphy, Christopher M., William C. Hines, Kimberly S. Butler, et al.. (2007). Assessment of the Frequency of Allelic Imbalance in Human Tissue Using a Multiplex Polymerase Chain Reaction System. Journal of Molecular Diagnostics. 9(2). 266–271. 5 indexed citations

19.

Heaphy, Christopher M., Marco Bisoffi, Colleen Fordyce, et al.. (2006). Telomere DNA content and allelic imbalance demonstrate field cancerization in histologically normal tissue adjacent to breast tumors. International Journal of Cancer. 119(1). 108–116. 67 indexed citations

20.

Hines, William C., et al.. (2006). Protease nexin-1 expression is altered in human breast cancer. Cancer Cell International. 6(1). 16–16. 22 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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