H. Steuber

2.3k citations

38 papers · 1.3k indexed · h-index 22

Impact in

Cell Biology top 5%
- Aldose Reductase and Taurine
Computational Theory and Mathematics top 2%
- Computational Drug Discovery Methods

Papers in ⓘ

Cell Biology 11
- Aldose Reductase and Taurine 11
Computational Theory and Mathematics 6
- Computational Drug Discovery Methods 6

Co-authors: G. Klebe (15 shared papers)A. Heine (10 shared papers)Matthias Zentgraf (6 shared papers)Christoph Sotriffer (6 shared papers)Wibke E. Diederich (7 shared papers)A. Podjarny (3 shared papers)Rolf Hilgenfeld (1 shared paper)Christof Gerlach (3 shared papers)
Journals: Journal of Molecular Biology (6 papers)Angewandte Chemie International Edition (5 papers)Journal of Medicinal Chemistry (5 papers)ChemMedChem (4 papers)Current Topics in Medicinal Chemistry (1 paper)
Partner nations: Germany United States Italy

In The Last Decade

H. Steuber

38 papers receiving 1.3k citations

Peers

Countries citing papers authored by H. Steuber

Since Specialization

Citations

This map shows the geographic impact of H. Steuber's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by H. Steuber with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites H. Steuber more than expected).

Fields of papers citing papers by H. Steuber

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by H. Steuber. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by H. Steuber. The network helps show where H. Steuber may publish in the future.

Co-authors

The 25 scholars most cited alongside H. Steuber, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with H. Steuber Line = papers co-authored together H. Steuber links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 38 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Novel Dengue Virus NS2B/NS3 Protease Inhibitors Antimicrobial Agents and Chemotherapy ·Hongmei Wu, Stefanie Böck, Mariya Snitko, Thilo Berger, Thomas Weidner, Steven A. Holloway, Manuel Kanitz, Wibke E. Diederich, H. Steuber, Christof Walter, Daniela Hofmann, Benedikt Weißbrich, Ralf Spannaus, Eliana G. Acosta, Ralf Bartenschlager, Bernd Engels, Tanja Schirmeister, Jochen Bodem	2014	123
2	Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions Journal of Molecular Biology ·H. Steuber, Matthias Zentgraf, Christof Gerlach, Christoph Sotriffer, A. Heine, G. Klebe	2006	93
3	The E. coli Effector Protein NleF Is a Caspase Inhibitor PLoS ONE ·Sonja Blasche, Mario Mörtl, H. Steuber, Gabriella Siszler, Shahista Nisa, Frank Schwarz, Inna N. Lavrik, Thomas M. A. Gronewold, K. Maskos, Michael S. Donnenberg, Dirk Ullmann, Peter Uetz, Manfred Kögl	2013	78
4	A combined spectroscopic and crystallographic approach to probing drug–human serum albumin interactions Bioorganic & Medicinal Chemistry ·David Buttar, Nicola Colclough, S. Gerhardt, Philip A. MacFaul, Scott Phillips, Alleyn T. Plowright, Paul R. O. Whittamore, Kin Yip Tam, K. Maskos, Stefan Steinbacher, H. Steuber	2010	74
5	Xanthomonins I–III: A New Class of Lasso Peptides with a Seven‐Residue Macrolactam Ring Angewandte Chemie International Edition ·Julian D. Hegemann, Marcel Zimmermann, Shaozhou Zhu, H. Steuber, Klaus Harms, Xiulan Xie, Mohamed A. Marahiel	2014	69
6	Structural and Thermodynamic Study on Aldose Reductase: Nitro-substituted Inhibitors with Strong Enthalpic Binding Contribution Journal of Molecular Biology ·H. Steuber, A. Heine, G. Klebe	2006	69
7	Evolution of Flavone Synthase I from Parsley Flavanone 3β-Hydroxylase by Site-Directed Mutagenesis PLANT PHYSIOLOGY ·Yvonne Helen Gebhardt, Simone Witte, H. Steuber, Ulrich Matern, Stefan Martens	2007	65
8	Darolutamide is a potent androgen receptor antagonist with strong efficacy in prostate cancer models International Journal of Cancer ·Tatsuo Sugawara, Simon J. Baumgart, Ekaterina Nevedomskaya, Kristin Reichert, H. Steuber, Pascale Lejeune, Dominik Mumberg, Bernard Haendler	2019	61
9	How Reliable Are Current Docking Approaches for Structure‐Based Drug Design? Lessons from Aldose Reductase Angewandte Chemie International Edition ·Matthias Zentgraf, H. Steuber, C. Koch, Concettina La Motta, Stefania Sartini, Christoph Sotriffer, G. Klebe	2007	54
10	An Organometallic Inhibitor for the Human Repair Enzyme 7,8‐Dihydro‐8‐oxoguanosine Triphosphatase Angewandte Chemie International Edition ·M. Streib, Katja Kräling, Kristin Richter, Xiulan Xie, H. Steuber, Eric Meggers	2013	51
11	Merging the Binding Sites of Aldose and Aldehyde Reductase for Detection of Inhibitor Selectivity-determining Features Journal of Molecular Biology ·H. Steuber, A. Heine, A. Podjarny, G. Klebe	2008	48
12	Recent Advances in Targeting Viral Proteases for the Discovery of Novel Antivirals Current Topics in Medicinal Chemistry ·H. Steuber, Rolf Hilgenfeld	2010	45
13	High-resolution Crystal Structure of Aldose Reductase Complexed with the Novel Sulfonyl-pyridazinone Inhibitor Exhibiting an Alternative Active Site Anchoring Group Journal of Molecular Biology ·H. Steuber, Matthias Zentgraf, A. Podjarny, A. Heine, G. Klebe	2005	45
14	Factorizing Selectivity Determinants of Inhibitor Binding toward Aldose and Aldehyde Reductases: Structural and Thermodynamic Properties of the Aldose Reductase Mutant Leu300Pro−Fidarestat Complex Journal of Medicinal Chemistry ·T. Petrova, H. Steuber, Isabelle Hazemann, A. Cousido-Siah, A. Mitschler, Roland P.‐T. Chung, Mitsuru Oka, G. Klebe, Ossama El‐Kabbani, A. Joachimiak, A. Podjarny	2005	45
15	Evidence for a Novel Binding Site Conformer of Aldose Reductase in Ligand-Bound State Journal of Molecular Biology ·H. Steuber, Matthias Zentgraf, Concettina La Motta, Stefania Sartini, A. Heine, G. Klebe	2007	34
16	Structural Hot Spots Determine Functional Diversity of the Candida glabrata Epithelial Adhesin Family Journal of Biological Chemistry ·R. Diderrich, Michael Andreas Kock, Manuel Maestre‐Reyna, Petra Keller, H. Steuber, Steffen Rupp, Lars‐Oliver Essen, Hans‐Ulrich Mösch	2015	33
17	Tracing Changes in Protonation: A Prerequisite to Factorize Thermodynamic Data of Inhibitor Binding to Aldose Reductase Journal of Molecular Biology ·H. Steuber, Paul Czodrowski, Christoph Sotriffer, G. Klebe	2007	33
18	Privileged Structures Meet Human T-Cell Leukemia Virus-1 (HTLV-1): C₂-Symmetric 3,4-Disubstituted Pyrrolidines as Nonpeptidic HTLV-1 Protease Inhibitors Journal of Medicinal Chemistry ·Maren Kuhnert, Andreas Blum, H. Steuber, Wibke E. Diederich	2015	30
19	Thermodynamic Inhibition Profile of a Cyclopentyl and a Cyclohexyl Derivative towards Thrombin: The Same but for Different Reasons Angewandte Chemie International Edition ·Christof Gerlach, Michael Smolinski, H. Steuber, Christoph Sotriffer, A. Heine, David Hangauer, G. Klebe	2007	28
20	Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor Journal of Medicinal Chemistry ·Renato Ferreira de Freitas, Mohammad S. Eram, Magdalena M. Szewczyk, H. Steuber, David Smil, Hong Wu, Fengling Li, Guillermo Senisterra, Aiping Dong, Peter J. Brown, Marion Hitchcock, Dieter Moosmayer, Christian M. Stegmann, Ursula Egner, C.H. Arrowsmith, Dalia Baršytė-Lovejoy, Masoud Vedadi, Matthieu Schapira	2016	28

About H. Steuber

H. Steuber is a scholar working on Cell Biology, Computational Theory and Mathematics, Molecular Biology, Pharmacology and Oncology, having authored 38 papers that have together received 1.3k indexed citations. Recurring topics across this work include Aldose Reductase and Taurine (11 papers), Computational Drug Discovery Methods (6 papers), Chemical Synthesis and Analysis (5 papers), Enzyme Structure and Function (5 papers), Metal complexes synthesis and properties (5 papers), Protein Structure and Dynamics (4 papers), Biochemical and Molecular Research (4 papers) and Free Radicals and Antioxidants (3 papers). The work is most often cited by research in Cell Biology (238 citations), Computational Theory and Mathematics (208 citations), Endocrinology (54 citations), Molecular Biology (723 citations) and Pharmacology (139 citations). H. Steuber has collaborated with scholars based in Germany, United States and Italy. Frequent co-authors include G. Klebe, A. Heine, Matthias Zentgraf, Christoph Sotriffer, Wibke E. Diederich, A. Podjarny, Rolf Hilgenfeld, Christof Gerlach, Xiulan Xie and Stefania Sartini. Their work appears in journals such as Journal of Molecular Biology, Angewandte Chemie International Edition, Journal of Medicinal Chemistry, ChemMedChem and Current Topics in Medicinal Chemistry.

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