Werner Risau

46.9k total citations · 18 hit papers
149 papers, 38.3k citations indexed

About

Werner Risau is a scholar working on Molecular Biology, Cancer Research and Neurology. According to data from OpenAlex, Werner Risau has authored 149 papers receiving a total of 38.3k indexed citations (citations by other indexed papers that have themselves been cited), including 118 papers in Molecular Biology, 32 papers in Cancer Research and 27 papers in Neurology. Recurrent topics in Werner Risau's work include Angiogenesis and VEGF in Cancer (77 papers), Cancer, Hypoxia, and Metabolism (26 papers) and Barrier Structure and Function Studies (26 papers). Werner Risau is often cited by papers focused on Angiogenesis and VEGF in Cancer (77 papers), Cancer, Hypoxia, and Metabolism (26 papers) and Barrier Structure and Function Studies (26 papers). Werner Risau collaborates with scholars based in Germany, United States and France. Werner Risau's co-authors include Georg Breier, Karl H. Plate, Ingo Flamme, Herbert A. Weich, Hartwig Wolburg, Urban Deutsch, Harald Schnürch, B Millauer, Ursula Albrecht and Hugo H. Marti and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Werner Risau

149 papers receiving 37.3k citations

Hit Papers

Mechanisms of angiogenesis 1987 2026 2000 2013 1997 1996 1992 1993 1995 1000 2.0k 3.0k 4.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Mechanisms of angiogenesis
    1997 4.6k citations Werner Risau Nature profile →
  2. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    1996 3.2k citations Peter Carmeliet, Georg Breier et al. Nature profile →
  3. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
    1992 1.9k citations Karl H. Plate, Georg Breier et al. Nature profile →
  4. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
    1993 1.7k citations Harald Schnürch, Werner Risau et al. profile →
  5. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
    1995 1.4k citations Urban Deutsch, Hartwig Wolburg et al. Nature profile →
  6. Vasculogenesis
    1995 1.1k citations Werner Risau, Ingo Flamme profile →
  7. Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation
    1992 933 citations Georg Breier, Werner Risau et al. profile →
  8. SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types.
    1999 885 citations Werner Risau et al. PubMed profile →
  9. Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis
    1999 816 citations Urban Deutsch, Werner Risau et al. profile →
  10. The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities
    1996 723 citations Matthias Clauss, Georg Breier et al. profile →
  11. Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor
    1989 619 citations Hannes C. A. Drexler, Werner Risau et al. Nature profile →
  12. Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.
    1987 585 citations Werner Risau et al. profile →
  13. Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells
    1998 573 citations Werner Risau et al. profile →
  14. Hypoxia-Induced Vascular Endothelial Growth Factor Expression Precedes Neovascularization after Cerebral Ischemia
    2000 573 citations Werner Risau et al. profile →
  15. Role of tissue factor in embryonic blood vessel development
    1996 541 citations Peter Carmeliet, Nigel Mackman et al. Nature profile →
  16. Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies
    1988 518 citations Werner Risau et al. profile →
  17. Hypoxia-induced Transcriptional Activation and Increased mRNA Stability of Vascular Endothelial Growth Factor in C6 Glioma Cells
    1995 508 citations Marc G. Achen, Georg Breier et al. profile →
  18. Vascular Endothelial Growth Factor Induces Endothelial Fenestrations In Vitro
    1998 503 citations Hartwig Wolburg, Georg Breier et al. profile →

Peers

Werner Risau
Lena Claesson‐Welsh Sweden
Michael Klagsbrun United States
Christer Betsholtz Sweden
Bengt Westermark Sweden
Paolo M. Comoglio Italy
Carl‐Henrik Heldin Sweden
Jeffrey L. Wrana Canada
Kohei Miyazono Japan
Elisabetta Dejana Italy
Walter Birchmeier Germany
Lena Claesson‐Welsh Sweden
Werner Risau
Citations per year, relative to Werner Risau Werner Risau (= 1×) peers Lena Claesson‐Welsh

Countries citing papers authored by Werner Risau

Since Specialization
Citations

This map shows the geographic impact of Werner Risau's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Werner Risau with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Werner Risau more than expected).

Fields of papers citing papers by Werner Risau

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Werner Risau. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Werner Risau. The network helps show where Werner Risau may publish in the future.

Co-authorship network of co-authors of Werner Risau

This figure shows the co-authorship network connecting the top 25 collaborators of Werner Risau. A scholar is included among the top collaborators of Werner Risau based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Werner Risau. Werner Risau is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Stratmann, A., Till Acker, Angelika M. Burger, et al.. (2001). Differential inhibition of tumor angiogenesis by tie2 and vascular endothelial growth factor receptor‐2 dominant‐negative receptor mutants. International Journal of Cancer. 91(3). 273–282. 68 indexed citations
2.
Miller, Diane, et al.. (1999). Hypoxic Regulation of Vascular Endothelial Growth Factor mRNA Stability Requires the Cooperation of Multiple RNA Elements. Molecular Biology of the Cell. 10(4). 907–919. 150 indexed citations
3.
Miller, Diane, et al.. (1998). The vascular endothelial growth factor mRNA contains an internal ribosome entry site. FEBS Letters. 434(3). 417–420. 72 indexed citations
4.
Yancopoulos, George D., et al.. (1998). Angiopoietin-1 induces sprouting angiogenesis in vitro. Current Biology. 8(9). 529–532. 386 indexed citations
5.
Takakura, Nobuyuki, Kunihiro Tsuchida, Hiroaki Kodama, et al.. (1997). Expressions ofPDGF receptor alpha, c‐KitandFlk1genes clustering in mouse chromosome 5 define distinct subsets of nascent mesodermal cells. Development Growth & Differentiation. 39(6). 729–740. 185 indexed citations
6.
Mayr, Thomas, Urban Deutsch, Michael Kühl, et al.. (1997). Fritz: a secreted frizzled-related protein that inhibits Wnt activity. Mechanisms of Development. 63(1). 109–125. 59 indexed citations
7.
8.
Pakkanen, Timo, Jukka Luoma, Saila Laakso, et al.. (1996). Local adventitial VEGF gene transfer reduces neointima formation in rabbit carotid arteries. UCL Discovery (University College London). 1 indexed citations
9.
Carmeliet, Peter, Nigel Mackman, Lieve Moons, et al.. (1996). Role of tissue factor in embryonic blood vessel development. Nature. 383(6595). 73–75. 541 indexed citations breakdown →
10.
Flamme, Ingo, Georg Breier, & Werner Risau. (1995). Vascular Endothelial Growth Factor (VEGF) and VEGF Receptor 2(flk-1) Are Expressed during Vasculogenesis and Vascular Differentiation in the Quail Embryo. Developmental Biology. 169(2). 699–712. 215 indexed citations
11.
Achen, Marc G., Matthias Clauss, Harald Schnürch, & Werner Risau. (1995). The non-receptor tyrosine kinase Lyn is localised in the developing murine blood-brain barrier. Differentiation. 59(1). 15–24. 20 indexed citations
12.
Engelhardt, Britta, et al.. (1994). Lysis of rat brain microvascular endothelial cells mediated by resting but not activated MBP-specific CD4+ T cell lines. Journal of Neuroimmunology. 55(1). 69–80. 5 indexed citations
13.
Kniesel, Uwe, Andreas Reichenbach, Werner Risau, & Hartwig Wolburg. (1994). Quantification of tight junction complexity by means of fractal analysis. Tissue and Cell. 26(6). 901–912. 11 indexed citations
14.
Risau, Werner. (1994). Molecular Biology of Blood-Brain Barrier Ontogenesis and Function. PubMed. 60. 109–112. 32 indexed citations
15.
Risau, Werner, Hannes C. A. Drexler, Vladimir Mironov, et al.. (1992). Platelet-Derived Growth Factor is AngiogenicIn Vivo. Growth Factors. 7(4). 261–266. 223 indexed citations
16.
17.
Risau, Werner & Hartwig Wolburg. (1990). Development of the blood-brain barrier. Trends in Neurosciences. 13(5). 174–178. 415 indexed citations
18.
Risau, Werner, et al.. (1988). Preferential expression of a 130,000-Da cell surface protein by vascular wall cells in vitro and in vivo. Microvascular Research. 35(3). 265–277. 1 indexed citations
19.
Roth, W.K., Sabine Werner, Werner Risau, K. Remberger, & P. H. Hofschneider. (1988). Cultured, aids‐related Kaposi's sarcoma cells express endothelial cell markers and are weakly malignant in vitro. International Journal of Cancer. 42(5). 767–773. 57 indexed citations
20.
Risau, Werner. (1987). Endothel, Angiogenese und Metastasierung. Oncology Research and Treatment. 10(4). 260–262. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Lena Claesson‐Welsh Breakdown of academic impact, for papers by Michael Klagsbrun Breakdown of academic impact, for papers by Christer Betsholtz Breakdown of academic impact, for papers by Bengt Westermark Breakdown of academic impact, for papers by Paolo M. Comoglio Breakdown of academic impact, for papers by Carl‐Henrik Heldin Breakdown of academic impact, for papers by Jeffrey L. Wrana Breakdown of academic impact, for papers by Kohei Miyazono Breakdown of academic impact, for papers by Elisabetta Dejana Breakdown of academic impact, for papers by Walter Birchmeier
Rankless by CCL
2026