Tooru Kimura

3.9k citations

109 papers · 3.0k indexed · h-index 33

Impact in

Organic Chemistry top 2%
- Click Chemistry and Applications
- Carbohydrate Chemistry and Synthesis
Virology top 5%

Papers in

Virology 19
- HIV Research and Treatment 19
Organic Chemistry 47
- Click Chemistry and Applications 18
- Carbohydrate Chemistry and Synthesis 13

Co-authors: Yoshiaki Kiso Yoshio Hayashi Youhei Sohma Koushi Hidaka Y. Hamada Masato Sasaki Mariusz Skwarczyński Atsuhiko Taniguchi
Journals: Bioorganic & Medicinal Chemistry Letters (25 papers)Bioorganic & Medicinal Chemistry (12 papers)Tetrahedron Letters (9 papers)Journal of Peptide Science (8 papers)Chemical and Pharmaceutical Bulletin (7 papers)
Partner nations: Japan United States China

In The Last Decade

Tooru Kimura

109 papers receiving 3.0k citations

Peers

Countries citing papers authored by Tooru Kimura

Since Specialization

Citations

This map shows the geographic impact of Tooru Kimura's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tooru Kimura with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tooru Kimura more than expected).

Fields of papers citing papers by Tooru Kimura

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tooru Kimura. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tooru Kimura. The network helps show where Tooru Kimura may publish in the future.

Co-authors

The 25 scholars most cited alongside Tooru Kimura, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tooru Kimura Line = papers co-authored together Tooru Kimura links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Maintaining potent HTLV-I protease inhibition without the P3-cap moiety in small tetrapeptidic inhibitors Bioorganic & Medicinal Chemistry Letters ·Jeffrey‐Tri Nguyen, Keiko Kato, Kimberly Sancho, Koushi Hidaka, Tooru Kimura, Yoshiaki Kiso	2011	7
2	Application of Intramolecular Migration Reaction in Peptide Chemistry to Chemical Biology, Chemical Pharmaceutics and Medicinal Chemistry Advances in experimental medicine and biology ·Yoshio Hayashi, Yuri Yamazaki, Mariusz Skwarczyński, Youhei Sohma, Atsuhiko Taniguchi, А. А. Гришкевич, Tooru Kimura, Saskia Neuteboom, Barbara C. M. Potts, Susha Dayanandan, Yoshiaki Kiso	2009	1
3	Inhibitory effect of a dimerization-arm-mimetic peptide on EGF receptor activation Bioorganic & Medicinal Chemistry Letters ·L. Waldron, Catherine A.M. Clarke, Taeko Kakizawa, Tooru Kimura, Shigeyuki Yokoyama, Yoshiaki Kiso, Kazuki Saito	2009	17
4	“Click Peptide“: pH‐Triggered in Situ Production and Aggregation of Monomer Aβ1–42 ChemBioChem ·Atsuhiko Taniguchi, Youhei Sohma, Amira Abdelrasoul, Hidehito Mukai, Tooru Kimura, Yoshio Hayashi, Katsumi Matsuzaki, Yoshiaki Kiso	2009	59
5	Synthesis and activity of tetrapeptidic HTLV-I protease inhibitors possessing different P3-cap moieties Bioorganic & Medicinal Chemistry ·Meihui Zhang, Jeffrey‐Tri Nguyen, Kimberly Sancho, Tooru Kimura, Maosheng Cheng, Yoshio Hayashi, Yoshiaki Kiso	2008	11
6	Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin Bioorganic & Medicinal Chemistry ·Koushi Hidaka, Tooru Kimura, Adam J. Ruben, Владимир Петрович Одинец, Shenghui Wu, Firqotun Naziah, Wael Qaisi, Adewale Oluwatosin Emmanuel, Yoshio Hayashi, Ernesto Freire, Yoshiaki Kiso	2008	24
7	‘O‐Acyl isopeptide method’ for peptide synthesis: Solvent effects in the synthesis of Aβ1–42 isopeptide using ‘O‐acyl isodipeptide unit’ Journal of Peptide Science ·Atsuhiko Taniguchi, Taku Yoshiya, Naoko Abe, Devia Febrina, Youhei Sohma, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso	2007	25
8	Development of O ‐acyl isopeptide method Biopolymers ·Youhei Sohma, Taku Yoshiya, Atsuhiko Taniguchi, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso	2007	71
9	Truncation and non-natural amino acid substitution studies on HTLV-I protease hexapeptidic inhibitors Bioorganic & Medicinal Chemistry Letters ·Jeffrey‐Tri Nguyen, Adi Zeevi, Kimberly Sancho, 高岸治人, Keiji Nishiyama, Tooru Kimura, Maosheng Cheng, Yoshio Hayashi, Yoshiaki Kiso	2007	18
10	Application of intramolecular carbonate-carbamate migration Queensland's institutional digital repository (The University of Queensland) ·Mariusz Skwarczyński, А. А. Гришкевич, Youhei Sohma, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso	2006	1
11	Structure of the aspartic protease plasmepsin 4 from the malarial parasitePlasmodium malariaebound to an allophenylnorstatine-based inhibitor Acta Crystallographica Section D Biological Crystallography ·José C. Clemente, L. Govindasamy, Amrita Madabushi, S. Zoë Fisher, Pierre Bordachar, Charles A. Yowell, Koushi Hidaka, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso, Mavis Agbandje‐McKenna, John B. Dame, Ben M. Dunn, R. McKenna	2006	40
12	Design and synthesis of potent β-secretase (BACE1) inhibitors with P1′ carboxylic acid bioisosteres Bioorganic & Medicinal Chemistry Letters ·Tooru Kimura, Y. Hamada, 義高興津, Rafael Enrique Olivero Verbe, N. O. Andersen, Hamdy M. Abdel‐Rahman, Rosa María Tedesco, Koushi Hidaka, Jeffrey‐Tri Nguyen, Kazuki Saito, Yoshio Hayashi, Yoshiaki Kiso	2006	52
13	Evaluation of Peptidomimetic Inhibitors against Malarial Protease Plasmepsin Adewale Oluwatosin Emmanuel, Koushi Hidaka, Ben Muok, Tooru Kimura, Yoshio Hayashi, Azin Nezami, Ernesto Freire, Yoshiaki Kiso	2005	1
14	The ‘O-acyl isopeptide method’ for the synthesis of difficult sequence-containing peptides: application to the synthesis of Alzheimer's disease-related amyloid β peptide (Aβ) 1-42 Journal of Peptide Science ·Youhei Sohma, Yoshio Hayashi, Maiko Kimura, M. О. Slabinoga, Atsuhiko Taniguchi, Masato Sasaki, Tooru Kimura, Yoshiaki Kiso	2005	81
15	Design and synthesis of highly active Alzheimer’s β-secretase (BACE1) inhibitors, KMI-420 and KMI-429, with enhanced chemical stability Bioorganic & Medicinal Chemistry Letters ·Tooru Kimura, ra Carmen Moreno-Vera, Y. Hamada, Rosa María Tedesco, Soko Kasai, Ping Liu, Koushi Hidaka, Takashi Hamada, Yoshio Hayashi, Yoshiaki Kiso	2004	70
16	Search for substrate‐based inhibitors fitting the S₂′ space of malarial aspartic protease plasmepsin II Journal of Peptide Science ·Firqotun Naziah, Koushi Hidaka, Tooru Kimura, Yoshio Hayashi, Azin Nezami, Ernesto Freire, Yoshiaki Kiso	2004	30
17	Substrate Transition-State Analogue Inhibitors of Plasmepsin II as Antimalarial Drugs Firqotun Naziah, Koushi Hidaka, Tooru Kimura, Yoshio Hayashi, Azin Nezami, Ernesto Freire, Yoshiaki Kiso	2003	1
18	Spontaneously Regenerable Prodrug : Design and Synthesis of Water-soluble Prodrugs of HIV Protease Inhibitors Hikaru Matsumoto, Youhei Sohma, ra Carmen Moreno-Vera, Marc A. Melser, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso	2001	1
19	KNI-577, a Potent Small-Sized HIV Protease Inhibitor Based on the Dipeptide Containing the Hydroxymethylcarbonyl Isostere as an Ideal Transition-State Mimic Archiv der Pharmazie ·Yoshiaki Kiso, Satoshi Yamaguchi, Hikaru Matsumoto, Tsutomu Mimoto, Ryohei Kato, Satoshi Nojima, Haruo Takaku, Tominaga Fukazawa, Tooru Kimura, Kenichi Akaji	1998	24
20	New hydroxyl protecting groups of a safety-catch type removable by reductive acidolysis. Chemical and Pharmaceutical Bulletin ·Yoshiaki Kiso, 肖绍球, Tooru Kimura, Cinu Modī, Kenichi Akaji	1991	9

About Tooru Kimura

Tooru Kimura is a scholar working on Virology, Organic Chemistry, Infectious Diseases, Computational Theory and Mathematics and Molecular Biology, having authored 109 papers that have together received 3.0k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (57 papers), HIV/AIDS drug development and treatment (30 papers), HIV Research and Treatment (19 papers), Click Chemistry and Applications (18 papers), Computational Drug Discovery Methods (16 papers), Carbohydrate Chemistry and Synthesis (13 papers), T-cell and Retrovirus Studies (10 papers) and Peptidase Inhibition and Analysis (9 papers). The work is most often cited by research in Organic Chemistry (1.2k citations), Virology (169 citations), Computational Theory and Mathematics (531 citations), Molecular Biology (1.8k citations) and Biomaterials (284 citations). Tooru Kimura has collaborated with scholars based in Japan, United States and China. Frequent co-authors include Yoshiaki Kiso, Yoshio Hayashi, Youhei Sohma, Koushi Hidaka, Y. Hamada, Masato Sasaki, Mariusz Skwarczyński, Atsuhiko Taniguchi, Kenichi Akaji and Hikaru Matsumoto. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Bioorganic & Medicinal Chemistry, Tetrahedron Letters, Journal of Peptide Science and Chemical and Pharmaceutical Bulletin.

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