Koushi Hidaka

2.3k citations

74 papers · 1.8k indexed · h-index 26

Computational Theory and Mathematics top 1%
- Computational Drug Discovery Methods 22
Virology top 10%
- HIV Research and Treatment 9
Aging top 10%
Molecular Biology top 10%
- Chemical Synthesis and Analysis 12
- Protein Structure and Dynamics 8
- RNA Interference and Gene Delivery 6
Organic Chemistry top 5%
- Click Chemistry and Applications 8
Infectious Diseases
- HIV/AIDS drug development and treatment 14
Public Health, Environmental and Occupational Health
- Malaria Research and Control 11

Co-authors: Yoshiaki Kiso Tooru Kimura Yoshio Hayashi Alan K. Soper Toshio Yamaguchi Ernesto Freire Y. Hamada Hiroshi Sugiyama
Cited by: Computational Theory and Mathematics Virology Aging
Journals: Proceedings of the National Academy of Sciences (2 papers)Nucleic Acids Research (1 paper)Angewandte Chemie International Edition (1 paper)
Partner nations: Japan United States Canada

In The Last Decade

Koushi Hidaka

73 papers receiving 1.8k citations

Peers

Countries citing papers authored by Koushi Hidaka

Since Specialization

Citations

This map shows the geographic impact of Koushi Hidaka's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Koushi Hidaka with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Koushi Hidaka more than expected).

Fields of papers citing papers by Koushi Hidaka

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Koushi Hidaka. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Koushi Hidaka. The network helps show where Koushi Hidaka may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Koushi Hidaka, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Koushi Hidaka Line = papers co-authored together Koushi Hidaka links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Controlling the stoichiometry and strand polarity of a tetramolecular G-quadruplex structure by using a DNA origami frame Nucleic Acids Research ·Arivazhagan Rajendran,Masayuki Endo,Koushi Hidaka,Phong Lan Thao Tran,Jean‐Louis Mergny,Hiroshi Sugiyama	2013	44
2	A Fluorogenic Probe for γ‐Glutamyl Cyclotransferase: Application of an Enzyme‐Triggered O‐to‐N Acyl Migration‐Type Reaction ChemBioChem ·Taku Yoshiya,Shugo Tsuda,Masayoshi Mochizuki,Koushi Hidaka,Yuko Tsuda,Yoshiaki Kiso,Susumu Kageyama,Hiromi Ii,Tatsuhiro Yoshiki,Yuji Nishiuchi	2013	10
3	Novel BACE1 inhibitors possessing a 5-nitroisophthalic scaffold at the P2 position Bioorganic & Medicinal Chemistry Letters ·Y. Hamada,Tomoya Nakanishi,Kenji Suzuki,Ryoji Yamaguchi,Takashi Hamada,Koushi Hidaka,Shoichi Ishiura,Yoshiaki Kiso	2012	15
4	Maintaining potent HTLV-I protease inhibition without the P3-cap moiety in small tetrapeptidic inhibitors Bioorganic & Medicinal Chemistry Letters ·Jeffrey‐Tri Nguyen,Keiko Kato,Henri‐Obadja Kumada,Koushi Hidaka,Tooru Kimura,Yoshiaki Kiso	2011	7
5	Structure-guided design and synthesis of P1′ position 1-phenylcycloalkylamine-derived pentapeptidic BACE1 inhibitors Bioorganic & Medicinal Chemistry ·Harichandra D. Tagad,Y. Hamada,Jeffrey‐Tri Nguyen,Koushi Hidaka,Takashi Hamada,Youhei Sohma,Tooru Kimura,Yoshiaki Kiso	2011	15
6	Improvement of both plasmepsin inhibitory activity and antimalarial activity by 2-aminoethylamino substitution Bioorganic & Medicinal Chemistry Letters ·Takuya Miura,Koushi Hidaka,Tsuyoshi Uemura,Keisuke Kashimoto,Yuto Hori,Yuko Kawasaki,Adam J. Ruben,Ernesto Freire,Tooru Kimura,Yoshiaki Kiso	2010	15
7	Design of pentapeptidic BACE1 inhibitors with carboxylic acid bioisosteres at P1′ and P4 positions Bioorganic & Medicinal Chemistry ·Harichandra D. Tagad,Y. Hamada,Jeffrey‐Tri Nguyen,Takashi Hamada,Hamdy M. Abdel‐Rahman,Abdellah Yamani,Ayaka Nagamine,Hayato Ikari,Naoto Igawa,Koushi Hidaka,Youhei Sohma,Tooru Kimura,Yoshiaki Kiso	2010	28
8	How Much Binding Affinity Can be Gained by Filling a Cavity? Chemical Biology & Drug Design ·Yuko Kawasaki,Eduardo E. Chufán,Virginie Lafont,Koushi Hidaka,Yoshiaki Kiso,L. Mario Amzel,Ernesto Freire	2009	41
9	Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin Bioorganic & Medicinal Chemistry ·Koushi Hidaka,Tooru Kimura,Adam J. Ruben,Tsuyoshi Uemura,Mami Kamiya,Aiko Kiso,Tetsuya Okamoto,Yumi Tsuchiya,Yoshio Hayashi,Ernesto Freire,Yoshiaki Kiso	2008	24
10	Crystallization and preliminary neutron diffraction studies of HIV-1 protease cocrystallized with inhibitor KNI-272 Acta Crystallographica Section F Structural Biology and Crystallization Communications ·Hiroyoshi Matsumura,Motoyasu Adachi,Shigeru Sugiyama,Shino Okada,M. Yamakami,Taro Tamada,Koushi Hidaka,Yoshio Hayashi,Tooru Kimura,Yoshiaki Kiso,Tomoya Kitatani,Sho Maki,Hiroshi Yoshikawa,Hiroaki Adachi,Kazufumi Takano,Satoshi Murakami,Tsuyoshi Inoue,Ryota Kuroki,Yusuke Mori	2008	14
11	Novel non-peptidic and small-sized BACE1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Y. Hamada,Hiroko Ohta,Naoko Miyamoto,Ryoji Yamaguchi,Abdellah Yamani,Koushi Hidaka,Tooru Kimura,Kazuki Saito,Yoshio Hayashi,Shoichi Ishiura,Yoshiaki Kiso	2008	35
12	Structure of the aspartic protease plasmepsin 4 from the malarial parasitePlasmodium malariaebound to an allophenylnorstatine-based inhibitor Acta Crystallographica Section D Biological Crystallography ·José C. Clemente,L. Govindasamy,Amrita Madabushi,S. Zoë Fisher,Rebecca E. Moose,Charles A. Yowell,Koushi Hidaka,Tooru Kimura,Yoshio Hayashi,Yoshiaki Kiso,Mavis Agbandje‐McKenna,John B. Dame,Ben M. Dunn,R. McKenna	2006	40
13	Design and synthesis of potent β-secretase (BACE1) inhibitors with P1′ carboxylic acid bioisosteres Bioorganic & Medicinal Chemistry Letters ·Tooru Kimura,Y. Hamada,Monika Stochaj,Hayato Ikari,Ayaka Nagamine,Hamdy M. Abdel‐Rahman,Naoto Igawa,Koushi Hidaka,Jeffrey‐Tri Nguyen,Kazuki Saito,Yoshio Hayashi,Yoshiaki Kiso	2006	52
14	Evaluation of Peptidomimetic Inhibitors against Malarial Protease Plasmepsin Yumi Tsuchiya,Koushi Hidaka,Akio Kiso,Tooru Kimura,Yoshio Hayashi,Azin Nezami,Ernesto Freire,Yoshiaki Kiso	2005	1
15	Design and synthesis of highly active Alzheimer’s β-secretase (BACE1) inhibitors, KMI-420 and KMI-429, with enhanced chemical stability Bioorganic & Medicinal Chemistry Letters ·Tooru Kimura,Daisuke Shuto,Y. Hamada,Naoto Igawa,Soko Kasai,Ping Liu,Koushi Hidaka,Takashi Hamada,Yoshio Hayashi,Yoshiaki Kiso	2004	70
16	Serine–arginine-rich nuclear protein Luc7l regulates myogenesis in mice Gene ·Erika Kimura,Koushi Hidaka,Yuji Kida,Hiroko Morisaki,Manabu Shirai,Kimi Araki,Misao Suzuki,Kazuhiko Yamamura,Takayuki Morisaki	2004	13
17	Search for substrate‐based inhibitors fitting the S₂′ space of malarial aspartic protease plasmepsin II Journal of Peptide Science ·Aiko Kiso,Koushi Hidaka,Tooru Kimura,Yoshio Hayashi,Azin Nezami,Ernesto Freire,Yoshiaki Kiso	2004	30
18	KMI-358 and KMI-370, highly potent and small-sized BACE1 inhibitors containing phenylnorstatine Bioorganic & Medicinal Chemistry Letters ·Tooru Kimura,Daisuke Shuto,Soko Kasai,Ping Liu,Koushi Hidaka,Takashi Hamada,Yoshio Hayashi,Chinatsu Hattori,Masashi Asai,Shinobu Kitazume,Takaomi C. Saido,Shoichi Ishiura,Yoshiaki Kiso	2004	52
19	Substrate Transition-State Analogue Inhibitors of Plasmepsin II as Antimalarial Drugs Aiko Kiso,Koushi Hidaka,Tooru Kimura,Yoshio Hayashi,Azin Nezami,Ernesto Freire,Yoshiaki Kiso	2003	1
20	Mouse Mef2b Gene: Unique Member of MEF2 Gene Family The Journal of Biochemistry ·Takayuki Morisaki,Kannika Sermsuvitayawong,Sang-Young Byun,Yoichi Matsuda,Koushi Hidaka,Hiroko Morisaki,T Mukai	1997	22

About Koushi Hidaka

Koushi Hidaka is a scholar working on Virology, Computational Theory and Mathematics and Infectious Diseases, having authored 74 papers that have together received 1.8k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (22 papers), HIV/AIDS drug development and treatment (14 papers), Chemical Synthesis and Analysis (12 papers), Malaria Research and Control (11 papers), HIV Research and Treatment (9 papers), Protein Structure and Dynamics (8 papers), Click Chemistry and Applications (8 papers) and RNA Interference and Gene Delivery (6 papers). The work is most often cited by research in Computational Theory and Mathematics (502 citations), Virology (73 citations) and Aging (24 citations). Koushi Hidaka has collaborated with scholars based in Japan, United States and Canada. Frequent co-authors include Yoshiaki Kiso, Tooru Kimura, Yoshio Hayashi, Alan K. Soper, Toshio Yamaguchi, Ernesto Freire, Y. Hamada, Hiroshi Sugiyama, Masayuki Endo and Jeffrey‐Tri Nguyen. Their work appears in journals such as Proceedings of the National Academy of Sciences, Nucleic Acids Research and Angewandte Chemie International Edition.

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