Radim Vrzal

2.7k total citations · 1 hit paper
80 papers, 2.2k citations indexed

About

Radim Vrzal is a scholar working on Pharmacology, Oncology and Molecular Biology. According to data from OpenAlex, Radim Vrzal has authored 80 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 44 papers in Pharmacology, 26 papers in Oncology and 22 papers in Molecular Biology. Recurrent topics in Radim Vrzal's work include Pharmacogenetics and Drug Metabolism (41 papers), Drug Transport and Resistance Mechanisms (21 papers) and Toxic Organic Pollutants Impact (19 papers). Radim Vrzal is often cited by papers focused on Pharmacogenetics and Drug Metabolism (41 papers), Drug Transport and Resistance Mechanisms (21 papers) and Toxic Organic Pollutants Impact (19 papers). Radim Vrzal collaborates with scholars based in Czechia, United States and France. Radim Vrzal's co-authors include Zdeněk Dvořák, Petr Pávek, Jitka Ulrichová, Lucie Stejskalová, Lucie Krausová, Michal Bitman, Patrick Maurel, Eva Anzenbacherová, Lucie Svecova and Sridhar Mani and has published in prestigious journals such as Nature Communications, PLoS ONE and Food Chemistry.

In The Last Decade

Radim Vrzal

79 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rifampicin Does not Significantly Affect the Expression of Small Heterodimer Partner in Primary Human Hepatocytes

2012 345 citations Petr Pávek, Lucie Krausová et al. profile →

Peers

Countries citing papers authored by Radim Vrzal

Since Specialization

Citations

This map shows the geographic impact of Radim Vrzal's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Radim Vrzal with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Radim Vrzal more than expected).

Fields of papers citing papers by Radim Vrzal

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Radim Vrzal. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Radim Vrzal. The network helps show where Radim Vrzal may publish in the future.

Co-authorship network of co-authors of Radim Vrzal

This figure shows the co-authorship network connecting the top 25 collaborators of Radim Vrzal. A scholar is included among the top collaborators of Radim Vrzal based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Radim Vrzal. Radim Vrzal is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Modulation of aryl hydrocarbon receptor activity by halogenated indoles 2024 ·Bioorganic & Medicinal Chemistry ·(unknown), Radim Vrzal, Petr Nádvorník, Marek Šebela, Zdeněk Dvořák	1
2	Orchestra of ligand-activated transcription factors in the molecular symphony of SERPINE 1 / PAI-1 gene regulation 2024 ·Biochimie ·(unknown), Radim Vrzal	2
3	Switching on/off aryl hydrocarbon receptor and pregnane X receptor activities by chemically modified tryptamines 2023 ·Toxicology Letters ·(unknown), (unknown), Radim Vrzal, (unknown), Miroslav Soural, (unknown), (unknown), Jan Vondráček, Zdeněk Dvořák	2
4	Monoterpenoid aryl hydrocarbon receptor allosteric antagonists protect against ultraviolet skin damage in female mice 2023 ·Nature Communications ·(unknown), (unknown), Barbora Vyhlídalová, Kristýna Krasulová, (unknown), Radim Vrzal, Petr Nádvorník, Binod Nepal, Sandhya Kortagere, Martina Kopečná, David Kopečný, Marek Šebela, Fraydoon Rastinejad, (unknown), Miroslav Soural, (unknown), Thomas Haarmann‐Stemmann, Hao Li, Sridhar Mani, Zdeněk Dvořák	28
5	Aryl Hydrocarbon Receptor (AhR)-Mediated Signaling in iPSC-Derived Human Motor Neurons 2022 ·Pharmaceuticals ·(unknown), Barbora Vagaská, Ján Kriška, Miroslava Anděrová, Mario Bortolozzi, Gino Gerosa, Patrizia Ferretti, Radim Vrzal	2
6	Antimigraine Drug Avitriptan Is a Ligand and Agonist of Human Aryl Hydrocarbon Receptor that Induces CYP1A1 in Hepatic and Intestinal Cells 2020 ·International Journal of Molecular Sciences ·Barbora Vyhlídalová, Kristýna Krasulová, (unknown), (unknown), Radim Vrzal, Zdeněk Andrysík, Aneesh Chandran, Sridhar Mani, Zdeněk Dvořák	8
7	The effect of graphene oxide on signalling of xenobiotic receptors involved in biotransformation 2020 ·Chemosphere ·(unknown), (unknown), Petr Bachleda, (unknown), Aleš Panáček, Libor Kvı́tek, Radim Vrzal	7
8	Mycophenolate Mofetil induces c-Jun-N-terminal kinase expression in 22Rv1 cells: an impact on androgen receptor signaling 2018 ·Journal of Cancer ·(unknown), Zdeněk Dvořák, Radim Vrzal	2
9	In vitro modulatory effects of functionalized pyrimidines and piperidine derivatives on Aryl hydrocarbon receptor (AhR) and glucocorticoid receptor (GR) activities 2017 ·Bioorganic Chemistry ·Muhammad Yar, Lubna Shahzadi, (unknown), (unknown), José P. Cerón‐Carrasco, Helena den-Haan, Sanjay Kumar, Jorge Peña‐García, Horacio Pérez‐Sánchez, (unknown), Zdeněk Dvořák, Radim Vrzal	2
10	The effects of drugs with immunosuppressive or immunomodulatory activities on xenobiotics-metabolizing enzymes expression in primary human hepatocytes 2015 ·Toxicology in Vitro ·Radim Vrzal, (unknown), Petr Bachleda, Zdeněk Dvořák	12
11	Dehydroepiandrosterone post-transcriptionally modifies CYP1A2 induction involving androgen receptor 2013 ·Chemico-Biological Interactions ·(unknown), Katalin Tóth, Radim Vrzal, (unknown), (unknown), Erika Orbán, Damjana Rozman, Zdeněk Dvořák, Katalin Monostory	2
12	Khellin and Visnagin Differentially Modulate AHR Signaling and Downstream CYP1A Activity in Human Liver Cells 2013 ·PLoS ONE ·Radim Vrzal, (unknown), Peter Proksch, Josef Abel, Zdeněk Dvořák, Thomas Haarmann‐Stemmann	30
13	Construction and characterization of hepatocyte nuclear factor HNF4alpha1 over-expressing cell line derived from human hepatoma HepG2 cells 2011 ·European Journal of Pharmacology ·(unknown), (unknown), Radim Vrzal, Petr Pávek, Zdeněk Dvořák	4
14	Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug‐metabolizing cytochrome P450 enzymes 2010 ·Journal of Thrombosis and Haemostasis ·(unknown), (unknown), Lucie Krausová, Michal Bitman, Radim Vrzal, Zdeněk Dvořák, J Blahoš, Petr Pávek	46
15	Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: Investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines 2010 ·Toxicology Letters ·Radim Vrzal, (unknown), Petr Pávek, Zdeněk Dvořák	21
16	Evaluation of in vitro cytotoxicity and hepatotoxicity of platinum(II) and palladium(II) oxalato complexes with adenine derivatives as carrier ligands 2010 ·Journal of Inorganic Biochemistry ·Radim Vrzal, Pavel Štarha, Zdeněk Dvořák, Zdeněk Trávnı́ček	41
17	Investigation of the CYP2C9 Induction Profile in Human Hepatocytes by Combining Experimental and Modelling Approaches 2009 ·Current Drug Metabolism ·(unknown), (unknown), (unknown), Radim Vrzal, Zdeněk Dvořák, Damjana Rozman, Katalin Monostory	7
18	Azole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene Expression 2007 ·Drug Metabolism and Disposition ·Lucie Svecova, Radim Vrzal, Ladislav Burýšek, Eva Anzenbacherová, Lukáš Červený, (unknown), František Trejtnar, Jiřı́ Kuneš, Milan Pour, František Štaud, Pavel Anzenbacher, Zdeněk Dvořák, Petr Pávek	50
19	Involvement of Cytoskeleton in AhR-Dependent CYP1A1 Expression 2006 ·Current Drug Metabolism ·Zdeněk Dvořák, Radim Vrzal, Jitka Ulrichová, Jean‐Marc Pascussi, Patrick Maurel, Martin Modrianský	16
20	Differential effects of selected natural compounds with anti-inflammatory activity on the glucocorticoid receptor and NF-κB in HeLa cells 2005 ·Chemico-Biological Interactions ·Zdeněk Dvořák, Radim Vrzal, Patrick Maurel, Jitka Ulrichová	59

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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