Timothy S. Heuer

1.8k citations

19 papers · 1.4k indexed · 1 hit paper · h-index 11

Co-authors: Patrick O. Brown George Kemble Douglas Buckley Marcia Belvin Laurent Troxler Marina Fridlib Richard Ventura Casey Kopczynski
Topics: Cancer, Lipids, and Metabolism (11 papers)Cancer, Hypoxia, and Metabolism (10 papers)Peroxisome Proliferator-Activated Receptors (6 papers)
Cited by: Virology Cancer Research Insect Science
Journals: Proceedings of the National Academy of Sciences Biochemistry Cancer Research
Partner nations: United States France Germany

In The Last Decade

Timothy S. Heuer

19 papers receiving 1.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A genome-wide analysis of immune responses in Drosophila

2001 328 citations Laurent Troxler, Timothy S. Heuer et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by Timothy S. Heuer

Since Specialization

Citations

This map shows the geographic impact of Timothy S. Heuer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Timothy S. Heuer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Timothy S. Heuer more than expected).

Fields of papers citing papers by Timothy S. Heuer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Timothy S. Heuer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Timothy S. Heuer. The network helps show where Timothy S. Heuer may publish in the future.

Co-authorship network of co-authors of Timothy S. Heuer

This figure shows the co-authorship network connecting the top 25 collaborators of Timothy S. Heuer. A scholar is included among the top collaborators of Timothy S. Heuer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Timothy S. Heuer. Timothy S. Heuer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

#	Work	Indexed citations
1	Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer 2018 ·Oncotarget ·Yekaterina Y. Zaytseva,Piotr Rychahou,(unknown),Timothy Scott,Robert M Flight,Ji Tae Kim,Jennifer W. Harris,Jinpeng Liu,Chi Wang,Andrew J. Morris,Theru A. Sivakumaran,Teresa W.‐M. Fan,Hunter Moseley,Tianyan Gao,Eun Y. Lee,Heidi L. Weiss,Timothy S. Heuer,George Kemble,Mark B. Evers	97
2	Fatty acid synthase – Modern tumor cell biology insights into a classical oncology target 2017 ·Pharmacology & Therapeutics ·Douglas Buckley,Gregory Duke,Timothy S. Heuer,Marie O’Farrell,Allan S. Wagman,William McCulloch,George Kemble	151
3	FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Expression 2016 ·EBioMedicine ·Timothy S. Heuer,Richard Ventura,Kasia Mordec,Julie Lai,Marina Fridlib,Douglas Buckley,George Kemble	103
4	Abstract 1010: Evaluation of small-molecule FASN inhibitors in preclinical models of colorectal cancer 2016 ·Cancer Research ·Yekaterina Y. Zaytseva,Piotr Rychahou,Tianyan Gao,Eun Y. Lee,Heidi L. Weiss,Timothy S. Heuer,George Kemble,B. Mark Evers	2
5	Abstract 4743: Preclinical studies characterize tumor type sensitivity to FASN inhibition and the mechanism and efficacy of novel drug combinations with TVB-2640 2016 ·Cancer Research ·Timothy S. Heuer,Richard Ventura,Julie Lai,Joanna Waszczuk,Claudia Grau Rubio,R. Glenn Hammonds,(unknown),Douglas Buckley,George Kemble	1
6	De Novo Palmitate Synthesis Supports Oncogenic Signalling and Tumor Growth Through Diverse Mechanisms: Implications for FASN-Targeted Therapeutics 2016 ·Timothy S. Heuer	3
7	Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression 2015 ·EBioMedicine ·Richard Ventura,Kasia Mordec,Joanna Waszczuk,Zhaoti Wang,Julie Lai,Marina Fridlib,Douglas Buckley,George Kemble,Timothy S. Heuer	234
8	Abstract 2675: Biomarker and PK/PD analyses of first in class FASN inhibitor TVB-2640 in a first-in-human phase 1 study in solid tumor patients 2015 ·Cancer Research ·Marie O’Farrell,R. Webster Crowley,Timothy S. Heuer,(unknown),Chris Rubino,William McCulloch,George Kemble	2
9	Abstract B13: Biomarker Analyses from Dose Escalation Phase of FASN Inhibitor TVB-2640 Phase 1 Study Shows Target Engagement in Solid Tumor Patients 2015 ·Molecular Cancer Therapeutics ·Marie O’Farrell,R. Webster Crowley,Timothy S. Heuer,Marina Fridlib,(unknown),William McCulloch,George Kemble	1
10	Diacylglycerol Metabolism and Signaling Is a Driving Force Underlying FASN Inhibitor Sensitivity in Cancer Cells 2015 ·ACS Chemical Biology ·Daniel I. Benjamin,(unknown),(unknown),Timothy S. Heuer,George Kemble,Daniel K. Nomura	51
11	Abstract 4446: Discovery of tumor types highly susceptible to FASN inhibition and biomarker candidates for clinical analysis 2015 ·Cancer Research ·Timothy S. Heuer,Richard Ventura,Kasia Mordec,Julie Lai,Joanna Waszczuk,R. Glenn Hammonds,Marina Fridlib,Russell J. Johnson,Lily Hu,Allan S. Wagman,Marie O’Farrell,Douglas Buckley,George Kemble	2
12	EXEL-7647 Inhibits Mutant Forms of ErbB2 Associated with Lapatinib Resistance and Neoplastic Transformation 2008 ·Clinical Cancer Research ·Torsten Trowe,Sotiria Boukouvala,(unknown),Richard E. Cutler,(unknown),Roel Funke,Steven Gendreau,(unknown),Nicole Miller,John Woolfrey,Valentina Vysotskaia,(unknown),Mary E. Gerritsen,David J. Matthews,Peter Lamb,Timothy S. Heuer	94
13	291 POSTER Discovery of selective CDK9 small molecule inhibitors: CDK9 inhibition in tumor cells is associated with inhibition of proliferation and induction of apoptosis 2008 ·European Journal of Cancer Supplements ·Timothy S. Heuer	2
14	Continuous Complete Hematological and Cytogenetic Remission with Molecular Minimal Residual Disease 9 Years after Discontinuation of Interferon-α in a Patient with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia 2006 ·Acta Haematologica ·Walter Verbeek,Helmut König,Juergen Boehm,(unknown),Claudia Lange,Timothy S. Heuer,Carmen Scheibenbogen,H. E. Reis,Andreas Hochhaus,Ullrich Graeven	9
15	A genome-wide analysis of immune responses in Drosophilabreakdown → 2001 ·Proceedings of the National Academy of Sciences ·(unknown),Laurent Troxler,Timothy S. Heuer,Marcia Belvin,Casey Kopczynski,Jean‐Marc Reichhart,Jules A. Hoffmann,Charles Hétru	328
16	Photo-Cross-Linking Studies Suggest a Model for the Architecture of an Active Human Immunodeficiency Virus Type 1 Integrase−DNA Complex 1998 ·Biochemistry ·Timothy S. Heuer,Patrick O. Brown	133
17	Mapping Features of HIV-1 Integrase Near Selected Sites on Viral and Target DNA Molecules in an Active Enzyme−DNA Complex by Photo-Cross-Linking 1997 ·Biochemistry ·Timothy S. Heuer,Patrick O. Brown	116
18	Characterization of recombinant murine leukemia virus integrase 1995 ·Journal of Virology ·Iris Dotan,Brian Scottoline,Timothy S. Heuer,Patrick O. Brown	33
19	Folding of group I introns from bacteriophage T4 involves internalization of the catalytic core. 1991 ·Proceedings of the National Academy of Sciences ·Timothy S. Heuer,P. Scott Chandry,Marlene Belfort,Daniel W. Celander,Thomas R. Cech	34

About Timothy S. Heuer

Timothy S. Heuer is a scholar working on Cancer Research, Virology and Molecular Biology, having authored 19 papers that have together received 1.4k indexed citations. Recurring topics across this work include Cancer, Lipids, and Metabolism (11 papers), Cancer, Hypoxia, and Metabolism (10 papers) and Peroxisome Proliferator-Activated Receptors (6 papers). The work is most often cited by research in Virology (238 citations), Cancer Research (544 citations) and Insect Science (218 citations). Timothy S. Heuer has collaborated with scholars based in United States, France and Germany. Frequent co-authors include Patrick O. Brown, George Kemble, Douglas Buckley, Marcia Belvin, Laurent Troxler, Marina Fridlib, Richard Ventura, Casey Kopczynski, Jules A. Hoffmann and Charles Hétru. Their work appears in journals such as Proceedings of the National Academy of Sciences, Biochemistry and Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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