Timothy R. Hercus

2.4k citations

39 papers · 1.8k indexed · h-index 24

Impact in

Immunology top 2%
- Immune Cell Function and Interaction
- Immune Response and Inflammation
- Immunotherapy and Immune Responses
- T-cell and B-cell Immunology
- Immune cells in cancer
Immunology and Allergy top 5%

Papers in

Immunology 30
- Immune Response and Inflammation 15
- Immune Cell Function and Interaction 14
- T-cell and B-cell Immunology 8
- Immunotherapy and Immune Responses 8
Immunology and Allergy 4
- Cell Adhesion Molecules Research 4

Co-authors: Angel F. López Michael W. Parker Joanna M. Woodcock Sophie E. Broughton Mark A. Guthridge Mara Dottore Paul G. Ekert Tracy L. Nero
Journals: Blood (6 papers)Journal of Allergy and Clinical Immunology (3 papers)Cytokine & Growth Factor Reviews (2 papers)Immunological Reviews (2 papers)The EMBO Journal (2 papers)
Partner nations: Australia United States Canada

In The Last Decade

Timothy R. Hercus

38 papers receiving 1.8k citations

Peers

Countries citing papers authored by Timothy R. Hercus

Since Specialization

Citations

This map shows the geographic impact of Timothy R. Hercus's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Timothy R. Hercus with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Timothy R. Hercus more than expected).

Fields of papers citing papers by Timothy R. Hercus

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Timothy R. Hercus. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Timothy R. Hercus. The network helps show where Timothy R. Hercus may publish in the future.

Co-authors

The 25 scholars most cited alongside Timothy R. Hercus, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Timothy R. Hercus Line = papers co-authored together Timothy R. Hercus links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The β Common Cytokine Receptor Family Reveals New Functional Paradigms From Structural Complexities Immunological Reviews ·Winnie L. Kan, Claire M. Weekley, Tracy L. Nero, Timothy R. Hercus, Kwok Ho Yip, Damon J. Tumes, Joanna M. Woodcock, David M. Ross, Danièl Thomas, D. Teran, Catherine M. Owczarek, Ning Liu, Luciano G. Martelotto, José M. Polo, Harshita Pant, Denis Tvorogov, Angel F. López, Michael W. Parker	2025	1
2	CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting PLoS ONE ·Kelly Lim, Winnie L. Kan, Pramod C. Nair, Monika Kutyna, Angel F. López, Timothy R. Hercus, David M. Ross, Steven Lane, Chun Yew Fong, Anna Brown, Agnes S. M. Yong, David T Yeung, Timothy P. Hughes, Devendra Hiwase, Danièl Thomas	2024	0
3	Dual inhibition of airway inflammation and fibrosis by common β cytokine receptor blockade Journal of Allergy and Clinical Immunology ·Hao Wang, Kwok Ho Yip, Simon P. Keam, Ross Vlahos, Kristy Nichol, Peter Wark, John Toubia, Anita Kral, Gökhan Cildir, Harshita Pant, Timothy R. Hercus, Nick Wilson, Catherine M. Owczarek, Angel F. López, Steven Bozinovski, Damon J. Tumes	2023	7
4	Translating the biology of β common receptor-engaging cytokines into clinical medicine Journal of Allergy and Clinical Immunology ·Harshita Pant, Timothy R. Hercus, Damon J. Tumes, Kwok Ho Yip, Michael W. Parker, Catherine M. Owczarek, Angel F. López, David P. Huston	2022	10
5	Blocking the human common beta subunit of the GM-CSF, IL-5 and IL-3 receptors markedly reduces hyperinflammation in ARDS models Cell Death and Disease ·Hao Wang, Damon J. Tumes, Timothy R. Hercus, Kwok Ho Yip, Christian Aloe, Ross Vlahos, Angel F. López, Nick Wilson, Catherine M. Owczarek, Steven Bozinovski	2022	23
6	Messing with βc: A unique receptor with many goals Seminars in Immunology ·Winnie L. Kan, Karen S. Cheung Tung Shing, Tracy L. Nero, Timothy R. Hercus, Denis Tvorogov, Michael W. Parker, Angel F. López	2021	3
7	Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis Science Advances ·Denis Tvorogov, Danièl Thomas, Nicholas P. D. Liau, Mara Dottore, Emma F. Barry, Maya Lathi, Winnie L. Kan, Timothy R. Hercus, Frank C. Stomski, Timothy P. Hughes, Vinay Tergaonkar, Michael W. Parker, David M. Ross, Ravindra Majeti, Jeffrey J. Babon, Angel F. López	2018	41
8	A dual role for the N-terminal domain of the IL-3 receptor in cell signalling Nature Communications ·Sophie E. Broughton, Timothy R. Hercus, Tracy L. Nero, Winnie L. Kan, Emma F. Barry, Mara Dottore, Karen S. Cheung Tung Shing, Craig J. Morton, Urmi Dhagat, Matthew P. Hardy, Nicholas J. Wilson, Matthew T. Downton, Christine Schieber, Timothy P. Hughes, Angel F. López, Michael W. Parker	2018	31
9	Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling Structure ·Sophie E. Broughton, Timothy R. Hercus, Tracy L. Nero, Mara Dottore, Barbara J. McClure, Urmi Dhagat, Houng Taing, Michael A. Gorman, J. King-Scott, Angel F. López, Michael W. Parker	2016	40
10	The βc receptor family – Structural insights and their functional implications Cytokine ·Sophie E. Broughton, Tracy L. Nero, Urmi Dhagat, Winnie L. Kan, Timothy R. Hercus, Denis Tvorogov, Angel F. López, Michael W. Parker	2015	60
11	Signalling by the beta c family of cytokines Cytokine & Growth Factor Reviews ·Timothy R. Hercus, Urmi Dhagat, Winnie L. Kan, Sophie E. Broughton, Tracy L. Nero, Michelle Perugini, Jarrod J. Sandow, Richard J. D’Andrea, Paul G. Ekert, Timothy R. Hughes, Michael W. Parker, Angel F. López	2013	2
12	High Yield Production of a Soluble Human Interleukin-3 Variant from E. coli with Wild-Type Bioactivity and Improved Radiolabeling Properties PLoS ONE ·Timothy R. Hercus, Emma F. Barry, Mara Dottore, Barbara J. McClure, Andrew I. Webb, Angel F. López, Ian G. Young, James M. Murphy	2013	12
13	The GM-CSF receptor family: Mechanism of activation and implications for disease Growth Factors ·Timothy R. Hercus, Sophie E. Broughton, Paul G. Ekert, Hayley S. Ramshaw, Michelle Perugini, Michele A. Grimbaldeston, Joanna M. Woodcock, Danièl Thomas, Stuart M. Pitson, Timothy P. Hughes, Richard J. D’Andrea, Michael W. Parker, Angel F. López	2012	56
14	Molecular basis of cytokine receptor activation IUBMB Life ·Angel F. López, Timothy R. Hercus, Paul G. Ekert, Dene R. Littler, Mark A. Guthridge, Danièl Thomas, Hayley S. Ramshaw, Frank C. Stomski, Michelle Perugini, Richard J. D’Andrea, Michele A. Grimbaldeston, Michael W. Parker	2010	54
15	The Structure of the GM-CSF Receptor Complex Reveals a Distinct Mode of Cytokine Receptor Activation Cell ·Guido Hansen, Timothy R. Hercus, Barbara J. McClure, Frank C. Stomski, Mara Dottore, Jason A. Powell, Hayley S. Ramshaw, Joanna M. Woodcock, Yibin Xu, Mark A. Guthridge, William J. McKinstry, Angel F. López, Michael W. Parker	2008	229
16	Crystallization and preliminary X-ray diffraction analysis of the ternary human GM-CSF receptor complex Acta Crystallographica Section F Structural Biology and Crystallization Communications ·Guido Hansen, Timothy R. Hercus, Yibin Xu, Angel F. López, Michael W. Parker, William J. McKinstry	2008	6
17	Sphingosine Activates Protein Kinase A Type II by a Novel cAMP-independent Mechanism Journal of Biological Chemistry ·Yuefang Ma, Stuart M. Pitson, Timothy R. Hercus, Jane Murphy, Angel F. López, Joanna M. Woodcock	2005	58
18	The Apoptosis-inducing Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Analog E21R Functions through Specific Regions of the Heterodimeric GM-CSF Receptor and Requires Interleukin-1β-converting Enzyme-like Proteases Journal of Biological Chemistry ·Per Ole Iversen, Timothy R. Hercus, B. Zacharakis, Joanna M. Woodcock, Frank C. Stomski, Sharad Kumar, Brad H. Nelson, Atsushi Miyajima, Angel F. López	1997	12
19	Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF. The EMBO Journal ·Joanna M. Woodcock, B. Zacharakis, Geert Plaetinck, C.J. Bagley, Smith Jim Q., Timothy R. Hercus, Jan Tavernier, Angel F. López	1994	103
20	Cytokines and allergy Journal of Allergy and Clinical Immunology ·Mathew A. Vadas, Angel F. López, Jennifer R. Gamble, Yeesim Khew‐Goodall, William Smith, Christophe Bernard, Gillian Cockerill, Peter N. Cockerill, Frances Shannon, Qiyu Sun, Eija Korpelainen, Cameron J. van den Heuvel, Timothy R. Hercus	1994	15

About Timothy R. Hercus

Timothy R. Hercus is a scholar working on Immunology, Immunology and Allergy, Microbiology, Oncology and Hematology, having authored 39 papers that have together received 1.8k indexed citations. Recurring topics across this work include Immune Response and Inflammation (15 papers), Immune Cell Function and Interaction (14 papers), Cytokine Signaling Pathways and Interactions (10 papers), T-cell and B-cell Immunology (8 papers), Immunotherapy and Immune Responses (8 papers), Monoclonal and Polyclonal Antibodies Research (6 papers), Asthma and respiratory diseases (5 papers) and Cell Adhesion Molecules Research (4 papers). The work is most often cited by research in Immunology (1.1k citations), Immunology and Allergy (118 citations), Hematology (205 citations), Oncology (458 citations) and Genetics (103 citations). Timothy R. Hercus has collaborated with scholars based in Australia, United States and Canada. Frequent co-authors include Angel F. López, Michael W. Parker, Joanna M. Woodcock, Sophie E. Broughton, Mark A. Guthridge, Mara Dottore, Paul G. Ekert, Tracy L. Nero, Danièl Thomas and Urmi Dhagat. Their work appears in journals such as Blood, Journal of Allergy and Clinical Immunology, Cytokine & Growth Factor Reviews, Immunological Reviews and The EMBO Journal.

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