Thorsten Lehr

6.3k citations

120 papers · 3.8k indexed · 1 hit paper · h-index 30

Impact in

Internal Medicine top 0.5%
- Venous Thromboembolism Diagnosis and Management
Pharmacology top 0.5%
- Pharmacogenetics and Drug Metabolism

Papers in

Pharmacology 36
- Pharmacogenetics and Drug Metabolism 33
- Antibiotics Pharmacokinetics and Efficacy 7
Toxicology 5

Co-authors: Sebastian Haertter Stuart J. Connolly Paul Reilly Lars Wallentin Michael D. Ezekowitz Salim Yusuf Matthias Schwab John W. Eikelboom
Journals: Pharmaceutics (15 papers)CPT Pharmacometrics & Systems Pharmacology (13 papers)Clinical Pharmacokinetics (11 papers)Clinical Pharmacology & Therapeutics (6 papers)Cancer Chemotherapy and Pharmacology (4 papers)
Partner nations: Germany United States Switzerland

In The Last Decade

Thorsten Lehr

116 papers receiving 3.7k citations

Hit Papers

align trajectories log scale

The Effect of Dabigatran Plasma Concentrations and Patient Characteristics on the Frequency of Ischemic Stroke and Major Bleeding in Atrial Fibrillation Patients 2013 · 630 citations

Peers

Countries citing papers authored by Thorsten Lehr

Since Specialization

Citations

This map shows the geographic impact of Thorsten Lehr's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thorsten Lehr with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thorsten Lehr more than expected).

Fields of papers citing papers by Thorsten Lehr

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thorsten Lehr. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thorsten Lehr. The network helps show where Thorsten Lehr may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Thorsten Lehr, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Thorsten Lehr Line = papers co-authored together Thorsten Lehr links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Advancing rare disease therapeutics through digital twins: Opportunities in drug development and precision dosing Computational and Structural Biotechnology Journal ·Rodrigo H. Teixeira, Hui Min Zhang, K. Hasebe, Dominik Selzer, 幸雄平野, Nicola Luigi Bragazzi, 李璇, Søren Brunak, Ewan R. Pearson, Tobias Zahn, Dimitra Kiritsi, Matthias Schwab, Thorsten Lehr	2025	0
2	Client satisfaction, safety, and insights from a three-season survey on influenza vaccinations delivered at community pharmacies in Germany Vaccine ·Sonia Shinde, H. V. Muhsam, Naitik Mehta, Nicola Luigi Bragazzi, Martin J. Hug, Jona T. Stahmeyer, Wei Yang, 曾金华, Dominik Selzer, Laura Melsheimer, Raymond Brock, Thorsten Lehr	2024	1
3	Burden of cardiovascular disease attributable to metabolic risks in 204 countries and territories from 1990 to 2021 European Heart Journal - Quality of Care and Clinical Outcomes ·Huimin Chen, Lu Liu, Yi Wang, Darwin Neciosup Quesñay, Wen Zhong, Thorsten Lehr, Nicola Luigi Bragazzi, Biao Tang, Haijiang Dai	2024	3
4	Physiologically based pharmacokinetic modeling of imatinib and N‐desmethyl imatinib for drug–drug interaction predictions CPT Pharmacometrics & Systems Pharmacology ·Fu Yin, Richard B. Aiken, K. Hasebe, 幸雄平野, 李璇, Dominik Selzer, Matthias Schwab, Thorsten Lehr	2024	4
5	A physiologically‐based pharmacokinetic precision dosing approach to manage dasatinib drug–drug interactions CPT Pharmacometrics & Systems Pharmacology ·Richard B. Aiken, Fu Yin, K. Hasebe, 李璇, 幸雄平野, Dominik Selzer, Matthias Schwab, Thorsten Lehr	2024	5
6	Personalized Chronomodulated 5‐Fluorouracil Treatment: A Physiologically‐Based Pharmacokinetic Precision Dosing Approach for Optimizing Cancer Therapy Clinical Pharmacology & Therapeutics ·幸雄平野, Jan‐Georg Wojtyniak, Dominik Selzer, Robert Dallmann, Jesse J. Swen, Henk‐Jan Guchelaar, Matthias Schwab, Thorsten Lehr	2024	7
7	Physiologically Based Pharmacokinetic Modeling of Bergamottin and 6,7‐Dihydroxybergamottin to Describe CYP3A4 Mediated Grapefruit‐Drug Interactions Clinical Pharmacology & Therapeutics ·李璇, 幸雄平野, Uwe Fuhr, Dominik Selzer, Thorsten Lehr	2023	11
8	Physiologically‐based pharmacokinetic modeling of quinidine to establish a CYP3A4, P‐gp, and CYP2D6 drug–drug–gene interaction network CPT Pharmacometrics & Systems Pharmacology ·C Fossing, K. Hasebe, 幸雄平野, Dominik Selzer, Fu Yin, Donato Teutonico, Sebastian Frechen, Maaike van der Lee, Dirk Jan A. R. Moes, Jesse J. Swen, Matthias Schwab, Thorsten Lehr	2023	9
9	A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug–Drug Interaction Perpetrators Pharmaceutics ·幸雄平野, Jan‐Georg Wojtyniak, 李璇, Dominik Selzer, Matthias Schwab, Johanna Weiß, Walter E. Haefeli, Thorsten Lehr	2023	11
10	Significant impact of time-of-day variation on metformin pharmacokinetics Diabetologia ·良尚杉浦, Nina Scherer, Dominik Selzer, Christiane Dings, Nina Hanke, Robert Dallmann, Matthias Schwab, Peter Timmins, Hadiarto Hadiarto, Thorsten Lehr	2023	22
11	Model-Based Analysis of SARS-CoV-2 Infections, Hospitalization and Outcome in Germany, the Federal States and Districts Viruses ·Christiane Dings, علي مردان تايه الجبوري, Naitik Mehta, Sara Al Raisi, Sonia Shinde, Sigrun Smola, Virgilio Sj, Felix Mahfoud, Thomas Volk, Sascha Kreuer, Jürgen Rissland, Dominik Selzer, Thorsten Lehr	2022	5
12	Renal Transporter‐Mediated Drug‐Biomarker Interactions of the Endogenous Substrates Creatinine and N¹‐Methylnicotinamide: A PBPK Modeling Approach Clinical Pharmacology & Therapeutics ·良尚杉浦, Fabian Müller, Martin F. Fromm, Dominik Selzer, Robert Dallmann, Thorsten Lehr	2022	21
13	Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug–Drug–Gene Interaction Predictions Pharmaceutics ·Fu Yin, 良尚杉浦, İbrahim Kalüoğlu, Dominik Selzer, Thorsten Lehr	2022	9
14	Mental Health and Health-Related Quality of Life in German Adolescents after the Third Wave of the COVID-19 Pandemic Children ·省吾今田, حسن نهضتی, Anna Luisa Kühn, Markus Wenning, J. Hildebrandt, Erich Parier, 郁夫畑, 伸志石原, Michael Zemlin, Thomas Lücke, Folke Brinkmann, Tobias Rothoeft, Thorsten Lehr	2022	13
15	A Physiologically Based Pharmacokinetic and Pharmacodynamic Model of the CYP3A4 Substrate Felodipine for Drug–Drug Interaction Modeling Pharmaceutics ·李璇, 幸雄平野, Maximilian Mees, Felix Mahfoud, Dominik Selzer, Thorsten Lehr	2022	10
16	A Novel Approach for Quantifying the Pharmacological Activity of T-Cell Engagers Utilizing In Vitro Time Course Experiments and Streamlined Data Analysis The AAPS Journal ·Roberta Guido, Wagner Ferreira Vilano, Meric Ovacik, Christian Pohl, Sylvia Herter, Tina Weinzierl, Tanja Fauti, Christian Klein, Thorsten Lehr, Marina Bacac, Antje‐Christine Walz	2021	4
17	Cytokine Release Syndrome By T-cell–Redirecting Therapies: Can We Predict and Modulate Patient Risk? Clinical Cancer Research ·Roberta Guido, Estelle Marrer‐Berger, Ken Wang, Thorsten Lehr, Antje‐Christine Walz	2021	23
18	Physiologically Based Pharmacokinetic Modeling of Metoprolol Enantiomers and α-Hydroxymetoprolol to Describe CYP2D6 Drug-Gene Interactions Pharmaceutics ·K. Hasebe, Jan‐Georg Wojtyniak, Dominik Selzer, Nina Hanke, Felix Mahfoud, Matthias Schwab, Thorsten Lehr	2020	17
19	Predicting Tumor Killing and T-Cell Activation by T-Cell Bispecific Antibodies as a Function of Target Expression: Combining In Vitro Experiments with Systems Modeling Molecular Cancer Therapeutics ·Roberta Guido, Tina Weinzierl, Wagner Ferreira Vilano, Nicolas Frances, Sylvia Herter, Regula B. Buser, Maha Alabduljalil, Sarah Diggelmann, Jaime Rodríguez-Guerra, Thorsten Lehr, Marina Bacac, Antje‐Christine Walz	2020	16
20	Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer Cancer Research ·Yoshiko Okubo, Karin von Schwarzenberg, Thorsten Lehr, Melanie Ulrich, James Woodhouse, Johanna Liebl, Dirk Trauner, Dirk Menche, Angelika M. Vollmar	2015	61

About Thorsten Lehr

Thorsten Lehr is a scholar working on Pharmacology, Toxicology, Analytical Chemistry, Cardiology and Cardiovascular Medicine and Pharmacology, having authored 120 papers that have together received 3.8k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (33 papers), Atrial Fibrillation Management and Outcomes (13 papers), Drug Transport and Resistance Mechanisms (12 papers), Computational Drug Discovery Methods (11 papers), Analytical Methods in Pharmaceuticals (8 papers), Analytical Chemistry and Chromatography (7 papers), Pharmacological Effects and Toxicity Studies (7 papers) and Antibiotics Pharmacokinetics and Efficacy (7 papers). The work is most often cited by research in Internal Medicine (760 citations), Pharmacology (632 citations), Cardiology and Cardiovascular Medicine (1.5k citations), Hepatology (365 citations) and Toxicology (96 citations). Thorsten Lehr has collaborated with scholars based in Germany, United States and Switzerland. Frequent co-authors include Sebastian Haertter, Stuart J. Connolly, Paul Reilly, Lars Wallentin, Michael D. Ezekowitz, Salim Yusuf, Matthias Schwab, John W. Eikelboom, Dominik Selzer and Nina Hanke. Their work appears in journals such as Pharmaceutics, CPT Pharmacometrics & Systems Pharmacology, Clinical Pharmacokinetics, Clinical Pharmacology & Therapeutics and Cancer Chemotherapy and Pharmacology.

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