Christian Klein

27.5k total citations · 4 hit papers
345 papers, 15.6k citations indexed

About

Christian Klein is a scholar working on Oncology, Radiology, Nuclear Medicine and Imaging and Molecular Biology. According to data from OpenAlex, Christian Klein has authored 345 papers receiving a total of 15.6k indexed citations (citations by other indexed papers that have themselves been cited), including 162 papers in Oncology, 130 papers in Radiology, Nuclear Medicine and Imaging and 106 papers in Molecular Biology. Recurrent topics in Christian Klein's work include Monoclonal and Polyclonal Antibodies Research (121 papers), CAR-T cell therapy research (90 papers) and Chronic Lymphocytic Leukemia Research (60 papers). Christian Klein is often cited by papers focused on Monoclonal and Polyclonal Antibodies Research (121 papers), CAR-T cell therapy research (90 papers) and Chronic Lymphocytic Leukemia Research (60 papers). Christian Klein collaborates with scholars based in Switzerland, Germany and United States. Christian Klein's co-authors include Lyubomir T. Vassilev, U. Kammlott, Bradford Graves, Binh Thanh Vu, Christine Lukacs, Nader Fotouhi, Frank Podlaski, Norman Kong, Zoran Filipovic and Emily A. Liu and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Christian Klein

335 papers receiving 15.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

2004 3.7k citations Christian Klein et al. profile →
A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade

2018 733 citations Daniela S. Thommen, Petra Herzig et al. profile →
The present and future of bispecific antibodies for cancer therapy

2024 204 citations Christian Klein et al. profile →
Ångström-resolution fluorescence microscopy

2023 156 citations Christian Klein et al. profile →

Peers

Countries citing papers authored by Christian Klein

Since Specialization

Citations

This map shows the geographic impact of Christian Klein's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christian Klein with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christian Klein more than expected).

Fields of papers citing papers by Christian Klein

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christian Klein. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christian Klein. The network helps show where Christian Klein may publish in the future.

Co-authorship network of co-authors of Christian Klein

This figure shows the co-authorship network connecting the top 25 collaborators of Christian Klein. A scholar is included among the top collaborators of Christian Klein based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christian Klein. Christian Klein is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	ESG as risk factor 2025 ·Journal of Asset Management ·(unknown), Christian Klein, Bernhard Zwergel	3
2	Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment 2025 ·Journal for ImmunoTherapy of Cancer ·Jacob Gadwa, Justin Yu, Miles Piper, Michael W. Knitz, Laurel B. Darragh, (unknown), (unknown), Jessica I. Beynor, (unknown), (unknown), (unknown), Diemmy Nguyen, (unknown), Anthony J. Saviola, (unknown), (unknown), (unknown), Christian Klein, Maria Amann, Sana D. Karam	1
3	P179 CD19hi B cells express T-bet and display activated metabolism and function in rheumatoid arthritis and systemic lupus erythematosus patient samples 2024 ·Lara D. Veeken ·(unknown), Maria Leandro, Mark S. Cragg, Florian Kollert, Franz Schuler, David Isenberg, Arne N. Akbar, Christian Klein, Venkat Reddy	1
4	ANG2 Blockade Diminishes Proangiogenic Cerebrovascular Defects Associated With Models of Hereditary Hemorrhagic Telangiectasia 2023 ·Arteriosclerosis Thrombosis and Vascular Biology ·(unknown), (unknown), Aya Nomura-Kitabayashi, Pallavi Chandakkar, (unknown), (unknown), (unknown), Jia Fan, Helen M. Arthur, Christoph Ullmer, Christian Klein, Philippe Marambaud, Stryder M. Meadows	8
5	In Vivo Syngeneic Tumor Models with Acquired Resistance to Anti–PD-1/PD-L1 Therapies 2022 ·Cancer Immunology Research ·(unknown), (unknown), (unknown), Anne Wierinckx, (unknown), Kamel Chettab, (unknown), (unknown), (unknown), Fabian Birzele, Elsa Kress, Lars Petter Jordheim, Christian Klein, Eva‐Laure Matera, Charles Dumontet	18
6	Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors 2022 ·Journal for ImmunoTherapy of Cancer ·Sophia Stock, Mohamed-Reda Benmebarek, (unknown), (unknown), Christian Jöst, Kay‐Gunnar Stubenrauch, J. Benz, Anne Freimoser–Grundschober, Ekkehard Moessner, Pablo Umaña, Marion Subklewe, Stefan Endres, Christian Klein, Sebastian Kobold	19
7	A Novel Approach for Quantifying the Pharmacological Activity of T-Cell Engagers Utilizing In Vitro Time Course Experiments and Streamlined Data Analysis 2021 ·The AAPS Journal ·(unknown), (unknown), Meric Ovacik, Christian Pohl, Sylvia Herter, Tina Weinzierl, Tanja Fauti, Christian Klein, Thorsten Lehr, Marina Bacac, Antje‐Christine Walz	4
8	Calcium Channel Blockers Impair the Antitumor Activity of Anti-CD20 Monoclonal Antibodies by Blocking EGR-1 Induction 2020 ·Molecular Cancer Therapeutics ·(unknown), (unknown), Kamel Chettab, (unknown), Marie Potier‐Cartereau, Lars Petter Jordheim, Catherine Thiéblemont, (unknown), Christian Klein, Charles Dumontet	4
9	Prognostic Impact of Natural Killer Cell Count in Follicular Lymphoma and Diffuse Large B-cell Lymphoma Patients Treated with Immunochemotherapy 2019 ·Clinical Cancer Research ·Magdalena Klánová, Mikkel Z. Oestergaard, Marek Trněný, Wolfgang Hiddemann, Robert Marcus, Laurie H. Sehn, Umberto Vitolo, Alexandra Bazeos, Valentin Goede, Harald Zeuner, Andrea Knapp, Deniz Şahin, (unknown), Christopher R. Bolen, Andrés F. Cardona, Christian Klein, Jeffrey M. Venstrom, Tina Nielsen, Günter Fingerle‐Rowson	54
10	Trabectedin Reveals a Strategy of Immunomodulation in Chronic Lymphocytic Leukemia 2019 ·Cancer Immunology Research ·(unknown), Ronghua Zhang, Cristina Ivan, Giovanni Galletti, Karen Clise-Dwyer, Federica Barbaglio, Lydia Scarfò, Miguel Aracil, Christian Klein, William G. Wierda, William Plunkett, Federico Caligaris‐Cappio, Varsha Gandhi, Michael J. Keating, Maria Teresa Sabrina Bertilaccio	38
11	Prediction of the Optimal Dosing Regimen Using a Mathematical Model of Tumor Uptake for Immunocytokine-Based Cancer Immunotherapy 2018 ·Clinical Cancer Research ·Benjamin Ribba, Christophe Boetsch, Tapan K. Nayak, Hans Peter Grimm, Jehad Charo, Stefan Evers, Christian Klein, Jean Tessier, (unknown), Alex Phipps, Pavel Pisa, Volker Teichgräber	56
12	Human neutrophils mediate trogocytosis rather than phagocytosis of CLL B cells opsonized with anti-CD20 antibodies 2017 ·Blood ·Rut Valgardsdottir, Irene Cattaneo, Christian Klein, Martino Introna, Marina Figliuzzi, Josée Golay	80
13	A New Class of Bifunctional Major Histocompatibility Class I Antibody Fusion Molecules to Redirect CD8 T Cells 2016 ·Molecular Cancer Therapeutics ·(unknown), Eike Hoffmann, Sabine Imhof-Jung, Cornelia Fischer, (unknown), Guy Georges, Christian Klein, Hendrik Knoetgen	17
14	In Vivo Fluorescence Imaging of the Activity of CEA TCB, a Novel T-Cell Bispecific Antibody, Reveals Highly Specific Tumor Targeting and Fast Induction of T-Cell–Mediated Tumor Killing 2016 ·Clinical Cancer Research ·Steffi Lehmann, (unknown), (unknown), Johannes Sam, Sara Colombetti, Tanja Fauti, Linda Fahrni, Teilo Schaller, Anne Freimoser–Grundschober, Jörg Zielonka, Szymon Stoma, Markus Rudin, Christian Klein, Pablo Umaña, Christian Gerdes, Marina Bacac	53
15	Committing Cytomegalovirus-Specific CD8 T Cells to Eliminate Tumor Cells by Bifunctional Major Histocompatibility Class I Antibody Fusion Molecules 2015 ·Cancer Immunology Research ·(unknown), Victor Levitsky, Eike Hoffmann, Guy Georges, Olaf Mundigl, Christian Klein, Hendrik Knoetgen	17
16	Progression of Lung Cancer Is Associated with Increased Dysfunction of T Cells Defined by Coexpression of Multiple Inhibitory Receptors 2015 ·Cancer Immunology Research ·Daniela S. Thommen, Jens Schreiner, Philipp Müller, Petra Herzig, Andreas Roller, Anton Belousov, Pablo Umaña, Pavel Pisa, Christian Klein, Marina Bacac, (unknown), Wolfgang Moersig, Spasenija Savic Prince, Victor Levitsky, Vaios Karanikas, Didier Lardinois, Alfred Zippelius	315
17	Ang-2-VEGF-A CrossMab, a Novel Bispecific Human IgG1 Antibody Blocking VEGF-A and Ang-2 Functions Simultaneously, Mediates Potent Antitumor, Antiangiogenic, and Antimetastatic Efficacy 2013 ·Clinical Cancer Research ·Yvonne Kienast, Christian Klein, Werner Scheuer, (unknown), Erica Lorenzon, Dirk Bernicke, Frank Herting, Sidney Yu, (unknown), Laurent Martarello, Christian Gassner, (unknown), (unknown), Hellmut G. Augustin, Markus Thomas	143
18	Preclinical Studies on the Mechanism of Action and the Anti-Lymphoma Activity of the Novel Anti-CD20 Antibody GA101 2011 ·Molecular Cancer Therapeutics ·Stéphane Dalle, Lina Reslan, (unknown), (unknown), Frank Herting, Adriana Pleșa, Thomas Friess, Pablo Umaña, Christian Klein, Charles Dumontet	97
19	Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies 2011 ·Proceedings of the National Academy of Sciences ·Wolfgang Schaefer, Jörg T. Regula, Monika Bähner, Jürgen Schanzer, Rebecca Croasdale, Harald Dürr, Christian Gassner, Guy Georges, Hubert Kettenberger, Sabine Imhof-Jung, Manfred Schwaiger, Kay Stubenrauch, Claudio Sustmann, Markus Thomas, Werner Scheuer, Christian Klein	334
20	Candidate Biomarkers of Response to an Experimental Cancer Drug Identified through a Large-scale RNA Interference Genetic Screen 2009 ·Clinical Cancer Research ·Jasper Mullenders, Wolfgang von der Saal, (unknown), (unknown), (unknown), Roderick L. Beijersbergen, Georg Tiefenthaler, Christian Klein, René Bernards	8

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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