Sebastian Frechen

1.2k total citations
43 papers, 907 citations indexed

About

Sebastian Frechen is a scholar working on Pharmacology, Pediatrics, Perinatology and Child Health and Oncology. According to data from OpenAlex, Sebastian Frechen has authored 43 papers receiving a total of 907 indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Pharmacology, 13 papers in Pediatrics, Perinatology and Child Health and 9 papers in Oncology. Recurrent topics in Sebastian Frechen's work include Pharmacogenetics and Drug Metabolism (25 papers), Analytical Chemistry and Chromatography (5 papers) and Drug Transport and Resistance Mechanisms (5 papers). Sebastian Frechen is often cited by papers focused on Pharmacogenetics and Drug Metabolism (25 papers), Analytical Chemistry and Chromatography (5 papers) and Drug Transport and Resistance Mechanisms (5 papers). Sebastian Frechen collaborates with scholars based in Germany, France and United States. Sebastian Frechen's co-authors include Thorsten Lehr, Thomas Wendl, Thomas Eißing, Nina Hanke, Uwe Fuhr, Hannah Britz, Raymond Voltz, Jan Gaertner, Amin Rostami‐Hodjegan and Christoph Ostgathe and has published in prestigious journals such as Journal of Clinical Oncology, European Heart Journal and Antimicrobial Agents and Chemotherapy.

In The Last Decade

Sebastian Frechen

42 papers receiving 898 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sebastian Frechen Germany	19	326	217	212	188	144	43	907
Eva Gil Berglund Sweden	13	466 1.4×	259 1.2×	385 1.8×	154 0.8×	79 0.5×	19	1.1k
Shirley M. Tsunoda United States	17	461 1.4×	261 1.2×	316 1.5×	126 0.7×	77 0.5×	47	1.1k
Antonio J. Carcas Spain	22	339 1.0×	306 1.4×	173 0.8×	353 1.9×	79 0.5×	116	1.7k
Ylva Böttiger Sweden	21	457 1.4×	329 1.5×	255 1.2×	119 0.6×	80 0.6×	53	1.4k
Juri Solodenko Germany	9	190 0.6×	206 0.9×	120 0.6×	133 0.7×	127 0.9×	14	709
Rebecca A. Boyd United States	21	241 0.7×	255 1.2×	264 1.2×	133 0.7×	50 0.3×	34	2.4k
Elizabeth Ludwig United States	19	208 0.6×	173 0.8×	119 0.6×	239 1.3×	98 0.7×	59	1.1k
Alice Ke United States	16	228 0.7×	240 1.1×	208 1.0×	80 0.4×	200 1.4×	30	755
Daniel S. Streetman United States	19	533 1.6×	247 1.1×	206 1.0×	193 1.0×	78 0.5×	36	1.2k
Lisa M. Almond United Kingdom	17	327 1.0×	259 1.2×	324 1.5×	142 0.8×	79 0.5×	34	1.1k

Countries citing papers authored by Sebastian Frechen

Since Specialization

Citations

This map shows the geographic impact of Sebastian Frechen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sebastian Frechen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sebastian Frechen more than expected).

Fields of papers citing papers by Sebastian Frechen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sebastian Frechen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sebastian Frechen. The network helps show where Sebastian Frechen may publish in the future.

Co-authorship network of co-authors of Sebastian Frechen

This figure shows the co-authorship network connecting the top 25 collaborators of Sebastian Frechen. A scholar is included among the top collaborators of Sebastian Frechen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sebastian Frechen. Sebastian Frechen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Vertzoni, Maria, Sebastian Frechen, Juri Solodenko, et al.. (2025). Development of a novel physiologically based biopharmaceutics modeling (PBBM) framework using the open systems pharmacology suite, part 2: in vivo pharmacokinetic modeling of vericiguat. European Journal of Pharmaceutical Sciences. 212. 107189–107189. 1 indexed citations

Frechen, Sebastian, et al.. (2025). Development of a novel physiologically based biopharmaceutics modeling (PBBM) framework using the open systems pharmacology suite, part 1: in vitro modeling of vericiguat. European Journal of Pharmaceutical Sciences. 212. 107164–107164. 3 indexed citations

Selzer, Dominik, Donato Teutonico, Juri Solodenko, et al.. (2025). A Comprehensive CYP2D6 Drug–Drug–Gene Interaction Network for Application in Precision Dosing and Drug Development. Clinical Pharmacology & Therapeutics. 117(6). 1718–1731. 3 indexed citations

Dallmann, André, et al.. (2024). PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first‐pass metabolism?. CPT Pharmacometrics & Systems Pharmacology. 14(1). 130–141.

Willmann, Stefan, Adam Lloyd, Rupert Austin, et al.. (2024). Population pharmacokinetic–pharmacodynamic model of elinzanetant based on integrated clinical phase I and II data. CPT Pharmacometrics & Systems Pharmacology. 13(12). 2137–2149. 1 indexed citations

Selzer, Dominik, Donato Teutonico, Sebastian Frechen, et al.. (2023). Physiologically‐based pharmacokinetic modeling of quinidine to establish a CYP3A4, P‐gp, and CYP2D6 drug–drug–gene interaction network. CPT Pharmacometrics & Systems Pharmacology. 12(8). 1143–1156. 9 indexed citations

Frechen, Sebastian, Ibrahim Ince, André Dallmann, et al.. (2023). Applied physiologically‐based pharmacokinetic modeling to assess uridine diphosphate‐glucuronosyltransferase‐mediated drug–drug interactions for Vericiguat. CPT Pharmacometrics & Systems Pharmacology. 13(1). 79–92. 7 indexed citations

Selzer, Dominik, Matthias Schwab, Donato Teutonico, et al.. (2023). Physiologically based pharmacokinetic modeling of tacrolimus for food–drug and CYP3A drug–drug–gene interaction predictions. CPT Pharmacometrics & Systems Pharmacology. 12(5). 724–738. 11 indexed citations

Frechen, Sebastian & Amin Rostami‐Hodjegan. (2022). Quality Assurance of PBPK Modeling Platforms and Guidance on Building, Evaluating, Verifying and Applying PBPK Models Prudently under the Umbrella of Qualification: Why, When, What, How and By Whom?. Pharmaceutical Research. 39(8). 1733–1748. 38 indexed citations

10.

Li, Xia, Sebastian Frechen, Thorsten Lehr, et al.. (2019). A Physiologically Based Pharmacokinetic Model of Voriconazole Integrating Time-Dependent Inhibition of CYP3A4, Genetic Polymorphisms of CYP2C19 and Predictions of Drug–Drug Interactions. Clinical Pharmacokinetics. 59(6). 781–808. 46 indexed citations

11.

Hanke, Nina, Sebastian Frechen, Thomas Eißing, et al.. (2019). Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug–Drug–Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole. Clinical Pharmacokinetics. 58(12). 1595–1607. 41 indexed citations

12.

Hanke, Nina, Hannah Britz, Sebastian Frechen, et al.. (2016). Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug–Drug Interactions and Co-medication Regimens. The AAPS Journal. 19(1). 298–312. 33 indexed citations

13.

Braun, Tina, Sebastian Frechen, S. Hüttner, et al.. (2016). Comparison of Pantoprazole Concentrations in Simultaneous Cerebrospinal Fluid and Serum Samples. Pharmacology. 98(1-2). 70–72. 2 indexed citations

14.

Suleiman, Ahmed A., Sebastian Frechen, Matthias Scheffler, et al.. (2015). A Modeling and Simulation Framework for Adverse Events in Erlotinib-Treated Non-Small-Cell Lung Cancer Patients. The AAPS Journal. 17(6). 1483–1491. 9 indexed citations

15.

Frechen, Sebastian, et al.. (2015). Population pharmacokinetic and pharmacodynamic modeling of epinephrine administered using a mobile inhaler. Drug Metabolism and Pharmacokinetics. 30(6). 391–399. 7 indexed citations

16.

Fuhr, Uwe, et al.. (2015). Development and validation of an in vitro, seven-in-one human cytochrome P450 assay for evaluation of both direct and time-dependent inhibition. Journal of Pharmacological and Toxicological Methods. 77. 66–75. 13 indexed citations

17.

Suleiman, Ahmed A., Sebastian Frechen, Matthias Scheffler, et al.. (2014). Modeling Tumor Dynamics and Overall Survival in Advanced Non–Small-Cell Lung Cancer Treated with Erlotinib. Journal of Thoracic Oncology. 10(1). 84–92. 14 indexed citations

18.

Frechen, Sebastian, et al.. (2012). Drug Interactions in Dying Patients. Drug Safety. 35(9). 745–758. 28 indexed citations

19.

Gaertner, Jan, Juergen Wolf, Sebastian Frechen, et al.. (2011). Recommending early integration of palliative care — does it work?. Supportive Care in Cancer. 20(3). 507–513. 34 indexed citations

20.

Gaertner, Jan, Juergen Wolf, Sebastian Frechen, et al.. (2010). Implementing WHO Recommendations for Palliative Care into Routine Lung Cancer Therapy: A Feasibility Project. Journal of Palliative Medicine. 13(6). 727–732. 26 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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