Thomas C. Hamilton

17.2k citations

188 papers · 14.4k indexed · 6 hit papers · h-index 65

Impact in

Reproductive Medicine top 0.2%
- Ovarian cancer diagnosis and treatment
Oncology top 0.5%
- Drug Transport and Resistance Mechanisms
- Metal complexes synthesis and properties

Papers in

Reproductive Medicine 52
- Ovarian cancer diagnosis and treatment 52
Biochemistry 23
- Sulfur Compounds in Biology 11

Co-authors: Robert F. Ozols Andrew K. Godwin Robert C. Young Steven W. Johnson Russell J. Schilder A.H. Weston Karen R. Grotzinger Lainie P. Martin
Journals: Gynecologic Oncology (12 papers)British Journal of Pharmacology (11 papers)Biochemical Pharmacology (10 papers)Cancer (8 papers)European Journal of Pharmacology (7 papers)
Partner nations: United States United Kingdom Canada

In The Last Decade

Thomas C. Hamilton

187 papers receiving 13.9k citations

Hit Papers

6 papers align trajectories log scale

Platinum Resistance: The Role of DNA Repair Pathways 2008 · 604 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2008 Clinical Cancer Research
1992 Proceedings of the National Academy of Sciences
1992 Proceedings of the National Academy of Sciences
1987 PubMed
1985 Biochemical Pharmacology
1983 PubMed

Peers

Countries citing papers authored by Thomas C. Hamilton

Since Specialization

Citations

This map shows the geographic impact of Thomas C. Hamilton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas C. Hamilton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas C. Hamilton more than expected).

Fields of papers citing papers by Thomas C. Hamilton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas C. Hamilton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas C. Hamilton. The network helps show where Thomas C. Hamilton may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Thomas C. Hamilton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Thomas C. Hamilton Line = papers co-authored together Thomas C. Hamilton links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Expression of Activated PIK3CA in Ovarian Surface Epithelium Results in Hyperplasia but Not Tumor Formation PLoS ONE ·Shun Liang, Nuo Yang, Yue Pan, Shan Deng, Xiaojuan Lin, Xiaojun Yang, Dionyssios Katsaros, Katherine F. Roby, Thomas C. Hamilton, Denise C. Connolly, George Coukos, Lin Zhang	2009	28
2	RAD001 (Everolimus) Delays Tumor Onset and Progression in a Transgenic Mouse Model of Ovarian Cancer Cancer Research ·Seiji Mabuchi, Deborah A. Altomare, Denise C. Connolly, Andres J. Klein–Szanto, Samuel Litwin, Matthew K. Hoelzle, Harvey H. Hensley, Thomas C. Hamilton, Joseph R. Testa	2007	156
3	Magnetic resonance imaging for detection and determination of tumor volume in a genetically engineered mouse model of ovarian cancer Cancer Biology & Therapy ·Harvey H. Hensley, Bridget A. Quinn, Ronald L. Wolf, Samuel Litwin, Seiji Mabuchi, Stephen J. Williams, Jorge Costa-Fernandez, Thomas C. Hamilton, Denise C. Connolly	2007	46
4	Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells British Journal of Cancer ·David W. Roberts, Jonathan Schick, Susan R. Conway, S. Biade, Paul B. Laub, James Stevenson, Thomas C. Hamilton, Peter J. O’Dwyer, Steven W. Johnson	2005	121
5	Characterization of a Carcinogenesis Rat Model of Ovarian Preneoplasia and Neoplasia Cancer Research ·Sherri L. Stewart, Troy D. Querec, J R Allan, U. Vijitha, Rudi Bao, James S. Babb, Bulgansyah Ritonga, M. Otljanska, 帅晓珊, Andres J. Klein–Szanto, Thomas C. Hamilton, Christos Patriotis	2004	52
6	Disabled-2 Is Essential for Endodermal Cell Positioning and Structure Formation during Mouse Embryogenesis Developmental Biology ·Dong‐Hua Yang, Elizabeth R. Smith, Isabelle Roland, Zejuan Sheng, Junqi He, William Martin, Thomas C. Hamilton, J. David Lambeth, Xiang‐Xi Xu	2002	140
7	Basic research: how much do we know, and what are we likely to learn about ovarian cancer in the near future? Annals of Oncology ·Thomas C. Hamilton, Jonathan S. Berek, S.B. Kaye	1999	4
8	The role of hMLH1, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: correlation with replicative bypass of platinum-DNA adducts. PubMed ·Alexandra Vaisman, Andrés Rodríguez Gallego, Asad Umar, Thomas A. Kunkel, John I. Risinger, J. Carl Barrett, Thomas C. Hamilton, Stephen G. Chaney	1998	246
9	Clinical studies of reversal of drug resistance based on glutathione Chemico-Biological Interactions ·Paula Calvert, Kang-Shen Yao, Thomas C. Hamilton, Peter J. O’Dwyer	1998	98
10	Comparison of the Cardiovascular Effects of the Novel 5-HT1B/1D Receptor Agonist, SB 209509 (VML251), and Sumatriptan in Dogs Journal of Cardiovascular Pharmacology ·Andrew A. Parsons, Stephen Parker, Pravin Raval, Colin A. Campbell, Vahn A. Lewis, В Г Гуляев, Andrea Hunter, Thomas C. Hamilton, Frank D. King	1997	24
11	Identification of a zinc-finger gene at 6q25: a chromosomal region implicated in development of many solid tumors Oncogene ·Abbas Abdollahi, David W. Roberts, Andrew K. Godwin, D. Schultz, Gonosuke Sonoda, Joseph R. Testa, Thomas C. Hamilton	1997	93
12	Increased DT-diaphorase expression and cross-resistance to mitomycin C in a series of cisplatin-resistant human ovarian cancer cell lines Biochemical Pharmacology ·Peter J. O’Dwyer, Raymond P. Perez, Kang-Shen Yao, Shilpa Nargund, Thomas C. Hamilton	1996	12
13	Expression of two mucin antigens in cultured human ovarian surface epithelium: Influence of a family hostory of ovarian cancer American Journal of Obstetrics and Gynecology ·Nelly Auersperg, Sarah Maines‐Bandiera, Justin Amevor, Henry T. Lynch, Andrew K. Godwin, Thomas C. Hamilton	1995	48
14	Alkylating agents and immunotoxins exert synergistic cytotoxic activity against ovarian cancer cells. Mechanism of action. Journal of Clinical Investigation ·安迪黄, Kathy O'Briant, Feng Xu, Thomas C. Hamilton, Robert F. Ozols, Robert C. Bast	1993	16
15	Potassium channel modulators : pharmacological, molecular and clinical aspects A.H. Weston, Thomas C. Hamilton	1992	16
16	Resistance to alkylating agents and cisplatin: Insights from ovarian carcinoma model systems Pharmacology & Therapeutics ·Raymond P. Perez, Thomas C. Hamilton, Robert F. Ozols	1990	66
17	Inhibition by glibenclamide of the vasorelaxant action of cromakalim in the rat British Journal of Pharmacology ·Robin E. Buckingham, Thomas C. Hamilton, David Howlett, O. Adeponle, Campbell Wilson	1989	107
18	Estrogen and Anti-Estrogen Effects on the Growth of Human Epithelial Ovarian Cancer In Vitro American Journal of Obstetrics and Gynecology ·John D. Nash, Robert F. Ozols, John F. Smyth, Thomas C. Hamilton	1989	74
19	Multidrug resistance in ovarian cancer Cancer ·Antonio Tito Fojo, Thomas C. Hamilton, Robert C. Young, R F Ozols	1987	78
20	Modulation of induced resistance to adriamycin in two human breast cancer cell lines with tamoxifen or perhexiline maleate 良子上坂, Thomas C. Hamilton	1986	1

About Thomas C. Hamilton

Thomas C. Hamilton is a scholar working on Reproductive Medicine, Biochemistry, Molecular Biology, Oncology and Cancer Research, having authored 188 papers that have together received 14.4k indexed citations. Recurring topics across this work include Ovarian cancer diagnosis and treatment (52 papers), Reproductive Biology and Fertility (12 papers), Drug Transport and Resistance Mechanisms (11 papers), Sulfur Compounds in Biology (11 papers), Receptor Mechanisms and Signaling (10 papers), Virus-based gene therapy research (10 papers), Chemotherapy-induced organ toxicity mitigation (9 papers) and Genomics, phytochemicals, and oxidative stress (9 papers). The work is most often cited by research in Reproductive Medicine (2.3k citations), Oncology (4.6k citations), Biochemistry (1.0k citations), Molecular Biology (8.4k citations) and Cancer Research (1.7k citations). Thomas C. Hamilton has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include Robert F. Ozols, Andrew K. Godwin, Robert C. Young, Steven W. Johnson, Russell J. Schilder, A.H. Weston, Karen R. Grotzinger, Lainie P. Martin, Karen G. Louie and Wilma M. McKoy. Their work appears in journals such as Gynecologic Oncology, British Journal of Pharmacology, Biochemical Pharmacology, Cancer and European Journal of Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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