Theo A. Berkhout

2.3k citations

28 papers · 1.9k indexed · 1 hit paper · h-index 20

Co-authors: Andreas Ludwig Pieter H.E. Groot Stefan Rose‐John Christian Hundhausen Neil Broadway Dieter Hartmann Paul Säftig Kitty Moores
Topics: Chemokine receptors and signaling (10 papers)Lipid Membrane Structure and Behavior (7 papers)Cell Adhesion Molecules Research (6 papers)
Cited by: Immunology and Allergy Immunology Oncology
Journals: Journal of Biological Chemistry Blood The Journal of Immunology
Partner nations: United Kingdom United States Netherlands

In The Last Decade

Theo A. Berkhout

28 papers receiving 1.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion

2003 588 citations Christian Hundhausen, Theo A. Berkhout et al. profile →

Peers

Countries citing papers authored by Theo A. Berkhout

Since Specialization

Citations

This map shows the geographic impact of Theo A. Berkhout's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Theo A. Berkhout with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Theo A. Berkhout more than expected).

Fields of papers citing papers by Theo A. Berkhout

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Theo A. Berkhout. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Theo A. Berkhout. The network helps show where Theo A. Berkhout may publish in the future.

Co-authorship network of co-authors of Theo A. Berkhout

This figure shows the co-authorship network connecting the top 25 collaborators of Theo A. Berkhout. A scholar is included among the top collaborators of Theo A. Berkhout based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Theo A. Berkhout. Theo A. Berkhout is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The Transmembrane CXC-Chemokine Ligand 16 Is Induced by IFN-γ and TNF-α and Shed by the Activity of the Disintegrin-Like Metalloproteinase ADAM10 2004 ·The Journal of Immunology ·Sören Abel,Christian Hundhausen,Rolf Mentlein,Alexander Schulte,Theo A. Berkhout,Neil Broadway,Dieter Hartmann,(unknown),Sebastian Dietrich,(unknown),Bjoern Schuster,(unknown),Paul Säftig,Stefan Rose‐John,Andreas Ludwig	347
2	CCR2: Characterization of the Antagonist Binding Site from a Combined Receptor Modeling/Mutagenesis Approach 2003 ·Journal of Medicinal Chemistry ·Theo A. Berkhout,Frank E. Blaney,Angela Bridges,David G. Cooper,Ian T. Forbes,Andrew D. Gribble,Pieter H.E. Groot,A. Hardy,Robert J. Ife,Rejbinder Kaur,Kitty Moores,(unknown),(unknown),Jason Witherington	75
3	Fractalkine Is Expressed by Smooth Muscle Cells in Response to IFN-γ and TNF-α and Is Modulated by Metalloproteinase Activity 2002 ·The Journal of Immunology ·Andreas Ludwig,Theo A. Berkhout,Kitty Moores,Pieter H.E. Groot,Gayle A. Chapman	124
4	Conformationally Restricted Indolopiperidine Derivatives as Potent CCR2B Receptor Antagonists 2001 ·Bioorganic & Medicinal Chemistry Letters ·Jason Witherington,Vincent Bordas,(unknown),Ian T. Forbes,Andrew D. Gribble,Robert J. Ife,Theo A. Berkhout,(unknown),Pieter H.E. Groot	35
5	CCR2B receptor antagonists: conversion of a weak HTS hit to a potent lead compound 2000 ·Bioorganic & Medicinal Chemistry Letters ·Ian T. Forbes,David G. Cooper,(unknown),Deirdre M. B. Hickey,Robert J. Ife,(unknown),Martin L. Stockley,Theo A. Berkhout,(unknown),Pieter H.E. Groot,Kitty Moores	41
6	Selective binding of the truncated form of the chemokine CKβ8 (25–99) to CC chemokine receptor 1 (CCR1) 2000 ·Biochemical Pharmacology ·Theo A. Berkhout,(unknown),Paula González,(unknown),Kitty Moores,Colin H. Macphee,John R. White,Pieter H.E. Groot	12
7	The role of fractalkine in the recruitment of monocytes to the endothelium 2000 ·European Journal of Pharmacology ·Gayle A. Chapman,Kitty Moores,(unknown),Theo A. Berkhout,Lisa Patel,(unknown),Colin H. Macphee,Brian R. Stewart	81
8	Identification of a Truncated Form of the CC Chemokine CKβ-8 Demonstrating Greatly Enhanced Biological Activity 1998 ·The Journal of Immunology ·Colin H. Macphee,Edward R. Appelbaum,Kyung Johanson,Kitty Moores,(unknown),(unknown),Theo A. Berkhout,Mary Brawner,Pieter H.E. Groot,Kevin O’Donnell,Daniel J. O’Shannessy,(unknown),John R. White	23
9	Identification of a truncated form of the CC chemokine CK beta-8 demonstrating greatly enhanced biological activity. 1998 ·PubMed ·Colin H. Macphee,Edward R. Appelbaum,Kyung Johanson,Kitty Moores,(unknown),James A. Fornwald,Theo A. Berkhout,Mary Brawner,Pieter H.E. Groot,Kevin O’Donnell,Daniel J. O’Shannessy,G. Kenneth Scott,John R. White	22
10	Cloning, in Vitro Expression, and Functional Characterization of a Novel Human CC Chemokine of the Monocyte Chemotactic Protein (MCP) Family (MCP-4) That Binds and Signals through the CC Chemokine Receptor 2B 1997 ·Journal of Biological Chemistry ·Theo A. Berkhout,Henry M. Sarau,Kitty Moores,John R. White,Nabil A. Elshourbagy,Edward R. Appelbaum,(unknown),(unknown),(unknown),James J. Foley,Dulcie B. Schmidt,(unknown),Dean E. McNulty,(unknown),Kevin O’Donnell,Daniel J. O’Shannessy,Miller O. Scott,Pieter H.E. Groot,Colin H. Macphee	88
11	SR-12813 lowers plasma cholesterol in beagle dogs by decreasing cholesterol biosynthesis 1997 ·Atherosclerosis ·Theo A. Berkhout,(unknown),Brian Jackson,John Yates,Neil Pearce,Pieter H.E. Groot,(unknown),Eric J. Niesor,William Kerns,Keith E. Suckling	19
12	The Novel Cholesterol-lowering Drug SR-12813 Inhibits Cholesterol Synthesis via an Increased Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase 1996 ·Journal of Biological Chemistry ·Theo A. Berkhout,(unknown),Dilip D. Patel,C. Bentzen,Eric J. Niesor,Brian Jackson,Keith E. Suckling	35
13	Effects of a novel lanosterol 14 alpha-demethylase inhibitor on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in Hep G2 cells. 1991 ·Journal of Biological Chemistry ·Ruth J. Mayer,Jerry L. Adams,M.J. Bossard,Theo A. Berkhout	31
14	The effect of (−)-hydroxycitrate on the activity of the low-density-lipoprotein receptor and 3-hydroxy-3-methylglutaryl-CoA reductase levels in the human hepatoma cell line Hep G2 1990 ·Biochemical Journal ·Theo A. Berkhout,Louis M. Havekes,Neil Pearce,Pieter H.E. Groot	73
15	Preferential association of apocytochrome c with negatively charged phospholipids in mixed model membranes 1986 ·Biochimica et Biophysica Acta (BBA) - Biomembranes ·(unknown),Theo A. Berkhout,(unknown),Derek Marsh,Ben de Kruijff	38
16	Coupling of photoactivatable glycolipid probes to apolipoproteins A-I and A-II in human high density lipoproteins 2 and 3. 1985 ·Journal of Lipid Research ·Theo A. Berkhout,Pieter H.E. Groot,(unknown),K.W.A. Wirtz	2
17	Static and time-resolved fluorescence studies of fluorescent phosphatidylcholine bound to the phosphatidylcholine-transfer protein of bovine liver 1984 ·Biochemistry ·Theo A. Berkhout,Antonie J. W. G. Visser,K.W.A. Wirtz	30
18	Labeling of phospholipids in vesicles and human erythrocytes by photoactivable fatty acid derivatives 1984 ·European Journal of Biochemistry ·Theo A. Berkhout,(unknown),K.W.A. Wirtz	12
19	Identification of the Lipid-Binding Site of Phosphatidylcholine-Transfer Protein with Phosphatidylcholine Analogs Containing Photactivable Carbene Precursors 1983 ·European Journal of Biochemistry ·Jan Westerman,K.W.A. Wirtz,Theo A. Berkhout,(unknown),Ramachandran Radhakrishnan,H. G. Khorana	41
20	Analysis of histones from the yeast Saccharomyces carlsbergensis 1979 ·Biochemical Journal ·Albert Pastink,Theo A. Berkhout,(unknown),R.J. Planta	10

About Theo A. Berkhout

Theo A. Berkhout is a scholar working on Immunology and Allergy, Oncology and Biochemistry, having authored 28 papers that have together received 1.9k indexed citations. Recurring topics across this work include Chemokine receptors and signaling (10 papers), Lipid Membrane Structure and Behavior (7 papers) and Cell Adhesion Molecules Research (6 papers). The work is most often cited by research in Immunology and Allergy (299 citations), Immunology (747 citations) and Oncology (923 citations). Theo A. Berkhout has collaborated with scholars based in United Kingdom, United States and Netherlands. Frequent co-authors include Andreas Ludwig, Pieter H.E. Groot, Stefan Rose‐John, Christian Hundhausen, Neil Broadway, Dieter Hartmann, Paul Säftig, Kitty Moores, Karl‐Josef Kallen and Falk Fahrenholz. Their work appears in journals such as Journal of Biological Chemistry, Blood and The Journal of Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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