T.D. Bethke

3.9k total citations · 1 hit paper
26 papers, 1.6k citations indexed

About

T.D. Bethke is a scholar working on Molecular Biology, Pulmonary and Respiratory Medicine and Analytical Chemistry. According to data from OpenAlex, T.D. Bethke has authored 26 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Molecular Biology, 9 papers in Pulmonary and Respiratory Medicine and 8 papers in Analytical Chemistry. Recurrent topics in T.D. Bethke's work include Phosphodiesterase function and regulation (12 papers), Analytical Methods in Pharmaceuticals (8 papers) and Asthma and respiratory diseases (6 papers). T.D. Bethke is often cited by papers focused on Phosphodiesterase function and regulation (12 papers), Analytical Methods in Pharmaceuticals (8 papers) and Asthma and respiratory diseases (6 papers). T.D. Bethke collaborates with scholars based in Germany, Netherlands and Austria. T.D. Bethke's co-authors include Dirk Bredenbröker, Klaus F. Rabe, Peter J. Sterk, Pieter S. Hiemstra, Stefanie A. Gauw, Jeannette J. Hospers, Renate M. Verhoosel, Diana C. Grootendorst, Karl Zech and R. Nave and has published in prestigious journals such as Gastroenterology, CHEST Journal and Journal of Allergy and Clinical Immunology.

In The Last Decade

T.D. Bethke

26 papers receiving 1.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Arzneimittelforschung

2012 1.0k citations T.D. Bethke Der Pneumologe profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
T.D. Bethke Germany	13	469	397	377	175	157	26	1.6k
C. Gary Gairola United States	25	885 1.9×	255 0.6×	268 0.7×	88 0.5×	116 0.7×	89	2.1k
Salvatore Sotgia Italy	31	830 1.8×	417 1.1×	417 1.1×	69 0.4×	150 1.0×	149	2.9k
Françoise Stanke‐Labesque France	26	400 0.9×	262 0.7×	482 1.3×	126 0.7×	239 1.5×	123	2.3k
Keri Wellington New Zealand	26	329 0.7×	414 1.0×	120 0.3×	118 0.7×	153 1.0×	54	1.9k
Adam Szeląg Poland	24	462 1.0×	198 0.5×	160 0.4×	80 0.5×	153 1.0×	128	1.7k
Kenji Matsuyama Japan	24	504 1.1×	123 0.3×	332 0.9×	59 0.3×	161 1.0×	121	1.8k
Yan-Ping Liu China	24	512 1.1×	119 0.3×	341 0.9×	136 0.8×	352 2.2×	107	2.0k
Marc Conti France	28	1.0k 2.2×	220 0.6×	460 1.2×	76 0.4×	240 1.5×	65	3.3k
Brooks M. Hybertson United States	24	799 1.7×	393 1.0×	248 0.7×	107 0.6×	35 0.2×	55	2.1k
Mustafa Birincioğlu Türkiye	18	773 1.6×	129 0.3×	161 0.4×	164 0.9×	157 1.0×	38	1.8k

Countries citing papers authored by T.D. Bethke

Since Specialization

Citations

This map shows the geographic impact of T.D. Bethke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by T.D. Bethke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites T.D. Bethke more than expected).

Fields of papers citing papers by T.D. Bethke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by T.D. Bethke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by T.D. Bethke. The network helps show where T.D. Bethke may publish in the future.

Co-authorship network of co-authors of T.D. Bethke

This figure shows the co-authorship network connecting the top 25 collaborators of T.D. Bethke. A scholar is included among the top collaborators of T.D. Bethke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with T.D. Bethke. T.D. Bethke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bethke, T.D.. (2012). Arzneimittelforschung. Der Pneumologe. 9(5). 380–386. 1040 indexed citations breakdown →

Gleiter, C. H., et al.. (2011). Study investigating pharmacokinetic interaction between theophylline and roflumilast in healthy adults. International Journal of Clinical Pharmacology and Therapeutics. 49(7). 451–460. 6 indexed citations

Bethke, T.D., et al.. (2011). Influence of renal impairment on the pharmacokinetics of oral roflumilast: an open-label, parallel-group, single-center study. International Journal of Clinical Pharmacology and Therapeutics. 49(8). 491–499. 12 indexed citations

Bethke, T.D., et al.. (2011). High absolute bioavailability of the new oral phosphodiesterase-4 inhibitor roflumilast. International Journal of Clinical Pharmacology and Therapeutics. 49(1). 51–57. 13 indexed citations

McCracken, Nigel, et al.. (2011). Lack of pharmacokinetic and pharmacodynamic interactions of roflumilast with (R, S)-warfarin in healthy adult subjects. International Journal of Clinical Pharmacology and Therapeutics. 49(6). 388–396. 7 indexed citations

Grootendorst, Diana C., Stefanie A. Gauw, Renate M. Verhoosel, et al.. (2007). Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD. Thorax. 62(12). 1081–1087. 225 indexed citations

Bethke, T.D., Thomas Gießmann, Kristin Westphal, et al.. (2006). Roflumilast, a once-daily oral phosphodiesterase 4 inhibitor, lacks relevant pharmacokinetic interactions with inhaled salbutamol when co-administered in healthy subjects. International Journal of Clinical Pharmacology and Therapeutics. 44(11). 572–579. 18 indexed citations

Nave, R., Kulasiri A. Gunawardena, Karl Zech, & T.D. Bethke. (2006). Pharmacokinetic disposition of inhaled ciclesonide and its metabolite desisobutyryl-ciclesonide in healthy subjects and patients with asthma are similar. International Journal of Clinical Pharmacology and Therapeutics. 44(1). 1–7. 20 indexed citations

Berg, Andrea von, et al.. (2006). Ciclesonide 160 μg Once Daily is as Effective as Budesonide 400 μg Once Daily in Pediatric Patients with Persistent Asthma. Journal of Allergy and Clinical Immunology. 117(2). S11–S11. 2 indexed citations

10.

Zech, Karl, et al.. (2004). Roflumilast Shows No Pharmacokinetic Interaction with Warfarin in Healthy Subjects. CHEST Journal. 126(4). 804S–804S. 1 indexed citations

11.

Bethke, T.D., et al.. (2004). Long-term Safety of Roflumilast in the Treatment of Chronic Obstructive Pulmonary Disease. CHEST Journal. 126(4). 805S–805S. 1 indexed citations

12.

Zech, Karl, et al.. (2004). Oral, Once-Daily Roflumilast and Its Active N-oxide Metabolite Exhibit Dose-Proportional Pharmacokinetics Between 250μg and 500μg. CHEST Journal. 126(4). 804S–804S. 1 indexed citations

13.

Drollmann, Anton, et al.. (2004). Equivalent pharmacokinetics of the active metabolite of ciclesonide with and without use of a spacer for inhalation. Journal of Allergy and Clinical Immunology. 113(2). S120–S120. 5 indexed citations

14.

Nave, R., Karl Zech, & T.D. Bethke. (2003). Oropharyngeal deposition of inhaled ciclesonide and budesonide in healthy subjects. Journal of Allergy and Clinical Immunology. 111(2). S220–S220. 7 indexed citations

15.

Bethke, T.D., R. Nave, Karl Zech, & Kulasiri A. Gunawardena. (2003). Pharmacokinetics of ciclesonide and its active principle in asthma patients and healthy subjects after single-dose inhalation. Journal of Allergy and Clinical Immunology. 111(2). S217–S217. 6 indexed citations

16.

Dammann, H. G., et al.. (1994). Effects of pantoprazole on endocrine function in healthy male volunteers. Alimentary Pharmacology & Therapeutics. 8(5). 549–554. 13 indexed citations

17.

Bethke, T.D., Wieland Meyer, Wilhelm Schmitz, et al.. (1993). High Selectivity for Inhibition of Phosphodiesterase III and Positive Inotropic Effects of MCI-154 in Guinea Pig Myocardium. Journal of Cardiovascular Pharmacology. 21(6). 847–855. 22 indexed citations

18.

Bethke, T.D., Thomas Eschenhagen, Anna Klimkiewicz, et al.. (1992). Phosphodiesterase inhibition by enoximone in preparations from nonfailing and failing human hearts.. PubMed. 42(4). 437–45. 24 indexed citations

19.

Bethke, T.D., Anna Klimkiewicz, Claudia Kohl, et al.. (1991). Effects of Isomazole on Force of Contraction and Phosphodiesterase Isoenzymes I-IV in Nonfailing and Failing Human Hearts. Journal of Cardiovascular Pharmacology. 18(3). 386–397. 20 indexed citations

20.

Bethke, T.D., et al.. (1991). Effects of the triazolopyrimidine trapidil on force of contraction, beating frequency and phosphodiesterase I--IV activity in guinea-pig hearts.. PubMed. 41(5). 461–8. 6 indexed citations

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