Holger Stark

13.3k total citations · 2 hit papers
370 papers, 10.5k citations indexed

About

Holger Stark is a scholar working on Molecular Biology, Immunology and Organic Chemistry. According to data from OpenAlex, Holger Stark has authored 370 papers receiving a total of 10.5k indexed citations (citations by other indexed papers that have themselves been cited), including 237 papers in Molecular Biology, 210 papers in Immunology and 62 papers in Organic Chemistry. Recurrent topics in Holger Stark's work include Mast cells and histamine (202 papers), Receptor Mechanisms and Signaling (132 papers) and Chemical Synthesis and Analysis (66 papers). Holger Stark is often cited by papers focused on Mast cells and histamine (202 papers), Receptor Mechanisms and Signaling (132 papers) and Chemical Synthesis and Analysis (66 papers). Holger Stark collaborates with scholars based in Germany, France and Poland. Holger Stark's co-authors include Walter Schunack, Xavier Ligneau, Ralf Gutzmer, Ewgenij Proschak, Kerstin Sander, Bassem Sadek, C. Robin Ganellin, Jean‐Charles Schwartz, Tim Kottke and Daniel Merk and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Medicine.

In The Last Decade

Holger Stark

362 papers receiving 10.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors

2015 414 citations Ralf Gutzmer, Holger Stark et al. profile →
Polypharmacology by Design: A Medicinal Chemist’s Perspective on Multitargeting Compounds

2018 353 citations Ewgenij Proschak, Holger Stark et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Holger Stark Germany	51	5.6k	4.4k	1.8k	1.5k	1.3k	370	10.5k
C. Robin Ganellin United Kingdom	41	5.6k 1.0×	4.0k 0.9×	1.5k 0.8×	1.8k 1.2×	1.2k 1.0×	197	10.2k
Rob Leurs Netherlands	71	10.9k 2.0×	8.2k 1.9×	3.8k 2.1×	1.8k 1.2×	1.9k 1.5×	443	19.1k
Walter Schunack Germany	40	4.1k 0.7×	4.0k 0.9×	756 0.4×	964 0.7×	1.5k 1.2×	342	6.7k
Jean‐Charles Schwartz France	63	8.3k 1.5×	4.3k 1.0×	7.3k 4.1×	611 0.4×	2.2k 1.7×	221	15.4k
Heike Wulff United States	62	9.0k 1.6×	1.5k 0.3×	3.2k 1.8×	477 0.3×	1.4k 1.1×	232	13.3k
Joseph A. Beavo United States	72	16.6k 3.0×	2.2k 0.5×	2.9k 1.6×	1.9k 1.3×	490 0.4×	169	22.2k
H. Timmerman Netherlands	35	2.5k 0.4×	2.2k 0.5×	525 0.3×	685 0.5×	736 0.6×	146	4.3k
Miles D. Houslay United Kingdom	88	19.8k 3.6×	1.8k 0.4×	4.4k 2.4×	1.4k 1.0×	314 0.2×	414	25.6k
Evi Kostenis Germany	56	6.3k 1.1×	967 0.2×	3.5k 2.0×	345 0.2×	135 0.1×	195	9.7k
Graeme Milligan United Kingdom	85	21.1k 3.8×	1.7k 0.4×	11.8k 6.6×	403 0.3×	303 0.2×	555	27.7k

Countries citing papers authored by Holger Stark

Since Specialization

Citations

This map shows the geographic impact of Holger Stark's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Holger Stark with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Holger Stark more than expected).

Fields of papers citing papers by Holger Stark

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Holger Stark. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Holger Stark. The network helps show where Holger Stark may publish in the future.

Co-authorship network of co-authors of Holger Stark

This figure shows the co-authorship network connecting the top 25 collaborators of Holger Stark. A scholar is included among the top collaborators of Holger Stark based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Holger Stark. Holger Stark is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Živković, Aleksandra, et al.. (2025). Neuroinflammatory Human Brain Organoids Enable Comprehensive Drug Screening Studies: Fingolimod and its Analogues in Focus. Current Medicinal Chemistry. 33.

Nikolouli, Eirini, Susanne Mommert, Holger Stark, et al.. (2024). The stimulation of TH2 cells results in increased IL‐5 and IL‐13 production via the H₄ receptor. Allergy. 79(8). 2186–2196. 2 indexed citations

Godyń, Justyna, Marek Bajda, Tadeusz Karcz, et al.. (2024). 4-Oxypiperidine Ethers as Multiple Targeting Ligands at Histamine H₃ Receptors and Cholinesterases. ACS Chemical Neuroscience. 15(6). 1206–1218. 5 indexed citations

Al‐Soud, Yaseen A., Raed A. Al‐Qawasmeh, Najim A. Al‐Masoudi, et al.. (2024). Novel 4-nitroimidazole analogues: synthesis, in vitro biological evaluation, in silico studies, and molecular dynamics simulation. Zeitschrift für Naturforschung C. 79(3-4). 61–71.

Kutzsche, Janine, Antje Willuweit, Olaf Kletke, et al.. (2023). An orally available Ca_v2.2 calcium channel inhibitor for the treatment of neuropathic pain. British Journal of Pharmacology. 181(12). 1734–1756. 7 indexed citations

Olejarz‐Maciej, Agnieszka, Szczepan Mogilski, Tadeusz Karcz, et al.. (2023). Trisubstituted 1,3,5-Triazines as Histamine H4 Receptor Antagonists with Promising Activity In Vivo. Molecules. 28(10). 4199–4199. 2 indexed citations

Łażewska, Dorota, Paula Zaręba, Justyna Godyń, et al.. (2023). Multitargeting Histamine H3 Receptor Ligands among Acetyl- and Propionyl-Phenoxyalkyl Derivatives. Molecules. 28(5). 2349–2349. 4 indexed citations

Iwan, Magdalena, Marek Bajda, Justyna Godyń, et al.. (2023). Guanidines: Synthesis of Novel Histamine H3R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect. Pharmaceuticals. 16(5). 675–675. 4 indexed citations

Knez, Damijan, Izidor Sosič, Janez Mravljak, et al.. (2022). Repurposing of 8‐Hydroxyquinoline‐Based Butyrylcholinesterase and Cathepsin B Ligands as Potent Nonpeptidic Deoxyribonuclease I Inhibitors. ChemMedChem. 17(5). e202100694–e202100694. 6 indexed citations

10.

Niso, Mauro, Carmen Abate, Ewgenij Proschak, et al.. (2022). Design and Synthesis of Arylpiperazine Serotonergic/Dopaminergic Ligands with Neuroprotective Properties. Molecules. 27(4). 1297–1297. 4 indexed citations

11.

Jończyk, Jakub, Annika Frank, Holger Stark, et al.. (2021). Guanidine Derivatives: How Simple Structural Modification of Histamine H₃R Antagonists Has Led to the Discovery of Potent Muscarinic M₂R/M₄R Antagonists. ACS Chemical Neuroscience. 12(13). 2503–2519. 12 indexed citations

12.

Łażewska, Dorota, Agnieszka Olejarz‐Maciej, David Reiner‐Link, et al.. (2020). Dual Target Ligands with 4-tert-Butylphenoxy Scaffold as Histamine H3 Receptor Antagonists and Monoamine Oxidase B Inhibitors. International Journal of Molecular Sciences. 21(10). 3411–3411. 16 indexed citations

13.

Reiner‐Link, David, et al.. (2019). Profiling of LINS01 compounds at human dopamine D2 and D3 receptors. Journal of Chemical Sciences. 132(1). 7 indexed citations

14.

Hagenow, Stefanie, et al.. (2018). Novel indanone derivatives as MAO B/H3R dual-targeting ligands for treatment of Parkinson’s disease. European Journal of Medicinal Chemistry. 148. 487–497. 44 indexed citations

15.

Sander, Kerstin, Tim Kottke, Miriam Walter, et al.. (2010). First Metal-Containing Histamine H ₃ Receptor Ligands. Organic Letters. 12(11). 2578–2581. 16 indexed citations

16.

Gschwandtner, Maria, Kristine Roßbach, Dorothea Dijkstra, et al.. (2009). Murine and human Langerhans cells express a functional histamine H₄ receptor: modulation of cell migration and function. Allergy. 65(7). 840–849. 49 indexed citations

17.

Marcellino, Daniel, Sergi Ferré, Vicent Casadó, et al.. (2008). Identification of Dopamine D1–D3 Receptor Heteromers. Journal of Biological Chemistry. 283(38). 26016–26025. 193 indexed citations

18.

Gutzmer, Ralf, Susanne Mommert, Brigitta Köther, et al.. (2005). Histamine H4 Receptor Stimulation Suppresses IL-12p70 Production and Mediates Chemotaxis in Human Monocyte-Derived Dendritic Cells. The Journal of Immunology. 174(9). 5224–5232. 189 indexed citations

19.

Demphel, Stéphane, Chantal Fuseau, Michel Bottlaender, et al.. (1998). Radiosynthesis and biodistribution of two potential antagonists of cerebral histamine H3 receptors for PET studies: [18F]FUB 272 and [11C]UCL 1829. UCL Discovery (University College London). 2 indexed citations

20.

Scheich, Henning, et al.. (1995). Mapping of stimulus features and meaning in gerbil auditory cortex. Acta Neurobiologiae Experimentalis. 55(5). 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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