Steven D. Hughes

1.4k citations

22 papers · 1.1k indexed · h-index 16

Hepatology top 5%
Immunology top 10%
- Immune Cell Function and Interaction 6
- Immunotherapy and Immune Responses 6
- T-cell and B-cell Immunology 4
- Immunotoxicology and immune responses 2
Oncology top 10%
- CAR-T cell therapy research 3
Hematology
Surgery
- Pancreatic function and diabetes 5
Molecular Biology
- Metabolism, Diabetes, and Cancer 3
Cellular and Molecular Neuroscience
- Nuclear Receptors and Signaling 2

Co-authors: Matthew S. Holdren Thomas E. Palmer Debra G. Gilbertson Aaron C. Haran Edward M. Rubin Matthew M. Yeh Harald S. Haugen Renay L. Bauer
Cited by: Hepatology Immunology Oncology
Partner nations: United States Denmark China

In The Last Decade

Steven D. Hughes

22 papers receiving 1.1k citations

Peers

Countries citing papers authored by Steven D. Hughes

Since Specialization

Citations

This map shows the geographic impact of Steven D. Hughes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven D. Hughes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven D. Hughes more than expected).

Fields of papers citing papers by Steven D. Hughes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven D. Hughes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven D. Hughes. The network helps show where Steven D. Hughes may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Steven D. Hughes, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Steven D. Hughes Line = papers co-authored together Steven D. Hughes links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Preclinical Safety, Pharmacokinetics, and Pharmacodynamics of Recombinant Human Interleukin-21 in Cynomolgus Macaques (Macaca fascicularis) Kimberly S. Waggie,Matthew S. Holdren,Kelly Byrnes-Blake,Susan Pedersen,Rafael Ponce,Steven D. Hughes,Dennis M. Miller	2012	11
2	Clinical, Immunophenotypic, and Genetic Characterization of Small Lymphocyte–Like Plasma Cell Myeloma Amy Heerema‐McKenney,James Waldron,Steven D. Hughes,Fenghuang Zhan,Jeffery R. Sawyer,Bart Barlogie,John D. Shaughnessy	2010	22
3	Comparison of the ability of wild type and stabilized human IgG4 to undergo Fab arm exchange with endogenous IgG4 in vitro and in vivo Kenneth B. Lewis,Brent Meengs,Kent Bondensgaard,Lay Chin,Steven D. Hughes,B. Kjær,Søren Peter Lund,Liping Wang	2009	25
4	Topical recombinant thrombin at a concentration of 1000 IU/mL reliably shortens in vivo TTH and delivers durable hemostasis in the presence of heparin anticoagulation and clopidogrel platelet inhibition in a rabbit model of vascular bleeding Steven D. Hughes,Paul D. Bishop,Richard García,Tracy Zhang,W. Allan Alexander	2009	11
5	IL-21 induces in vivo immune activation of NK cells and CD8+ T cells in patients with metastatic melanoma and renal cell carcinoma Klaus Stensgaard Frederiksen,Dorthe Lundsgaard,Jeremy A. Freeman,Steven D. Hughes,Thomas Lindebo Holm,Birte K. Skrumsager,Andreas Petri,Lasse Tengbjerg Hansen,Grant A. McArthur,Ian D. Davis,Kresten Skak	2008	85
6	Immune activation in advanced cancer patients treated with recombinant IL-21: multianalyte profiling of serum proteins Michael Dodds,Klaus Stensgaard Frederiksen,Kresten Skak,Lasse Tengbjerg Hansen,Dorthe Lundsgaard,John A. Thompson,Steven D. Hughes	2008	21
7	Interleukin-21 Augments the Efficacy of T-Cell Therapy by Eliciting Concurrent Cellular and Humoral Responses Takekazu Iuchi,Seagal Teitz‐Tennenbaum,Jianhua Huang,Bruce G. Redman,Steven D. Hughes,Mu Li,Guihua Jiang,Alfred E. Chang,Qiao Li	2008	23
8	Phase I Study of Recombinant Interleukin-21 in Patients With Metastatic Melanoma and Renal Cell Carcinoma John A. Thompson,Brendan D. Curti,Bruce G. Redman,Shailender Bhatia,Jeffrey S. Weber,Sanjiv S. Agarwala,Eric L. Sievers,Steven D. Hughes,Todd DeVries,Diana F. Hausman	2008	149
9	Toxicity as a result of immunostimulation by biologics Elizabeth J Gribble,Pallavar V Sivakumar,Rafael Ponce,Steven D. Hughes	2007	29
10	IL-21 Enhances Tumor Rejection through a NKG2D-Dependent Mechanism Rayna Takaki,Yoshihiro Hayakawa,Andrew Nelson,Pallavur V. Sivakumar,Steven D. Hughes,Mark J. Smyth,Lewis L. Lanier	2005	105
11	Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma Jean S. Campbell,Steven D. Hughes,Debra G. Gilbertson,Thomas E. Palmer,Matthew S. Holdren,Aaron C. Haran,Melissa M. Odell,Renay L. Bauer,Hong-Ping Ren,Harald S. Haugen,Matthew M. Yeh,Nelson Fausto	2005	272
12	IL-21 Improves Rituximab-Mediated B Cell Depletion. Steven D. Hughes,Rafael Ponce,Cecile M. Krejsa,Werner Frings,Stephanie Bartsch,Julie P. Hill,Mark Rogge	2005	4
13	Exogenous PDGF-D Is a Potent Mesangial Cell Mitogen and Causes a Severe Mesangial Proliferative Glomerulopathy Kelly L. Hudkins,Debra G. Gilbertson,Matthew D. Carling,Sekiko Taneda,Steven D. Hughes,Matthew S. Holdren,Thomas E. Palmer,Stavros Topouzis,Aaron C. Haran,Andrew L. Feldhaus,Charles E. Alpers	2004	52
14	Apolipoprotein(a) Yeast Artificial Chromosome Transgenic Rabbits Didier Rouy,Nicolas Duverger,Sluan D. Lin,Florence Emmanuel,Louis‐Marie Houdebine,Patrice Denèfle,Céline Viglietta,Elaine L. Gong,Edward M. Rubin,Steven D. Hughes	1998	37
15	Vascular accumulation of Lp(a): in vivo analysis of the role of lysine‐binding sites using recombinant adenovirus Steven D. Hughes,Edward M. Rubin	1997	2
16	Gene Transfer of Cytidine Deaminase apoBEC-1 Lowers Lipoprotein(a) in Transgenic Mice and Induces Apolipoprotein B Editing in Rabbits Steven D. Hughes,Didier Rouy,Naveenan Navaratnam,James Scott,Edward M. Rubin	1996	37
17	Expression ofreg/PSP, a Pancreatic Exocrine Gene: Relationship to Changes in Islet β-Cell Mass Chisato Miyaura,Ling Chen,Michael Appel,Tausif Alam,Lindsey Inman,Steven D. Hughes,Joseph L. Milburn,Roger H. Unger,Christopher B. Newgard	1991	67
18	Analysis of the protein products encoded by variant glucokinase transcripts via expression in bacteria C Quaade,Steven D. Hughes,Ward Coats,Andrea L. Sestak,Patrick B. Iynedjian,Christopher B. Newgard	1991	13
19	Developmental expression of glycogenolytic enzymes in rabbit tissues: possible relationship to fetal lung maturation Christopher B. Newgard,Brian Norkiewicz,Steven D. Hughes,René Frenkel,Ward Coats,Frank Martiniuk,John M. Johnston	1991	10
20	Glucokinase and glucose transporter expression in liver and islets: implications for control of glucose homoeostasis Christopher B. Newgard,C Quaade,Steven D. Hughes,Joseph L. Milburn	1990	41

About Steven D. Hughes

Steven D. Hughes is a scholar working on Immunology, Oncology and Hematology, having authored 22 papers that have together received 1.1k indexed citations. Recurring topics across this work include Immune Cell Function and Interaction (6 papers), Immunotherapy and Immune Responses (6 papers), Pancreatic function and diabetes (5 papers), T-cell and B-cell Immunology (4 papers), CAR-T cell therapy research (3 papers), Metabolism, Diabetes, and Cancer (3 papers), Immunotoxicology and immune responses (2 papers) and Nuclear Receptors and Signaling (2 papers). The work is most often cited by research in Hepatology (162 citations), Immunology (425 citations) and Oncology (341 citations). Steven D. Hughes has collaborated with scholars based in United States, Denmark and China. Frequent co-authors include Matthew S. Holdren, Thomas E. Palmer, Debra G. Gilbertson, Aaron C. Haran, Edward M. Rubin, Matthew M. Yeh, Harald S. Haugen, Renay L. Bauer, Nelson Fausto and Jean S. Campbell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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