Steven D. Hughes

1.4k citations

22 papers · 1.1k indexed · h-index 16

Co-authors: Matthew S. Holdren Thomas E. Palmer Debra G. Gilbertson Aaron C. Haran Edward M. Rubin Matthew M. Yeh Harald S. Haugen Renay L. Bauer
Topics: Immune Cell Function and Interaction (6 papers)Immunotherapy and Immune Responses (6 papers)Pancreatic function and diabetes (5 papers)
Cited by: Hepatology Immunology Oncology
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry Journal of Clinical Oncology
Partner nations: United States Denmark China

In The Last Decade

Steven D. Hughes

22 papers receiving 1.1k citations

Peers

Countries citing papers authored by Steven D. Hughes

Since Specialization

Citations

This map shows the geographic impact of Steven D. Hughes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven D. Hughes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven D. Hughes more than expected).

Fields of papers citing papers by Steven D. Hughes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven D. Hughes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven D. Hughes. The network helps show where Steven D. Hughes may publish in the future.

Co-authorship network of co-authors of Steven D. Hughes

This figure shows the co-authorship network connecting the top 25 collaborators of Steven D. Hughes. A scholar is included among the top collaborators of Steven D. Hughes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Steven D. Hughes. Steven D. Hughes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Preclinical Safety, Pharmacokinetics, and Pharmacodynamics of Recombinant Human Interleukin-21 in Cynomolgus Macaques (Macaca fascicularis) 2012 ·International Journal of Toxicology ·Kimberly S. Waggie,Matthew S. Holdren,Kelly Byrnes-Blake,Susan Pedersen,Rafael Ponce,Steven D. Hughes,Dennis M. Miller	11
2	Clinical, Immunophenotypic, and Genetic Characterization of Small Lymphocyte–Like Plasma Cell Myeloma 2010 ·American Journal of Clinical Pathology ·Amy Heerema‐McKenney,(unknown),Steven D. Hughes,Fenghuang Zhan,Jeffery R. Sawyer,Bart Barlogie,John D. Shaughnessy	22
3	Comparison of the ability of wild type and stabilized human IgG4 to undergo Fab arm exchange with endogenous IgG4 in vitro and in vivo 2009 ·Molecular Immunology ·Kenneth B. Lewis,Brent Meengs,Kent Bondensgaard,(unknown),Steven D. Hughes,(unknown),Søren Peter Lund,Liping Wang	25
4	Topical recombinant thrombin at a concentration of 1000 IU/mL reliably shortens in vivo TTH and delivers durable hemostasis in the presence of heparin anticoagulation and clopidogrel platelet inhibition in a rabbit model of vascular bleeding 2009 ·PubMed ·Steven D. Hughes,Paul D. Bishop,Richard García,Tracy Zhang,(unknown)	11
5	IL-21 induces in vivo immune activation of NK cells and CD8+ T cells in patients with metastatic melanoma and renal cell carcinoma 2008 ·Cancer Immunology Immunotherapy ·Klaus Stensgaard Frederiksen,Dorthe Lundsgaard,Jeremy A. Freeman,Steven D. Hughes,Thomas Lindebo Holm,Birte K. Skrumsager,Andreas Petri,Lasse Tengbjerg Hansen,Grant A. McArthur,Ian D. Davis,Kresten Skak	85
6	Immune activation in advanced cancer patients treated with recombinant IL-21: multianalyte profiling of serum proteins 2008 ·Cancer Immunology Immunotherapy ·Michael Dodds,Klaus Stensgaard Frederiksen,Kresten Skak,Lasse Tengbjerg Hansen,Dorthe Lundsgaard,John A. Thompson,Steven D. Hughes	21
7	Interleukin-21 Augments the Efficacy of T-Cell Therapy by Eliciting Concurrent Cellular and Humoral Responses 2008 ·Cancer Research ·(unknown),Seagal Teitz‐Tennenbaum,Jianhua Huang,Bruce G. Redman,Steven D. Hughes,Mu Li,Guihua Jiang,Alfred E. Chang,Qiao Li	23
8	Phase I Study of Recombinant Interleukin-21 in Patients With Metastatic Melanoma and Renal Cell Carcinoma 2008 ·Journal of Clinical Oncology ·John A. Thompson,Brendan D. Curti,Bruce G. Redman,Shailender Bhatia,Jeffrey S. Weber,Sanjiv S. Agarwala,Eric L. Sievers,Steven D. Hughes,Todd DeVries,Diana F. Hausman	149
9	Toxicity as a result of immunostimulation by biologics 2007 ·Expert Opinion on Drug Metabolism & Toxicology ·(unknown),(unknown),Rafael Ponce,Steven D. Hughes	29
10	IL-21 Enhances Tumor Rejection through a NKG2D-Dependent Mechanism 2005 ·The Journal of Immunology ·Rayna Takaki,Yoshihiro Hayakawa,Andrew Nelson,Pallavur V. Sivakumar,Steven D. Hughes,Mark J. Smyth,Lewis L. Lanier	105
11	Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma 2005 ·Proceedings of the National Academy of Sciences ·Jean S. Campbell,Steven D. Hughes,Debra G. Gilbertson,Thomas E. Palmer,Matthew S. Holdren,Aaron C. Haran,(unknown),Renay L. Bauer,(unknown),Harald S. Haugen,Matthew M. Yeh,Nelson Fausto	272
12	IL-21 Improves Rituximab-Mediated B Cell Depletion. 2005 ·Blood ·Steven D. Hughes,Rafael Ponce,Cecile M. Krejsa,Werner Frings,(unknown),(unknown),Mark Rogge	4
13	Exogenous PDGF-D Is a Potent Mesangial Cell Mitogen and Causes a Severe Mesangial Proliferative Glomerulopathy 2004 ·Journal of the American Society of Nephrology ·Kelly L. Hudkins,Debra G. Gilbertson,Matthew D. Carling,Sekiko Taneda,Steven D. Hughes,Matthew S. Holdren,Thomas E. Palmer,Stavros Topouzis,Aaron C. Haran,Andrew L. Feldhaus,Charles E. Alpers	52
14	Apolipoprotein(a) Yeast Artificial Chromosome Transgenic Rabbits 1998 ·Journal of Biological Chemistry ·Didier Rouy,Nicolas Duverger,(unknown),Florence Emmanuel,Louis‐Marie Houdebine,Patrice Denèfle,Céline Viglietta,Elaine L. Gong,Edward M. Rubin,Steven D. Hughes	37
15	Vascular accumulation of Lp(a): in vivo analysis of the role of lysine‐binding sites using recombinant adenovirus 1997 ·Clinical Genetics ·Steven D. Hughes,Edward M. Rubin	2
16	Gene Transfer of Cytidine Deaminase apoBEC-1 Lowers Lipoprotein(a) in Transgenic Mice and Induces Apolipoprotein B Editing in Rabbits 1996 ·Human Gene Therapy ·Steven D. Hughes,Didier Rouy,Naveenan Navaratnam,James Scott,Edward M. Rubin	37
17	Expression ofreg/PSP, a Pancreatic Exocrine Gene: Relationship to Changes in Islet β-Cell Mass 1991 ·Molecular Endocrinology ·Chisato Miyaura,Ling Chen,Michael Appel,Tausif Alam,Lindsey Inman,Steven D. Hughes,Joseph L. Milburn,Roger H. Unger,Christopher B. Newgard	67
18	Analysis of the protein products encoded by variant glucokinase transcripts via expression in bacteria 1991 ·FEBS Letters ·C Quaade,Steven D. Hughes,Ward Coats,Andrea L. Sestak,Patrick B. Iynedjian,Christopher B. Newgard	13
19	Developmental expression of glycogenolytic enzymes in rabbit tissues: possible relationship to fetal lung maturation 1991 ·Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ·Christopher B. Newgard,(unknown),Steven D. Hughes,René Frenkel,Ward Coats,Frank Martiniuk,John M. Johnston	10
20	Glucokinase and glucose transporter expression in liver and islets: implications for control of glucose homoeostasis 1990 ·Biochemical Society Transactions ·Christopher B. Newgard,C Quaade,Steven D. Hughes,Joseph L. Milburn	41

About Steven D. Hughes

Steven D. Hughes is a scholar working on Immunology, Oncology and Hematology, having authored 22 papers that have together received 1.1k indexed citations. Recurring topics across this work include Immune Cell Function and Interaction (6 papers), Immunotherapy and Immune Responses (6 papers) and Pancreatic function and diabetes (5 papers). The work is most often cited by research in Hepatology (162 citations), Immunology (425 citations) and Oncology (341 citations). Steven D. Hughes has collaborated with scholars based in United States, Denmark and China. Frequent co-authors include Matthew S. Holdren, Thomas E. Palmer, Debra G. Gilbertson, Aaron C. Haran, Edward M. Rubin, Matthew M. Yeh, Harald S. Haugen, Renay L. Bauer, Nelson Fausto and Jean S. Campbell. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Oncology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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