Sophie Langouët

4.7k total citations · 1 hit paper
74 papers, 3.5k citations indexed

About

Sophie Langouët is a scholar working on Molecular Biology, Cancer Research and Pharmacology. According to data from OpenAlex, Sophie Langouët has authored 74 papers receiving a total of 3.5k indexed citations (citations by other indexed papers that have themselves been cited), including 40 papers in Molecular Biology, 22 papers in Cancer Research and 20 papers in Pharmacology. Recurrent topics in Sophie Langouët's work include Carcinogens and Genotoxicity Assessment (21 papers), Pharmacogenetics and Drug Metabolism (18 papers) and Genomics, phytochemicals, and oxidative stress (16 papers). Sophie Langouët is often cited by papers focused on Carcinogens and Genotoxicity Assessment (21 papers), Pharmacogenetics and Drug Metabolism (18 papers) and Genomics, phytochemicals, and oxidative stress (16 papers). Sophie Langouët collaborates with scholars based in France, United States and United Kingdom. Sophie Langouët's co-authors include André Guillouzo, F. Peter Guengerich, Fabrice Morel, A. Guillouzo, Robert J. Turesky, Georges Baffet, Christiane Guguen‐Guillouzo, Amélie Piton, Caroline Aninat and Denise Glaise and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Clinical Investigation and Biomaterials.

In The Last Decade

Sophie Langouët

73 papers receiving 3.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

EXPRESSION OF CYTOCHROMES P450, CONJUGATING ENZYMES AND NUCLEAR RECEPTORS IN HUMAN HEPATOMA HepaRG CELLS

2005 533 citations Caroline Aninat, Amélie Piton et al. Drug Metabolism and Disposition profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sophie Langouët France	32	1.8k	808	690	450	432	74	3.5k
Pablo Steinberg Germany	32	1.6k 0.9×	666 0.8×	374 0.5×	434 1.0×	427 1.0×	151	3.8k
Margaret M. Manson United Kingdom	46	3.7k 2.0×	893 1.1×	503 0.7×	811 1.8×	493 1.1×	109	6.3k
Fabrice Morel France	32	1.7k 0.9×	430 0.5×	1.2k 1.7×	683 1.5×	153 0.4×	51	3.6k
Seiko Tamano Japan	32	1.4k 0.8×	1.4k 1.7×	314 0.5×	540 1.2×	382 0.9×	144	3.8k
Nicola J. Hewitt Germany	28	600 0.3×	392 0.5×	822 1.2×	429 1.0×	329 0.8×	105	3.0k
Roger J. Price United Kingdom	30	815 0.4×	364 0.5×	1.3k 1.8×	558 1.2×	199 0.5×	95	2.6k
Hyung Gyun Kim South Korea	36	1.9k 1.0×	433 0.5×	590 0.9×	437 1.0×	309 0.7×	87	3.6k
Makoto Asamoto Japan	33	1.7k 0.9×	805 1.0×	266 0.4×	515 1.1×	345 0.8×	126	3.3k
Wolfram Parzefall Austria	27	988 0.5×	770 1.0×	254 0.4×	267 0.6×	408 0.9×	51	2.5k
Ming‐Shi Shiao Taiwan	42	2.5k 1.4×	737 0.9×	683 1.0×	172 0.4×	782 1.8×	111	5.6k

Countries citing papers authored by Sophie Langouët

Since Specialization

Citations

This map shows the geographic impact of Sophie Langouët's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sophie Langouët with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sophie Langouët more than expected).

Fields of papers citing papers by Sophie Langouët

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sophie Langouët. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sophie Langouët. The network helps show where Sophie Langouët may publish in the future.

Co-authorship network of co-authors of Sophie Langouët

This figure shows the co-authorship network connecting the top 25 collaborators of Sophie Langouët. A scholar is included among the top collaborators of Sophie Langouët based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sophie Langouët. Sophie Langouët is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Choi, Moonjung, Sophie Rose, & Sophie Langouët. (2025). Per- and polyfluoroalkyl substances as potentiators of hepatotoxicity in an exposome framework: Current challenges of environmental toxicology. Toxicology. 515. 154167–154167.

Rose, Sophie, Dominique Lagadic‐Gossmann, Xavier Coumoul, et al.. (2023). Assessment of endocrine disruptor impacts on lipid metabolism in a fatty acid-supplemented HepaRG human hepatic cell line. Chemosphere. 349. 140883–140883. 7 indexed citations

Rose, Sophie, et al.. (2023). Hepatotoxicity of cyanotoxin microcystin-LR in human: Insights into mechanisms of action in the 3D culture model Hepoid-HepaRG. Environmental Pollution. 342. 123047–123047. 13 indexed citations

Pathak, Khyatiben V., et al.. (2015). 2-Amino-9H-pyrido[2,3-b]indole (AαC) Adducts and Thiol Oxidation of Serum Albumin as Potential Biomarkers of Tobacco Smoke. Journal of Biological Chemistry. 290(26). 16304–16318. 18 indexed citations

Nizard, Philippe, Frédéric Ezan, Dominique Bonnier, et al.. (2014). Integrative analysis of high-throughput RNAi screen data identifies the FER and CRKL tyrosine kinases as new regulators of the mitogenic ERK-dependent pathways in transformed cells. BMC Genomics. 15(1). 1169–1169. 4 indexed citations

Guégan, Jean‐Philippe, Frédéric Ezan, Luc Gailhouste, Sophie Langouët, & Georges Baffet. (2013). MEK1/2 Overactivation Can Promote Growth Arrest by Mediating ERK1/2-Dependent Phosphorylation of p70S6K. Journal of Cellular Physiology. 229(7). 903–915. 18 indexed citations

Tang, Yijin, et al.. (2012). UDP-Glucuronosyltransferase-mediated Metabolic Activation of the Tobacco Carcinogen 2-Amino-9H-pyrido[2,3-b]indole. Journal of Biological Chemistry. 287(18). 14960–14972. 17 indexed citations

Bessette, Erin E., Dan Gu, Yijin Tang, et al.. (2011). DNA Adduct Formation of 4-Aminobiphenyl and Heterocyclic Aromatic Amines in Human Hepatocytes. Chemical Research in Toxicology. 24(6). 913–925. 66 indexed citations

Gu, Dachuan, et al.. (2011). Heterocyclic aromatic amines form high levels of DNA adducts in human hepatocytes. Toxicology Letters. 205. S38–S38. 1 indexed citations

10.

Langouët, Sophie, et al.. (2007). Differential toxic effects of azathioprine, 6-mercaptopurine and 6-thioguanine on human hepatocytes. Toxicology in Vitro. 22(3). 632–642. 65 indexed citations

11.

Aninat, Caroline, Amélie Piton, Denise Glaise, et al.. (2005). EXPRESSION OF CYTOCHROMES P450, CONJUGATING ENZYMES AND NUCLEAR RECEPTORS IN HUMAN HEPATOMA HepaRG CELLS. Drug Metabolism and Disposition. 34(1). 75–83. 533 indexed citations breakdown →

12.

Andrieux, Lise O., Sophie Langouët, Alain Fautrel, et al.. (2004). Aryl Hydrocarbon Receptor Activation and Cytochrome P450 1A Induction by the Mitogen-Activated Protein Kinase Inhibitor U0126 in Hepatocytes. Molecular Pharmacology. 65(4). 934–943. 67 indexed citations

13.

Turesky, Robert J., F. Peter Guengerich, André Guillouzo, & Sophie Langouët. (2002). Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2. Mutation research. Fundamental and molecular mechanisms of mutagenesis. 506-507. 187–195. 69 indexed citations

14.

Langouët, Sophie. (2002). Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rat and human hepatocytes. Carcinogenesis. 23(1). 115–122. 50 indexed citations

15.

Payen, Léa, Arnaud Courtois, Sophie Langouët, André Guillouzo, & Olivier Fardel. (2001). Unaltered expression of multidrug resistance transporters in polycyclic aromatic hydrocarbon-resistant rat liver cells. Toxicology. 156(2-3). 109–117. 14 indexed citations

16.

Langouët, Sophie, et al.. (2000). Inhibition of Human Cytochrome P450 Enzymes by 1,2-Dithiole-3-thione, Oltipraz and Its Derivatives, and Sulforaphane. Chemical Research in Toxicology. 13(4). 245–252. 94 indexed citations

17.

Mahéo, Karine, Fabrice Morel, Jocelyne Antras‐Ferry, et al.. (1998). Endotoxin Suppresses the Oltipraz–Mediated Induction of Major Hepatic Glutathione Transferases and Cytochromes P450 in the Rat. Hepatology. 28(6). 1655–1662. 25 indexed citations

18.

Ilyin, Gennady P., Sophie Langouët, Maryvonne Rissel, et al.. (1998). Ribavirin inhibits protein synthesis and cell proliferation induced by mitogenic factors in primary human and rat hepatocytes. Hepatology. 27(6). 1687–1694. 23 indexed citations

19.

Guillouzo, André, Fabrice Morel, Sophie Langouët, Karine Mahéo, & Maryvonne Rissel. (1997). Use of hepatocyte cultures for the study of hepatotoxic compounds. Journal of Hepatology. 26. 73–80. 56 indexed citations

20.

Mahéo, Karine, Jocelyne Antras‐Ferry, Fabrice Morel, Sophie Langouët, & André Guillouzo. (1997). Modulation of Glutathione S-Transferase Subunits A2, M1, and P1 Expression by Interleukin-1β in Rat Hepatocytes in Primary Culture. Journal of Biological Chemistry. 272(26). 16125–16132. 31 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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