Sofie Lautrup

5.9k total citations · 5 hit papers
25 papers, 3.7k citations indexed

About

Sofie Lautrup is a scholar working on Molecular Biology, Physiology and Geriatrics and Gerontology. According to data from OpenAlex, Sofie Lautrup has authored 25 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Molecular Biology, 10 papers in Physiology and 7 papers in Geriatrics and Gerontology. Recurrent topics in Sofie Lautrup's work include Sirtuins and Resveratrol in Medicine (7 papers), Autophagy in Disease and Therapy (7 papers) and DNA Repair Mechanisms (5 papers). Sofie Lautrup is often cited by papers focused on Sirtuins and Resveratrol in Medicine (7 papers), Autophagy in Disease and Therapy (7 papers) and DNA Repair Mechanisms (5 papers). Sofie Lautrup collaborates with scholars based in Norway, Denmark and United States. Sofie Lautrup's co-authors include Evandro Fei Fang, Mark P. Mattson, Vilhelm A. Bohr, Yujun Hou, Deborah L. Croteau, David Sinclair, Konstantinos Palikaras, Nektarios Tavernarakis, Hilde Nilsen and Beimeng Yang and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nature Communications and Nature Neuroscience.

In The Last Decade

Sofie Lautrup

23 papers receiving 3.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

2019 1.3k citations Evandro Fei Fang, Yujun Hou et al. profile →
NAD+ in Brain Aging and Neurodegenerative Disorders

2019 509 citations Sofie Lautrup, David Sinclair et al. Cell Metabolism profile →
NAD ⁺ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer’s disease via cGAS–STING

2021 367 citations Yujun Hou, Yong Wei et al. Proceedings of the National Academy of Sciences profile →
NAD ⁺ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

2018 340 citations Yujun Hou, Sofie Lautrup et al. Proceedings of the National Academy of Sciences profile →
Mitophagy and Neuroprotection

2019 333 citations Guofeng Lou, Konstantinos Palikaras et al. Trends in Molecular Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sofie Lautrup Norway	15	1.7k	1.3k	1.1k	608	562	25	3.7k
Valérie Vingtdeux United States	29	1.8k 1.1×	1.7k 1.3×	508 0.5×	372 0.6×	564 1.0×	47	4.2k
Yungui Zhou United States	22	1.5k 0.9×	2.2k 1.7×	483 0.4×	556 0.9×	1.3k 2.3×	29	4.3k
Beimeng Yang China	11	975 0.6×	765 0.6×	537 0.5×	165 0.3×	355 0.6×	18	2.1k
Charbel Moussa United States	36	1.5k 0.9×	1.6k 1.2×	793 0.7×	242 0.4×	704 1.3×	83	4.2k
Shaida A. Andrabi United States	28	3.1k 1.8×	792 0.6×	804 0.7×	298 0.5×	600 1.1×	45	5.5k
Bing Gong China	28	1.4k 0.8×	1.1k 0.8×	338 0.3×	243 0.4×	264 0.5×	52	3.0k
Ülkan Kılıç Türkiye	36	1.5k 0.9×	715 0.6×	345 0.3×	223 0.4×	979 1.7×	101	4.3k
Jieqiong Tan China	33	1.6k 1.0×	625 0.5×	1.1k 1.0×	109 0.2×	303 0.5×	131	3.6k
Tiina M. Kauppinen United States	28	1.5k 0.9×	680 0.5×	316 0.3×	197 0.3×	1.6k 2.8×	40	4.1k

Countries citing papers authored by Sofie Lautrup

Since Specialization

Citations

This map shows the geographic impact of Sofie Lautrup's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sofie Lautrup with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sofie Lautrup more than expected).

Fields of papers citing papers by Sofie Lautrup

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sofie Lautrup. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sofie Lautrup. The network helps show where Sofie Lautrup may publish in the future.

Co-authorship network of co-authors of Sofie Lautrup

This figure shows the co-authorship network connecting the top 25 collaborators of Sofie Lautrup. A scholar is included among the top collaborators of Sofie Lautrup based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sofie Lautrup. Sofie Lautrup is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Zhang, Shiqi, Zhangming Niu, Fang Shi, et al.. (2025). NR1D1 Inhibition Enhances Autophagy and Mitophagy in Alzheimer's Disease Models. Aging and Disease.

Laczó, Jan, Francesco Angelucci, Jakub Hort, et al.. (2025). Distinctive autophagy/mitophagy biomarker profiles in frontotemporal lobar degeneration and Alzheimer’s disease. Acta Neuropathologica Communications. 13(1). 37–37.

Wang, Heling, Jianying Zhang, Shuqin Cao, et al.. (2024). A luminescent-based protocol for NAD+/NADH detection in C. elegans, mice, and human whole blood. STAR Protocols. 5(4). 103428–103428. 2 indexed citations

Lautrup, Sofie, et al.. (2024). NAD+ Boosting Strategies. Sub-cellular biochemistry. 107. 63–90. 1 indexed citations

Lautrup, Sofie, et al.. (2024). WRN loss accelerates abnormal adipocyte metabolism in Werner syndrome. Cell & Bioscience. 14(1). 7–7. 5 indexed citations

Lautrup, Sofie, Yujun Hou, Evandro Fei Fang, & Vilhelm A. Bohr. (2023). Roles of NAD⁺in Health and Aging. Cold Spring Harbor Perspectives in Medicine. 14(1). a041193–a041193. 23 indexed citations

Pun, Frank W., Hoi-Wing Leung, Tomas Schmauck‐Medina, et al.. (2023). A comprehensive AI‐driven analysis of large‐scale omic datasets reveals novel dual‐purpose targets for the treatment of cancer and aging. Aging Cell. 22(12). e14017–e14017. 19 indexed citations

Lautrup, Sofie, Knud S. Larsen, Lisbeth S. Laursen, et al.. (2023). The role of aging and brain‐derived neurotrophic factor signaling in expression of base excision repair genes in the human brain. Aging Cell. 22(9). e13905–e13905. 8 indexed citations

Lautrup, Sofie, et al.. (2023). Phosphorylation of the Human DNA Glycosylase NEIL2 Is Affected by Oxidative Stress and Modulates Its Activity. Antioxidants. 12(2). 355–355. 4 indexed citations

10.

Lautrup, Sofie, Hui Zhao, Xiang Li, et al.. (2022). WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome. Nature Communications. 13(1). 5456–5456. 17 indexed citations

11.

Hou, Yujun, Yong Wei, Sofie Lautrup, et al.. (2021). NAD ⁺ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer’s disease via cGAS–STING. Proceedings of the National Academy of Sciences. 118(37). 367 indexed citations breakdown →

12.

Gilmour, Brian C., et al.. (2021). Crosstalk among DNA Damage, Mitochondrial Dysfunction, Impaired Mitophagy, Stem Cell Attrition, and Senescence in the Accelerated Ageing Disorder Werner Syndrome. Cytogenetic and Genome Research. 161(6-7). 297–304. 10 indexed citations

13.

Lautrup, Sofie, et al.. (2019). Microglial mitophagy mitigates neuroinflammation in Alzheimer's disease. Neurochemistry International. 129. 104469–104469. 80 indexed citations

14.

Lou, Guofeng, Konstantinos Palikaras, Sofie Lautrup, et al.. (2019). Mitophagy and Neuroprotection. Trends in Molecular Medicine. 26(1). 8–20. 333 indexed citations breakdown →

15.

Aman, Yahyah, Johannes Frank, Sofie Lautrup, et al.. (2019). The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications. Mechanisms of Ageing and Development. 185. 111194–111194. 40 indexed citations

16.

Lautrup, Sofie, Domenica Caponio, Hoi‐Hung Cheung, et al.. (2019). Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases. Biogerontology. 20(3). 255–269. 20 indexed citations

17.

Lautrup, Sofie, David Sinclair, Mark P. Mattson, & Evandro Fei Fang. (2019). NAD+ in Brain Aging and Neurodegenerative Disorders. Cell Metabolism. 30(4). 630–655. 509 indexed citations breakdown →

18.

Sánchez-Román, Inés, Sofie Lautrup, Maria D. Aamann, et al.. (2018). Two Cockayne Syndrome patients with a novel splice site mutation – clinical and metabolic analyses. Mechanisms of Ageing and Development. 175. 7–16. 5 indexed citations

19.

Fang, Evandro Fei, Sofie Lautrup, Yujun Hou, et al.. (2017). NAD + in Aging: Molecular Mechanisms and Translational Implications. Trends in Molecular Medicine. 23(10). 899–916. 361 indexed citations

20.

Fivenson, Elayne M., Sofie Lautrup, Nuo Sun, et al.. (2017). Mitophagy in neurodegeneration and aging. Neurochemistry International. 109. 202–209. 279 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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