Si Chen

2.6k citations

83 papers · 2.0k indexed · h-index 26

Impact in

Pharmaceutical Science top 5%
- Fluorine in Organic Chemistry
Cancer Research top 10%

Papers in ⓘ

Pharmacology 7
- Drug-Induced Hepatotoxicity and Protection 4
Biological Psychiatry 2

Co-authors: Yan Chen (13 shared papers)Lei Guo (9 shared papers)Yong‐Min Liang (7 shared papers)Ralph Weissleder (1 shared paper)Jiqiu Chen (1 shared paper)Jennifer R. Allport (1 shared paper)Ching‐Hsuan Tung (1 shared paper)Paul L. Huang (1 shared paper)
Journals: Circulation (5 papers)Archives of Toxicology (3 papers)Circulation Research (3 papers)Organic Letters (3 papers)Toxicological Sciences (3 papers)
Partner nations: China United States Brazil

In The Last Decade

Si Chen

80 papers receiving 2.0k citations

Peers

Countries citing papers authored by Si Chen

Since Specialization

Citations

This map shows the geographic impact of Si Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Si Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Si Chen more than expected).

Fields of papers citing papers by Si Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Si Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Si Chen. The network helps show where Si Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside Si Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Si Chen Line = papers co-authored together Si Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 83 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Near-Infrared Fluorescent Imaging of Matrix Metalloproteinase Activity After Myocardial Infarction Circulation ·Jiqiu Chen, Ching‐Hsuan Tung, Jennifer R. Allport, Si Chen, Ralph Weissleder, Paul L. Huang	2005	176
2	CD44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma Biomaterials ·Lina Wang, Weijun Su, Ze Liu, Manqian Zhou, Si Chen, Yanan Chen, Dan Lü, Yanhua Liu, Yan Fan, Yizhou Zheng, Zhongchao Han, Deling Kong, Joseph C. Wu, Rong Xiang, Zongjin Li	2012	164
3	AgSCF₃-Mediated Oxidative Trifluoromethythiolation of Alkynes with Dearomatization to Synthesize SCF₃-Substituted Spiro[4,5]trienones Organic Letters ·Dong‐Po Jin, Pin Gao, Dao-Qian Chen, Si Chen, Jia Wang, Xue‐Yuan Liu, Yong‐Min Liang	2016	118
4	Palladium-Catalyzed Intramolecular Dearomatization of Indoles via Decarboxylative Alkynyl Termination Organic Letters ·Si Chen, Xin‐Xing Wu, Jia Wang, Xin‐Hua Hao, Yu Xia, Yi Shen, Huanwang Jing, Yong‐Min Liang	2016	74
5	Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO‐1 Oxidative Medicine and Cellular Longevity ·Hai‐Han Liao, Jinxiu Zhu, Hong Feng, Jian Ni, Nan Zhang, Si Chen, Huang-Jun Liu, Zheng Yang, Wei Deng, Qizhu Tang	2017	71
6	PDE1C deficiency antagonizes pathological cardiac remodeling and dysfunction Proceedings of the National Academy of Sciences ·Walter E. Knight, Si Chen, Yishuai Zhang, Masayoshi Oikawa, Meiping Wu, Qian Zhou, Clint L. Miller, Yujun Cai, Deanne Mickelsen, Christine S. Moravec, Eric M. Small, Jun‐ichi Abe, Yan Chen	2016	69
7	A Novel Role of Cyclic Nucleotide Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction Circulation ·Si Chen, Yishuai Zhang, Janet K. Lighthouse, Deanne Mickelsen, Jiangbin Wu, Peng Yao, Eric M. Small, Yan Chen	2019	66
8	Activation of Notch1 signaling by marrow-derived mesenchymal stem cells through cell–cell contact inhibits proliferation of hepatic stellate cells Life Sciences ·Si Chen, Linan Xu, Nan Lin, Weidong Pan, Kunpeng Hu, Ruiyun Xu	2011	53
9	Endoplasmic Reticulum Stress in Drug- and Environmental Toxicant-Induced Liver Toxicity Journal of Environmental Science and Health Part C ·Si Chen, William B. Melchior, Lei Guo	2014	51
10	Inhibition of MEK blocks GRP78 up-regulation and enhances apoptosis induced by ER stress in gastric cancer cells Cancer Letters ·Lin‐Jie Zhang, Si Chen, Pin Wu, Chunsong Hu, Rick F. Thorne, Chang Luo, Peter Hersey, Xu Dong Zhang	2008	50
11	Myricetin Alleviates Pathological Cardiac Hypertrophy via TRAF6/TAK1/MAPK and Nrf2 Signaling Pathway Oxidative Medicine and Cellular Longevity ·Hai‐Han Liao, Nan Zhang, Yanyan Meng, Hong Feng, Jingjing Yang, Wenjin Li, Si Chen, Hai‐Ming Wu, Wei Deng, Qizhu Tang	2019	50
12	Multiprotein Complex With TRPC (Transient Receptor Potential-Canonical) Channel, PDE1C (Phosphodiesterase 1C), and A2R (Adenosine A2 Receptor) Plays a Critical Role in Regulating Cardiomyocyte cAMP and Survival Circulation ·Yishuai Zhang, Walter E. Knight, Si Chen, Amy Mohan, Yan Chen	2018	44
13	Endoplasmic reticulum stress and MAPK signaling pathway activation underlie leflunomide-induced toxicity in HepG2 Cells Toxicology ·Zhen Ren, Si Chen, Tao Qing, Jiekun Xuan, Letha H. Couch, Dianke Yu, Baitang Ning, Leming Shi, Lei Guo	2017	43
14	Retinoic Acid Receptor α Mediates All-trans-retinoic Acid-induced Klf4 Gene Expression by Regulating Klf4 Promoter Activity in Vascular Smooth Muscle Cells Journal of Biological Chemistry ·Jianhong Shi, Bin Zheng, Si Chen, Guo-Yan Ma, Jin‐Kun Wen	2012	41
15	ROS generation and JNK activation contribute to 4-methoxy-TEMPO-induced cytotoxicity, autophagy, and DNA damage in HepG2 cells Archives of Toxicology ·Zhuhong Zhang, Zhen Ren, Si Chen, Xiaoqing Guo, Fang Liu, Lei Guo, Nan Mei	2017	41
16	NP603, a novel and potent inhibitor of FGFR1 tyrosine kinase, inhibits hepatic stellate cell proliferation and ameliorates hepatic fibrosis in rats American Journal of Physiology-Cell Physiology ·Nan Lin, Si Chen, Weidong Pan, Linan Xu, Kunpeng Hu, Ruiyun Xu	2011	40
17	MicroRNA-143 promotes cardiac ischemia-mediated mitochondrial impairment by the inhibition of protein kinase Cepsilon Basic Research in Cardiology ·Hong Hong, Ting Tao, Si Chen, Chaoqi Liang, Yue Qiu, Yuhong Zhou, Rong Zhang	2017	39
18	PDE10A Inactivation Prevents Doxorubicin-Induced Cardiotoxicity and Tumor Growth Circulation Research ·Si Chen, Jiawei Chen, Wenting Du, Deanne Mickelsen, Hangchuan Shi, Han Yu, S. Kumar, Yan Chen	2023	38
19	β-Carboline Alkaloids from the Seeds of Peganum harmala and Their Anti-HSV-2 Virus Activities Organic Letters ·Zhong‐Nan Wu, Neng‐Hua Chen, Qing Tang, Si Chen, Zhao‐Chun Zhan, Yubo Zhang, Guo‐Cai Wang, Yao-Lan Li, Wen‐Cai Ye	2020	37
20	Caffeic acid phenethyl ester attenuates pathological cardiac hypertrophy by regulation of MEK/ERK signaling pathway in vivo and vitro Life Sciences ·Jie Ren, Nan Zhang, Hai‐Han Liao, Si Chen, Ling Xu, Jing Li, Zheng Yang, Wei Deng, Qizhu Tang	2017	35

About Si Chen

Si Chen is a scholar working on Pharmacology, Biological Psychiatry, Pharmaceutical Science, Molecular Biology and Cell Biology, having authored 83 papers that have together received 2.0k indexed citations. Recurring topics across this work include Phosphodiesterase function and regulation (8 papers), Catalytic C–H Functionalization Methods (6 papers), Endoplasmic Reticulum Stress and Disease (5 papers), Catalytic Cross-Coupling Reactions (4 papers), Cardiac Fibrosis and Remodeling (4 papers), Heart Failure Treatment and Management (4 papers), Drug-Induced Hepatotoxicity and Protection (4 papers) and Peptidase Inhibition and Analysis (4 papers). The work is most often cited by research in Pharmaceutical Science (91 citations), Cancer Research (215 citations), Molecular Biology (952 citations), Cardiology and Cardiovascular Medicine (295 citations) and Organic Chemistry (344 citations). Si Chen has collaborated with scholars based in China, United States and Brazil. Frequent co-authors include Yan Chen, Lei Guo, Yong‐Min Liang, Ralph Weissleder, Jiqiu Chen, Jennifer R. Allport, Ching‐Hsuan Tung, Paul L. Huang, Xue‐Yuan Liu and Yishuai Zhang. Their work appears in journals such as Circulation, Archives of Toxicology, Circulation Research, Organic Letters and Toxicological Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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