Ralph A. DeFronzo

408 total papers · 51.3k total citations
284 papers, 38.5k citations indexed

About

Ralph A. DeFronzo is a scholar working on Endocrinology, Diabetes and Metabolism, Molecular Biology and Surgery. According to data from OpenAlex, Ralph A. DeFronzo has authored 284 papers receiving a total of 38.5k indexed citations (citations by other indexed papers that have themselves been cited), including 178 papers in Endocrinology, Diabetes and Metabolism, 133 papers in Molecular Biology and 86 papers in Surgery. Recurrent topics in Ralph A. DeFronzo's work include Metabolism, Diabetes, and Cancer (114 papers), Diabetes Treatment and Management (110 papers) and Pancreatic function and diabetes (73 papers). Ralph A. DeFronzo is often cited by papers focused on Metabolism, Diabetes, and Cancer (114 papers), Diabetes Treatment and Management (110 papers) and Pancreatic function and diabetes (73 papers). Ralph A. DeFronzo collaborates with scholars based in United States, Italy and Qatar. Ralph A. DeFronzo's co-authors include Masafumi Matsuda, Eleuterio Ferrannini, Muhammad Abdul‐Ghani, Lawrence J. Mandarino, Gerald I. Shulman, Muhammad Abdul-Ghani, Donald C. Simonson, Douglas J. Smith, Robert R. Henry and Edward J. Barrett and has published in prestigious journals such as New England Journal of Medicine, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Ralph A. DeFronzo

281 papers receiving 37.1k citations

Hit Papers

Insulin sensitivity indic... 1975 2026 1992 2009 1999 1991 1988 2007 1990 1000 2.0k 3.0k 4.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation benchmark for papers published in the same subfield and year, or reaches the top citation threshold in at least one of its specific research topics.

  1. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.
    1999 4.7k citations Masafumi Matsuda, Ralph A. DeFronzo Diabetes Care profile →
  2. Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease
    1991 3.7k citations Ralph A. DeFronzo, Eleuterio Ferrannini Diabetes Care profile →
  3. The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for NIDDM
    1988 2.0k citations Ralph A. DeFronzo Diabetes profile →
  4. Impaired Fasting Glucose and Impaired Glucose Tolerance
    2007 1.1k citations David M. Nathan, Mayer B. Davidson et al. Diabetes Care profile →
  5. Quantitation of Muscle Glycogen Synthesis in Normal Subjects and Subjects with Non-Insulin-Dependent Diabetes by13C Nuclear Magnetic Resonance Spectroscopy
    1990 989 citations Gerald I. Shulman, Douglas L. Rothman et al. New England Journal of Medicine profile →
  6. Pathogenesis of type 2 diabetes mellitus
    2004 951 citations Ralph A. DeFronzo Medical Clinics of North America profile →
  7. Effect of fatty acids on glucose production and utilization in man.
    1983 888 citations Eleuterio Ferrannini, Edward J. Barrett et al. Journal of Clinical Investigation profile →
  8. The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man.
    1975 869 citations Ralph A. DeFronzo, Colin R. Cooke et al. Journal of Clinical Investigation profile →
  9. Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats.
    1987 684 citations Luciano Rossetti, Douglas J. Smith et al. Journal of Clinical Investigation profile →
  10. Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance.
    1989 662 citations Per‐Henrik Groop, Riccardo C. Bonadonna et al. Journal of Clinical Investigation profile →
  11. Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009
    2010 647 citations Ralph A. DeFronzo Diabetologia profile →
  12. Glucose Toxicity
    1990 643 citations Andrea Giaccari, Ralph A. DeFronzo et al. Diabetes Care profile →
  13. The effect of insulin on renal sodium metabolism
    1981 536 citations Ralph A. DeFronzo Diabetologia profile →
  14. Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance
    2008 534 citations Jacob M. Haus, Sangeeta R. Kashyap et al. Diabetes profile →
  15. Pioglitazone for Diabetes Prevention in Impaired Glucose Tolerance
    2011 525 citations Ralph A. DeFronzo, Devjit Tripathy et al. New England Journal of Medicine profile →
  16. Insulin resistance in uremia.
    1981 457 citations Ralph A. DeFronzo, Anders Alvestrand et al. Journal of Clinical Investigation profile →
  17. Epinephrine-induced Insulin Resistance in Man
    1980 439 citations Ralph A. DeFronzo et al. Journal of Clinical Investigation profile →
  18. Metformin-associated lactic acidosis: Current perspectives on causes and risk
    2015 439 citations Ralph A. DeFronzo, G. Alexander Fleming et al. Metabolism profile →
  19. Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Comprehensive Type 2 Diabetes Management Algorithm – 2020 Executive Summary
    2020 407 citations Alan J. Garber, Yehuda Handelsman et al. Endocrine Practice profile →
  20. Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Comprehensive Type 2 Diabetes Management Algorithm – 2018 Executive Summary
    2018 377 citations Alan J. Garber, Martin J. Abrahamson et al. Endocrine Practice profile →
  21. Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Comprehensive type 2 Diabetes Management Algorithm – 2017 Executive Summary
    2017 326 citations Alan J. Garber, Martin J. Abrahamson et al. Endocrine Practice profile →
  22. Insulin Resistance and Atherosclerosis: Implications for Insulin-Sensitizing Agents
    2019 305 citations Antonino Di Pino, Ralph A. DeFronzo Endocrine Reviews profile →
  23. Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Comprehensive Type 2 Diabetes Management Algorithm – 2019 Executive Summary
    2019 225 citations Alan J. Garber, Martin J. Abrahamson et al. Endocrine Practice profile →
  24. Insulin: The master regulator of glucose metabolism
    2022 178 citations Luke Norton, Chris E. Shannon et al. Metabolism profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Ralph A. DeFronzo 19.4k 13.5k 11.9k 8.1k 6.9k 284 38.5k
Richard E. Pratley 16.7k 0.9× 8.7k 0.6× 10.1k 0.9× 6.5k 0.8× 8.1k 1.2× 397 35.7k
Steven E. Kahn 20.9k 1.1× 12.7k 0.9× 13.3k 1.1× 12.9k 1.6× 9.2k 1.3× 470 46.4k
Hannele Yki‐Järvinen 16.3k 0.8× 9.6k 0.7× 9.4k 0.8× 6.0k 0.7× 13.3k 1.9× 382 35.5k
Ralph A. DeFronzo 24.5k 1.3× 21.0k 1.6× 17.7k 1.5× 12.0k 1.5× 9.0k 1.3× 427 52.1k
Ele Ferrannini 29.1k 1.5× 15.2k 1.1× 11.8k 1.0× 13.3k 1.6× 8.1k 1.2× 534 51.3k
Antonio Ceriello 17.1k 0.9× 7.6k 0.6× 7.9k 0.7× 5.6k 0.7× 4.2k 0.6× 492 36.1k
Robert R. Henry 12.7k 0.7× 11.0k 0.8× 7.1k 0.6× 7.0k 0.9× 5.2k 0.8× 292 27.7k
Leif Groop 14.6k 0.8× 12.3k 0.9× 7.5k 0.6× 9.9k 1.2× 5.5k 0.8× 553 36.5k
Donald S. Fredrickson 16.1k 0.8× 6.8k 0.5× 6.9k 0.6× 12.4k 1.5× 5.6k 0.8× 143 40.7k
Matti Uusitupa 13.4k 0.7× 6.8k 0.5× 11.9k 1.0× 5.2k 0.6× 5.2k 0.8× 481 37.4k

Countries citing papers authored by Ralph A. DeFronzo

Since Specialization
Citations

This map shows the geographic impact of Ralph A. DeFronzo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ralph A. DeFronzo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ralph A. DeFronzo more than expected).

Fields of papers citing papers by Ralph A. DeFronzo

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ralph A. DeFronzo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ralph A. DeFronzo. The network helps show where Ralph A. DeFronzo may publish in the future.

Co-authorship network of co-authors of Ralph A. DeFronzo

This figure shows the co-authorship network connecting the top 25 collaborators of Ralph A. DeFronzo. A scholar is included among the top collaborators of Ralph A. DeFronzo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ralph A. DeFronzo. Ralph A. DeFronzo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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