Robert E. Kyne

1.3k citations

20 papers · 1.0k indexed · h-index 16

Impact in

Organic Chemistry top 2%
- Click Chemistry and Applications
- Catalytic C–H Functionalization Methods
- Asymmetric Synthesis and Catalysis
- Catalytic Cross-Coupling Reactions
- Sulfur-Based Synthesis Techniques
Pharmaceutical Science top 2%
- Fluorine in Organic Chemistry

Papers in

Organic Chemistry 18
- Click Chemistry and Applications 8
- Cyclopropane Reaction Mechanisms 3
- Carbohydrate Chemistry and Synthesis 3
- Catalytic Cross-Coupling Reactions 2
- Catalytic Alkyne Reactions 2
Biotechnology 3
- Marine Sponges and Natural Products 3

Co-authors: James P. Morken Andrew C. Flick Carolyn A. Leverett Kevin K.‐C. Liu Hong X. DingPing ZhangSarah J. Fink Timo V. Ovaska
Journals: Organic Letters (4 papers)Bioorganic & Medicinal Chemistry (3 papers)Journal of Medicinal Chemistry (2 papers)ACS Chemical Biology (2 papers)Journal of the American Chemical Society (1 paper)
Partner nations: United States China Switzerland

In The Last Decade

Robert E. Kyne

20 papers receiving 981 citations

Peers

Countries citing papers authored by Robert E. Kyne

Since Specialization

Citations

This map shows the geographic impact of Robert E. Kyne's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert E. Kyne with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert E. Kyne more than expected).

Fields of papers citing papers by Robert E. Kyne

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert E. Kyne. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert E. Kyne. The network helps show where Robert E. Kyne may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Robert E. Kyne, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Robert E. Kyne Line = papers co-authored together Robert E. Kyne links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Synthetic Approaches to the New Drugs Approved During 2015 Journal of Medicinal Chemistry ·Andrew C. Flick, Hong X. Ding, Carolyn A. Leverett, Robert E. Kyne, Kevin K.‐C. Liu, Sarah J. Fink, Christopher J. O’Donnell	2017	111
2	Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue ACS Chemical Biology ·Olugbeminiyi Fadeyi, Lise R. Hoth, Chulho Choi, Xidong Feng, Ariamala Gopalsamy, Erik C. Hett, Robert E. Kyne, Ralph P. Robinson, Lyn H. Jones	2017	107
3	Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA) Journal of Medicinal Chemistry ·Ariamala Gopalsamy, Arjun Narayanan, Shenping Liu, Mihir D. Parikh, Robert E. Kyne, Olugbeminiyi Fadeyi, Michael A. Tones, Jonathan J. Cherry, Joseph F. Nabhan, Gregory J. LaRosa, Donna N. Petersen, Carol A. Menard, Timothy L. Foley, Stephen Noell, Yong Ren, Paula M. Loria, А. П. Комиссаров, Haojing Rong, Lyn H. Jones	2017	14
4	Synthetic approaches to the 2014 new drugs Bioorganic & Medicinal Chemistry ·Andrew C. Flick, Hong X. Ding, Carolyn A. Leverett, Robert E. Kyne, Kevin K.‐C. Liu, Sarah J. Fink, Christopher J. O’Donnell	2016	71
5	Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis ChemBioChem ·Olugbeminiyi Fadeyi, Mihir D. Parikh, Yao Pei-li, Robert E. Kyne, Alexandria P. Taylor, Inish O’Doherty, Stephen E. Kaiser, Abdelsalam Abdelfadel, Sherry Niessen, Liben He, Scott L. Weinrich, John C. Kath, Lyn H. Jones, Ralph P. Robinson	2016	46
6	Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cells Organic & Biomolecular Chemistry ·Hua Xu, Ariamala Gopalsamy, Erik C. Hett, I Pachiadikis, Ann Aulabaugh, Robert E. Kyne, Betsy S. Pierce, Lyn H. Jones	2016	16
7	Selectivity Determination of a Small Molecule Chemical Probe Using Protein Microarray and Affinity Capture Techniques ACS Combinatorial Science ·Erik C. Hett, Robert E. Kyne, Ariamala Gopalsamy, Michael A. Tones, Hua Xu, Fatmagül Süzen, 吴泽锋, Lyn H. Jones	2016	7
8	A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS Molecular BioSystems ·Hua Xu, Erik C. Hett, Ariamala Gopalsamy, Mihir D. Parikh, Kieran F. Geoghegan, Robert E. Kyne, Carol A. Menard, Arjun Narayanan, Ralph P. Robinson, Douglas S. Johnson, Michael A. Tones, Lyn H. Jones	2015	9
9	Synthetic approaches to the 2013 new drugs Bioorganic & Medicinal Chemistry ·Hong X. Ding, Carolyn A. Leverett, Robert E. Kyne, Kevin K.‐C. Liu, Sarah J. Fink, Andrew C. Flick, Christopher J. O’Donnell	2015	63
10	Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes ACS Chemical Biology ·Erik C. Hett, Hua Xu, Kieran F. Geoghegan, Ariamala Gopalsamy, Robert E. Kyne, Carol A. Menard, Arjun Narayanan, Mihir D. Parikh, Shenping Liu, Lee R. Roberts, Ralph P. Robinson, Michael A. Tones, Lyn H. Jones	2015	161
11	Synthesis of Pyrazoles from 1,3-Diols via Hydrogen Transfer Catalysis Organic Letters ·Daniel C. Schmitt, Alexandria P. Taylor, Andrew C. Flick, Robert E. Kyne	2015	47
12	Synthetic approaches to the 2012 new drugs Bioorganic & Medicinal Chemistry ·Hong X. Ding, Carolyn A. Leverett, Robert E. Kyne, Kevin K.‐C. Liu, Subas M. Sakya, Andrew C. Flick, Christopher J. O’Donnell	2014	33
13	Catalytic Enantioselective Allyl–Allyl Cross-Coupling with a Borylated Allylboronate Organic Letters ·Gregory Soderberg, Robert E. Kyne, Laura A. Brozek, James P. Morken	2013	42
14	Enantioselective Construction of All-Carbon Quaternary Centers by Branch-Selective Pd-Catalyzed Allyl–Allyl Cross-Coupling Journal of the American Chemical Society ·Ping Zhang, Gregory Soderberg, Robert E. Kyne, James P. Morken	2011	154
15	Allylation of Nitrosobenzene with Pinacol Allylboronates. A Regioselective Complement to Peroxide Oxidation Organic Letters ·Robert E. Kyne, Michael C. Ryan, Laura T. Kliman, James P. Morken	2010	33
16	Intramolecular thermal allenyne [2+2] cycloadditions: facile construction of the 5–6–4 ring core of sterpurene Tetrahedron Letters ·Timo V. Ovaska, Robert E. Kyne	2007	32
17	Total Syntheses of (.+‐.)‐Frondosin C (I) and (.+‐.)‐8‐epi‐Frondosin C via a Tandem Anionic 5‐exo Dig Cyclization—Claisen Rearrangement Sequence. ChemInform ·Xin Li, Robert E. Kyne, Timo V. Ovaska	2007	1
18	Synthesis of Seven-Membered Carbocyclic Rings via a Microwave-Assisted Tandem Oxyanionic 5-exo dig Cyclization−Claisen Rearrangement Process The Journal of Organic Chemistry ·Xin Li, Robert E. Kyne, Timo V. Ovaska	2007	16
19	Total syntheses of (±)-frondosin C and (±)-8-epi-frondosin C via a tandem anionic 5-exo dig cyclization–Claisen rearrangement sequence Tetrahedron ·Xin Li, Robert E. Kyne, Timo V. Ovaska	2006	21
20	Progress toward the Total Synthesis of Frondosin C Organic Letters ·Xin Li, Robert E. Kyne, Timo V. Ovaska	2006	19

About Robert E. Kyne

Robert E. Kyne is a scholar working on Organic Chemistry, Biotechnology, Pharmaceutical Science, Genetics and Molecular Biology, having authored 20 papers that have together received 1.0k indexed citations. Recurring topics across this work include Click Chemistry and Applications (8 papers), Chemical Synthesis and Analysis (5 papers), Marine Sponges and Natural Products (3 papers), Cyclopropane Reaction Mechanisms (3 papers), Carbohydrate Chemistry and Synthesis (3 papers), Catalytic Cross-Coupling Reactions (2 papers), Microbial Natural Products and Biosynthesis (2 papers) and Catalytic Alkyne Reactions (2 papers). The work is most often cited by research in Organic Chemistry (821 citations), Pharmaceutical Science (163 citations), Inorganic Chemistry (119 citations), Molecular Biology (359 citations) and Biotechnology (31 citations). Robert E. Kyne has collaborated with scholars based in United States, China and Switzerland. Frequent co-authors include James P. Morken, Andrew C. Flick, Carolyn A. Leverett, Kevin K.‐C. Liu, Hong X. Ding, Ping Zhang, Sarah J. Fink, Timo V. Ovaska, Lyn H. Jones and Christopher J. O’Donnell. Their work appears in journals such as Organic Letters, Bioorganic & Medicinal Chemistry, Journal of Medicinal Chemistry, ACS Chemical Biology and Journal of the American Chemical Society.

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