Robert A. Kirken

5.4k total citations · 1 hit paper
111 papers, 4.5k citations indexed

About

Robert A. Kirken is a scholar working on Oncology, Immunology and Molecular Biology. According to data from OpenAlex, Robert A. Kirken has authored 111 papers receiving a total of 4.5k indexed citations (citations by other indexed papers that have themselves been cited), including 77 papers in Oncology, 49 papers in Immunology and 35 papers in Molecular Biology. Recurrent topics in Robert A. Kirken's work include Cytokine Signaling Pathways and Interactions (68 papers), Immune Cell Function and Interaction (21 papers) and T-cell and B-cell Immunology (15 papers). Robert A. Kirken is often cited by papers focused on Cytokine Signaling Pathways and Interactions (68 papers), Immune Cell Function and Interaction (21 papers) and T-cell and B-cell Immunology (15 papers). Robert A. Kirken collaborates with scholars based in United States, Italy and Canada. Robert A. Kirken's co-authors include William L. Farrar, Hallgeir Rui, Rebecca A. Erwin, Zsuzsanna Nagy, Maria Grazia Malabarba, Jeremy A. Ross, Stanislaw M. Stepkowski, John R. Ortaldo, Masaru Kawamura and O. M. Zack Howard and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Robert A. Kirken

108 papers receiving 4.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2

1994 517 citations Robert A. Kirken et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Robert A. Kirken United States	37	2.2k	1.8k	1.6k	566	438	111	4.5k
Tomohide Tatsumi Japan	46	1.6k 0.7×	2.9k 1.6×	2.2k 1.3×	793 1.4×	135 0.3×	185	6.9k
Fabrice Gouilleux France	42	3.9k 1.7×	2.3k 1.3×	2.6k 1.6×	1.1k 1.9×	446 1.0×	88	6.6k
Vincent Castronovo Belgium	49	1.6k 0.7×	1.6k 0.9×	4.2k 2.5×	995 1.8×	133 0.3×	117	6.7k
Yukihiro Nishio Japan	30	1.9k 0.8×	1.9k 1.0×	2.7k 1.7×	1.2k 2.2×	205 0.5×	60	6.3k
John J. Krolewski United States	32	1.9k 0.9×	1.4k 0.8×	1.7k 1.0×	721 1.3×	252 0.6×	83	3.6k
James G. Karras United States	33	2.6k 1.2×	1.9k 1.0×	2.5k 1.5×	945 1.7×	265 0.6×	57	5.6k
Rocco Savino Italy	35	2.1k 0.9×	1.0k 0.5×	2.4k 1.5×	525 0.9×	193 0.4×	83	5.1k
Kaoru Kiguchi United States	36	1.9k 0.8×	1.1k 0.6×	3.0k 1.8×	832 1.5×	117 0.3×	77	5.3k
Wolfgang Doppler Austria	38	1.6k 0.7×	987 0.5×	2.1k 1.3×	559 1.0×	96 0.2×	90	4.2k
Gregory Hollis United States	36	1.0k 0.5×	996 0.5×	2.7k 1.6×	369 0.7×	113 0.3×	101	5.1k

Countries citing papers authored by Robert A. Kirken

Since Specialization

Citations

This map shows the geographic impact of Robert A. Kirken's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert A. Kirken with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert A. Kirken more than expected).

Fields of papers citing papers by Robert A. Kirken

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert A. Kirken. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert A. Kirken. The network helps show where Robert A. Kirken may publish in the future.

Co-authorship network of co-authors of Robert A. Kirken

This figure shows the co-authorship network connecting the top 25 collaborators of Robert A. Kirken. A scholar is included among the top collaborators of Robert A. Kirken based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert A. Kirken. Robert A. Kirken is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Sun, Shengjie, et al.. (2023). JAK3 Y841 Autophosphorylation Is Critical for STAT5B Activation, Kinase Domain Stability and Dimer Formation. International Journal of Molecular Sciences. 24(15). 11928–11928. 7 indexed citations

Sun, Shengjie, et al.. (2023). Phosphorylation of Tyrosine 841 Plays a Significant Role in JAK3 Activation. Life. 13(4). 981–981. 5 indexed citations

Sun, Shengjie, et al.. (2023). Structural Analysis of Janus Tyrosine Kinase Variants in Hematological Malignancies: Implications for Drug Development and Opportunities for Novel Therapeutic Strategies. International Journal of Molecular Sciences. 24(19). 14573–14573. 3 indexed citations

Gutiérrez, Denisse A., Karla Morán-Santibañez, Jonathon E. Mohl, et al.. (2022). Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways. Cells. 11(2). 254–254. 11 indexed citations

Estrada, Armando, et al.. (2021). Phosphorylation of CrkL S114 induced by common gamma chain cytokines and T-cell receptor signal transduction. Scientific Reports. 11(1). 16951–16951. 2 indexed citations

Desidero, Teresa Di, Marian Manciu, Giacomo Allegrini, et al.. (2020). Pharmacodynamic biomarkers in metronomic chemotherapy: multiplex cytokine measurements in gastrointestinal cancer patients. Clinical and Experimental Medicine. 21(1). 149–159. 8 indexed citations

Xiao, Xiao, Shixuan Wang, Hua Gao, et al.. (2019). Bif-1 Interacts with Prohibitin-2 to Regulate Mitochondrial Inner Membrane during Cell Stress and Apoptosis. PMC. 1 indexed citations

Carcamo, Benjamin, et al.. (2019). Integration of a Personalized Molecular Targeted Therapy into the Multimodal Treatment of Refractory Childhood Embryonal Tumor with Multilayered Rosettes (ETMR). Case Reports in Oncology. 12(1). 211–217. 5 indexed citations

Fu, Guanglei, Sharma T. Sanjay, Wan Zhou, et al.. (2018). Exploration of Nanoparticle-Mediated Photothermal Effect of TMB-H₂O₂ Colorimetric System and Its Application in a Visual Quantitative Photothermal Immunoassay. Analytical Chemistry. 90(9). 5930–5937. 240 indexed citations

10.

Ross, Jeremy A., et al.. (2012). Analysis of Janus Tyrosine Kinase Phosphorylation and Activation. Methods in molecular biology. 967. 3–20. 6 indexed citations

11.

Tan, Shyh‐Han, Ayush Dagvadorj, Feng Shen, et al.. (2008). Transcription Factor Stat5 Synergizes with Androgen Receptor in Prostate Cancer Cells. Cancer Research. 68(1). 236–248. 88 indexed citations

12.

Nagy, Zsuzsanna, Hallgeir Rui, Stanislaw M. Stepkowski, James G. Karras, & Robert A. Kirken. (2006). A Preferential Role for STAT5, not Constitutively Active STAT3, in Promoting Survival of a Human Lymphoid Tumor. The Journal of Immunology. 177(8). 5032–5040. 20 indexed citations

13.

Zhang, Ye, Robert A. Kirken, Lucrezia Furian, et al.. (2006). Allograft Rejection Requires STAT5a/b-Regulated Antiapoptotic Activity in T Cells but Not B Cells. The Journal of Immunology. 176(1). 128–137. 10 indexed citations

14.

Stepkowski, Stanislaw M., Mouer Wang, Neelam Tejpal, et al.. (2005). The Mannich Base NC1153 Promotes Long-Term Allograft Survival and Spares the Recipient from Multiple Toxicities. The Journal of Immunology. 175(7). 4236–4246. 29 indexed citations

15.

Langer, Róbert, Mouer Wang, Stanislaw M. Stepkowski, et al.. (2004). Selectin Inhibitor Bimosiamose Prolongs Survival of Kidney Allografts by Reduction in Intragraft Production of Cytokines and Chemokines. Journal of the American Society of Nephrology. 15(11). 2893–2901. 25 indexed citations

16.

Behbod, Fariba, Rebecca Erwin-Cohen, Mouer Wang, et al.. (2001). Concomitant Inhibition of Janus Kinase 3 and Calcineurin-Dependent Signaling Pathways Synergistically Prolongs the Survival of Rat Heart Allografts. The Journal of Immunology. 166(6). 3724–3732. 51 indexed citations

17.

Kirken, Robert A., et al.. (2000). Functional Uncoupling of the Janus Kinase 3-Stat5 Pathway in Malignant Growth of Human T Cell Leukemia Virus Type 1-Transformed Human T Cells. The Journal of Immunology. 165(9). 5097–5104. 40 indexed citations

18.

Yang, Yu‐Chung, et al.. (2000). Involvement of the Ubiquitin-Proteasome Pathway in the Degradation of Nontyrosine Kinase-Type Cytokine Receptors of IL-9, IL-2, and Erythropoietin. The Journal of Immunology. 165(11). 6372–6380. 48 indexed citations

19.

Kirken, Robert A., Rebecca Erwin-Cohen, Fariba Behbod, et al.. (1999). TYRPHOSTIN AG490 BLOCKS ACTIVATION OF JAK3 AND REJECTION OF HEART ALLOGRAFTS IN RATS. Transplantation. 67(9). S570–S570. 1 indexed citations

20.

Pericle, Federica, Lígia A. Pinto, Stuart W. Hicks, et al.. (1998). Cutting Edge: HIV-1 Infection Induces a Selective Reduction in STAT5 Protein Expression. The Journal of Immunology. 160(1). 28–31. 46 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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