Randy Hecht

6.8k total citations · 2 hit papers
21 papers, 5.5k citations indexed

About

Randy Hecht is a scholar working on Molecular Biology, Biomedical Engineering and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Randy Hecht has authored 21 papers receiving a total of 5.5k indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 4 papers in Biomedical Engineering and 3 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Randy Hecht's work include Fibroblast Growth Factor Research (9 papers), Kruppel-like factors research (9 papers) and Epigenetics and DNA Methylation (8 papers). Randy Hecht is often cited by papers focused on Fibroblast Growth Factor Research (9 papers), Kruppel-like factors research (9 papers) and Epigenetics and DNA Methylation (8 papers). Randy Hecht collaborates with scholars based in United States and Germany. Randy Hecht's co-authors include Dwight Winters, Mary Ann Pelleymounter, Mary Jane Cullen, Mary Baker, Thomas C. Boone, Frank M. Collins, Jing Xu, Murielle M. Véniant, Richard Lindberg and Shanaka Stanislaus and has published in prestigious journals such as Science, Journal of Biological Chemistry and Journal of Molecular Biology.

In The Last Decade

Randy Hecht

21 papers receiving 5.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice

1995 3.4k citations Mary Ann Pelleymounter, Mary Jane Cullen et al. Science profile →
Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

2008 974 citations Jing Xu, Shanaka Stanislaus et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Randy Hecht United States	13	2.9k	2.0k	1.9k	1.8k	1.7k	21	5.5k
Marlene Dembski United States	10	3.0k 1.0×	2.1k 1.0×	1.7k 0.9×	2.0k 1.1×	1.8k 1.0×	11	5.5k
Xun Weng China	7	3.5k 1.2×	2.3k 1.2×	932 0.5×	2.3k 1.3×	1.9k 1.1×	12	5.3k
Connie Zhao United States	22	1.9k 0.7×	1.2k 0.6×	966 0.5×	1.1k 0.6×	1.1k 0.7×	28	4.2k
Dwight Winters United States	10	2.9k 1.0×	1.7k 0.9×	560 0.3×	1.8k 1.0×	1.4k 0.8×	18	3.8k
Riccarda Granata Italy	34	2.1k 0.7×	1.6k 0.8×	1.1k 0.6×	1.1k 0.6×	722 0.4×	104	4.5k
Per Bo Jensen Denmark	22	1.6k 0.5×	1.1k 0.6×	922 0.5×	827 0.5×	706 0.4×	32	3.3k
Grayson Richards Switzerland	11	2.4k 0.8×	1.3k 0.7×	554 0.3×	1.5k 0.8×	1.2k 0.7×	12	3.3k
Y Yoshimasa Japan	20	1.5k 0.5×	1.1k 0.5×	573 0.3×	819 0.4×	909 0.5×	34	2.6k
Giulia Baldini United States	26	937 0.3×	1.9k 0.9×	1.8k 0.9×	310 0.2×	2.2k 1.3×	51	4.8k
Piet De Vos France	13	1.5k 0.5×	1.1k 0.6×	543 0.3×	904 0.5×	946 0.6×	19	2.4k

Countries citing papers authored by Randy Hecht

Since Specialization

Citations

This map shows the geographic impact of Randy Hecht's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Randy Hecht with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Randy Hecht more than expected).

Fields of papers citing papers by Randy Hecht

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Randy Hecht. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Randy Hecht. The network helps show where Randy Hecht may publish in the future.

Co-authorship network of co-authors of Randy Hecht

This figure shows the co-authorship network connecting the top 25 collaborators of Randy Hecht. A scholar is included among the top collaborators of Randy Hecht based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Randy Hecht. Randy Hecht is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Stanislaus, Shanaka, Randy Hecht, Junming Yie, et al.. (2017). A Novel Fc-FGF21 With Improved Resistance to Proteolysis, Increased Affinity Toward β-Klotho, and Enhanced Efficacy in Mice and Cynomolgus Monkeys. Endocrinology. 158(5). 1314–1327. 81 indexed citations

Yie, Junming, Wei Wang, Liying Deng, et al.. (2012). Understanding the Physical Interactions in the FGF21/FGFR/β‐Klotho Complex: Structural Requirements and Implications in FGF21 Signaling. Chemical Biology & Drug Design. 79(4). 398–410. 75 indexed citations

Hutterer, Katariina M., Zhongqi Zhang, Mark L. Michaels, et al.. (2012). Targeted codon optimization improves translational fidelity for an Fc fusion protein. Biotechnology and Bioengineering. 109(11). 2770–2777. 12 indexed citations

Porat, Amir, Dwight Winters, Ling Cai, et al.. (2012). A NOVEL ANION-EXCHANGE RESIN SUITABLE FOR BOTH DISCOVERY RESEARCH AND CLINICAL MANUFACTURING PURPOSES. Preparative Biochemistry & Biotechnology. 42(4). 304–321. 4 indexed citations

Véniant, Murielle M., Renée Komorowski, Ping Chen, et al.. (2012). Long-Acting FGF21 Has Enhanced Efficacy in Diet-Induced Obese Mice and in Obese Rhesus Monkeys. Endocrinology. 153(9). 4192–4203. 124 indexed citations

Gupte, Jamila, Li Yang, Xinle Wu, et al.. (2011). The FGFR D3 Domain Determines Receptor Selectivity For Fibroblast Growth Factor 21. Journal of Molecular Biology. 408(3). 491–502. 13 indexed citations

Li, Xiaofan, Hongfei Ge, Jennifer Weiszmann, et al.. (2009). Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice. FEBS Letters. 583(19). 3230–3234. 87 indexed citations

Wu, Xinle, Hongfei Ge, Bryan D. Lemon, et al.. (2009). FGF19-induced Hepatocyte Proliferation Is Mediated through FGFR4 Activation. Journal of Biological Chemistry. 285(8). 5165–5170. 151 indexed citations

Xu, Jing, Shanaka Stanislaus, Narumol Chinookoswong, et al.. (2009). Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models—association with liver and adipose tissue effects. American Journal of Physiology-Endocrinology and Metabolism. 297(5). E1105–E1114. 289 indexed citations

10.

Yie, Junming, Randy Hecht, Jennitte Stevens, et al.. (2008). FGF21 N‐ and C‐termini play different roles in receptor interaction and activation. FEBS Letters. 583(1). 19–24. 119 indexed citations

11.

Wisniewska, M., Peter Goettig, K. Maskos, et al.. (2008). Structural Determinants of the ADAM Inhibition by TIMP-3: Crystal Structure of the TACE-N-TIMP-3 Complex. Journal of Molecular Biology. 381(5). 1307–1319. 79 indexed citations

12.

Hecht, Randy, et al.. (2006). The high throughput purification of Fc-fusion proteins. Process Biochemistry. 41(12). 2473–2476. 5 indexed citations

13.

Pelleymounter, Mary Ann, et al.. (1998). Efficacy of exogenous recombinant murine leptin in lean and obese 10- to 12-mo-old female CD-1 mice. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 275(4). R950–R959. 52 indexed citations

14.

Hecht, Randy, et al.. (1996). Preparative Electrofocusing for Industrial Applications. Preparative Biochemistry & Biotechnology. 26(3-4). 201–216. 4 indexed citations

15.

Rozwarski, Denise A., Kay Diederichs, Randy Hecht, T. Boone, & P. Andrew Karplus. (1996). Refined crystal structure and mutagenesis of human granulocyte-macrophage colony-stimulating factor. Proteins Structure Function and Bioinformatics. 26(3). 304–313. 49 indexed citations

16.

Pelleymounter, Mary Ann, Mary Jane Cullen, Mary Baker, et al.. (1995). Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice. Science. 269(5223). 540–543. 3401 indexed citations breakdown →

17.

Freeman, John J., et al.. (1991). Secondary structure of human interleuken-3. International Journal of Biochemistry. 23(3). 353–360. 5 indexed citations

18.

Hecht, Randy, et al.. (1989). Micropreparative Capillary Zone Electrophoresis of Recombinant Human Interleukin-3. Preparative Biochemistry. 19(4). 363–366. 5 indexed citations

19.

Hecht, Randy, et al.. (1989). Capillary Zone Electrophoresis Separation of Recombinant Human Interleukin-3 and Related Proteins. Preparative Biochemistry. 19(3). 201–207. 5 indexed citations

20.

Hecht, Randy, et al.. (1977). Studies on the inner mitochondrial membrane localization of proline dehydrogenase. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 462(1). 171–176. 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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