Ji‐Wang Chern

2.6k citations

116 papers · 2.2k indexed · h-index 26

Impact in

Organic Chemistry top 2%
- Quinazolinone synthesis and applications
- Synthesis and Biological Evaluation
- Synthesis and biological activity
- Catalytic C–H Functionalization Methods
Molecular Biology top 10%
- Cancer therapeutics and mechanisms
- Histone Deacetylase Inhibitors Research
- Biochemical and Molecular Research

Papers in

Organic Chemistry 64
- Quinazolinone synthesis and applications 31
- Synthesis and Biological Evaluation 26
- Synthesis and Characterization of Heterocyclic Compounds 18
- Synthesis and biological activity 13
Physiology 5

Co-authors: Steve R. Roffler Chao‐Wu Yu Chai‐Lin Kao Tian‐Lu Cheng Chien‐Shu Chen Ming‐Fang Wu Grace Shiahuy Chen Ling‐Wei Hsin
Journals: Journal of Medicinal Chemistry (10 papers)Tetrahedron Letters (5 papers)Archiv der Pharmazie (4 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Current Medicinal Chemistry (3 papers)
Partner nations: Taiwan United States China

In The Last Decade

Ji‐Wang Chern

111 papers receiving 2.1k citations

Peers

Countries citing papers authored by Ji‐Wang Chern

Since Specialization

Citations

This map shows the geographic impact of Ji‐Wang Chern's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ji‐Wang Chern with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ji‐Wang Chern more than expected).

Fields of papers citing papers by Ji‐Wang Chern

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ji‐Wang Chern. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ji‐Wang Chern. The network helps show where Ji‐Wang Chern may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Ji‐Wang Chern, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ji‐Wang Chern Line = papers co-authored together Ji‐Wang Chern links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Disrupted target binding with acryloyl group as potential Bcr-Abl/C-Src dual kinase inhibitor optimization strategies with maintained antitumor activity Bioorganic & Medicinal Chemistry Letters ·Ching‐Fuh Lin, Bucceri Am, Grace Shiahuy Chen, Ji‐Wang Chern, Chao‐Wu Yu	2025	0
2	A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin‐induced apoptosis in castration‐resistant prostate cancer The Prostate ·Kevin Muster Regulus Victor, Cathrine Chong, Luciana Varkulja, David H. Ketel, R. Ramasubramanian, I. Iglesias-Martín, Universitas Mahasaraswati Denpasar Fakultas Bahasa Asing, Philipp Schüßler, Jui‐Ling Hsu, She‐Hung Chan, Lih‐Ching Hsu, Ji‐Wang Chern, Chao‐Wu Yu, Jih‐Hwa Guh	2024	2
3	J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice European Journal of Pharmaceutical Sciences ·Santiago Cavengt, Min Shao, Chen Zhao, M. Garcia Kako Rodrigues, Haitao Li, Guozhen Cui, Xiaonan Liang, Chao‐Wu Yu, Qingqing Ye, Gao Cheng, Lijun Di, Ji‐Wang Chern, Hefeng Zhou, Simon Ming‐Yuen Lee	2024	1
4	Antagonizing pathological α-synuclein-mediated neurodegeneration by J24335 via the activation of immunoproteasome Toxicology and Applied Pharmacology ·Santiago Cavengt, Chao‐Wu Yu, Chen Zhao, Min Shao, M. Garcia Kako Rodrigues, Xiaonan Liang, Haitao Li, 純二森田, Qingqing Ye, Ji‐Wang Chern, Jiahong Lu, Hefeng Zhou, Simon Ming‐Yuen Lee	2023	2
5	Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity Bioorganic Chemistry ·S. P. Rathnayake, Yu‐Hsuan Li, Chao‐Wu Yu, T. Zhang, J.-M. Kerleau, Jui‐Ling Hsu, Ling‐Wei Hsin, Chen-Tsung Huang, Hsueh‐Fen Juan, Ji‐Wang Chern, Yi‐Sheng Cheng	2021	5
6	4-Substituted 2-amino-3,4-dihydroquinazolines with a 3-hairpin turn side chain as novel inhibitors of BACE-1 Bioorganic Chemistry ·雅夫中野, Judith Da Fano, Marco Dieci, Hoe-wook 정혜욱Chung, Chia‐Ron Yang, Grace Shiahuy Chen, Ji‐Wang Chern	2019	11
7	Ureas: Applications in Drug Design Current Medicinal Chemistry ·雅夫中野, 陈朝环, Stuart Craig, Ji‐Wang Chern	2016	63
8	Discovery of N‐Arylalkyl‐3‐hydroxy‐4‐oxo‐3,4‐dihydroquinazolin‐2‐carboxamide Derivatives as HCV NS5B Polymerase Inhibitors ChemMedChem ·Eila Seppänen, Grace Shiahuy Chen, J M Sniffen, Alicia M. Barnett, Wiliam Oliveira da Silva, Gatto Ma, Jung‐Hsin Lin, Fan‐Lu Kung, Chien‐Shu Chen, Chun‐Tang Chiou, Ji‐Wang Chern	2012	7
9	NS5B RNA Dependent RNA Polymerase Inhibitors: The Promising Approach to Treat Hepatitis C Virus Infections Current Medicinal Chemistry ·Eila Seppänen, Ji‐Wang Chern	2010	32
10	Downregulation of GSTπ expression by tryptanthrin contributing to sensitization of doxorubicin-resistant MCF-7 cells through c-jun NH2-terminal kinase-mediated apoptosis Anti-Cancer Drugs ·Daniel Sanabria, Tzer-Ming Chen, Ji‐Wang Chern, 陳義元, Yen‐Hui Chen	2009	58
11	Synthesis and Primary Cytotoxic Screening of Some 3- Sulfonamide Substituted Benzamido-benzimidazolones Iranian journal of pharmaceutical research ·Ghadamali Khodarahmi, Pei‐Yu Chen, Min Long, Ji‐Wang Chern	2005	3
12	The β-Carboline Analog Mana-Hox Causes Mitotic Aberration by Interacting with DNA Chemistry & Biology ·Aksel Kornesjö, Chien‐Shu Chen, Я. О. Дудар, Ji‐Wang Chern, Chi‐Hung Lin, Ya‐Ching Shen, Sheau Farn Yeh	2005	36
13	Conjugated Polyhydroxybenzene Derivatives Block Tumor Necrosis Factor-α–Mediated Nuclear Factor-κB Activation and Cyclooxygenase-2 Gene Transcription by Targeting IκB Kinase Activity Molecular Pharmacology ·Ching‐Chow Chen, J. C. BernÃ ̈de, Shu-Ting Chan, Ji‐Wang Chern	2001	9
14	Pharmacological characterization of EK112, a new combined angiotensin II and thromboxane A2 receptor antagonist General Pharmacology The Vascular System ·Tsong‐Long Hwang, Darini Rajasingham, Ji‐Wang Chern, Che‐Ming Teng	2000	2
15	Bystander killing of tumour cells by antibody-targeted enzymatic activation of a glucuronide prodrug British Journal of Cancer ·Tian‐Lu Cheng, Lucy Clemence Kiteve, G. Carroll, Ji‐Wang Chern, Ming‐Fang Wu, A.Merchante, Steve R. Roffler	1999	40
16	Portal hypertensive effects of combined terlipressin and DL-028, a synthetic ?₁adrenoceptor antagonist administration on anesthetized portal hypertensive rats Liver International ·Yi‐Tsau Huang, Yanlei Wang, Ji‐Wang Chern, L. Longeart, Chuang-Ye Hong	1999	3
17	Poly(ethylene glycol) modification of β-glucuronidase-antibody conjugates for solid-tumor therapy by targeted activation of glucuronide prodrugs Cancer Immunology Immunotherapy ·Tian‐Lu Cheng, Bing‐Mae Chen, 尹金铭, 康彦和田, Ji‐Wang Chern, Steve R. Roffler	1997	44
18	Antiarrhythmic effects of BN‐063, a newly synthesized adenosine A₁ agonist, on myocardial ischaemia in rats British Journal of Pharmacology ·Yen‐Mei Lee, Ji‐Wang Chern, Mao‐Hsiung Yen	1994	8
19	3-β-D-Ribofuranosyl-6,7-dihydro-9H-thiazolo[3,2-a]purin-9-one hydrate Acta Crystallographica Section C Crystal Structure Communications ·Yen‐Chywan Liaw, A. H. J. Wang, Lin Gao, Ji‐Wang Chern	1994	0
20	Unusual conformational flexibility in N¹‐substituted uncommon purine nucleosides Crystal structure of 1‐allyl‐isoguanosine and 1‐allyl‐xanthosine FEBS Letters ·Yen‐Chywan Liaw, Ji‐Wang Chern, Aoha Roohi Amin, Andrew H.‐J. Wang	1992	9

About Ji‐Wang Chern

Ji‐Wang Chern is a scholar working on Organic Chemistry, Physiology, Molecular Biology, Toxicology and Infectious Diseases, having authored 116 papers that have together received 2.2k indexed citations. Recurring topics across this work include Quinazolinone synthesis and applications (31 papers), Synthesis and Biological Evaluation (26 papers), Synthesis and Characterization of Heterocyclic Compounds (18 papers), HIV/AIDS drug development and treatment (14 papers), Phenothiazines and Benzothiazines Synthesis and Activities (14 papers), Synthesis and biological activity (13 papers), Biochemical and Molecular Research (11 papers) and Histone Deacetylase Inhibitors Research (9 papers). The work is most often cited by research in Organic Chemistry (1.1k citations), Molecular Biology (1.2k citations), Toxicology (56 citations), Physiology (54 citations) and Biotechnology (100 citations). Ji‐Wang Chern has collaborated with scholars based in Taiwan, United States and China. Frequent co-authors include Steve R. Roffler, Chao‐Wu Yu, Chai‐Lin Kao, Tian‐Lu Cheng, Chien‐Shu Chen, Ming‐Fang Wu, Grace Shiahuy Chen, Ling‐Wei Hsin, Bing‐Mae Chen and Mao‐Hsiung Yen. Their work appears in journals such as Journal of Medicinal Chemistry, Tetrahedron Letters, Archiv der Pharmazie, Bioorganic & Medicinal Chemistry Letters and Current Medicinal Chemistry.

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