Paul M. O’Neill

14.7k total citations · 4 hit papers
214 papers, 10.4k citations indexed

About

Paul M. O’Neill is a scholar working on Public Health, Environmental and Occupational Health, Organic Chemistry and Molecular Biology. According to data from OpenAlex, Paul M. O’Neill has authored 214 papers receiving a total of 10.4k indexed citations (citations by other indexed papers that have themselves been cited), including 106 papers in Public Health, Environmental and Occupational Health, 71 papers in Organic Chemistry and 64 papers in Molecular Biology. Recurrent topics in Paul M. O’Neill's work include Malaria Research and Control (102 papers), Computational Drug Discovery Methods (44 papers) and Synthesis and Catalytic Reactions (30 papers). Paul M. O’Neill is often cited by papers focused on Malaria Research and Control (102 papers), Computational Drug Discovery Methods (44 papers) and Synthesis and Catalytic Reactions (30 papers). Paul M. O’Neill collaborates with scholars based in United Kingdom, United States and Portugal. Paul M. O’Neill's co-authors include Stephen A. Ward, Gary H. Posner, Patrick G. Bray, Victoria Barton, Giancarlo A. Biagini, Neil R. Kitteringham, James L. Maggs, Shaun R. Hawley, Paul A. Stocks and K. Nandra and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Paul M. O’Neill

212 papers receiving 10.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Artemisinins target the SERCA of Plasmodium falciparum

2003 775 citations Paul M. O’Neill, Stephen A. Ward et al. profile →
Metabolism of Fluorine-Containing Drugs

2001 507 citations Neil R. Kitteringham, Paul M. O’Neill et al. profile →
The Molecular Mechanism of Action of Artemisinin—The Debate Continues

2010 444 citations Paul M. O’Neill, Victoria Barton et al. profile →
An XMM-Newton survey of broad iron lines in Seyfert galaxies

2007 357 citations Paul M. O’Neill et al. profile →

Peers

Countries citing papers authored by Paul M. O’Neill

Since Specialization

Citations

This map shows the geographic impact of Paul M. O’Neill's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul M. O’Neill with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul M. O’Neill more than expected).

Fields of papers citing papers by Paul M. O’Neill

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul M. O’Neill. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul M. O’Neill. The network helps show where Paul M. O’Neill may publish in the future.

Co-authorship network of co-authors of Paul M. O’Neill

This figure shows the co-authorship network connecting the top 25 collaborators of Paul M. O’Neill. A scholar is included among the top collaborators of Paul M. O’Neill based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Paul M. O’Neill. Paul M. O’Neill is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Potent Preorganized Pyrazolidine Cyclophilin D Inhibitors Prevent Mitochondrial and Organ Injury in a Mouse Pancreatitis Disease Model 2025 ·Journal of Medicinal Chemistry ·(unknown), (unknown), (unknown), Michael S. Rogers, Neil M. Kershaw, Thomas Zacharchenko, (unknown), (unknown), Rajarshi Mukherjee, David N. Criddle, Suet C. Leung, Heather Lee, (unknown), Konstantin V. Luzyanin, Neil G. Berry, S.V. Antonyuk, Lu‐Yun Lian, Robert Sutton, Paul M. O’Neill	0
2	Inhibition of PRC2 enables self-renewal of blastoid-competent naive pluripotent stem cells from chimpanzee 2025 ·Cell stem cell ·Tao Huang, (unknown), Ayaka Yanagida, (unknown), (unknown), (unknown), Dong-Wan Kim, Paul M. O’Neill, James S. Clarke, Madeline A. Lancaster, (unknown), (unknown), (unknown), Petra Hájková, Ferdinand von Meyenn, Hiroo Imai, Hiromitsu Nakauchi, Ge Guo, Austin Smith, Hideki Masaki	1
3	A Phase 1, Randomized, Double‐Blind, Placebo‐Controlled, Single Ascending Dose Trial of AWZ1066S, an Anti‐Wolbachia Candidate Macrofilaricide 2024 ·Clinical Pharmacology in Drug Development ·(unknown), Marcin Bula, (unknown), Richard J. Fitzgerald, (unknown), (unknown), Tomoyuki Moriyama, Raku Shinkyo, Lauren Walker, Duolao Wang, Fabian Gusovsky, (unknown), Joseph D. Turner, W. David Hong, Paul M. O’Neill, Mark J. Taylor, Stephen A. Ward	1
4	Novel antimalarial 3-substituted quinolones isosteres with improved pharmacokinetic properties 2024 ·European Journal of Medicinal Chemistry ·Si-Yuan Ge, (unknown), (unknown), (unknown), (unknown), Wenjiao Li, Xiaole Chen, Rui‐Kang Huang, Chi‐Sing Lee, Suet C. Leung, Nicoletta Basilico, Silvia Parapini, Donatella Taramelli, (unknown), S.V. Antonyuk, Paul M. O’Neill, Zhaojun Sheng, W. David Hong	1
5	Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform 2024 ·Frontiers in Pharmacology ·Laura-Oana Albulescu, Adam Westhorpe, Rachel H. Clare, (unknown), (unknown), Jeroen Kool, Neil G. Berry, Paul M. O’Neill, Nicholas R. Casewell	5
6	Convenient syntheses of 2-acylamino-4-halothiazoles and acylated derivatives using a versatile Boc-intermediate 2024 ·RSC Advances ·(unknown), (unknown), (unknown), Craig M. Robertson, Paul M. O’Neill, Andrew V. Stachulski	0
7	Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement 2024 ·Scientific Reports ·Seiji Watanabe, Kangsa Amporndanai, (unknown), (unknown), Muhammad Awais, Paul M. O’Neill, Koji Yamanaka, S.S. Hasnain	3
8	Dirofilariasis mouse models for heartworm preclinical research 2023 ·Frontiers in Microbiology ·(unknown), (unknown), (unknown), Andrew Steven, (unknown), (unknown), Abdelmoneim Mansour, Edward J. Campbell, Craig M. Wilson, Fabian Gusovsky, Stephen A. Ward, (unknown), Paul M. O’Neill, (unknown), (unknown), John W. McCall, Mark J. Taylor, Joseph D. Turner	7
9	Development of Pyrazolopyrimidine Anti-Wolbachia Agents for the Treatment of Filariasis 2021 ·ACS Medicinal Chemistry Letters ·(unknown), Neil G. Berry, Gemma L. Nixon, Suet C. Leung, Peter J. H. Webborn, Mark C. Wenlock, Stefan Kavanagh, Andrew Cassidy, Rachel H. Clare, Darren A. N. Cook, Kelly L. Johnston, Louise Ford, Stephen A. Ward, Mark J. Taylor, W. David Hong, Paul M. O’Neill	6
10	Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives 2021 ·Nature Communications ·Kangsa Amporndanai, Xiaoli Meng, Weijuan Shang, Zhenming Jin, Michael S. Rogers, Yao Zhao, Zihe Rao, Zhi‐Jie Liu, Haitao Yang, Leike Zhang, Paul M. O’Neill, S.S. Hasnain	178
11	Synthesis, insecticidal activities and resistance in Aedes albopictus and cytotoxicity of novel dihaloacetylated heterocyclic pyrethroids 2019 ·Pest Management Science ·Qiuyan Zhu, Yang Yang, (unknown), Yingying Zhong, Bingjie Zhang, Xiping Cui, Paul M. O’Neill, David W. Hong, Kun Zhang, Suqing Zhao	16
12	Control and regulation of S‐Adenosylmethionine biosynthesis by the regulatory β subunit and quinolone‐based compounds 2019 ·FEBS Journal ·(unknown), (unknown), José M. Mato, Paul M. O’Neill, S.V. Antonyuk, S.S. Hasnain	11
13	Antimalarial activity of primaquine operates via a two-step biochemical relay 2019 ·Nature Communications ·Grazia Camarda, (unknown), (unknown), Ahmed Saif, Sandra March, Michael H. L. Wong, Suet C. Leung, A. B. Miller, David A. Baker, Pietro Alano, Mark J. I. Paine, Sangeeta N. Bhatia, Paul M. O’Neill, Stephen A. Ward, Giancarlo A. Biagini	92
14	Phosphinic acids: current status and potential for drug discovery 2018 ·Drug Discovery Today ·Moaz M. Abdou, Paul M. O’Neill, Eric Amigues, Magdalini Matziari	43
15	Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7 2016 ·Proceedings of the National Academy of Sciences ·Hanafy M. Ismail, Victoria Barton, Matthew Phanchana, Sitthivut Charoensutthivarakul, Michael H. L. Wong, Janet Hemingway, Giancarlo A. Biagini, Paul M. O’Neill, Stephen A. Ward	188
16	Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney 2015 ·Kidney International ·Luke M. Shelton, Adam Lister, Joanne Walsh, Rosalind E. Jenkins, Michael H. L. Wong, Cliff Rowe, Emanuele Ricci, Lorenzo Ressel, Yongxiang Fang, Philippe Demougin, Vanja Vukojević, Paul M. O’Neill, Christopher E. Goldring, Neil R. Kitteringham, (unknown), Alex Odermatt, Ian M. Copple	44
17	Towards depersonalized abacavir therapy 2015 ·AIDS ·Dean J. Naisbitt, (unknown), (unknown), Neil G. Berry, Alexandre S. Lawrenson, John Farrell, Philip Martin, Klaus Strebel, Andrew Owen, (unknown), Neil French, Stephen E. Clarke, Paul M. O’Neill, (unknown)	13
18	A novel drug for uncomplicated malaria: Targeted high throughput screening (HTS) against the type II NADH:ubiquinone oxidoreductase (PfNDH2) of Plasmodium falciparum 2010 ·Biochimica et Biophysica Acta (BBA) - Bioenergetics ·Nicholas Fisher, (unknown), Alison Mbekeani, Alison E. Shone, Gemma L. Nixon, Paul A. Stocks, Peter Gibbons, Richard K. Amewu, W. David Hong, Victoria Barton, (unknown), James Chadwick, (unknown), Ashley J. Warman, Raman Sharma, Neil G. Berry, Paul M. O’Neill, Stephen A. Ward, Giancarlo A. Biagini	1
19	Piperidine dispiro-1,2,4-trioxane analogues 2008 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Paul A. Stocks, (unknown), Jill Davies, Erik Hedenström, Stephen A. Ward, Paul M. O’Neill	23
20	Antimalarial chemotherapy: young guns or back to the future? 2003 ·Trends in Parasitology ·Giancarlo A. Biagini, Paul M. O’Neill, Alexis Nzila, Stephen A. Ward, Patrick G. Bray	73

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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