James L. Maggs

5.7k citations

109 papers · 4.5k indexed · h-index 40

Impact in

Pharmacology top 0.1%
- Pharmacogenetics and Drug Metabolism
- Drug-Induced Hepatotoxicity and Protection
- Drug-Induced Adverse Reactions
Computational Theory and Mathematics top 1%
- Computational Drug Discovery Methods

Papers in

Pharmacology 55
- Pharmacogenetics and Drug Metabolism 46
- Drug-Induced Hepatotoxicity and Protection 18
- Drug-Induced Adverse Reactions 13
- Inflammatory mediators and NSAID effects 8
Biochemistry 10

Co-authors: Munir Pirmohamed Dominic P. Williams Paul M. O’Neill Dean J. Naisbitt B.K. Park Neil R. Kitteringham B. Kevin Park Andrew V. Stachulski
Journals: Chemical Research in Toxicology (14 papers)Biochemical Pharmacology (13 papers)Journal of Pharmacology and Experimental Therapeutics (11 papers)Journal of Medicinal Chemistry (10 papers)Xenobiotica (7 papers)
Partner nations: United Kingdom United States Australia

In The Last Decade

James L. Maggs

108 papers receiving 4.3k citations

Peers

Countries citing papers authored by James L. Maggs

Since Specialization

Citations

This map shows the geographic impact of James L. Maggs's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James L. Maggs with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James L. Maggs more than expected).

Fields of papers citing papers by James L. Maggs

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James L. Maggs. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James L. Maggs. The network helps show where James L. Maggs may publish in the future.

Co-authors

The 25 scholars most cited alongside James L. Maggs, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James L. Maggs Line = papers co-authored together James L. Maggs links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury Archives of Toxicology ·Ian M. Copple, Wouter den Hollander, Giulia Callegaro, Fiona Mutter, James L. Maggs, Amy Schofield, Lucille Rainbow, Yongxiang Fang, Jeffrey J. Sutherland, Ewa Ellis, Magnus Ingelman‐Sundberg, Stephen W. Fenwick, Christopher E. Goldring, Bob van de Water, James Stevens, B. Kevin Park	2018	22
2	Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from a Drug Acyl Glucuronide Metabolite: Multiple Albumin Adductions in Diclofenac Patients Journal of Pharmacology and Experimental Therapeutics ·Thomas Hammond, Xiaoli Meng, Rosalind E. Jenkins, James L. Maggs, Anahi Santoyo Castelazo, Sophie Regan, Stuart N. L. Bennett, Caroline J. Earnshaw, Guruprasad P. Aithal, Ira Pande, J. Gerry Kenna, Andrew V. Stachulski, B. Kevin Park, Dominic P. Williams	2014	50
3	Convenient syntheses of halo-dibenz[b,f]azepines and carbamazepine analogues via N-arylindoles Organic & Biomolecular Chemistry ·Emma‐Claire Elliott, James L. Maggs, B. Kevin Park, Paul M. O’Neill, Andrew V. Stachulski	2013	21
4	Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic Acid in Patients Journal of Pharmacology and Experimental Therapeutics ·Xiaoli Meng, Rosalind E. Jenkins, Neil G. Berry, James L. Maggs, John Farrell, Catherine Lane, Andrew V. Stachulski, Neil French, Dean J. Naisbitt, Munir Pirmohamed, B. Kevin Park	2011	72
5	Role of Reactive Metabolites in Drug-Induced Hepatotoxicity Handbook of experimental pharmacology ·Abhishek Srivastava, James L. Maggs, Daniel J. Antoine, Dominic P. Williams, Dennis A. Smith, B. K. Park	2009	121
6	Quantifying the Metabolic Activation of Nevirapine in Patients by Integrated Applications of NMR and Mass Spectrometries Drug Metabolism and Disposition ·Abhishek Srivastava, Lu‐Yun Lian, James L. Maggs, Masautso Chaponda, Munir Pirmohamed, Dominic P. Williams, B. Kevin Park	2009	46
7	Identification of the Thiophene Ring of Methapyrilene as a Novel Bioactivation-Dependent Hepatic Toxicophore Journal of Pharmacology and Experimental Therapeutics ·Emma E. Graham, Rachel J. Walsh, Charlotte Hirst, James L. Maggs, Scott Martin, Martin Wild, Ian D. Wilson, John Harding, J. Gerry Kenna, Raimund M. Peter, Dominic P. Williams, B. Kevin Park	2008	33
8	Nonenzymatic Formation of a Novel Hydroxylated Sulfamethoxazole Derivative in Human Liver Microsomes: Implications for Bioanalysis of Sulfamethoxazole Metabolites Drug Metabolism and Disposition ·Joseph P. Sanderson, F. J. Hollis, James L. Maggs, Stephen E. Clarke, Dean J. Naisbitt, B. Kevin Park	2008	6
9	Activation of Human Dendritic Cells by p-Phenylenediamine Journal of Pharmacology and Experimental Therapeutics ·Eve Coulter, John Farrell, Karen L Mathews, James L. Maggs, Camilla Pease, David Lockley, David A. Basketter, B. Kevin Park, Dean J. Naisbitt	2006	38
10	Glucuronidation of Dihydroartemisinin in Vivo and by Human Liver Microsomes and Expressed UDP-Glucuronosyltransferases Drug Metabolism and Disposition ·Kenneth F. Ilett, Brian Ethell, James L. Maggs, Timothy M. E. Davis, Kevin T. Batty, Brian Burchell, Trần Quang Bình, Le Thi Anh Thư, Nguyen Canh Hung, Munir Pirmohamed, B. Kevin Park, Geoffrey Edwards	2002	111
11	Comparison of the Modulatory Effects of Human and Rat Liver Microsomal Metabolism on the Estrogenicity of Bisphenol A: Implications for Extrapolation to Humans Journal of Pharmacology and Experimental Therapeutics ·Robert Elsby, James L. Maggs, John Ashby, B. Kevin Park	2001	91
12	Methapyrilene hepatotoxicity is associated with increased hepatic glutathione, the formation of glucuronide conjugates, and enterohepatic recirculation Chemico-Biological Interactions ·Gurpreet S. Ratra, Christopher J. Powell, B.Kevin Park, James L. Maggs, S. Cottrell	2000	22
13	α-Hydroxytamoxifen, a genotoxic metabolite of tamoxifen in the rat: identification and quantification in vivo and in vitro Carcinogenesis ·David J. Boocock, James L. Maggs, Ian N.H. White, B. Kevin Park	1999	42
14	The effect of 2,2′-substitution on the metabolism and toxicity of dapsone in vitro and in vivo Environmental Toxicology and Pharmacology ·Malcolm D. Tingle, Roziahanim Mahmud, James L. Maggs, Shaun R. Hawley, Michael D. Coleman, Stephen A. Ward, B.K Park	1998	4
15	In vitro metabolism of dexamethasone (DEX) in human liver and kidney: The involvement of CYP3a4 and CYP17 (17,20 LYASE) and molecular modelling studies Biochemical Pharmacology ·E.S. Tomlinson, D. F. V. Lewis, James L. Maggs, H K Kroemer, B.K. Park, D.J. Back	1997	48
16	The metabolism of 16-fluoroestradiols in vivo: Chemical strategies for restricting the oxidative biotransformations of an estrogen-receptor imaging agent Steroids ·Anne C. Stalford, James L. Maggs, T. L. Gilchrist, BK Park	1997	12
17	Oxidative dehalogenation of 2-fluoro-17α-ethynyloestradiol in vivo Biochemical Pharmacology ·Paul Morgan, James L. Maggs, Philip C. Bulman Page, B.K. Park	1992	13
18	The metabolism of 2- and 4-fluoro-17β- oestradiol in the rat and its implications for oestrogen carcinogenesis Biochemical Pharmacology ·Paul Morgan, James L. Maggs, Philip C. Bulman Page, Fazal Hussain, B.K. Park	1992	19
19	Cortisol metabolism by human liver in vitro—I. Metabolite identification and inter-individual variability The Journal of Steroid Biochemistry and Molecular Biology ·Steffen Abel, James L. Maggs, David Back, B.K. Park	1992	40
20	Drug-protein conjugates—XVI Biochemical Pharmacology ·James L. Maggs, B.K. Park	1988	14

About James L. Maggs

James L. Maggs is a scholar working on Pharmacology, Biochemistry, Pharmacology, Oncology and Biological Psychiatry, having authored 109 papers that have together received 4.5k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (46 papers), Drug Transport and Resistance Mechanisms (19 papers), Drug-Induced Hepatotoxicity and Protection (18 papers), Malaria Research and Control (18 papers), Estrogen and related hormone effects (16 papers), Drug-Induced Adverse Reactions (13 papers), Inflammatory mediators and NSAID effects (8 papers) and Computational Drug Discovery Methods (7 papers). The work is most often cited by research in Pharmacology (1.5k citations), Pharmacology (698 citations), Computational Theory and Mathematics (592 citations), Toxicology (111 citations) and Biochemistry (206 citations). James L. Maggs has collaborated with scholars based in United Kingdom, United States and Australia. Frequent co-authors include Munir Pirmohamed, Dominic P. Williams, Paul M. O’Neill, Dean J. Naisbitt, B.K. Park, Neil R. Kitteringham, B. Kevin Park, Andrew V. Stachulski, B. Kevin Park and Malcolm D. Tingle. Their work appears in journals such as Chemical Research in Toxicology, Biochemical Pharmacology, Journal of Pharmacology and Experimental Therapeutics, Journal of Medicinal Chemistry and Xenobiotica.

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