Pablo Pelegrı́n

16.1k total citations · 7 hit papers
144 papers, 12.3k citations indexed

About

Pablo Pelegrı́n is a scholar working on Molecular Biology, Immunology and Physiology. According to data from OpenAlex, Pablo Pelegrı́n has authored 144 papers receiving a total of 12.3k indexed citations (citations by other indexed papers that have themselves been cited), including 92 papers in Molecular Biology, 62 papers in Immunology and 40 papers in Physiology. Recurrent topics in Pablo Pelegrı́n's work include Inflammasome and immune disorders (78 papers), Adenosine and Purinergic Signaling (39 papers) and Immune Response and Inflammation (19 papers). Pablo Pelegrı́n is often cited by papers focused on Inflammasome and immune disorders (78 papers), Adenosine and Purinergic Signaling (39 papers) and Immune Response and Inflammation (19 papers). Pablo Pelegrı́n collaborates with scholars based in Spain, United Kingdom and France. Pablo Pelegrı́n's co-authors include Annmarie Surprenant, Feng Shao, Petr Brož, Alberto Baroja‐Mazo, Ana Isabel Gómez Córdoba, Víctoriano Mulero, María Barberà-Cremades, Carlos de Torre‐Minguela, Kate Schroder and Rebecca C. Coll and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Pablo Pelegrı́n

143 papers receiving 12.2k citations

Hit Papers

Pannexin‐1 mediates large pore formation and interleukin‐... 2006 2026 2012 2019 2006 2019 2014 2022 2020 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Pannexin‐1 mediates large pore formation and interleukin‐1β release by the ATP‐gated P2X7 receptor
    2006 1.2k citations Pablo Pelegrı́n, Annmarie Surprenant The EMBO Journal profile →
  2. The gasdermins, a protein family executing cell death and inflammation
    2019 1.2k citations Pablo Pelegrı́n et al. profile →
  3. The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
    2014 640 citations Alberto Baroja‐Mazo, Fatima Martín‐Sánchez et al. profile →
  4. NLRP3 and pyroptosis blockers for treating inflammatory diseases
    2022 484 citations Pablo Pelegrı́n et al. profile →
  5. Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis
    2020 405 citations Pablo Pelegrı́n et al. profile →
  6. MCC950 closes the active conformation of NLRP3 to an inactive state
    2019 328 citations Ana Tapia‐Abellán, Diego Angosto-Bazarra et al. profile →
  7. NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation
    2021 179 citations Pablo Pelegrı́n et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Pablo Pelegrı́n Spain 57 7.8k 4.1k 2.4k 1.3k 1.0k 144 12.3k
Wolfgang G. Junger United States 47 3.1k 0.4× 3.1k 0.8× 2.8k 1.2× 1.7k 1.4× 911 0.9× 116 10.1k
David Brough United Kingdom 50 4.7k 0.6× 2.6k 0.6× 749 0.3× 866 0.7× 656 0.6× 135 8.3k
Friedrich Koch‐Nolte Germany 56 3.6k 0.5× 3.7k 0.9× 4.2k 1.8× 786 0.6× 353 0.3× 255 10.9k
Beverly H. Koller United States 75 9.4k 1.2× 7.0k 1.7× 1.6k 0.7× 2.0k 1.6× 2.3k 2.2× 206 25.1k
Michail V. Sitkovsky United States 62 3.7k 0.5× 6.1k 1.5× 6.6k 2.8× 1.3k 1.0× 785 0.8× 132 13.9k
Anna Rubartelli Italy 57 6.2k 0.8× 5.5k 1.4× 657 0.3× 948 0.7× 800 0.8× 128 11.9k
Christopher A. Gabel United States 39 3.6k 0.5× 1.9k 0.5× 2.1k 0.9× 765 0.6× 779 0.8× 85 7.3k
Marco Idzko Germany 58 3.0k 0.4× 3.3k 0.8× 4.3k 1.8× 801 0.6× 832 0.8× 186 10.6k
Thomas Reinheckel Germany 58 7.1k 0.9× 2.4k 0.6× 484 0.2× 1.7k 1.4× 1.2k 1.1× 187 14.2k
Cormac T. Taylor Ireland 66 7.0k 0.9× 2.9k 0.7× 379 0.2× 1.2k 1.0× 1.2k 1.2× 168 16.2k

Countries citing papers authored by Pablo Pelegrı́n

Since Specialization
Citations

This map shows the geographic impact of Pablo Pelegrı́n's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Pablo Pelegrı́n with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Pablo Pelegrı́n more than expected).

Fields of papers citing papers by Pablo Pelegrı́n

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Pablo Pelegrı́n. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Pablo Pelegrı́n. The network helps show where Pablo Pelegrı́n may publish in the future.

Co-authorship network of co-authors of Pablo Pelegrı́n

This figure shows the co-authorship network connecting the top 25 collaborators of Pablo Pelegrı́n. A scholar is included among the top collaborators of Pablo Pelegrı́n based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Pablo Pelegrı́n. Pablo Pelegrı́n is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Garcı́a, C., Diego Angosto-Bazarra, Fernando Vallejo, et al.. (2024). Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production. Nature Communications. 15(1). 1096–1096. 12 indexed citations
2.
3.
Compan, Vincent & Pablo Pelegrı́n. (2023). Measuring IL-1β Processing by Bioluminescence Sensors: Using a Bioluminescence Resonance Energy Transfer Biosensor. Methods in molecular biology. 2696. 47–53. 1 indexed citations
4.
Weber, Alexander N.R., Ana Tapia‐Abellán, Xiao Liu, et al.. (2022). Effective ex vivo inhibition of cryopyrin-associated periodic syndrome (CAPS)-associated mutant NLRP3 inflammasome by MCC950/CRID3. Lara D. Veeken. 61(10). e299–e313. 11 indexed citations
5.
Baroja‐Mazo, Alberto, et al.. (2022). Characterization of P2X7 Receptors in Human Blood Cells. Methods in molecular biology. 2510. 279–290. 2 indexed citations
6.
Beamer, Edward, James J. Morgan, Mariana Alves, et al.. (2021). Increased expression of the ATP‐gated P2X7 receptor reduces responsiveness to anti‐convulsants during status epilepticus in mice. British Journal of Pharmacology. 179(12). 2986–3006. 27 indexed citations
7.
Pardo, Julián, Maykel Arias, Irmgard Merfort, et al.. (2021). Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases. Cell Death and Disease. 12(12). 1155–1155. 49 indexed citations
8.
Tapia‐Abellán, Ana, Diego Angosto-Bazarra, Cristina Alarcón‐Vila, et al.. (2021). Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation. Science Advances. 7(38). eabf4468–eabf4468. 97 indexed citations
9.
Ionescu, Daniela, Anna Mensa‐Vilaró, Paola Castillo, et al.. (2021). First Description of Late‐Onset Autoinflammatory Disease Due to Somatic NLRC4 Mosaicism. Arthritis & Rheumatology. 74(4). 692–699. 17 indexed citations
10.
Cuevas, Santiago & Pablo Pelegrı́n. (2021). Pyroptosis and Redox Balance in Kidney Diseases. Antioxidants and Redox Signaling. 35(1). 40–60. 37 indexed citations
11.
Silva, Inês V. da, Carlos Cardoso, Helios Martínez‐Banaclocha, et al.. (2020). Aquaporin-3 is involved in NLRP3-inflammasome activation contributing to the setting of inflammatory response. Cellular and Molecular Life Sciences. 78(6). 3073–3085. 41 indexed citations
12.
Hafner‐Bratkovič, Iva, Duško Lainšček, Ana Tapia‐Abellán, et al.. (2018). NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway. Nature Communications. 9(1). 5182–5182. 107 indexed citations
13.
Compan, Vincent & Pablo Pelegrı́n. (2017). Methods to Study Cell Swelling-Induced Inflammasome Activation. Methods in molecular biology. 1714. 191–197. 2 indexed citations
14.
Tyrkalska, Sylwia D., Sergio Candel, Diego Angosto-Bazarra, et al.. (2016). Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins. Nature Communications. 7(1). 12077–12077. 95 indexed citations
15.
Roger, Sébastien, Bilel Jelassi, Isabelle Couillin, et al.. (2014). Understanding the roles of the P2X7 receptor in solid tumour progression and therapeutic perspectives. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1848(10). 2584–2602. 88 indexed citations
16.
López‐Castejón, Gloria, Alberto Baroja‐Mazo, & Pablo Pelegrı́n. (2010). Novel macrophage polarization model: from gene expression to identification of new anti-inflammatory molecules. Cellular and Molecular Life Sciences. 68(18). 3095–3107. 72 indexed citations
17.
Brough, David, Pablo Pelegrı́n, & Nancy J. Rothwell. (2009). Pannexin‐1‐dependent caspase‐1 activation and secretion of IL‐1β is regulated by zinc. European Journal of Immunology. 39(2). 352–358. 47 indexed citations
18.
Pelegrı́n, Pablo, et al.. (2008). P2X7 Receptor Differentially Couples to Distinct Release Pathways for IL-1β in Mouse Macrophage. The Journal of Immunology. 180(11). 7147–7157. 355 indexed citations
19.
Pelegrı́n, Pablo, et al.. (2006). パネキシン-1はATP開口P2X 7 受容体により大ポア形成及びインターロイキン-1β遊離を仲介する. The EMBO Journal. 25(21). 5071–5082. 1 indexed citations
20.
Pelegrı́n, Pablo, Jesús Garcı́a-Castillo, María P. Sepulcre, Víctoriano Mulero, & Juan Meseguer. (2002). Utilización de citoquinas recombinantes para la prevención de infecciones en piscicultura: ¿una realidad o una utopía?. DIGITAL.CSIC (Spanish National Research Council (CSIC)). 18(1). 189–193. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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