Orly Alter

3.9k citations

34 papers · 2.7k indexed · 1 hit paper · h-index 15

Impact in

Computational Mathematics top 0.5%
- Tensor decomposition and applications
Molecular Biology top 5%
- Gene expression and cancer classification
- Bioinformatics and Genomic Networks
- Gene Regulatory Network Analysis
- Genomics and Chromatin Dynamics
- Molecular Biology Techniques and Applications

Papers in ⓘ

Molecular Biology 16
- Gene expression and cancer classification 12
- Genomics and Chromatin Dynamics 9
- Gene Regulatory Network Analysis 8
Artificial Intelligence 8
- Quantum Information and Cryptography 7

Co-authors: Patrick O. Brown (7 shared papers)David Botstein (7 shared papers)Gene H. Golub (5 shared papers)Larsson Omberg (2 shared papers)Gavin Sherlock (1 shared paper)Shirley Zhu (1 shared paper)John X. OʼConnell (1 shared paper)Torsten O. Nielsen (1 shared paper)
Journals: Proceedings of the National Academy of Sciences (7 papers)PLoS ONE (6 papers)Physical Review A (3 papers)APL Bioengineering (3 papers)Journal of Clinical Oncology (2 papers)
Partner nations: United States China Poland

In The Last Decade

Orly Alter

34 papers receiving 2.6k citations

Hit Papers

align trajectories log scale

Singular value decomposition for genome-wide expression data processing and modeling 2000 · 1.4k citations

Peers

Countries citing papers authored by Orly Alter

Since Specialization

Citations

This map shows the geographic impact of Orly Alter's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Orly Alter with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Orly Alter more than expected).

Fields of papers citing papers by Orly Alter

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Orly Alter. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Orly Alter. The network helps show where Orly Alter may publish in the future.

Co-authors

The 25 scholars most cited alongside Orly Alter, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Orly Alter Line = papers co-authored together Orly Alter links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 34 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Singular value decomposition for genome-wide expression data processing and modeling Proceedings of the National Academy of Sciences ·Orly Alter, Patrick O. Brown, David Botstein Hit paper breakdown →	2000	1399
2	Molecular characterisation of soft tissue tumours: a gene expression study The Lancet ·Torsten O. Nielsen, Robert B. West, Sabine C. Linn, Orly Alter, Margaret A. Knowling, John X. OʼConnell, Shirley Zhu, Mike Fero, Gavin Sherlock, Jonathan R. Pollack, Patrick O. Brown, David Botstein, Matt van de Rijn	2002	444
3	Generalized singular value decomposition for comparative analysis of genome-scale expression data sets of two different organisms Proceedings of the National Academy of Sciences ·Orly Alter, Patrick O. Brown, David Botstein	2003	221
4	A tensor higher-order singular value decomposition for integrative analysis of DNA microarray data from different studies Proceedings of the National Academy of Sciences ·Larsson Omberg, Gene H. Golub, Orly Alter	2007	113
5	Variation in gene expression patterns in follicular lymphoma and the response to rituximab Proceedings of the National Academy of Sciences ·Sean P. Bohen, Olga G. Troyanskaya, Orly Alter, Roger A. Warnke, David Botstein, Patrick O. Brown, Ronald Levy	2003	108
6	A Higher-Order Generalized Singular Value Decomposition for Comparison of Global mRNA Expression from Multiple Organisms PLoS ONE ·Sri Priya Ponnapalli, Michael A. Saunders, Charles F. Van Loan, Orly Alter	2011	69
7	Integrative analysis of genome-scale data by using pseudoinverse projection predicts novel correlation between DNA replication and RNA transcription Proceedings of the National Academy of Sciences ·Orly Alter, Gene H. Golub	2004	56
8	Singular value decomposition of genome-scale mRNA lengths distribution reveals asymmetry in RNA gel electrophoresis band broadening Proceedings of the National Academy of Sciences ·Orly Alter, Gene H. Golub	2006	38
9	Reconstructing the pathways of a cellular system from genome-scale signals by using matrix and tensor computations Proceedings of the National Academy of Sciences ·Orly Alter, Gene H. Golub	2005	36
10	Tensor GSVD of Patient- and Platform-Matched Tumor and Normal DNA Copy-Number Profiles Uncovers Chromosome Arm-Wide Patterns of Tumor-Exclusive Platform-Consistent Alterations Encoding for Cell Transformation and Predicting Ovarian Cancer Survival PLoS ONE ·S. Preethi, Theodore E. Schomay, Katherine A. Aiello, Orly Alter	2015	35
11	<title>Processing and modeling genome-wide expression data using singular value decomposition</title> Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE ·Orly Alter, Patrick O. Brown, David Botstein	2001	32
12	GSVD Comparison of Patient-Matched Normal and Tumor aCGH Profiles Reveals Global Copy-Number Alterations Predicting Glioblastoma Multiforme Survival PLoS ONE ·Cheng H. Lee, Benjamin O. Alpert, S. Preethi, Orly Alter	2012	30
13	Global effects of DNA replication and DNA replication origin activity on eukaryotic gene expression Molecular Systems Biology ·Larsson Omberg, Joel R. Meyerson, Kayta Kobayashi, Lucy S. Drury, John F.X. Diffley, Orly Alter	2009	29
14	Inhibition of the Measurement of the Wave Function of a Single Quantum System in Repeated Weak Quantum Nondemolition Measurements Physical Review Letters ·Orly Alter, Y. Yamamoto	1995	17
15	SVD Identifies Transcript Length Distribution Functions from DNA Microarray Data and Reveals Evolutionary Forces Globally Affecting GBM Metabolism PLoS ONE ·Nicolas M. Bertagnolli, Justin A. Drake, Jason M. Tennessen, Orly Alter	2013	14
16	Genomic Signal Processing: From Matrix Algebra to Genetic Networks Methods in molecular biology ·Orly Alter	2007	14
17	Quantum Measurement of a Single System Orly Alter, Y. Yamamoto	2001	13
18	Quantum Zeno effect and the impossibility of determining the quantum state of a single system Physical Review A ·Orly Alter, Y. Yamamoto	1997	12
19	Protective measurement of the wave function of a single squeezed harmonic-oscillator state Physical Review A ·Orly Alter, Y. Yamamoto	1996	11
20	Platform-Independent Genome-Wide Pattern of DNA Copy-Number Alterations Predicting Astrocytoma Survival and Response to Treatment Revealed by the GSVD Formulated as a Comparative Spectral Decomposition PLoS ONE ·Katherine A. Aiello, Orly Alter	2016	8

About Orly Alter

Orly Alter is a scholar working on Molecular Biology, Artificial Intelligence, Atomic and Molecular Physics, and Optics, Genetics and Genetics, having authored 34 papers that have together received 2.7k indexed citations. Recurring topics across this work include Gene expression and cancer classification (12 papers), Genomics and Chromatin Dynamics (9 papers), Gene Regulatory Network Analysis (8 papers), Quantum Mechanics and Applications (7 papers), Quantum Information and Cryptography (7 papers), Glioma Diagnosis and Treatment (5 papers), Cancer Genomics and Diagnostics (4 papers) and Genomic variations and chromosomal abnormalities (4 papers). The work is most often cited by research in Computational Mathematics (156 citations), Molecular Biology (1.7k citations), Gastroenterology (83 citations), Cancer Research (188 citations) and Artificial Intelligence (353 citations). Orly Alter has collaborated with scholars based in United States, China and Poland. Frequent co-authors include Patrick O. Brown, David Botstein, Gene H. Golub, Larsson Omberg, Gavin Sherlock, Shirley Zhu, John X. OʼConnell, Torsten O. Nielsen, Margaret A. Knowling and Jonathan R. Pollack. Their work appears in journals such as Proceedings of the National Academy of Sciences, PLoS ONE, Physical Review A, APL Bioengineering and Journal of Clinical Oncology.

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