Norikazu Ohtake

1.3k citations

57 papers · 1.0k indexed · h-index 18

Endocrine and Autonomic Systems top 5%
Molecular Medicine top 10%
- Antibiotic Resistance in Bacteria 12
Organic Chemistry top 5%
- Synthesis of β-Lactam Compounds 7
Pharmacology top 10%
- Antibiotics Pharmacokinetics and Efficacy 8
Cellular and Molecular Neuroscience
- Neuropeptides and Animal Physiology 16
Molecular Biology
- Receptor Mechanisms and Signaling 21
- Pharmacological Receptor Mechanisms and Effects 9
Physiology
- Nitric Oxide and Endothelin Effects 5
Oncology
- Chemokine receptors and signaling 5

Co-authors: Kazuhito Noguchi Akira Naya Toshihiko Saeki Kenji Ohwaki Makoto Ishikawa Toshiaki Mase Yoshio Ogino Hisashi Iwaasa
Cited by: Endocrine and Autonomic Systems Molecular Medicine Organic Chemistry
Journals: Biochemical and Biophysical Research Communications (1 paper)Journal of Medicinal Chemistry (4 papers)Antimicrobial Agents and Chemotherapy (1 paper)
Partner nations: Japan United States United Kingdom

In The Last Decade

Norikazu Ohtake

56 papers receiving 968 citations

Peers

Countries citing papers authored by Norikazu Ohtake

Since Specialization

Citations

This map shows the geographic impact of Norikazu Ohtake's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Norikazu Ohtake with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Norikazu Ohtake more than expected).

Fields of papers citing papers by Norikazu Ohtake

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Norikazu Ohtake. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Norikazu Ohtake. The network helps show where Norikazu Ohtake may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Norikazu Ohtake, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Norikazu Ohtake Line = papers co-authored together Norikazu Ohtake links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	High-Contrast PET Imaging of Vasopressin V_1B Receptors with a Novel Radioligand, ¹¹C-TASP699 Journal of Nuclear Medicine ·Kazumi Koga,Yuji Nagai,Masayuki Hanyu,Mitsukane Yoshinaga,Shigeyuki Chaki,Norikazu Ohtake,Satoshi Ozaki,Ming‐Rong Zhang,Tetsuya Suhara,Makoto Higuchi	2017	8
2	Identification of highly selective and potent orexin receptor 1 antagonists derived from a dual orexin receptor 1/2 antagonist based on the structural framework of pyrazoylethylbenzamide Bioorganic & Medicinal Chemistry ·Aya Futamura,Dai Nozawa,Yuko Araki,Yunoshin Tamura,Seiken Tokura,Hiroshi Kawamoto,Yuichi Tokumaru,Sora Kakihara,Takeshi Aoki,Norikazu Ohtake	2017	12
3	TASP0434299: A Novel Pyridopyrimidin-4-One Derivative as a Radioligand for Vasopressin V1B Receptor Journal of Pharmacology and Experimental Therapeutics ·K. Koga,Mitsukane Yoshinaga,Y Uematsu,Yuji Nagai,N. Miyakoshi,Yuki Shimoda,Masayuki Fujinaga,Takafumi Minamimoto,Mingming Zhang,Makoto Higuchi,Norikazu Ohtake,Tetsuya Suhara,Shigeyuki Chaki	2016	3
4	Discovery of novel phenylpyridone derivatives as potent and selective MCH1R antagonists Bioorganic & Medicinal Chemistry ·Yuji Haga,Sayaka Mizutani,Akira Naya,Hiroyuki Kishino,Hisashi Iwaasa,Masahiko Ito,Junko Itô,Minoru Moriya,Nagaaki Sato,Norihiro Takenaga,Akane Ishihara,Shigeru Tokita,Akio Kanatani,Norikazu Ohtake	2010	8
5	Melanin-concentrating hormone 1-receptor antagonist suppresses body weight gain correlated with high receptor occupancy levels in diet-induced obesity mice European Journal of Pharmacology ·Masahiko Ito,Akane Ishihara,Akira Gomori,Shinichiro Egashira,Hiroko Matsushita,Satoshi Mashiko,Junko Itô,Makoto Ito,Kazuho Nakase,Yuji Haga,Hisashi Iwaasa,Takao Suzuki,Norikazu Ohtake,Minoru Moriya,Nagaaki Sato,Douglas J. MacNeil,Norihiro Takenaga,Shigeru Tokita,Akio Kanatani	2009	18
6	Discovery and structure–activity relationships of a novel class of quinazoline glucokinase activators Bioorganic & Medicinal Chemistry Letters ·Tomoharu Iino,Yasuhiro Sasaki,Makoto Bamba,Morihiro Mitsuya,Akio Ohno,Kenji Kamata,Hideka Hosaka,Hiroko Maruki,Mayumi Futamura,Riki Yoshimoto,Sumika Ohyama,Kaori Sasaki,Masato Chiba,Norikazu Ohtake,Yasufumi Nagata,Jun‐ichi Eiki,T. Nishimura	2009	33
7	Syntheses and structure–activity relationships of novel, potent, and selective trans-2-[3-oxospiro[isobenzofuran-1(3H),1′-cyclohexan]-4′-yl]benzimidazole NPY Y5 receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Yoshio Ogino,Norikazu Ohtake,Yoshikazu Nagae,Kenji Matsuda,Makoto Ishikawa,Minoru Moriya,Maki Kanesaka,Yuko Mitobe,Junko Itô,Tetsuya Kanno,Akane Ishihara,Hisashi Iwaasa,Tomoyuki Ohe,Akio Kanatani,Takehiro Fukami	2008	19
8	Identification of a Novel 4-Aminomethylpiperidine Class of M₃Muscarinic Receptor Antagonists and Structural Insight into Their M₃Selectivity Journal of Medicinal Chemistry ·Yufu Sagara,Takeshi Sagara,Minaho Uchiyama,Sachie Otsuki,Toshifumi Kimura,Toru Fujikawa,Kazuhito Noguchi,Norikazu Ohtake	2006	8
9	Convenient synthesis of 2-alkylamino-6-carboxy-5,7-diarylcyclopenteno[1,2-b]pyridines via direct acylamination with imidoyl chlorides Tetrahedron ·Hirobumi Takahashi,(unknown),Takehiro Fukami,Hisaki Kojima,Takeru Yamakawa,Hiroyuki Takahashi,Toshihiro Sakamoto,T. Nishimura,Masayuki Nakamura,Takashi Yosizumi,Kenji Niiyama,Norikazu Ohtake,Takashi Hayama	2005	5
10	N- Acyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline: The first orexin-2 receptor selective non-peptidic antagonist Bioorganic & Medicinal Chemistry Letters ·Masaaki Hirose,Shinichiro Egashira,Yasuhiro Gotô,Takashi Hashihayata,Norikazu Ohtake,Hisashi Iwaasa,M. Hata,Takehiro Fukami,Akio Kanatani,Kôji Yamada	2003	84
11	Identification of novel muscarinic M3 selective antagonists with a conformationally restricted Hyp-Pro spacer Bioorganic & Medicinal Chemistry Letters ·Yufu Sagara,Toshifumi Kimura,Toru Fujikawa,Kazuhito Noguchi,Norikazu Ohtake	2003	12
12	Structure–activity relationships of xanthene carboxamides, novel CCR1 receptor antagonists Bioorganic & Medicinal Chemistry ·Akira Naya,Makoto Ishikawa,Kenji Matsuda,Kenji Ohwaki,Toshihiko Saeki,Kazuhito Noguchi,Norikazu Ohtake	2003	56
13	Structure–Activity Relationships of 1β-Methyl-2-(5-phenylpyrrolidin-3-ylthio)carbapenems Bioorganic & Medicinal Chemistry ·Hiroki Sato,Hiroki Sakoh,Takashi Hashihayata,Hideaki Imamura,Norikazu Ohtake,Aya Shimizu,Yuichi Sugimoto,Shunji Sakuraba,Rie Bamba‐Nagano,Koji Yamada,Terutaka Hashizume,Hajime Morishima	2002	8
14	Identification of a Potent and Nonpeptidyl CCR3 Antagonist Biochemical and Biophysical Research Communications ·Toshihiko Saeki,Kenji Ohwaki,Akira Naya,Kensuke Kobayashi,Makoto Ishikawa,Norikazu Ohtake,Kazuhito Noguchi	2001	22
15	Structure–activity relationships of trans-3,5-disubstituted pyrrolidinylthio-1β-methylcarbapenems. Part 2: J-111,225, J-114,870, J-114,871 and related compounds Bioorganic & Medicinal Chemistry Letters ·Hideaki Imamura,Norikazu Ohtake,Aya Shimizu,Hiroki Sato,Yuichi Sugimoto,Shunji Sakuraba,Hideo Kiyonaga,Chihiro Suzuki-Sato,Masato Nakano,Rie Nagano,Koji Yamada,Terutaka Hashizume,Hajime Morishima	2000	6
16	Discovery of a muscarinic M3 receptor antagonist with high selectivity for M3 over M2 receptors among 2-[(1S,3S)-3-sulfonylaminocyclopentyl]phenylacetamide derivatives Bioorganic & Medicinal Chemistry ·Morihiro Mitsuya,Yoshio Ogino,Kumiko Kawakami,Minaho Uchiyama,Toshifumi Kimura,Tomoshige Numazawa,Takuro Hasegawa,Norikazu Ohtake,Kazuhito Noguchi,Toshiaki Mase	2000	17
17	Structure–activity relationships of trans-3,5-disubstituted pyrrolidinylthio-1β-methylcarbapenems. Part 1: J-111,347 and related compounds Bioorganic & Medicinal Chemistry Letters ·Hideaki Imamura,Norikazu Ohtake,Aya Shimizu,Hideki Jona,Hiroki Sato,Rie Nagano,Ryosuke Ushijima,Koji Yamada,Terutaka Hashizume,Hajime Morishima	2000	17
18	1.BETA.-Methyl-2-(5-substituted pyrrolidin-3-ylthio)carbapenems; 1. Synthesis and Antibacterial Activity of B0-2502A and lts Related Compoundsf. The Journal of Antibiotics ·Norikazu Ohtake,Koji Yamada,EIICHI MANO,Osamu Okamoto,Ryosuke Ushijima,Susumu Nakagawa	1997	5
19	1,a-Methyl-2-(5-substituted pyrrolidin-3-ylthio)carbapenems; 3. Synthesis and Antibacterial Activity of BO-2727 and Its Related Compounds. The Journal of Antibiotics ·Norikazu Ohtake,Osamu Okamoto,Ryuji Mitomo,Y. Kato,Katsumi Yamamoto,Yuji Haga,Hiroshi Fukatsu,Susumu Nakagawa	1997	14
20	Resistance to a new catecholic cepbem, BO-1341, in Pseudomonas aeruginosa PAO Journal of Antimicrobial Chemotherapy ·N Hazumi,Kouji Matsnda,Minorn Sanada,Norikazu Ohtake,Nobuo Tanaka	1992	5

About Norikazu Ohtake

Norikazu Ohtake is a scholar working on Molecular Medicine, Cellular and Molecular Neuroscience and Endocrine and Autonomic Systems, having authored 57 papers that have together received 1.0k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (21 papers), Neuropeptides and Animal Physiology (16 papers), Antibiotic Resistance in Bacteria (12 papers), Pharmacological Receptor Mechanisms and Effects (9 papers), Antibiotics Pharmacokinetics and Efficacy (8 papers), Synthesis of β-Lactam Compounds (7 papers), Nitric Oxide and Endothelin Effects (5 papers) and Chemokine receptors and signaling (5 papers). The work is most often cited by research in Endocrine and Autonomic Systems (115 citations), Molecular Medicine (72 citations) and Organic Chemistry (408 citations). Norikazu Ohtake has collaborated with scholars based in Japan, United States and United Kingdom. Frequent co-authors include Kazuhito Noguchi, Akira Naya, Toshihiko Saeki, Kenji Ohwaki, Makoto Ishikawa, Toshiaki Mase, Yoshio Ogino, Hisashi Iwaasa, Takehiro Fukami and Kensuke Kobayashi. Their work appears in journals such as Biochemical and Biophysical Research Communications, Journal of Medicinal Chemistry and Antimicrobial Agents and Chemotherapy.

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