Jun‐ichi Eiki

1.6k citations

28 papers · 1.3k indexed · h-index 17

Impact in

Endocrine and Autonomic Systems top 5%
- Regulation of Appetite and Obesity
Endocrinology, Diabetes and Metabolism top 5%
- Diabetes Treatment and Management
- Diabetes Management and Research
- Diet, Metabolism, and Disease

Papers in ⓘ

Surgery 23
- Pancreatic function and diabetes 23
Molecular Biology 16
- Metabolism, Diabetes, and Cancer 12
- Biochemical and Molecular Research 5

Co-authors: T. Nishimura (14 shared papers)Yasufumi Nagata (12 shared papers)Kenji Kamata (6 shared papers)Morihiro Mitsuya (4 shared papers)Bei B. Zhang (4 shared papers)Ambrose A. Dunn-Meynell (3 shared papers)Barry E. Levin (3 shared papers)Sumika Ohyama (14 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (5 papers)Bioorganic & Medicinal Chemistry (3 papers)Diabetes (2 papers)Journal of Diabetes Investigation (2 papers)Endocrinology (1 paper)
Partner nations: Japan United States

In The Last Decade

Jun‐ichi Eiki

28 papers receiving 1.3k citations

Peers

Countries citing papers authored by Jun‐ichi Eiki

Since Specialization

Citations

This map shows the geographic impact of Jun‐ichi Eiki's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jun‐ichi Eiki with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jun‐ichi Eiki more than expected).

Fields of papers citing papers by Jun‐ichi Eiki

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jun‐ichi Eiki. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jun‐ichi Eiki. The network helps show where Jun‐ichi Eiki may publish in the future.

Co-authors

The 25 scholars most cited alongside Jun‐ichi Eiki, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jun‐ichi Eiki Line = papers co-authored together Jun‐ichi Eiki links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 28 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Structural Basis for Allosteric Regulation of the Monomeric Allosteric Enzyme Human Glucokinase Structure ·Kenji Kamata, Morihiro Mitsuya, T. Nishimura, Jun‐ichi Eiki, Yasufumi Nagata	2004	399
2	Glucokinase Is a Critical Regulator of Ventromedial Hypothalamic Neuronal Glucosensing Diabetes ·Ling Kang, Ambrose A. Dunn-Meynell, Vanessa H. Routh, Lawrence D. Gaspers, Yasufumi Nagata, T. Nishimura, Jun‐ichi Eiki, Bei B. Zhang, Barry E. Levin	2006	153
3	Relationship among Brain and Blood Glucose Levels and Spontaneous and Glucoprivic Feeding Journal of Neuroscience ·Ambrose A. Dunn-Meynell, Nicole M. Sanders, Douglas S. Compton, Thomas Becker, Jun‐ichi Eiki, Bei B. Zhang, Barry E. Levin	2009	113
4	An Allosteric Activator of Glucokinase Impairs the Interaction of Glucokinase and Glucokinase Regulatory Protein and Regulates Glucose Metabolism Journal of Biological Chemistry ·Mayumi Futamura, Hideka Hosaka, Akito Kadotani, Hiroko Shimazaki, Kaori Sasaki, Sumika Ohyama, T. Nishimura, Jun‐ichi Eiki, Yasufumi Nagata	2006	86
5	Ventromedial Hypothalamic Glucokinase Is an Important Mediator of the Counterregulatory Response to Insulin-Induced Hypoglycemia Diabetes ·Barry E. Levin, Thomas Becker, Jun‐ichi Eiki, Bei B. Zhang, Ambrose A. Dunn-Meynell	2008	64
6	Discovery of potent and orally active 3-alkoxy-5-phenoxy-N-thiazolyl benzamides as novel allosteric glucokinase activators Bioorganic & Medicinal Chemistry ·Tomoharu Iino, Daisuke Tsukahara, Kenji Kamata, Kaori Sasaki, Sumika Ohyama, Hideka Hosaka, Takuro Hasegawa, Masato Chiba, Yasufumi Nagata, Jun‐ichi Eiki, T. Nishimura	2009	55
7	Impact of Small-Molecule Glucokinase Activator on Glucose Metabolism and β-Cell Mass Endocrinology ·Akinobu Nakamura, Yasuo Terauchi, Sumika Ohyama, Junko Kubota, Hiroko Shimazaki, Tadahiro Nambu, Iseki Takamoto, Naoto Kubota, Jun‐ichi Eiki, Narihito Yoshioka, Takashi Kadowaki, Takao Koike	2008	53
8	Discovery of novel 2-(pyridine-2-yl)-1H-benzimidazole derivatives as potent glucokinase activators Bioorganic & Medicinal Chemistry Letters ·Makoto Ishikawa, Katsumasa Nonoshita, Yoshio Ogino, Yoshikazu Nagae, Daisuke Tsukahara, Hideka Hosaka, Hiroko Maruki, Sumika Ohyama, Riki Yoshimoto, Kaori Sasaki, Yasufumi Nagata, Jun‐ichi Eiki, T. Nishimura	2009	46
9	Structure–activity relationships of 3,5-disubstituted benzamides as glucokinase activators with potent in vivo efficacy Bioorganic & Medicinal Chemistry ·Tomoharu Iino, Noriaki Hashimoto, Kaori Sasaki, Sumika Ohyama, Riki Yoshimoto, Hideka Hosaka, Takuro Hasegawa, Masato Chiba, Yasufumi Nagata, Jun‐ichi Eiki, T. Nishimura	2009	45
10	Identification of novel and potent 2-amino benzamide derivatives as allosteric glucokinase activators Bioorganic & Medicinal Chemistry Letters ·T. Nishimura, Tomoharu Iino, Morihiro Mitsuya, Makoto Bamba, Hitomi Watanabe, Daisuke Tsukahara, Kenji Kamata, Kaori Sasaki, Sumika Ohyama, Hideka Hosaka, Mayumi Futamura, Yasufumi Nagata, Jun‐ichi Eiki	2009	38
11	Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators Bioorganic & Medicinal Chemistry Letters ·Morihiro Mitsuya, Kenji Kamata, Makoto Bamba, Hitomi Watanabe, Yasuhiro Sasaki, Kaori Sasaki, Sumika Ohyama, Hideka Hosaka, Yasufumi Nagata, Jun‐ichi Eiki, T. Nishimura	2009	38
12	Discovery and structure–activity relationships of a novel class of quinazoline glucokinase activators Bioorganic & Medicinal Chemistry Letters ·Tomoharu Iino, Yasuhiro Sasaki, Makoto Bamba, Morihiro Mitsuya, Akio Ohno, Kenji Kamata, Hideka Hosaka, Hiroko Maruki, Mayumi Futamura, Riki Yoshimoto, Sumika Ohyama, Kaori Sasaki, Masato Chiba, Norikazu Ohtake, Yasufumi Nagata, Jun‐ichi Eiki, T. Nishimura	2009	33
13	Chronic treatment with a glucokinase activator delays the onset of hyperglycaemia and preserves beta cell mass in the Zucker diabetic fatty rat Diabetologia ·Mayumi Futamura, Jun Yao, X. Li, Raynald Bergeron, J.-L. Tran, Emanuel Zycband, John Woods, Yuhua Zhu, Qing Shao, Hiroko Maruki‐Uchida, Hiroko Goto-Shimazaki, Ronald B. Langdon, Mark D. Erion, Jun‐ichi Eiki, Yun Zhou	2012	33
14	The design and optimization of a series of 2-(pyridin-2-yl)-1H-benzimidazole compounds as allosteric glucokinase activators Bioorganic & Medicinal Chemistry ·Keiji Takahashi, Noriaki Hashimoto, Chisato Nakama, Kenji Kamata, Kaori Sasaki, Riki Yoshimoto, Sumika Ohyama, Hideka Hosaka, Hiroko Maruki, Yasufumi Nagata, Jun‐ichi Eiki, T. Nishimura	2009	30
15	Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs Molecular Pharmacology ·Jun‐ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, T. Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon, Joel P. Berger	2011	25
16	Comorbidities and complications in Japanese patients with type 2 diabetes mellitus: Retrospective analyses of J-DREAMS, an advanced electronic medical records database Diabetes Research and Clinical Practice ·Mitsuru Ohsugi, Jun‐ichi Eiki, Kristy Iglay, Jumpei Tetsuka, Shigeru Tokita, Kohjiro Ueki	2021	24
17	A small-molecule glucokinase activator lowers blood glucose in the sulfonylurea-desensitized rat European Journal of Pharmacology ·Sumika Ohyama, Hiroki Takano, Tomoharu Iino, T. Nishimura, Yun-Ping Zhou, Ronald B. Langdon, Bei B. Zhang, Jun‐ichi Eiki	2010	18
18	A selective small molecule glucagon-like peptide-1 secretagogue acting via depolarization-coupled Ca2+ influx Journal of Endocrinology ·Jun‐ichi Eiki, Kaori Saeki, Norihiro Nagano, Tomoharu Iino, Mari Yonemoto, Yoko Takayenoki-Iino, Satoru Ito, T. Nishimura, Yoshiyuki Satô, Makoto Bamba, Hitomi Watanabe, Kaori Sasaki, Sumika Ohyama, Akio Kanatani, Toshio Nagase, Toshihiko Yada	2009	16
19	Effect of long-term treatment with a small-molecule glucokinase activator on glucose metabolism, lipid profiles and hepatic function Journal of Diabetes Investigation ·Akinobu Nakamura, Hiroko Shimazaki, Sumika Ohyama, Jun‐ichi Eiki, Yasuo Terauchi	2011	13
20	Metabolic activation of N-thiazol-2-yl benzamide as glucokinase activators: Impacts of glutathione trapping on covalent binding Bioorganic & Medicinal Chemistry Letters ·Tomoharu Iino, Noriaki Hashimoto, Takuro Hasegawa, Masato Chiba, Jun‐ichi Eiki, T. Nishimura	2010	12

About Jun‐ichi Eiki

Jun‐ichi Eiki is a scholar working on Surgery, Molecular Biology, Endocrinology, Diabetes and Metabolism, Physiology and Endocrine and Autonomic Systems, having authored 28 papers that have together received 1.3k indexed citations. Recurring topics across this work include Pancreatic function and diabetes (23 papers), Metabolism, Diabetes, and Cancer (12 papers), Diabetes Treatment and Management (9 papers), Diabetes Management and Research (7 papers), Erythrocyte Function and Pathophysiology (6 papers), Biochemical and Molecular Research (5 papers), Regulation of Appetite and Obesity (3 papers) and Pharmacogenetics and Drug Metabolism (2 papers). The work is most often cited by research in Endocrine and Autonomic Systems (230 citations), Endocrinology, Diabetes and Metabolism (423 citations), Surgery (822 citations), Molecular Biology (791 citations) and Physiology (227 citations). Jun‐ichi Eiki has collaborated with scholars based in Japan and United States. Frequent co-authors include T. Nishimura, Yasufumi Nagata, Kenji Kamata, Morihiro Mitsuya, Bei B. Zhang, Ambrose A. Dunn-Meynell, Barry E. Levin, Sumika Ohyama, Hideka Hosaka and Kaori Sasaki. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Bioorganic & Medicinal Chemistry, Diabetes, Journal of Diabetes Investigation and Endocrinology.

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