Nicholas McGranahan

42.4k total citations · 6 hit papers
67 papers, 9.4k citations indexed

About

Nicholas McGranahan is a scholar working on Cancer Research, Molecular Biology and Oncology. According to data from OpenAlex, Nicholas McGranahan has authored 67 papers receiving a total of 9.4k indexed citations (citations by other indexed papers that have themselves been cited), including 49 papers in Cancer Research, 38 papers in Molecular Biology and 21 papers in Oncology. Recurrent topics in Nicholas McGranahan's work include Cancer Genomics and Diagnostics (49 papers), Cancer Immunotherapy and Biomarkers (11 papers) and Epigenetics and DNA Methylation (10 papers). Nicholas McGranahan is often cited by papers focused on Cancer Genomics and Diagnostics (49 papers), Cancer Immunotherapy and Biomarkers (11 papers) and Epigenetics and DNA Methylation (10 papers). Nicholas McGranahan collaborates with scholars based in United Kingdom, United States and Denmark. Nicholas McGranahan's co-authors include Charles Swanton, Rebecca A. Burrell, Jiří Bártek, Nicolai J. Birkbak, Rachel Rosenthal, Javier Herrero, Barry S. Taylor, Elza C. de Bruin, Zoltán Szállási and Reuben S. Harris and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Nicholas McGranahan

64 papers receiving 9.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future

2017 1.8k citations Nicholas McGranahan, Charles Swanton profile →
The causes and consequences of genetic heterogeneity in cancer evolution

2013 1.6k citations Rebecca A. Burrell, Nicholas McGranahan et al. Nature profile →
Biological and Therapeutic Impact of Intratumor Heterogeneity in Cancer Evolution

2015 765 citations Nicholas McGranahan, Charles Swanton profile →
Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis

2017 662 citations Kevin Litchfield, Rachel Rosenthal et al. profile →
deconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution

2016 630 citations Rachel Rosenthal, Nicholas McGranahan et al. Genome biology profile →
Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

2015 432 citations Nicholas McGranahan, Nicolai J. Birkbak et al. profile →

Peers

Countries citing papers authored by Nicholas McGranahan

Since Specialization

Citations

This map shows the geographic impact of Nicholas McGranahan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nicholas McGranahan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nicholas McGranahan more than expected).

Fields of papers citing papers by Nicholas McGranahan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nicholas McGranahan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nicholas McGranahan. The network helps show where Nicholas McGranahan may publish in the future.

Co-authorship network of co-authors of Nicholas McGranahan

This figure shows the co-authorship network connecting the top 25 collaborators of Nicholas McGranahan. A scholar is included among the top collaborators of Nicholas McGranahan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nicholas McGranahan. Nicholas McGranahan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Clone copy number diversity is linked to survival in lung cancer 2025 ·Nature ·Piotr Pawlik, Kristiana Grigoriadis, Abigail Bunkum, (unknown), Alexander M. Frankell, Carlos Martínez‐Ruiz, Takahiro Karasaki, Ariana Huebner, Andrew Rowan, Jasmin Fisher, Allan Hackshaw, Charles Swanton, Simone Zaccaria, Nicholas McGranahan	1
2	Integrating model systems and genomic insights to decipher mechanisms of cancer metastasis 2025 ·Nature Reviews Genetics ·Michelle Leung, Charles Swanton, Nicholas McGranahan	4
3	Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution 2024 ·Nature Communications ·Michelle Dietzen, Hao-Ran Zhai, Olivia Lucas, Oriol Pich, Christopher Barrington, Wei-Ting Lu, Sophia Ward, Yanping Guo, Robert E. Hynds, Simone Zaccaria, Charles Swanton, Nicholas McGranahan, Nnennaya Kanu	3
4	LBA55 An ultra-sensitive and specific ctDNA assay provides novel pre-operative disease stratification in early stage lung cancer 2023 ·Annals of Oncology ·James R. Black, Alexander M. Frankell, Selvaraju Veeriah, (unknown), Mark S. Hill, Charles W. Abbott, (unknown), Bo Li, Rui Chen, Maise Al Bakir, (unknown), Ariana Huebner, Mariam Jamal‐Hanjani, Nicholas McGranahan, Charles Swanton	6
5	Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology 2023 ·Nature Communications ·Oliver J. Ziff, Jacob Neeves, Jamie S. Mitchell, Giulia E. Tyzack, Carlos Martínez‐Ruiz, Raphaëlle Luisier, Anob M. Chakrabarti, Nicholas McGranahan, Kevin Litchfield, Simon J. Boulton, Ammar Al‐Chalabi, Gavin Kelly, Jack Humphrey, Rickie Patani	36
6	CONIPHER: a computational framework for scalable phylogenetic reconstruction with error correction 2023 ·Nature Protocols ·Kristiana Grigoriadis, Ariana Huebner, Abigail Bunkum, Emma Colliver, Alexander M. Frankell, Mark S. Hill, Kerstin Thol, Nicolai J. Birkbak, Charles Swanton, Simone Zaccaria, Nicholas McGranahan	9
7	Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity 2023 ·PLoS Computational Biology ·Thomas B.K. Watkins, Emma Colliver, Matthew R. Huska, Tom L. Kaufmann, Emilia L. Lim, (unknown), Kerstin Haase, Peter Van Loo, Charles Swanton, Nicholas McGranahan, Roland F. Schwarz	4
8	LBA72 DARWIN II: Deciphering anti-tumour response and resistance to immunotherapy with intratumour heterogeneity in NSCLC 2023 ·Annals of Oncology ·Crispin T. Hiley, (unknown), T. Ahmad, Matthew Krebs, Dean A. Fennell, Shobhit Baijal, Nicola Steele, Gillian Price, (unknown), (unknown), Carla Castignani, Katey S.S. Enfield, Benny Chain, Sergio A. Quezada, George Kassiotis, Kevin Litchfield, Nicholas McGranahan, Allan Hackshaw, Mariam Jamal‐Hanjani, Charles Swanton	0
9	Treatment Represents a Key Driver of Metastatic Cancer Evolution 2022 ·Cancer Research ·(unknown), Johanne Ahrenfeldt, Mateo Sokač, Judit Kisistók, Martin K. Thomsen, Lasse Maretty, Nicholas McGranahan, Nicolai J. Birkbak	17
10	The BCL-2 family member BOK promotes KRAS-driven lung cancer progression in a p53-dependent manner 2022 ·Oncogene ·(unknown), Enkhtsetseg Munkhbaatar, Ulrike Höckendorf, Michelle Dietzen, (unknown), Martina Anton, Anne Jacob, Katja Steiger, Wilko Weichert, Luka Brčić, Nicholas McGranahan, Caterina Branca, Thomas Kaufmann, Michael A. Dengler, Philipp J. Jost	10
11	Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive transfer with tumor-infiltrating lymphocytes in melanoma 2021 ·UCL Discovery (University College London) ·(unknown), (unknown), Siri Tvingsholm, Annie Borch, Arianna Draghi, Michael D. Crowther, (unknown), (unknown), (unknown), Anne-Mette Bjerregaard, Amalie Kai Bentzen, Andrea Marion Marquard, Zoltán Szállási, Nicholas McGranahan, Rikke Andersen, Morten Nielsen, Göran Jönsson, Marco Donia, Inge Marie Svane, Sine Reker Hadrup	77
12	1184P Necroptosis establishes an inflammatory tumor immune microenvironment acting as tumor suppressor in lung adenocarcinoma 2021 ·Annals of Oncology ·(unknown), (unknown), Michelle Dietzen, Sebastian Vosberg, Enkhtsetseg Munkhbaatar, Nicholas McGranahan, Philipp J. Jost	0
13	Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner 2019 ·Proceedings of the National Academy of Sciences ·Ralitsa R. Madsen, Rachel Knox, Wayne Pearce, Saioa López, Betania Mahler‐Araujo, Nicholas McGranahan, Bart Vanhaesebroeck, Robert K. Semple	42
14	APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution 2018 ·UCL Discovery (University College London) ·Subramanian Venkatesan, Rachel Rosenthal, Nnennaya Kanu, Nicholas McGranahan, (unknown), (unknown), J.D. Hare, (unknown), Charles Swanton	1
15	APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability 2017 ·Cancer Discovery ·Laurent Sansregret, James O. Patterson, Sally M. Dewhurst, Carlos López‐García, André Koch, Nicholas McGranahan, William Chong Hang Chao, David J. Barry, Andrew Rowan, Rachael Instrell, Stuart Horswell, Michael Way, Michael Howell, Martin R. Singleton, René H. Medema, Paul Nurse, Mark Petronczki, Charles Swanton	80
16	DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer 2016 ·Genome biology ·Nnennaya Kanu, Maria Antonietta Cerone, Gerald Goh, Lykourgos‐Panagiotis Zalmas, Jiřina Bártková, Michelle Dietzen, Nicholas McGranahan, Rebecca F. Rogers, Emily K. Law, Irina Gromova, Maik Kschischo, Michael I. Walton, Olivia W. Rossanese, Jiří Bártek, Reuben S. Harris, Subramanian Venkatesan, Charles Swanton	118
17	Tracking the Genomic Evolution of Esophageal Adenocarcinoma through Neoadjuvant Chemotherapy 2015 ·Cancer Discovery ·Nirupa Murugaesu, Gareth A. Wilson, Nicolai J. Birkbak, Thomas B.K. Watkins, Nicholas McGranahan, Sacheen Kumar, Nima Abbassi‐Ghadi, Max Salm, Richard Mitter, Stuart Horswell, Andrew Rowan, Benjamin Phillimore, Jennifer Biggs, Sharmin Begum, Nik Matthews, Daniel Hochhauser, George B. Hanna, Charles Swanton	178
18	Tolerance of Whole-Genome Doubling Propagates Chromosomal Instability and Accelerates Cancer Genome Evolution 2014 ·Cancer Discovery ·Sally M. Dewhurst, Nicholas McGranahan, Rebecca A. Burrell, Andrew J. Rowan, Eva Grönroos, David Endesfelder, Tejal Joshi, Dmitri Mouradov, Peter Gibbs, Robyn L. Ward, Nicholas J. Hawkins, Zoltán Szállási, Oliver M. Sieber, Charles Swanton	287
19	Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER+ Breast Cancer 2014 ·Cancer Research ·David Endesfelder, Rebecca A. Burrell, Nnennaya Kanu, Nicholas McGranahan, Michael Howell, Peter J. Parker, Julian Downward, Charles Swanton, Maik Kschischo	47
20	A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables 2011 ·Oncotarget ·David Endesfelder, Nicholas McGranahan, Nicolai J. Birkbak, Zoltán Szállási, Maik Kschischo, Trevor A. Graham, Charles Swanton	7

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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