Nicholas H. Varvel

2.7k citations

26 papers · 2.1k indexed · h-index 18

Neurology top 0.5%
Physiology top 2%
Molecular Biology
Cellular and Molecular Neuroscience top 5%
Immunology top 10%

Co-authors: Bruce T. Lamb Raymond Dingledine Richard M. Ransohoff Karl Herrup Guixiang Xu Astrid E. Cardona F. Edward Dudek Sung‐Ho Lee
Topics: Neuroinflammation and Neurodegeneration Mechanisms (15 papers)Alzheimer's disease research and treatments (14 papers)Neuroscience and Neuropharmacology Research (7 papers)
Cited by: Neurology Biological Psychiatry Developmental Neuroscience
Journals: Proceedings of the National Academy of Sciences Journal of Clinical Investigation The Journal of Experimental Medicine
Partner nations: United States Germany Netherlands

In The Last Decade

Nicholas H. Varvel

25 papers receiving 2.1k citations

Peers

Countries citing papers authored by Nicholas H. Varvel

Since Specialization

Citations

This map shows the geographic impact of Nicholas H. Varvel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nicholas H. Varvel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nicholas H. Varvel more than expected).

Fields of papers citing papers by Nicholas H. Varvel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nicholas H. Varvel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nicholas H. Varvel. The network helps show where Nicholas H. Varvel may publish in the future.

Co-authorship network of co-authors of Nicholas H. Varvel

This figure shows the co-authorship network connecting the top 25 collaborators of Nicholas H. Varvel. A scholar is included among the top collaborators of Nicholas H. Varvel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nicholas H. Varvel. Nicholas H. Varvel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Disease modification upon 2 weeks of tofacitinib treatment in a mouse model of chronic epilepsy 2025 ·Science Translational Medicine ·(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Barry Schoenike,Claudia Espinosa‐García,Felipe Paredes,Nicholas H. Varvel,Raymond Dingledine,Jamie Maguire,Avtar Roopra	1
2	Brain-invading monocytes promote seizure-associated cognitive deficits and neurodegeneration 2025 ·Neuropharmacology ·(unknown),(unknown),Raymond Dingledine,Nicholas H. Varvel	0
3	Pharmacological inhibition of the inflammatory receptor CCR2 relieves the early deleterious consequences of status epilepticus 2023 ·Scientific Reports ·(unknown),Wenyi Wang,Raymond Dingledine,Nicholas H. Varvel	9
4	Preclinical development of an EP2 antagonist for post-seizure cognitive deficits 2022 ·Neuropharmacology ·Nicholas H. Varvel,(unknown),Claudia Espinosa‐García,Steven K. Duddy,Ronald B. Franklin,Avijit Banik,(unknown),(unknown),(unknown),Tage Honoré,Thota Ganesh,Raymond Dingledine	9
5	Progranulin loss results in sex-dependent dysregulation of the peripheral and central immune system 2022 ·Frontiers in Immunology ·Madelyn C. Houser,(unknown),Rebecca L. Wallings,Cody E. Keating,Kathryn P. MacPherson,Mary K. Herrick,George T. Kannarkat,Sean D. Kelly,Jianjun Chang,Nicholas H. Varvel,Jessica E. Rexach,Malú G. Tansey	14
6	Peripheral Myeloid Cell EP2 Activation Contributes to the Deleterious Consequences of Status Epilepticus 2020 ·Journal of Neuroscience ·Nicholas H. Varvel,Claudia Espinosa‐García,Sarah Hunter-Chang,Di Chen,(unknown),(unknown),(unknown),Thota Ganesh,Raymond Dingledine	22
7	Functional Analysis of Brain-Engrafted Monocytes After Microglia Ablation in Mouse Models 2019 ·Methods in molecular biology ·Nicholas H. Varvel,Richard M. Ransohoff,Jonas J. Neher	2
8	Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer’s disease 2015 ·The Journal of Experimental Medicine ·Nicholas H. Varvel,Stefan Grathwohl,Karoline Degenhardt,(unknown),(unknown),Mathias Jucker,Jonas J. Neher	77
9	When and How Do Seizures Kill Neurons, and Is Cell Death Relevant to Epileptogenesis? 2014 ·Advances in experimental medicine and biology ·Raymond Dingledine,Nicholas H. Varvel,F. Edward Dudek	177
10	Candidate Drug Targets for Prevention or Modification of Epilepsy 2014 ·The Annual Review of Pharmacology and Toxicology ·Nicholas H. Varvel,Jianxiong Jiang,Raymond Dingledine	70
11	Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events 2013 ·Neurobiology of Disease ·Kiran Bhaskar,Nicole Maphis,Guixiang Xu,Nicholas H. Varvel,Olga N. Kokiko‐Cochran,Jason P. Weick,Susan M. Staugaitis,Astrid E. Cardona,Richard M. Ransohoff,Karl Herrup,Bruce T. Lamb	119
12	Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells 2012 ·Proceedings of the National Academy of Sciences ·Nicholas H. Varvel,Stefan Grathwohl,Frank Baumann,Christian Liebig,(unknown),Bianca Brawek,Dietmar Rudolf Thal,Israel Charo,Frank L. Heppner,Adriano Aguzzi,Olga Garaschuk,Richard M. Ransohoff,Mathias Jucker	203
13	The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain 2011 ·Acta Neuropathologica ·Tsuyoshi Hamaguchi,Yvonne S. Eisele,Nicholas H. Varvel,Bruce T. Lamb,Lary C. Walker,Mathias Jucker	81
14	CX3CR1 Deficiency Alters Microglial Activation and Reduces Beta-Amyloid Deposition in Two Alzheimer's Disease Mouse Models 2010 ·American Journal Of Pathology ·Sung‐Ho Lee,Nicholas H. Varvel,(unknown),Guixiang Xu,Astrid E. Cardona,Richard M. Ransohoff,Bruce T. Lamb	381
15	Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease 2010 ·Neurobiology of Aging ·Brandy Wilkinson,Paige E. Cramer,Nicholas H. Varvel,Erin G. Reed-Geaghan,Qingguang Jiang,(unknown),Karl Herrup,Bruce T. Lamb,Gary E. Landreth	92
16	Photoreceptor Degeneration, Azoospermia, Leukoencephalopathy, and Abnormal RPE Cell Function in Mice Expressing an Early Stop Mutation inCLCN2 2010 ·Investigative Ophthalmology & Visual Science ·Malia M. Edwards,Caralina Marín de Evsikova,Gayle B. Collin,(unknown),Jiang Wu,Wanda L. Hicks,(unknown),Nicholas H. Varvel,Nicole Maphis,Bruce T. Lamb,Jürgen Κ. Naggert,Patsy M. Nishina,Neal S. Peachey	28
17	NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease 2009 ·Journal of Clinical Investigation ·Nicholas H. Varvel,Kiran Bhaskar,Maria Z. Kounnas,Steven L. Wagner,Yan Yang,Bruce T. Lamb,Karl Herrup	101
18	The Cleavage Products of Amyloid-β Precursor Protein Are Sorted to Distinct Carrier Vesicles That Are Independently Transported within Neurites 2009 ·Journal of Neuroscience ·Virgil Mureşan,Nicholas H. Varvel,Bruce T. Lamb,Zoia Muresan	59
19	Aβ Oligomers Induce Neuronal Cell Cycle Events in Alzheimer's Disease 2008 ·Journal of Neuroscience ·Nicholas H. Varvel,Kiran Bhaskar,Anita Patil,Sanjay W. Pimplikar,Karl Herrup,Bruce T. Lamb	115
20	Ectopic Cell Cycle Events Link Human Alzheimer's Disease and Amyloid Precursor Protein Transgenic Mouse Models 2006 ·Journal of Neuroscience ·Yan Yang,Nicholas H. Varvel,Bruce T. Lamb,Karl Herrup	148

About Nicholas H. Varvel

Nicholas H. Varvel is a scholar working on Neurology, Biological Psychiatry and Developmental Neuroscience, having authored 26 papers that have together received 2.1k indexed citations. Recurring topics across this work include Neuroinflammation and Neurodegeneration Mechanisms (15 papers), Alzheimer's disease research and treatments (14 papers) and Neuroscience and Neuropharmacology Research (7 papers). The work is most often cited by research in Neurology (1.1k citations), Biological Psychiatry (222 citations) and Developmental Neuroscience (161 citations). Nicholas H. Varvel has collaborated with scholars based in United States, Germany and Netherlands. Frequent co-authors include Bruce T. Lamb, Raymond Dingledine, Richard M. Ransohoff, Karl Herrup, Guixiang Xu, Astrid E. Cardona, F. Edward Dudek, Sung‐Ho Lee, Yan Yang and Jonas J. Neher. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Clinical Investigation and The Journal of Experimental Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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