Naoki Itano

8.2k total citations · 2 hit papers
75 papers, 6.6k citations indexed

About

Naoki Itano is a scholar working on Molecular Biology, Cell Biology and Cancer Research. According to data from OpenAlex, Naoki Itano has authored 75 papers receiving a total of 6.6k indexed citations (citations by other indexed papers that have themselves been cited), including 61 papers in Molecular Biology, 61 papers in Cell Biology and 13 papers in Cancer Research. Recurrent topics in Naoki Itano's work include Proteoglycans and glycosaminoglycans research (59 papers), Glycosylation and Glycoproteins Research (35 papers) and Fibroblast Growth Factor Research (32 papers). Naoki Itano is often cited by papers focused on Proteoglycans and glycosaminoglycans research (59 papers), Glycosylation and Glycoproteins Research (35 papers) and Fibroblast Growth Factor Research (32 papers). Naoki Itano collaborates with scholars based in Japan, United States and Thailand. Naoki Itano's co-authors include Koji Kimata, Theerawut Chanmee, Pawared Ontong, Kenjiro Konno, Takahiro Sawai, Michinari Hamaguchi, Mamoru Yoshida, Osamu Miyaishi, Shun’ichiro Taniguchi and Yoichi Yamada and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Neuroscience.

In The Last Decade

Naoki Itano

75 papers receiving 6.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment

2014 1.2k citations Theerawut Chanmee, Pawared Ontong et al. profile →
Three Isoforms of Mammalian Hyaluronan Synthases Have Distinct Enzymatic Properties

1999 736 citations Naoki Itano, Takahiro Sawai et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Naoki Itano Japan	38	3.7k	3.6k	1.2k	1.1k	821	75	6.6k
Johan Kreuger Sweden	28	4.1k 1.1×	2.0k 0.5×	593 0.5×	931 0.8×	920 1.1×	57	6.3k
José L. Jorcano Spain	53	4.5k 1.2×	2.4k 0.7×	812 0.7×	1.5k 1.3×	860 1.0×	139	9.2k
Alberto Passi Italy	43	2.9k 0.8×	3.1k 0.9×	456 0.4×	640 0.6×	920 1.1×	156	6.3k
Spyros S. Skandalis Greece	32	2.5k 0.7×	2.1k 0.6×	442 0.4×	942 0.8×	893 1.1×	61	5.5k
Richard Grose United Kingdom	35	4.7k 1.3×	1.5k 0.4×	753 0.6×	1.3k 1.2×	1.1k 1.3×	77	9.4k
Ming‐Jer Tang Taiwan	50	3.4k 0.9×	1.9k 0.5×	443 0.4×	1.0k 0.9×	638 0.8×	173	6.8k
Ofer Reizes United States	30	3.1k 0.8×	2.4k 0.7×	424 0.4×	894 0.8×	725 0.9×	86	5.4k
Thomas Maciag United States	37	5.3k 1.4×	1.9k 0.5×	824 0.7×	741 0.7×	1.0k 1.2×	63	7.3k
Erik H.J. Danen Netherlands	42	3.4k 0.9×	2.2k 0.6×	906 0.8×	1.4k 1.3×	1.0k 1.2×	120	6.7k
Kayla J. Bayless United States	42	2.9k 0.8×	1.3k 0.4×	917 0.8×	554 0.5×	957 1.2×	100	5.7k

Countries citing papers authored by Naoki Itano

Since Specialization

Citations

This map shows the geographic impact of Naoki Itano's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Naoki Itano with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Naoki Itano more than expected).

Fields of papers citing papers by Naoki Itano

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Naoki Itano. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Naoki Itano. The network helps show where Naoki Itano may publish in the future.

Co-authorship network of co-authors of Naoki Itano

This figure shows the co-authorship network connecting the top 25 collaborators of Naoki Itano. A scholar is included among the top collaborators of Naoki Itano based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Naoki Itano. Naoki Itano is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kobayashi, Takashi, Hisatoshi Hanamatsu, Ryo Ushioda, et al.. (2024). Tolerable glycometabolic stress boosts cancer cell resilience through altered N-glycosylation and Notch signaling activation. Cell Death and Disease. 15(1). 53–53. 5 indexed citations

Itano, Naoki, et al.. (2022). Dysregulation of hexosamine biosynthetic pathway wiring metabolic signaling circuits in cancer. Biochimica et Biophysica Acta (BBA) - General Subjects. 1867(1). 130250–130250. 14 indexed citations

Kobayashi, Takashi, et al.. (2019). Enhanced hexosamine metabolism drives metabolic and signaling networks involving hyaluronan production and O-GlcNAcylation to exacerbate breast cancer. Cell Death and Disease. 10(11). 803–803. 37 indexed citations

Chanmee, Theerawut, Pawared Ontong, Tomomi Izumikawa, et al.. (2016). Hyaluronan Production Regulates Metabolic and Cancer Stem-like Properties of Breast Cancer Cells via Hexosamine Biosynthetic Pathway-coupled HIF-1 Signaling. Journal of Biological Chemistry. 291(46). 24105–24120. 68 indexed citations

Ikuta, Togo, Yasuhito Kobayashi, Masato Kitazawa, et al.. (2013). ASC-associated inflammation promotes cecal tumorigenesis in aryl hydrocarbon receptor-deficient mice. Carcinogenesis. 34(7). 1620–1627. 52 indexed citations

Ontong, Pawared, et al.. (2013). Effect of a cholesterol-rich lipid environment on the enzymatic activity of reconstituted hyaluronan synthase. Biochemical and Biophysical Research Communications. 443(2). 666–671. 15 indexed citations

Kobayashi, Nobutaka, Hiroshi Koyama, Masato Kitazawa, et al.. (2010). Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and Tumor Neovascularization. Cancer Research. 70(18). 7073–7083. 155 indexed citations

Hirayama, Yukio, Mamiko Yoshimura, Yuriko Ozeki, et al.. (2009). Mycobacteria Exploit Host Hyaluronan for Efficient Extracellular Replication. PLoS Pathogens. 5(10). e1000643–e1000643. 29 indexed citations

Itano, Naoki, Lisheng Zhuo, & Koji Kimata. (2008). Impact of the hyaluronan‐rich tumor microenvironment on cancer initiation and progression. Cancer Science. 99(9). 1720–1725. 122 indexed citations

10.

Itano, Naoki. (2008). Simple Primary Structure, Complex Turnover Regulation and Multiple Roles of Hyaluronan. The Journal of Biochemistry. 144(2). 131–137. 107 indexed citations

11.

Koyama, Hiroshi, Nobutaka Kobayashi, Michiko Takeoka, et al.. (2007). Significance of Tumor-Associated Stroma in Promotion of Intratumoral Lymphangiogenesis. American Journal Of Pathology. 172(1). 179–193. 100 indexed citations

12.

Zhuo, Lisheng, Akiko Kanamori, Reiji Kannagi, et al.. (2006). SHAP Potentiates the CD44-mediated Leukocyte Adhesion to the Hyaluronan Substratum. Journal of Biological Chemistry. 281(29). 20303–20314. 136 indexed citations

13.

Itano, Naoki. (2004). Abnormal Hyaluronan Synthesis and Cancer Progression. Trends in Glycoscience and Glycotechnology. 16(89). 199–210. 7 indexed citations

14.

Itano, Naoki, Takahiro Sawai, Fukiko Atsumi, et al.. (2004). Selective Expression and Functional Characteristics of Three Mammalian Hyaluronan Synthases in Oncogenic Malignant Transformation. Journal of Biological Chemistry. 279(18). 18679–18687. 114 indexed citations

15.

Yamada, Yoichi, Naoki Itano, Hisashi Narimatsu, et al.. (2004). Elevated transcript level of hyaluronan synthase1 gene correlates with poor prognosis of human colon cancer. Clinical & Experimental Metastasis. 21(1). 57–63. 41 indexed citations

16.

Itano, Naoki. (2001). Hyaluronan Biosynthesis:A Multifaceted Process(Special Issue on "Hyaluronan"). 33(3). 221–226. 1 indexed citations

17.

Ichikawa, Takeshi, Naoki Itano, Takahiro Sawai, et al.. (1999). Increased Synthesis of Hyaluronate Enhances Motility of Human Melanoma Cells. Journal of Investigative Dermatology. 113(6). 935–939. 59 indexed citations

18.

Itano, Naoki & Koji Kimata. (1998). Hyaluronan Synthase: New Directions for Hyaluronan Research.. Trends in Glycoscience and Glycotechnology. 10(51). 23–38. 14 indexed citations

19.

Itano, Naoki, Kayoko Oguri, Hayao Nakanishi, & Minoru Okayama. (1993). Membrane-Intercalated Proteoglycan of a Stroma-Inducing Clone from Lewis Lung Carcinoma Binds to Fibronectin Via Its Heparan Sulfate Chains1. The Journal of Biochemistry. 114(6). 862–873. 12 indexed citations

20.

Nakanishi, Hayao, Kayoko Oguri, Keiichi Yoshida, et al.. (1992). Structural differences between heparan sulphates of proteoglycan involved in the formation of basement membranes in vivo by Lewis-lung-carcinoma-derived cloned cells with different metastatic potentials. Biochemical Journal. 288(1). 215–224. 32 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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